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A novel coumarin based azo-phenol ligand (H 2 L) has been synthesized and characterized by several spectroscopic techniques. An almost 16 fold enhancement of emission intensity has been observed upon gradual addition of Mg 2+ to H 2 L in DMSO:H 2 O (1:5 v/v) medium while it has no significant effect in emission intensity even in presence of other metal ions. The emission intensity of L-Mg 2+ complex has almost quenched on gradual addition of F − to it. The limit of detection for both Mg 2+ and F − are of 10 −8 M order, hence the newly developed chemosensor is highly efficient in detecting Mg 2+ and F − in very minute levels. The chemosensor can even detect Mg 2+ in the intracellular region of human lung cancer cells (A549 cells). [ABSTRACT FROM AUTHOR]

A highly sensitive and selective coumarin based chemosensor H 2 L for the efficient detection of Al 3+ has been developed. The synthesized chemosensor H 2 L is efficient in detecting Al 3+ over other metal ions which are commonly obtained in various physiological and environmental samples. H 2 L shows fluorescence ‘turn-on’ response at 610 nm in presence of Al 3+ , without the interference of other metal ions. The resulting H 2 L-Al 3+ complex behave as a sequential chemosensor for F − , by showing quenching of emission intensity upon addition of F − to it. This quenching of emission intensity is only specific for F − and is not hampered due to the presence of other anions that commonly coexist with F − in various environmental solutions. Theoretical calculations using DFT/B3LYP method has been used to get insight into the sensing mechanism as well as electronic structure of the synthesized chemosensor H 2 L. H 2 L is efficient in detecting Al 3+ in the intracellular region of human A549 cell and also exhibits an INHIBIT logic gate with Al 3+ and F − as chemical inputs by monitoring the emission mode at 610 nm. [ABSTRACT FROM AUTHOR]