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Start Over Author "Bracco L" Publisher elsevier b.v.
13 results on '"Bracco L"'

12. 137. rTMS in the Primary Progressive Aphasia: Two case-reports taken from open study treatment protocol.

Author

Carrai, R., Padiglioni, S., Angelini, A., Vettori, A., Atzori, T., Bessi, V., Bracco, L., Pizzi, A., and Grippo, A.

Subjects
*APHASIA, *MEDICAL protocols, *TRANSCRANIAL magnetic stimulation, *NEURODEGENERATION, *LEXICAL access, *PATIENT safety, *THERAPEUTICS
Abstract

Repetitive transcranial magnetic stimulation (rTMS) improved action naming in subjects with aphasia in neurodegenerative disorders in a single session. We decided to investigate possible utility of rTMS in a rehabilitation setting in addition as to logopedic treatment. Consecutive patients affected by Progressive Primary Aphasia (PPA)—nonfluent type, were underware to a cycle of 3weeks of high frequency rTMS of dorsolateral prefrontal cortex (DLPFC) and logopedic treatments. The patients’ performance was evaluated on a battery of language (Italian version of AAT), before and after treatments. We evaluated two subjects. First showed a significant improvement of patient’s performance in subtest “denomination”; a slight increase in “written language” and fewer number of error in “Token Test”. The second with severe disease discontinued treatment after 8days for the occurrence of adverse events. The finding in mild disease patient suggests that rTMS of DLPFC may strengthen the neural connections within an area of metabolic dysfunction with a facilitation effect on lexical retrieval processes. According to our experience, the rTMS may not be indicated, for the safety of patient, in advanced and severe stages of disease. A Randomized Control Trial is needed to verify the utility of rTMS for neurodegenerative forms of aphasia. [Copyright &y& Elsevier]

Published
2013
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