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The purpose of this paper was to shed light on the main barriers to caring pedagogical relationships within simulation centers from the perspective of nursing students and offer targeted strategies to reduce these barriers. A caring pedagogical relationship is a powerful strategy to foster students' learning within simulation settings. However, the development of this relationship could be hindered if nurse educators are not aware of its barriers. Hence, this could affect students' learning and well-being within this academic context. According to our knowledge, no previous research has addressed the question of the barriers to caring pedagogical relationships within the context of simulation. This study employed a descriptive phenomenological method, entitled Relational Caring Inquiry, to collect and analyze data gathered from 19 students enrolled in an undergraduate nursing program. This paper focuses on one eidos-theme that emerged from our data analysis and interpretation entitled "Educator's conscientization regarding barriers to the development of a caring pedagogical relationship". According to data analysis and interpretation, this eidos-theme was the most emphasized by research participants. It emerged from the following themes: (a) educators' dehumanizing practices, (b) disruptive and stressful academic context, (c) lack of educators' experiences and (d) educators' disinterest in students' learning. Leaving caring pedagogical relationships' barriers unaddressed has shown adverse impacts on students' learning process and their mental and physical well-being. This paper brings to light the main barriers to caring pedagogical relationships and invites educators, managers and nurse leaders to be aware of these obstacles and collectively engage in humanizing nursing education. In other words, we emphasize the impact of these barriers on students' apprenticeship and suggest political actions to build caring and inclusive simulation environments. CERSES-19–050-D. [ABSTRACT FROM AUTHOR]

The purpose of this study was to investigate the effects of holding external loads on postural sway during upright stance across age decades. Sixty-five healthy adults (females, n = 35), aged 18-80 years were assessed in four conditions; (1) standing without holding a load, holding a load corresponding to 5% body mass in the (2) left hand, (3) right hand and (4) both hands. The centre of pressure (COP) path length and anteroposterior and mediolateral COP displacement were used to indirectly assess postural sway. External loading elicited reductions in COP measures of postural sway in older age groups only (P < 0.05). No changes were observed in younger or intermediate aged adults (P > 0.05). Holding external loads during standing is relevant to many activities of daily living (i.e. holding groceries). The reduction in postural sway may suggest this type of loading has a stabilising effect during quiet standing among older adults. [ABSTRACT FROM AUTHOR]

To describe the practical experience of delivering a proactive and integrated consultation-liaison (C-L) psychiatry service model (PICLP). PICLP is designed for older medical inpatients and is explicitly biopsychosocial and discharge-focused. In this paper we report: (a) observations on the training of 15 clinicians (seven senior C-L psychiatrists and eight assisting clinicians) to deliver PICLP; (b) the care they provided to 1359 patients; (c) their experiences of working in this new way. A mixed methods observational study using quantitative and qualitative data, collected prospectively over two years as part of The HOME Study (a randomized trial comparing PICLP with usual care). The clinicians were successfully trained to deliver PICLP according to the service manual. They proactively assessed all patients and found that most had multiple biopsychosocial problems impeding their timely discharge from hospital. They integrated with ward teams to provide a range of interventions aimed at addressing these problems. Delivering PICLP took a modest amount of clinical time, and the clinicians experienced it as both clinically valuable and professionally rewarding. The experience of delivering PICLP highlights the special role that C-L psychiatry clinicians, working in a proactive and integrated way, can play in medical care. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Medical Imaging & Radiation Sciences is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Whenever the policy challenges to address ask for a strong scientific background, decision makers depend on the underlying research activities. One of the fields in which research is able to affect the design and implementation of policies is given by the Circular Economy (CE). Our purpose in this paper is to understand how scholars carry out their research in the CE to realize whether a common pattern emerge and identify implications for policy. We provide a systematic investigation of the world's ten largest national research communities (NRCs) to highlight differences and similarities and understand the underlying patterns of research. We refer to eight key dimensions, which are mostly original ones and, therefore, represent elements of novelty of the paper: internationality, interdisciplinarity, specialization, relevance of local issues, policy implications, provision of case studies, research focus and research method. A dataset with 3027 CE-related research publications that range from 2001 to 2018 has been used for the elaborations. Results show some similarities and differences: everywhere, the empirical method prevails over the theoretical, and research is mostly focused on the micro-level of analysis (e.g., consumers and firms), while national research communities differ with respect to the openness to international collaborations, the degree with which some specific disciplines contribute to research in the field of CE, and the consideration of local issues provide. • A cross-country comparison of national research communities (NRCs) studying CE is offered. • NRCs are compared along eight key-dimensions using eleven indicators. • Empirical methods prevail over theory and research focus is on micro-level analyses. • Differences emerge with respect to interdisciplinarity and attention to local issues. • China, US, and European countries are moving along diverse research trajectories. [ABSTRACT FROM AUTHOR]

With the development of Internet and multimedia development, digital image steganography is becoming more extensive in transmitting data with high capacity and security. Although there have been some relevant surveys, there is a lack of relevant surveys on Deep-Learning-based image steganography recently, especially for the developments and perspectives on generative steganography and reversible steganography. So this paper fills this gap and investigates recent developments in Deep-Learning-based image steganography from the viewpoints of strategy and network structures, which is summarized and categorized into ten strategies and five network models. In particular, this paper summarizes the relative merits and challenges of the leading techniques and discusses the research prospect of these fields for promoting the development of steganography. • Image steganography safeguard data from unauthorized access. • The strategies of Image steganography are summarized and classified. • Network structures are summarized and classified for image steganography. • An outlook is discussed on future research work. [ABSTRACT FROM AUTHOR]

For a complete, harmonized and modernized land administration processes, seamless data exchange among departments within an organization, and among organizations is a fundamental requirement. Interoperability is therefore crucial and should be based on a well-developed Land Administration Domain Model (LADM) country profile for the implementation of a Land Administration System (LAS). This paper, through a research synthesis type of literature review methodology, looks into the existing documentation on interoperability in Land Administration (LA). Employing research synthesis method, analysis of the identified and existing resources is done. Since interoperability plays a role at multiple levels, it is paramount to apply a solid framework such as the Framework for Enterprise Interoperability (FEI) developed by International Standards Organization (ISO). This allows for the investigation of the critical aspects of data exchange: (i) business, processes, services and data, (ii) interoperability barriers: conceptual, technological and organizational, and (iii) interoperability approaches: federated, unified and integrated. The paper looks into the interoperability concerns and barriers and the approaches to addressing them for Land Administration against the elements of FEI. This provides an effective guideline for implementation of a LADM-based land administration system for any country. • Developing a framework for Data Exchange and interoperability for land administration system. • Use of LADM country profile as a foundation for data exchange and interoperability inland administration. • Using ISO 11354–1:2011, Framework for enterprise interoperability as a guideline for interoperability in land administration. • LADM county profile and interoperability framework are pillars for successful Implementation of land administration system. [ABSTRACT FROM AUTHOR]

Time to event outcomes is commonly encountered in epidemiologic research. Multiple papers have discussed the inadequacy of using the hazard ratio as a causal effect measure due to its noncollapsibility and the time-varying nature. In this paper, we further clarified that the hazard ratio might be used as a conditional causal effect measure, but it is generally not a valid marginal effect measure, even under randomized design. We proposed to use the restricted mean survival time (RMST) difference as a causal effect measure, since it essentially measures the mean difference over a specified time horizon and has a simple interpretation as the area under survival curves. For observational studies, propensity score adjustment can be implemented with RMST estimation to remove observed confounding bias. We proposed a propensity score stratified RMST estimation strategy, which performs well in our simulation evaluation and is relatively easy to implement for epidemiologists in practice. Our stratified RMST estimation includes two different versions of implementation, depending on whether researchers want to involve regression modeling adjustment, which provides a powerful tool to examine the marginal causal effect with observational survival data. [ABSTRACT FROM AUTHOR]

Transitioning to a low carbon energy future is essential to meet the Paris Agreement targets and Sustainable Development Goals (SDGs). To understand how societies can undertake this transition, energy models have been developed to explore future energy scenarios. These models often focus on the techno-economic aspects of the transition and overlook the long-term implications on both society and the natural environment. Without a holistic approach, it is impossible to evaluate the trade-offs, as well as the co-benefits, between decarbonisation and other policy goals. This paper presents the Energy Scenario Evaluation (ESE) framework which can be used to assess the impact of energy scenarios on society and the natural environment. This conceptual framework utilises interdisciplinary qualitative and quantitative methods to determine whether an energy scenario is likely to lead to a publicly acceptable and sustainable energy transition. Using the SDGs, this paper illustrates how energy transitions are interconnected with human development and the importance of incorporating environmental and socio-economic data into energy models to design energy scenarios which meet other policy priorities. We discuss a variety of research methods which can be used to evaluate spatial, environmental, and social impacts of energy transitions. By showcasing where these impacts will be experienced, the ESE framework can be used to facilitate engagement and decision-making between policymakers and local communities, those who will be directly affected by energy transitions. Outputs of the ESE framework can therefore perform an important role in shaping feasible and energy transitions which meet the Paris Agreement targets and SDGs. • Energy models do not give sufficient attention to social and environmental impacts. • Our ESE framework uses an interdisciplinary approach to energy scenario evaluation. • Using multiple methods, the ESE framework considers how impacts vary spatially. • A social licence to operate will be key to the success of net-zero transitions. [ABSTRACT FROM AUTHOR]

Presently, child-specific tools and instruments related to active school travel (AST) are lacking. This methodological shortcoming often contributes to suboptimal AST behaviour evaluations and intervention programming. The aim of this paper was to develop and validate a theoretically informed child-specific scale regarding multiple perceived barriers and enablers known to impact children's participation in AST. Mixed methods. A mixed-methods and multistudy scale development approach featuring the application of social-ecological theory, a validation pilot study (n = 80), and test-retest study (n = 96) was conducted in collaboration with children in Ontario, Canada. In tandem with completing cognitive interviews and online surveys, multiple analyses, including a qualitative thematic analysis, along with weighted Cohen's kappa, Cronbach's alpha, and confirmatory factor analysis were undertaken. Qualitative analyses of the developed tool addressed face validity concerns related to the response options and definitions of terms used. Following the reliability analyses of 40 items, two confirmatory factor analyses were run to assess the construct validation of perceived AST barriers and enablers, and resulted in the development of the 24-item Perceived Active School Travel Enablers and Barriers – Child (PASTEB-C) questionnaire. The developed PASTEB-C questionnaire may be used to inform the programming and development of AST interventions, as well as conduct child-specific AST research. [ABSTRACT FROM AUTHOR]

Since the mid-1980s, Australia has resettled thousands of African refugees. This paper focuses on the racialization of youth violence and the damage it sustains on refugee-background young Africans. The discussion proceeds in two interrelated stages. In the first stage, to understand the representation of African youth in the public sphere, the paper reviews the relevant literature, media headlines, and political commentaries. In so doing, it establishes that the continual framing of African youth as dangerous and violence-prone by conservative politicians and media outlets amounts to racial moral panic. In the second stage, guided by narrative research methodology, a small group of young Africans were invited to reflect on their everyday life under racialized frames. Accounts of the youth are presented under four themes: the presumption of guilt, emotional ill-being, opportunity hoarding, and the permanence of otherness. It is argued that, if left unaddressed, the racialization of youth violence can diminish the integration outcomes of African youth. [ABSTRACT FROM AUTHOR]

Background: Misophonia is a condition marked by dysregulated emotions and behaviors in response to trigger sounds, often chewing, breathing, or coughing. Evidence suggests that misophonia develops in adolescence and the emotions and behaviors are a conditioned response to distress, resulting in social avoidance, stress, and family conflict. In addition, co-occurrence with other psychiatric illnesses such as anxiety, OCD, and Tourette syndrome is common. A transdiagnostic cognitive behavioral therapeutic (CBT) approach appears appropriate. There are currently no controlled studies of youth with misophonia. The current paper describes the approach to a pilot randomized, blinded family-based treatment study for youth ages 8-16 years. Preliminary results from a pilot open trial also are described.Methods: A 2-phase dual site telehealth treatment study using a transdiagnostic CBT approach, the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents (UP-C/A; Ehrenreich-May et al., 2018), is proposed. Phase 1 consisted of a 4-case pilot of UP-C/A. Phase 2 includes a randomized trial comparing the UP-C/A to a standard relaxation and education protocol.Results: Preliminary results from the pilot show modest improvements in evaluator-rated misophonia symptoms on the Clinical Global Impression Severity and Improvement scales.Limitations: There is little research to inform evidence-based practice for youth with misophonia. Study limitations include lack of standardized misophonia assessment instruments and an absence of formal diagnostic criteria.Conclusions: The current paper describes proposed methods for the first randomized controlled trial for youth with misophonia and their families along with results from a 4-case pilot. [ABSTRACT FROM AUTHOR]

Aim: To validate the paper grip test for assessing plantar flexion strength of the hallux.Methods: Plantar flexor strength for 69 people with diabetic neuropathy was assessed: (a) using the paper grip test while simultaneously a plantar pressure platform quantified the force under the hallux, and (b) using a hand-held dynamometer. Following testing, participants were divided into groups: (1) passed vs. failed paper grip test (2) males vs. females. Statistical analyses determined if differences were evident between the groups and assessed the relationship between the paper grip test and the hand-held dynamometer. The discrimination ability, sensitivity, specificity, and reproducibility of the paper grip test was established.Results: Participants who passed the paper grip test demonstrated greater grip force at the hallux than those who failed, and they also exhibited greater isometric maximum force during the hand-held dynamometry test (p ≤ 0.05). Grip force for males was significantly higher than for females. A moderate positive correlation between the paper grip test and the hand-held dynamometer was evident.Conclusions: In the population examined the paper grip test was found to be a valid clinical tool; it offers a non-invasive, inexpensive, and quick method to assess plantar flexion strength of the hallux. [ABSTRACT FROM AUTHOR]

Objective: The aim of this paper is to examine the effects of an educational peer-group intervention on knowledge about dementia, perceived ability to talk about it, received support and self-perceived pressure from informal care among family caregivers with a Turkish or Moroccan immigrant background who cared for a person with dementia.Methods: This paper is based on a cluster randomised controlled trial with three measures, including participants who knew or cared for a person with dementia. For the purpose of this study, a selection was made of participants who cared for a person with dementia. Knowledge about dementia, perceived ability to talk about dementia, support received and self-perceived pressure from informal care were assessed inthe intervention and the control condition. Multi-level analyses were conducted to examine the effects.Results: Data for 386 participants was analysed. Improvement in knowledge about dementia over time was significantly greater in the intervention condition than in the control condition. In the intervention condition, there was also a significant increase over time in the support received from home-care staff, which was not found in the control condition. No effects were found on other types of support received, the ability to talk about dementia or the self-perceived pressure from informal care.Conclusion: Offering a culturally sensitive educational peer-group education intervention enhances knowledge about dementia and has a small but positive effect on the support received from home-care staff in these groups.Practice Implications: Offering peer-group-based education about dementia to family caregivers with Turkish or Moroccan immigrant backgrounds is important for multicultural dementia care. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Medical Imaging & Radiation Sciences is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Introduction: The Netherlands Study of Depression and Anxiety (NESDA, www.nesda.nl) is a longitudinal, multi-site, naturalistic, case-control cohort study set up to examine the etiology, course and consequences of depressive and anxiety disorders. This paper presents a cohort profile of NESDA.Methods and Results: The NESDA sample recruited initially 2329 persons with a remitted or current DSM-IV based depressive (major depressive disorder, dysthymia) and/or anxiety disorder (panic disorder, social phobia, agoraphobia, generalized anxiety disorder), 367 of their siblings and 652 healthy controls, yielding a total of 3348 participants. Half-day face-to-face assessments of participants started in 2004 and since then have been repeated six times over a period of 9 years. A 13-year follow-up assessment is ongoing, at what time we also recruit offspring of participants. Retention rates are generally high, ranging from 87.1% (after 2 years) to 69.4% (after 9 years). Psychiatric diagnostic interviews have been administered at all face-to-face assessments, as was monitoring of clinical characteristics, psychosocial functioning and somatic health. Assessed etiological factors include e.g. early and current environmental risk factors, psychological vulnerability and resilience factors as well as (neuro)biology through hypothesis-driven biomarker assessments, genome-wide and large-scale '-omics' assessments, and neuroimaging assessments.Limitations: The naturalistic design allows research into course and consequences of affective disorders but is limited in treatment response interpretation.Conclusions: NESDA provides a strong research infrastructure for research into depressive and/or anxiety disorders. Its data have been used for many scientific papers describing either NESDA-based analyses or joint collaborative consortia-projects, and are in principle available to researchers outside the NESDA consortium. [ABSTRACT FROM AUTHOR]

Populism has emerged as a central explanation employed by both media outlets and scholars for the mishandling of the COVID-19 crisis. Nonetheless, the relationship between public health and populism extends before and beyond the pandemic. This paper offers a comprehensive overview of existing evidence and theoretical conceptualisations on the intersection of populism, health emergencies, and contrarian scientific positions, drawing from a diverse range of disciplines. I conducted a scoping review of 283 original studies, analysing their analytical framework, geographic focuses, and methodological approaches. Employing quantitative text analysis, I summarised the research field into 18 common topics, organised into five coherent categories: citizen's perspective, political elites, political communication, pandemic consequences, and non-COVID-related issues. While the scholarly interest in this area has surged since the onset of the pandemic, it has predominantly concentrated on specific cases, such as Brazil and the US, often conflating different policy types. The evidence summary elucidates that populism assumes varying roles within distinct contexts, and there is no linear relationship between political populism and specific approaches to health crises and science. I further compare definitions of populism within the context of health and scientific positions. I propose that future research should employ a policy typology for health emergency responses, assessing political positions based on policy arenas. This paper contributes to the understanding of the complex interplay between political populism, contrarian scientific perspectives, and public health. • Descriptive summary of multiple disciplines and theoretical frameworks. • Research interest in this theme surged after the COVID-19 pandemic. • Geographic focus and generalisation of specific cases such as Brazil and the US. • Lack of linear and universal association between populism and health emergencies. • Adoption of a common policy typology to guide future research. [ABSTRACT FROM AUTHOR]

The aim of the study was to assess the usefulness of analysing visual material in a 3D environment when examining spatial interrelations between the incident participants, tools, and space surrounding the incident site. Such analysis may provide information about the trauma mechanism, which may lead to the determination of probable events. This paper points to the potential of conducting research under 3D environment conditions on the example of a specific criminal incident—a suspected homicide. The aim of the study was to identify possible circumstances of the events with particular emphasis on the mechanism of death and the involvement of third parties. It was performed a comprehensive 3D reconstruction of the elements of the incident using different sources and forms of evidence, and consequently also different imaging, analysis, and synthesis technologies. The resulting 3D reconstruction and animation of the possible events serve to verify the investigative hypotheses. The paper combines a technical description of the research methodology with a forensic commentary, which ultimately creates an integral synthesis of the medicolegal assessment for trial purposes, while presenting the effectiveness of the research methods used. To sum up, the paper presents an experiment carried out under virtual conditions, impossible to execute under real conditions but critical for trial case analysis. • 2D and 3D image recording as material for medico-legal assessment. • 3D reconstruction and synthesis on physical as well as archival visual material. • Effectiveness of 3D reconstruction and the quality of evidence. [ABSTRACT FROM AUTHOR]

Gifts are a powerful way to acknowledge and strengthen interpersonal relationships. As with any relational space, gifting plays various roles in forming and maintaining relationships in political contexts, but its contribution to relationship-building has attracted little attention. This paper examines how politicians in Aotearoa New Zealand both engage with gifting and how they navigate the perceptions of others. Four current members of parliament (MPs) and six retired MPs participated in semi-structured interviews with questions on common practices and common understandings about political gifting. Their responses indicate their use of four different processes: formal processes are the guidelines provided by the government on gifting, but when these are insufficient, contextual processes regarding perceptions of the media, constituents or colleagues are used, or, alternatively, MPs rely on personal values or view gifting in terms of transactional processes with both parties receiving benefits. The paper explores perceptions and complexities of a sequence of gifts during events (event gifting). The authors recommend an improved awareness and understanding of the contribution of gifting practices to political relationship building. [ABSTRACT FROM AUTHOR]

• Inclined stiffened panels of the fuselage tail were tested under shear load. • The simulation model was established to predict the buckling, post-buckling, and failure modes of inclined stiffened composite panels. • The non-linear relationship between the debonding of the stiffeners and the skin was quantitatively analyzed. • The concept of equivalent skin thickness was introduced to analyze the influence of stringer configuration on panel buckling and post-buckling. The purpose of this paper is to investigate the buckling and post-buckling behavior of inclined stiffened composite panels under shear load. Two types of stiffened composite panels were manufactured and tested. The buckling load, ultimate load and other required structural properties of the inclined stiffened composite panels were obtained. The test results show that the failure load of the two types of panels are 5.79 times and 11.2 times of the buckling load, respectively, indicating that such inclined stiffened panels have a large post-buckling capacity. The damage modes of the panel are tearing around the skin near the clamps and debonding of the stringers from the skin. The combination of Hashin failure criterion, Cohesive model and nonlinear connection of clamp was used to conduct finite element modeling, which effectively predicts the buckling, post-buckling and damage modes of the structure. The buckling and post-buckling behavior of stiffened panels with different stinger configurations were discussed based on finite element analysis. The results show that when the initial buckling occurs between the stringers, the buckling and failure load of the stiffened panel become larger as the equivalent skin thickness between the stringers become larger. The research in this paper can provide reference for aircraft structural design. [ABSTRACT FROM AUTHOR]

• Permanent supportive housing (PSH) is one setting which aims to provide stability and community to those who have experienced homelessness. • PSH has not been widely studied with young adults. • This paper uses mixed method to explore how young adult residents experience psychological sense of community (PSOC) before and after moving into PSH. • We find that building community takes time and requires opportunities for voices to be heard, along with ongoing personal growth (often related to substance use recovery). • Future PSH settings for young people should consider how to support residents in their individual journeys, and in building community. Amidst chronic stressors and ongoing instability, many young people who have experienced homelessness and housing instability find communities and settings which offer support and care. Permanent Supportive Housing (PSH) is one setting which aims to provide stability and community to those who have experienced homelessness, but it has not been widely studied with young adults (ages 18–25 upon moving into PSH). This paper employs a longitudinal convergent mixed methods approach – with quantitative and qualitative survey data over 1.5 years – to explore how young adult residents (N = 27 at T1; N = 20 at T2, N = 13 at T3) experience sense of community before and after moving into PSH. Using McMillan and Chavis' (1986) four-part Psychological Sense of Community (PSOC) framework to frame data collection and analysis, we find that residents' sense of community is shaped by an ongoing negotiation of personal and collective needs. Building community takes time and requires opportunities for voices to be heard (and shape change), along with ongoing personal growth – especially related to substance use recovery. Our findings offer insights for future PSH settings for young people – as well as other residential and community settings which aim to support young people. We suggest the need for future research which explores the tension of policy decision making, about substance use for example, in low-barrier support services like PSH. [ABSTRACT FROM AUTHOR]

This paper introduces an innovative method for enhanced researcher reflexivity: the use of synchronous collective writing as a space to collaboratively reflect on experiences of subjectification within the contemporary academy. We explore how, despite its apparent importance to contemporary research, the neoliberalisation of academia leaves little room for meaningful reflexivity. The authors in this paper – ranging from Master's student to postdoctoral researcher – wrote collaboratively in real-time to organically develop a method of collective reflexivity. Through auto-ethnographic vignettes that act as raw data, and a critical analysis of how we came to experience the events showcased in these vignettes, we analyse how our positionalities shape both our subjection to, and perpetuation of, systems of symbolic violence in neoliberal academic institutions. Through this method, we explore experiences of the contemporary university as patriarchal, intensively marketised, and as a space where the prevalence of 'weak' reflexivity has negative impacts on research ethics. We argue that the affect of collaborative writing spaces acts as a resistance against our experiences of loneliness, competition and individualism. We also argue our new approach fosters research that is more responsive to the socio-material conditions to which it attends, and enables a deeper engagement with affect-led methodologies and slow-research. • Recuperating reflexivity from neoliberal co-option. • Embodied affects as a guide for reflexivity. • Collective synchronous writing against neoliberal subjectification of academics. • Auto-ethnographic exploration of navigating modern research. • Questioning power dynamics of field research and the neoliberal academy. [ABSTRACT FROM AUTHOR]

This paper about social media platforms of Swiss hospitals refers to the period between 10 February 2020 and 6 July 2020. The study included in-depth insights into the use of platforms, content analyses of posts and resonance of the posts. The study's objective was to get insights into social media post creation by and corresponding resonance in pandemic crisis. This study included collection and analyses of posts created by a selection of Swiss hospitals during the period of study. All university hospitals and a variety of private and regional hospitals in all regions of Switzerland are represented. The data collection started before the official shutdown in Switzerland. This study used mixed method approach and content analysis to evaluate 2,326 posts during the study period related to the COVID-19 pandemic. During the first phase of the pandemic, hospitals used social media platforms more frequently than normal. Especially in the first month, the number of posts rose disproportionally. The numbers dropped back to the initial situation after only 4 months into the COVID-19 pandemic. Most hospitals used Facebook and Twitter, whereas Instagram and YouTube's use were marginal. University hospitals used social media platforms differently than regional hospitals. Most posts generated only a very low response with a median of 2. Hospitals were therefore not able to create engagement of their followers. However, hospitals that publish actively were able to build a more active community. Only a small number of posts led to heated discussions in the comments. These viral posts shared information on the illness, the vaccination, children and COVID-19. [ABSTRACT FROM AUTHOR]

Aims: We recently reported early outcomes in patients enrolled in a randomised trial of adrenaline in out-of-hospital cardiac arrest: the PARAMEDIC2 (Prehospital Assessment of the Role of Adrenaline: Measuring the Effectiveness of Drug Administration in Cardiac Arrest) trial. The purpose of the present paper is to report long-term survival, quality of life, functional and cognitive outcomes at 3, 6 and 12-months.Methods: PARAMEDIC2 was a pragmatic, individually randomised, double blind, controlled trial with an economic evaluation. Patients were randomised to either adrenaline or placebo. This paper reports results on the modified Rankin Scale scores at 6-months, survival at 6 and 12-months, as well as other cognitive, functional and quality of life outcomes collected at 3 and 6 months (Two Simple Questions, the Mini Mental State Examination, the Informant Questionnaire on Cognitive Decline Evaluation for Cardiac Arrest, Hospital Anxiety and Depression Scale, the Post Traumatic Stress Disorder Checklist - Civilian Version, Short-Form 12-item Health Survey and the EuroQoL EQ-5D-5L).Results: 8014 patients were randomised with confirmed trial drug administration. At 6-months, 78 (2.0%) of the patients in the adrenaline group and 58 (1.5%) of patients in the placebo group had a favourable neurological outcome (adjusted odds ratio 1.35 [95% confidence interval: 0.93, 1.97]). 117 (2.9%) patients were alive at 6-months in the adrenaline group compared with 86 (2.2%) in the placebo group (1.43 [1.05, 1.96], reducing to 107 (2.7%) and 80 (2.0%) respectively at 12-months (1.38 [1.00, 1.92]). Measures of 3 and 6-month cognitive, functional and quality of life outcomes were reduced, but there was no strong evidence of differences between groups.Conclusion: Adrenaline improved survival through to 12-months follow-up. The study did not find evidence of improvements in favourable neurological outcomes. (ISCRTN 73485024). [ABSTRACT FROM AUTHOR]

Introduction: Around 23% of adults worldwide are insufficiently active. Wearable devices paired with virtual coaching software could increase physical activity. The effectiveness of 3 minimal contact interventions (paper-based physical activity diaries, activity trackers, and activity trackers coupled with virtual coaching) in increasing physical activity energy expenditure and cardiorespiratory fitness were compared over 12 weeks among inactive adults.Methods: This was an open label, parallel-group RCT. Inactive adults (aged ≥18 years, N=488) were randomized to no intervention (Control; n=121), paper-based diary (Diary; n=124), activity tracker (Activity Band; n=122), or activity tracker plus virtual coaching (Activity Band PLUS; n=121) groups. Coprimary outcomes included 12-week changes in physical activity energy expenditure and fitness (May 2012-January 2014). Analyses were conducted in 2019-2020.Results: There were no differences between groups overall (physical activity energy expenditure: p=0.114, fitness: p=0.417). However, there was a greater increase in physical activity energy expenditure (4.21 kJ/kg/day, 95% CI=0.42, 8.00) in the Activity Band PLUS group than in the Diary group. There were also greater decreases in BMI and body fat percentage in the Activity Band PLUS group than in the Control group (BMI= -0.24 kg/m2, 95% CI= -0.45, -0.03; body fat= -0.48%, 95% CI= -0.88, -0.08) and in theActivity Band PLUS group than in the Diary group (BMI= -0.30 kg/m2, 95% CI= -0.50, -0.09; body fat= -0.57%, 95% CI= -0.97, -0.17).Conclusions: Coupling activity trackers with virtual coaching may facilitate increases in physical activity energy expenditure compared with a traditional paper‒based physical activity diary intervention and improve some secondary outcomes compared with a traditional paper‒based physical activity diary intervention or no intervention.Trial Registration: This study is registered at www.clinicaltrials.gov ISRCTN31844443. [ABSTRACT FROM AUTHOR]

Background: We examined whether a context and process-sensitive 'intelligent' checklist increases compliance with best practice compared with a paper checklist during intensive care ward rounds.Methods: We conducted a single-centre prospective before-and-after mixed-method trial in a 35 bed medical and surgical ICU. Daily ICU ward rounds were observed during two periods of 8 weeks. We compared paper checklists (control) with a dynamic (digital) clinical checklist (DCC, intervention). The primary outcome was compliance with best clinical practice, measured as the percentages of checked items and unchecked critical items. Secondary outcomes included ICU stay and the usability of digital checklists. Data are presented as median (interquartile range).Results: Clinical characteristics and severity of critical illness were similar during both control and intervention periods of study. A total of 36 clinicians visited 197 patients during 352 ward rounds using the paper checklist, compared with 211 patients during 366 ward rounds using the DCC. Per ICU round, a median of 100% of items (94.4-100.0) were completed by DCC, compared with 75.1% (66.7-86.4) by paper checklist (P=0.03). No critical items remained unchecked by the DCC, compared with 15.4% (8.3-27.3) by the paper checklist (P=0.01). The DCC was associated with reduced ICU stay (1 day [1-3]), compared with the paper checklist (2 days [1-4]; P=0.05). Usability of the DCC was judged by clinicians to require further improvement.Conclusions: A digital checklist improved compliance with best clinical practice, compared with a paper checklist, during ward rounds on a mixed ICU.Clinical Trial Registration: NCT03599856. [ABSTRACT FROM AUTHOR]

Consistent evidence has emerged over many years that the mortality and morbidity outcomes for burn patients in low and middle-income countries (LMICs) lag behind those in more resource rich countries. Interburns is a charity that was set up with the aim of working to reduce the disparity in the number of cases of burns as well as the outcomes for patients in LMICs. This paper provides an overview of a cyclical framework for quality improvement in burn care for use in LMICs that has been developed using an iterative process over the last 10 years. Each phase of the process is outlined together with a description of the tools used to conduct a gap analysis within the service, which is then used to frame a programme of capacity enhancement. Recent externally reviewed projects have demonstrated sustained improvement with the use of this comprehensive and integrated approach over a three-year cycle. This overview paper will be supported by further publications that present these results in detail. [ABSTRACT FROM AUTHOR]

The research on knowledge diffusion in the field of intellectual property is growing based on the current research techniques, but it is mostly focused on some of the subfields, such as patent documents and technology transfer. What is lacking in the literature is a comprehensive profile of the discipline. The paper uses bibliometric methods and visualization technologies to conduct a profiling analysis of Web of Science journal articles in the field of intellectual property from the three aspects of authorship network, geographical diffusion of collaboration, and subject cluster. Facilitated by visualization software and programming scripts, the paper presents the highly active scholars in the field through author co-citation analysis (ACA) and document co-citation analysis (DCA), the diffusion networks of collaboration through dynamic geographical graphs, and the five main clusters of disciplinary subjects, namely, Innovation, Judicature, Legislation, Information, and Market. [ABSTRACT FROM AUTHOR]

Background: Accurately identifying patients at an elevated risk of suicide in minimal time is an important mental health issue. Therefore, we developed the Ultra Brief Checklist for Suicidality (UBCS) and reported its psychometric properties.Methods: We studied 544 participants who had completed the UBCS, other self-report measures, and structured clinical interviews by trained interviewers. We explored the psychometric properties of the UBCS's paper-based and online versions by identifying optimal cutoff points, sensitivity, specificity, etc. of all participants.Results: The mean score of the UBCS (paper-pencil version) in the no-suicide-risk group was 0.23 (SD = 0.73), while in the Risk-Positive (RP) and the High-Risk (HR) groups it was 3.54 (SD = 3.22) and 6.31 (SD = 3.97), respectively. Optimal cutoff points for the RP and HR groups were 1 (AUC = 0.914) and 3 (AUC = 0.928), respectively.Limitations: The current findings apply only to adults, not to children or adolescents. The original MINI was used as the assessment instrument's reference standard rather than MINI 7.0.2 of DSM-5. Predictive validity was not addressed as this was not a longitudinal cohort study.Conclusions: The UBCS was rigorously tested and validated. More than half the participants completed the UBCS within a minute. It possesses adequate psychometric properties and can be easily administered with minimal clinician time and effort, via paper or Internet. We believe it can contribute to suicide risk identification and timely interventions. [ABSTRACT FROM AUTHOR]

In this work, we presented a new model called the alpha power inverse power Burr-Hatke distribution (APIPBHD). It provides several greater advantages in fitting a variety of different types of data. Estimates of the model parameters are provided and based on traditional research methods. We established the superiority of the proposed distribution by utilizing the importance and adaptability of the APIPBHD compared to other well-known distributions. The real data set includes 63 observations, all of which were manufactured to approximate the strengths of glass fibers to highlight the relevance and flexibility of the provided technique. We proved our superiority using one set of real data. Finally, major findings and conclusions are recorded at the end of the paper. Also, we added future work on the upcoming research depending on the proposed model. [ABSTRACT FROM AUTHOR]

The NHS England Radiotherapy Service Specification calls for routine use of patient-reported outcome measures (PROMs). However, barriers exist at patient, healthcare professional and service levels. The aim of the present study was to determine the current use of PROMs within radiotherapy services in England. The current attitudes, barriers and enablers to the implementation of PROMs in radiotherapy practice were evaluated and practical recommendations to inform future implementation were developed. A mixed-methods approach was adopted to obtain quantitative and qualitative data. An online questionnaire was developed and disseminated to all radiotherapy operational delivery network managers across England. The questionnaire consisted of 12 open and closed questions relating to PROMs use, with the option to provide free-text responses. Inductive thematic analysis was conducted on free-text comments, whereas descriptive statistics were used to analyse quantitative data. In total, 182 responses were received from 40 of the 50 radiotherapy providers, resulting in a response rate of 84%. The current use of PROMs was analysed, including rationale for use, tools used, format of PROMs collection and timing within the radiotherapy pathway. Most respondents indicated that PROMs were used in the context of clinical trials only. Through thematic analysis, four identical key themes were identified relating to both barriers and enablers to PROMs use; these included IT infrastructure, time, human/financial resources and training/education. A fifth theme, standardisation, was identified as a key enabler to PROMs use. Our findings show that outside of clinical trials, PROMs are not routinely used in radiotherapy services due to barriers identified at professional and service levels. Here we provide recommendations to mitigate the barriers identified and implement PROMs in radiotherapy, including training for healthcare professionals and standardisation of PROMs tools and storage. This study provides a key first step in driving PROMs implementation within radiotherapy services across England. • Outside of clinical trials, PROMs were not widely used within radiotherapy services. • Common PROMs used included QOL, anxiety/depression and urinary/bowel function tools. • PROMs are completed using either paper or electronic forms, by staff or patients. • Barriers include IT infrastructure, time, resources (staff/finances) and training. • Enablers included IT, time, resources, training and standardisation. [ABSTRACT FROM AUTHOR]

Background: Emergency abdominal surgery is associated with poorer clinical outcomes than similar procedures in the elective setting. Research into emergency laparotomy (EL) care is moving from observational studies which simply measure EL outcomes to interventional research evaluating the implementation of care strategies designed to improve the quality and outcomes from EL care. There is no consensus as to the optimal approach to conducting research in this sphere. The primary objective of this review was to examine how mortality and other outcome measures were reported in previous EL research and to identify what might be the most appropriate methods in future outcome research.Methods: A systematic review was performed in accordance with the PRISMA principles. Electronic databases were interrogated with a pre-specified search strategy to identify English language studies addressing outcomes from EL care. Retrieved papers were screened and assessed according to pre-defined eligibility criteria. The mortality and other outcomes reported in each paper were extracted and examined.Results: 16 studies were included. They demonstrated significant heterogeneity in case definition, outcome reporting and data processing. A wide range of mortality and other outcome measures were applied and reported. Only few studies included on patient-reported outcomes measures.Conclusion: The heterogeneity in EL research, demonstrated by this review must be considered when EL outcomes are compared. A standardized approach with respect to case definition, outcome measurement, and data analysis would provide for more valid and comparable evaluation of EL outcomes. Future EL research should include more patient centred outcomes. [ABSTRACT FROM AUTHOR]

Software vulnerabilities are security-related software bugs. Direct disclosure refers to a practice that is widely used for communicating the confidential information about vulnerabilities between two parties, vulnerability discoverers and software producers. Building on software vulnerability life cycle analysis, this empirical paper observes the qualitative and quantitative characteristics of direct disclosure practices, focusing particularly on the historical problem related to producers' reluctance to participate in the practices. According to the results, the problem was still present in the 2000s and early 2010s—and likely is still present today. By presenting this empirical result about the under researched phenomenon of direct disclosure of software vulnerabilities, the paper contributes to the research domain of vulnerability life cycle modeling in general and the subdomain of empirical vulnerability disclosure research in particular. • Direct disclosure refers to a two-party dissemination of vulnerabilities. • Historically many vendors have been reluctant to participate in disclosure. • This paper examines direct disclosure practices in the 2000s and early 2010s. • Both qualitative and quantitative methods are used for the empirical inquiry. • According to the results, the reluctance of vendors has still been widespread. [ABSTRACT FROM AUTHOR]

In order to improve individual research achievements (IRA), this study investigates which affiliated countries and authors earn the most cited IRAs and whether those types of articles are associated with the number of cited papers on schizophrenia from a leading journal in the field. The Kano model was used for displaying the IRAs. Clusters of medical subject headings (MeSH) were applied to explore the core concepts of a given journal. This study aimed to apply social network analysis (SNA) and an authorship-weighted scheme (AWS) to inspect the association between MeSH terms and IRA. About 2,008 abstracts published between 2012 and 2016 in the journal Schizophrenia Research were downloaded from Pubmed Central using the keyword (Schizophr Res)[Journal] on September 20, 2018. The MeSH terms were clustered by using SNA to separate the core concepts and compare the differences in bibliometric indices (i.e., h, Ag, x and author impact factor or AIF). Visual dashboards were shown on Google Maps. Results indicate that (1) the US, the UK, and Canada earn the highest x-index; (2) the top one author from the US has the highest x-index (= 5.73 with x-core at cited = 16.44 and citable = 2); (3) the article type of schizophrenic psychology shows distinctly higher frequencies than others; and (4) article types are associated with the number of cited papers. Four approaches of the Kano model, SNA, MeSH terms, and AWS can be accommodated to display IRAs, classify article types, and quantify coauthor contributions in the article byline, respectively, and applied to other scientific disciplines in the future, not just in this specific journal. [ABSTRACT FROM AUTHOR]

This paper describes and analyses a method of self- and cohort-directed design of research training tutorials for fínal-year research-oriented undergraduate students at the University of Queensland, Australia. The design methodology centered on a research skills self-assessment document used at the university, and utilized Personal Response System (PRS) technology to gather the cohort's design decisions. This paper examines the pedagogical framework for this instructional approach, analyses feedback on the students' experiences and performances, and outlines future further developments for this program. [ABSTRACT FROM AUTHOR]

• Participatory research approaches offer new opportunities for studying mentoring and social capital. • Presents experiences with two user groups: mentoring practitioners and migrant youth (mentees). • Challenges in youth understanding and meaningful engagement. • Challenges in practitioner blending of roles and resource constraints. • Close researcher-practitioner collaboration provided benefits for the mentoring organization, as well as meaningful participation and benefits for a few of the youth. Participatory approaches have gained broad interest among researchers as a vehicle for allowing participants' experiences and voices to inform research, beyond simply being a source of data. However, participants in mentoring programs, particularly young people, often are not included in research partnerships in a meaningful way. Additionally, practitioners often struggle to translate research findings into program improvements. This paper examines the experiences of a research team collaborating with two user groups: mentoring practitioners, and youth with migrant and refugee backgrounds participating in mentoring programs. With ambitions for meaningful user involvement, our aim was to develop and test a digital intervention for supporting social capital in mentoring. The paper draws primarily upon participant observation and qualitative data from a focus group and panel discussions. While youth voices did inform and shape the research, we also experienced challenges related to youth understanding and engagement. The adult practitioners participated actively but encountered tensions due to their dual roles as co-researchers and mentoring professionals, and resource constraints. Ultimately, a close collaboration enabled the co-creation of adaptations to our research approaches, allowing meaningful participation for some of the youth, and facilitating program changes. This paper offers lessons for researchers wishing to conduct participatory research in the context of youth mentoring, as well as specific suggestions for those studying social capital. It contributes to the discussion on participatory approaches with multicultural youth, presenting critical reflections on our experiences within this mentoring context. [ABSTRACT FROM AUTHOR]

• UK law changed in 2018 to permit cannabis prescribing. Cannabis remains otherwise criminalised. Participants experienced benefits from cannabis across a broad range of conditions. • Most people who need a cannabis prescription in the UK still cannot access one. • Poor implementation of cannabis prescribing policy creates heath inequalities. • Intractable prohibition policy context continues to create social harms. This paper reports on the first qualitative study to interview people prescribed cannabis in the UK. Cannabis is a class B controlled substance under the 1971 Misuse of Drugs (MoD) Act, but a 2018 change to UK regulations provided for the prescription of cannabis for medical purposes. Relatively few people have been able to access a prescription, despite this policy change. This paper examines their experiences. Qualitative, semi-structured interviews were conducted with 24 people with a prescription for cannabis, or their carers. Data was analysed using a reflextive thematic analysis approach. The findings are discussed using a zemiology (social harms) perspective which provides a language for critical reflection on the current cannabis policy context. All participants reported that cannabis had significantly improved their mental and/or physical health, across a broad range of conditions. Many had been able to reduce their use of conventional medicines and reported that cannabis had relatively few side effects. Despite the potentially life-enhancing benefits of cannabis medicine, patients in the UK face multiple barriers to access. These include a lack of funding streams, bureaucratic supply problems, and a lack of training for doctors and police. Even for the few people able to obtain a prescription, the ongoing criminalisation of cannabis in the UK contributed to their experiences of stigmatisation. This often made it difficult and anxiety-inducing to take their medicine in public spaces. The UK government's lack of implementation of medical cannabis legalisation, combined with their ongoing prohibition position, is producing multiple harms to people who need cannabis medicine. The policy context is perpetuating stigmatising attitudes to cannabis which, as we demonstrate, contribute to social harms. We make recommendations on equality of patient access, and highlight the importance of education and policy change as means of combatting stigma. [ABSTRACT FROM AUTHOR]

• Young people are rarely included in research & policy that affect their lives. • We conducted youth participatory action research with youth in Cleveland, Ohio. • We show how engaging with youth across all stages of research enriches the work. • Our collaborative research highlights challenges to youth well-being. Research on youth well-being is often driven by adult researcher voices, while youth experiences are neglected. Youth participatory action research (YPAR) is a distinct and powerful approach to capture youth experiences unique to particular social settings and leverage these voices to produce action and change through research. YPAR can be used to challenge oppression, mitigate the researcher-participant hierarchy, and build a social justice-oriented methodology, particularly when it uses a critical and intersectionality lens, rooted in a wider understanding of racial oppression. This methodology paper analyzes our Youth Lens methodology, which uses Critical YPAR to explore African American youth perceptions of how the neighborhood environment shapes health and well-being in Cleveland, Ohio. We describe, in detail, our methodology which was used to examine the history of redlining and systemic racism in the city and how it has driven present-day health and socioeconomic disparities. Further, we reflect in this paper not only on the methodology, but on our own role in the research. We end with implications for collaborative research with youth. [ABSTRACT FROM AUTHOR]

• This paper carries out the research on the evaluation method and system development of emergency regulation capacity for multiple VPPs. • The scientific definition of VPP emergency regulation capacity is clarified, the evaluation method of VPP emergency regulation capacity is proposed, and the evaluation model for the regulation capacity of different types of DER is established. • The framework of multiple management and control for VPP is proposed, which coves intelligent terminal layer sensing DER status, VPP control center integrating heterogeneous DER, and VPP cloud control platform collaborative dispatching multiple VPPs. • The VPP modular model is built, the general simulation architecture and open interface design are realized, and the simulation system for VPP participation in power grid emergency dispatching is developed. The penetration rate of decentralized and controllable resources on the demand side is gradually increasing, such as renewable energy power generation, electricity storage device, electric vehicle, and temperature controlled load. It is urgent to upgrade the security architecture of power grid and incorporate decentralized and controllable resources into the scope of power grid emergency dispatching. Virtual power plant (VPP) is an effective form of integration and management for massive distributed energy resources (DERs), and system development is an important support to play its role. Aiming at the demand of power grid emergency dispatching, this paper proposes the research on the evaluation method and system development of emergency regulation capacity for multiple VPPs. The connotation of VPP emergency regulation capacity is first elucidated, and its quantitative evaluation method is proposed. Then, considering the physical characteristic and user behavior of DER, the evaluation model of emergency regulation capacity of DER cluster is constructed. On this basis, the framework of multilayer management and control for VPP is designed, and the calculation program of VPP emergency regulation capacity is developed. Through modular modeling and the design of general architecture and open interactive interface, a simulation system for VPP participating in power grid emergency dispatching is developed. Finally, a single VPP containing heterogeneous DERs is taken as an example to illustrate the simulation results and sensitivity analysis of VPP emergency regulation capacity. Taking the regional power grid with multiple VPPs as an example, the supporting effect of VPP on power grid emergency dispatching is illustrated. The simulation results verify the effectiveness of the proposed method and system development. [ABSTRACT FROM AUTHOR]

• The increasing complexity of modern aircraft structures and the use of new fuels and materials have amplified the complexity of aircraft fire incidents. • Study and discuss the latest research findings in the field of aircraft fires, including aircraft-specific fire behavior, aircraft materials, and aircraft ignition. • Discusses the available aircraft fire investigation methods and the scientific aircraft fire investigation process. • Analysis of important typical aircraft fire accidents in recent years. Fires frequently contribute to aircraft accidents, leading to significant damage, injuries, and fatalities. Nevertheless, the increasing complexity of modern large aircraft structures, along with the utilization of new aviation fuels and materials, has further complicated aircraft fire accidents. Therefore, the application of scientific methodologies and technological advancements is crucial for investigating and determining the causes of aircraft fires. This paper analyzes and discusses various techniques employed in the investigation of aircraft fires, encompassing fire behavior characterization, analysis of aviation material debris, and evaluation of ignition energy. Additionally, it presents an overview and comprehensive discussion of the scientific investigation process employed in aircraft fire incidents. Lastly, this paper presents recent case studies of typical aircraft fires, including crash fires, engine fires, electrical failures, equipment failures, and fires caused by external sources. This study has three overarching themes. The study provides a comprehensive review of the current research on aircraft fire-related issues while highlighting the investigation process and scientific analysis methods employed in aircraft fire incidents. Case studies demonstrate technical investigations of typical aircraft fire incidents are provided. These cases exemplify the complexity involved in aircraft fire investigations and emphasize the criticality of analyzing failure particulars in understanding fire incidents. This paper promote the advancement of technical investigations of aircraft fire incidents by advocating for the updating of research findings and investigation practices related to aircraft fires. [ABSTRACT FROM AUTHOR]

The Shenlian formula (SL) is a Chinese medicine formula used to curb the development of atherosclerosis (AS) and cardiovascular disease in clinical practice. However, owing to the complexity of compounds and their related multiple targets in traditional Chinese medicine (TCM), it remains difficult and urgent to elucidate the underlying mechanisms at a holistic level. To investigate the intrinsic mechanisms by which SL suppresses AS progression and to gain new insight into its clinical use. We proposed a network pharmacology-based workflow to evaluate the mechanism by which SL affects AS via data analysis, target prediction, PPI network construction, GO and KEGG analyses, and a "drug-core ingredient-potential target-key pathway" network. Then, non-targeted lipidomic analysis was performed to explore the differential lipid metabolites in AS rats, revealing the possible mechanism by which SL affects atherosclerotic progression. Moreover, an AS rabbit model was constructed and gavaged for SL intervention. Serum lipid profiles and inflammatory cytokine indices were tested as an indication of the mitigating effect of SL on AS. A total of 89 bioactive compounds and 298 targets related to SL and AS, which play essential roles in this process, were identified, and a component-target-disease network was constructed. GO and KEGG analyses revealed that SL regulated metabolic pathway, lipids and atherosclerosis, the PI3K-Akt pathway, the MAPK pathway and so on. In vivo experimental validation revealed that a total of 43 different lipid metabolites regulated by SL were identified by non-targeted lipidomics, and glycerophospholipid metabolism was found to be an important mechanism for SL to interfere with AS. SL reduced the plaque area and decreased the levels of inflammatory cytokines (TNF-α and IL-4) and blood lipids (TC, TG, LDL-C, and ApoB) in HFD-induced AS models. In addition, HDL and ApoA 1 levels are increased. PLA2 and Lipin1 are highly expressed in AS model, indicating their role in destabilizing glycerophosphatidylcholine metabolism and contributing to the onset and progression of ankylosing spondylitis. Moreover, SL intervention significantly reduced the level of pro-inflammatory cytokines; significantly down-regulated NF-kB/p65 expression, exhibiting anti-inflammatory activity. The Shenlian formula (SL) plays a pivotal role in the suppression of AS progression by targeting multiple pathways and mechanisms. This study provides novel insights into the essential genes and pathways associated with the prognosis and pathogenesis of AS. [Display omitted] • The innovation of this paper lies in clarifying the therapeutic effect of SL on atherosclerosis, especially the prediction of anti-atherosclerosis active ingredients and related targets by network pharmacology tools. • The network pharmacology prediction and lipid metabolism pathway were verified by In vivo experiments, in atherosclerosis model. • SL formula intervention significantly reduced the level of pro-inflammatory cytokines; significantly down-regulated NF-kB/p65 expression, exhibiting anti-inflammatory activity. [ABSTRACT FROM AUTHOR]

Collaborative work processes from the perspective of Building Information Modeling demand technical and organizational information requirements from managers. In response, data schema Industry Foundation Classes (IFC) has been making significant entities and domain inclusions with a semantic level capable of supporting OpenBIM interoperability throughout the project lifecycle. This paper applies Design Science Research methodology to explore how the IFC should be specified so that BIM actors can meet the representation context of a project translating data through Inheritance Diagrams, which offer auxiliary contributions. The Protocol developed to address the research problem revealed that some information requirements had not been met, as the universe of optional data in the schema is broad. Therefore, an artifact is created to fully meet the demand and is validated by different software. This reveals that the insertion of data can be performed to meet the desired interoperability and stands a valuable tool for BIM actors. • IfcProject specifies 3 main frameworks: Identification; Financial; Geometric and Unit • The mapping of potentially semantic data aimed at specifying Project representation • The 3D tree presents the logic in which IFC data architecture was conceived • Inheritance diagrams help clarify the theoretical foundation of the IFC schema • Graphs represent mechanisms capable of assisting humans in understanding the SPF file [ABSTRACT FROM AUTHOR]

• Application of Finite-Element-Method for calculation of cable parameters. • Accurate geometric modeling is advised when using Finite-Element-Method. • Improvement of analytical equations for the calculation of cable capacitances. • Considering capacitances for impedance studies is advised for higher frequencies. • Impact of parameter uncertainty on impedance is discussed and quantified. Recent research presented methods to improve the calculation of low voltage cable parameters by using finite-element models due to increasing focus on power quality issues in distribution grids. However, the focus was mostly on series parameters and nominal frequency. In this paper the calculation of cable capacitances as well as their impact on harmonic impedance of a single cable and in a rural low voltage grid is discussed using detailed finite-element models. Moreover, the accuracy of geometric simplification was quantified. The results are used to compare and optimize existing analytical equations. Furthermore, sources of uncertainty in cable modeling were identified and their range of impact on impedance was subsequently studied to give recommendations regarding necessary study cases for a robust assessment of grid impedance. [ABSTRACT FROM AUTHOR]

Social science research on polio has been centred in the global south, where countries that remain endemic or vulnerable to outbreaks are located. However, closely-related strains of poliovirus were detected in the sewage systems of several New York State counties and London boroughs in 2022. These detections constituted the first encounters with polio in the United States and United Kingdom for a generation – for both public health agencies and publics alike. This paper takes the transnational spread of poliovirus in 2022 as an opportunity to critique how public health memories of twentieth-century polio epidemics were mobilised to encourage vaccine uptake among groups considered vulnerable to transmission, notably Orthodox Jewish families. The study integrates data collected in London and New York as part of academic engagement with health protection responses to the spread of polio. Methods in both settings involved ethnographic research, and a total of 59 in-depth semi-structured interviews with public health professionals, healthcare providers, and Orthodox Jewish community partners and residents. Analysis of results demonstrate that narratives of epidemiological progress were deployed in public health responses in London and New York, often through references to sugar cubes, iron lungs, and timelines that narrate the impact of routine childhood immunisations. While memories of polio were deployed in both settings to provoke an urgency to vaccinate, vulnerable publics instead considered the more recent legacy of the COVID-19 pandemic when deciding whether to trust recommendations and responses. Critical attention to memory places analysis on the divergences between institutional (public health agencies) and peopled (publics) responses to disease events. Responses to re-emerging infectious disease outbreaks engender a temporal dissonance when historical narratives are evoked in ways that contrast with the contemporary dilemmas of people and parents. • Memories of past polio outbreaks were deployed to encourage vaccination in 2022. • Vulnerable publics were instead concerned with the legacy of Covid-19 mis/management. • Memory provokes diverging concerns for public health agencies and communities. • Learning from community experiences of outbreaks may inform engagement strategies. [ABSTRACT FROM AUTHOR]

This paper investigates how healthcare professionals experience digital platforms in their work practices and how these relationships enable forms of emotional labour and contribute to shaping their emotional health. Methodologically, the contribution draws on audio-diaries kept by 15 healthcare professionals and a final semi-structured interview conducted with the same informants. The research material was analysed using open and axial coding techniques, in a grounded theory fashion. Findings provides meaningful insights to the literature on the emotional labour of healthcare professionals, as well as to studies on digital health and labour. Specifically, we show that participants associate different and even contrasting reflections and emotional states with their relationships with digital platforms. Thus, there is not exclusively one trajectory that can explain the implications of media uses, as different and potentially conflicting emotions coexist within the same experience. Given this scenario, we argue that it can be fruitful to use the lens of 'ambiguity' to scrutinise the ambivalences and tensions characterising platform experiences, and how emotional labour in healthcare intertwines with technological developments. Moreover, we advocate for the development of critical digital literacy skills among healthcare professionals. • We contribute to literature on digital health and emotional labour. • We show the emotional ambivalences in healthcare professionals' platform experiences. • We argue for the merits of using the concept of 'ambiguity'. • We advocate for critical digital literacy among healthcare professionals. [ABSTRACT FROM AUTHOR]

In environments with high humidity or water exposure, the performance of polyurethane materials could be adversely affected by water and its penetration, which could compromise their long-term utility. The influence of water on polyurethane materials is affected by water transport and various factors. This article summarizes the factors affecting the water absorption of polyurethane, introduces research methods for water transport in polyurethane, analyzes the pathways of water transport, and reviews the influence of water on the mechanical properties of polyurethane and its composite materials. The ultimate goal of this paper is to furnish a comprehensive theoretical foundation and a valuable reference for the research and practical application of polyurethane materials in water environments. [Display omitted] • Polyurethane water absorption is influenced by multiple factors. • Summarized the research methods for water transport in polyurethane. • Analyzed the pathways of water transport in polyurethane. • Water significantly affects the mechanical properties of polyurethane. [ABSTRACT FROM AUTHOR]

The image of a place is subjective and open to change: it depends on an individual's perspective and cultural background. Notwithstanding years of research on destination image, no attempt has been made so far to evaluate the Muslim-Friendly Tourist Destination Image (MFTDI) in the travel and hospitality industry, in which Muslim visitors not only evaluate cognitive and emotional attributes but also Muslim-friendly attributes. In this research a qualitative research and literature review was carried out to develop the items of the proposed scale. The study began with a pilot study in which a committee of experts, and focus groups reduced the topic quantitatively and qualitatively. A follow-up quantitative assessment was then carried out to evaluate and authenticate the suggested scale, using two studies (n1 = 481 and n2 = 269). The significance of the proposed scale was conceptually justified. The scale measured reliability, discriminant validity, convergent validity, and external validity. As a result, the outcomes suggest that the 31 items to be considered fall into three factor categories: cognitive, emotional, and Muslim-friendly qualities. Finally, this paper assesses the article's significant implications for theory and practice, as well as its limitations. • Limited research on the destination image from an Islamic perspective. • This study aims to develop a new MFTDI construct and its dimensions. • Measuring MFTDI requires considering Muslim-friendly attributes. [ABSTRACT FROM AUTHOR]

According to popular understandings, children grow from a state of dependence to eventually become independent adults. Interdependence helps to disrupt the in/dependence binary and is a useful concept for making sense of the experiences young people with variations in sex characteristics in relation to healthcare. This study used semi-structured interviews with 32 health professionals, 33 caregivers and 12 young people recruited in the UK and Sweden. The analysis is guided by the questions: (1) how do young people, carers and health professionals position themselves in the adult/young person relationship in the context of healthcare? (2) how is the (in/ter)dependence of young people imagined when young people, carers and health professionals talk about healthcare? Our analysis shows how carers and health professionals might support dominant understandings about young people growing towards independence while providing little opportunity for young people's agency and voice. Interviews with young people gave clear examples of their negotiating relational ways of being, seeking agency in the context of healthcare and not simply becoming independent of adults. This analysis also draws attention to the ways young people might be silenced within healthcare contexts. The present paper is based on secondary analysis of data from the SENS. It works with concepts of relationality and interdependence to draw out the possibilities of voice and agency for young people with variations in sex characteristics in healthcare contexts. • Youth with variations in sex characteristics are sometimes silenced in the clinic. • There is sometimes too little room for youth agency in healthcare. • A relational approach could improve the healthcare experiences of young people. • Working towards interdependence, not simply independence, can support youth. • It is important to value knowledge that is based on intersex lived experience. [ABSTRACT FROM AUTHOR]

• In a bid to resist a medical-moralist paradigm dominating public health ideologies, we make a case for understanding chemsex among men in Singapore vis-à-vis Deleuzean lines of flight. • Through a queer deleuzean framing, we illustrate how chemically inflected sexual encounters can offer deterritorialising flights of fantasy and freedom from a heteronormative social structure that stigmatises gay sex, among other normative regimes. • We explored how lines of flight generated by chemsex are dynamic (i.e. they can turn into lines of non-flight) and have to be unpacked contextually (i.e. in relation to unfolding senses of self and the social environment). We have also demonstrated that such deterritorialising flights of freedom can catalyse unplanned outcomes, including the propensity to reterritorialise. • Our analysis has not shied away from incorporating heartfelt anecdotes that perpetuate medico-moral, public health perspectives even as we are committed to a critical-political discussion on chemical-sexual intimacies. • Future research in this arena could potentially investigate the complicated, conflicted and protracted intimate relationships that users may have with their drug(s) of choice, as well as the varied lines of (non-)flight that these chemicals can endow over a longitudinal study. Public health scholars informed by a dominant biomedical paradigm have in their 'rush to risk' emphasised the problematic aspects of chemsex. Meanwhile, critical chemsex scholars have attemped to destigmatise such sexual-chemical practices and foreground how they can be transformative. Taking these two perspectives as points of departure, we make a case for understanding chemsex vis-à-vis Deleuzean lines of flight. Semi-structured in-depth interviews were conducted with 33 purposively sampled sexual minority men seeking therapy for chemsex dependency in Singapore. Interview topics included participants' experiences and histories of chemsex, substance use, and their ongoing recovery. Interviews were audio-recorded, transcribed and then analysed according to key themes. We illustrate how chemically inflected sexual encounters can offer deterritorialising flights of fantasy and freedom from a heteronormative social structure that pathologises gay sex. At the same time, we argue that these flight lines are not static, neither do they extend indefinitely in space-time. Rather, we show how flights of freedom can evolve into lines of fright (or non-flight) when chemsex practitioners are met with critical thresholds that reveal the less-than-desirable aspects of being intoxicated. Consequently, they may eventually consider the reterritorialisation of their lives (i.e. abstinence and recovery) as a more constructive option. Regardless of their decisions to ride on chemically-induced flight lines or to take a step back from such deterritorialising pathways, they have troubled stereotypical perspectives of drug users as passive automatons. This paper enriches the chemsex scholarship by presenting a Deleuzean conceptualisation of chemical-sexual intimacies without romantacising and/or overstating the 'escape'/'freedom' that chemsex can facilitate. Future research in this arena could explore the complicated intimate relationships that users may have with their drug(s) of choice, and their varied lines of (non-)flight over a longitudinal study. [ABSTRACT FROM AUTHOR]

The factors that inhibit and promote professional interventions with young adults refer to social, formal-structural, and personal factors. Nevertheless, studies of these factors from social workers' perspective, and research of the inhibitors associated with the socio-cultural context of minority young adults, are few. The aim of the present study was to examine social workers' perceptions of the factors that inhibit and promote interventions in the socio-cultural and formal-structural context of at-risk young Arab-Palestinian women in Israel, who are at an intersection of marginal positions. Semi-structured in-depth interviews were conducted with 21 social workers. The findings revealed two themes: 1) Social workers' perceptions of the challenges in two dimensions, a) socio-cultural factors which include family centrality in the young women's life, and b) formal-structural inhibitors. 2) Promoting factors which include professional values and the need for cooperation between organizations themselves and with recipients of the services The findings were reviewed according to the intersectional invisibility model, and were based on the concept of institutional discrimination, which showed that at-risk young Arab women experience an intersectional invisibility of their identities and, at the same time, the social workers experience a conflicting situation within the wider context of intersectional discrimination. The paper concludes with recommendations to practitioners and policymakers. [ABSTRACT FROM AUTHOR]