Search

Your search keyword '"Ahn, Song Ih"' showing total 2 results
Start Over Author "Ahn, Song Ih" Publisher elsevier b.v.
2 results on '"Ahn, Song Ih"'

1. Human Blood–Brain Barrier on a Chip: Featuring Unique Multicellular Cooperation in Pathophysiology.

Author

Ahn, Song Ih and Kim, YongTae

Subjects
*BLOOD-brain barrier, *PATHOLOGICAL physiology, *STEM cells, *HUMAN beings, *COOPERATION
Abstract

Advances in stem cell engineering have opened new avenues for more accurately developing in vitro models of the human blood–brain barrier (BBB). Here, we highlight state-of-the-art human BBB-on-a-chip technologies and discuss the importance of human brain cells for better modeling the human brain pathophysiology. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

2. Nanotherapeutics engineered to cross the blood-brain barrier for advanced drug delivery to the central nervous system.

Author

Kim, Jinhwan, Ahn, Song Ih, and Kim, YongTae

Subjects
BLOOD-brain barrier, CENTRAL nervous system, BRAIN diseases, BIOMEDICAL engineering, NANOMEDICINE, BRAIN
Abstract

Graphical abstract Abstract Drug delivery to the brain remains challenging mainly due to the blood-brain barrier (BBB) that regulates the entrance of substances to the brain. Advances in nanotechnology have enabled the engineering of nanomedicines for biomedical applications including enhanced drug delivery into the brain. In this review, we describe strategies of nanomedicines engineered to traverse the BBB and deliver therapeutic molecules to target brain sites. We highlight the representative applications with materials including polymers, lipids, and inorganic elements for brain drug delivery. We finalize this review with the current challenges and future perspective of nanotherapeutics for advanced drug delivery to the brain. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results