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Cardiovascular disease (CVD) is the leading cause of death among non-communicable diseases in Cameroon. Methods A cost-utility analysis of three population salt reduction interventions: school-based salt education program, mass media campaign, and low-sodium salt substitute was conducted using a multi-state lifetable Markov model. Results For the remaining lifetime, over 10,000 CVD deaths, 79,000 CVD deaths and 84,000 CVD deaths could be averted from the mass media, school education program and salt substitute interventions respectively. [Extracted from the article]