1. Di-tert-butylazodicarboxylate based PVC membrane sensor for Fe(III) ion measurement in pharmaceutical formulation
- Author
-
Masrournia, Mahboubeh, Zamani, Hassan Ali, Mirrashid, Hassan Ali, Ganjali, Mohammad Reza, and Faridbod, Farnoush
- Subjects
- *
CARBOXYLIC acids , *POLYVINYL chloride , *ARTIFICIAL membranes , *ELECTROCHEMICAL sensors , *IRON ions , *SOLUTION (Chemistry) , *IONOPHORES , *MIXTURES , *IRON electrodes - Abstract
Abstract: Preliminary solution study shows the selectivity of di-tert-butylazodicarboxylate (TBADC) toward Fe(III) ions. Due to this selectivity, it was applied as an ionophore for construction of a Fe(III) sensor. The proposed sensor exhibits a wide linear response range with a Nerstian slope of 19.4±0.4mVdecade−1 and detection limit of 4.8×10−8 molL−1. The sensor response is pH independent in the range of 2.3–3.4 and has a fast response time of <10s. It also shows very good selectivity to Fe(III) ion over many mono-,di- and trivalent transition and heavy metal ions. The life time of the electrode was at least 10weeks. The application of the TBADC-based sensor to analysis of Fe(III) ion in a pharmaceutical formulation, and also to the monitoring of Fe(III) ion in mixtures of two, three and four different ions showed satisfactory results. [Copyright &y& Elsevier]
- Published
- 2011
- Full Text
- View/download PDF