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Your search keyword '"Cai Z."' showing total 193 results
Start Over Author "Cai Z." Publisher elsevier b.v.
193 results on '"Cai Z."'

1. Japan Trench event stratigraphy: First results from IODP giant piston coring in a deep-sea trench to advance subduction zone paleoseismology

Author

Everest, J., Maeda, L., Hochmuth, K., Grant, H., Stewart, M., Okutsu, N., Sakurai, N., Yokoyama, T., Bao, R., Bellanova, P., Brunet, M., Cai, Z., Cattaneo, A., Hsiung, K.H., Huang, J.-J.S., Ishizawa, T., Jitsuno, K., Johnson, J.E., Kanamatsu, T., Keep, M., Kölling, M., Luo, M., März, C., Micallef, A., Nagahashi, Y., Pandey, D., Rasbury, T., Riedinger, N., Seibert, C., Silver, M., Straub, S., Virtasalo, J.J., Wang, Y.H., Wu, T.-W., Zellers, S.D., Strasser, Michael, Ikehara, Ken, Pizer, Charlotte, Itaki, Takuya, Satoguchi, Yasufumi, Kioka, Arata, McHugh, Cecilia, Proust, Jean-Noel, and Sawyer, Derek

Published
2024
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7. Effects of personalized oral exercises on swallowing function among patients with oral cancer after free flap transplantation: a cluster randomized controlled trial.

Author

Zhang, J., Wu, H.-Y., Shan, X.-F., Cai, Z.-G., Zhang, L., and Yang, Y.

Subjects
CLUSTER randomized controlled trials, VIDEOFLUOROSCOPY, FREE flaps, ORAL cancer, CANCER patients, DEGLUTITION
Abstract

Dysphagia is a common complication in patients with oral cancer who have undergone free flap transplantation. The aim of this cluster randomized controlled trial was to evaluate the effect of personalized oral exercises on swallowing function in this group of patients. Eligible patients were randomly assigned to the intervention (n = 34) or control (n = 34) group. Intervention group patients received personalized oral exercises starting on day 6 after surgery. Swallowing function was evaluated on days 6 and 15, and at 1 month postoperative using the Mann Assessment of Swallowing Ability–Oral Cancer tool (MASA-OC). On day 15 and at 1 month after surgery, the total MASA-OC score (P = 0.003, P < 0.001) and the mouth opening (P = 0.001, P < 0.001) and lip seal (both P < 0.001) item scores showed a significantly greater improvement in the intervention group than in the control group. Moreover, the changes in salivation (P < 0.001) and tongue movement (P = 0.025) scores at 1 month after surgery were significantly greater in the intervention group than in the control group. There was no significant difference between the groups in the change in tongue strength scores on day 15 or at 1 month postoperative (P = 0.476, P = 0.223). Personalized oral exercises can improve swallowing function in patients with oral cancer after free flap transplantation. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Intraosseous schwannoma of the mandible: new case series, literature update, and proposal of a classification.

Author

Li, S., Wang, Z., Li, Z., Xie, S., Shan, X., and Cai, Z.

Subjects
MANDIBLE, MANDIBULAR nerve, SCHWANNOMAS, CEREBRAL cortical thinning
Abstract

Intraosseous schwannoma of the mandible is rare, with diagnostic and therapeutic challenges. The aims of this study were to report new cases of intraosseous schwannoma of the mandible and to propose a clinical classification, providing suggestions for treatment methods. The cases of 13 patients treated at the authors' hospital and 86 cases reported previously in the literature were reviewed. The most common clinical feature was facial swelling (60/93). The rate of cortical thinning or expansion was 44.8% (43/96); widening of the inferior alveolar nerve canal on radiographs was observed in 15 patients. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Invited review: Good practices in genome-wide association studies to identify candidate sequence variants in dairy cattle.

Author

Sahana, G., Cai, Z., Sanchez, M.P., Bouwman, A.C., and Boichard, D.

Subjects
*DAIRY cattle, *GENOME-wide association studies, *QUALITY control, *LINKAGE disequilibrium, *GENE mapping, *BEST practices
Abstract

Genotype data from dairy cattle selection programs have greatly facilitated GWAS to identify variants related to economic traits. Results can enhance the accuracy of genomic prediction, analyze more complex models that go beyond additive effects, elucidate the genetic architecture of a trait, and finally, decipher the underlying biology of traits. The entire process, comprising data generation, quality control, statistical analyses, interpretation of association results, and linking results to biology should be designed and executed to minimize the generation of false-positive and false-negative associations and misleading links to biological processes. This review aims to provide general guidelines for data analysis that address data quality control, association tests, adjustment for population stratification, and significance evaluation to improve the reliability of conclusions. We also provide guidance on post-GWAS strategy and the interpretation of results. These guidelines are tailored to dairy cattle, which are characterized by long-range linkage disequilibrium, large half-sib families, and routinely collected phenotypes, requiring different approaches than those applied in human GWAS. We discuss common limitations and challenges that have been overlooked in the analysis and interpretation of GWAS to identify candidate sequence variants in dairy cattle. [ABSTRACT FROM AUTHOR]

Published
2023
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11. Optimization of the JUNO liquid scintillator composition using a Daya Bay antineutrino detector

Author

Abusleme, A, Adam, T, Ahmad, S, Aiello, S, Akram, M, Ali, N, An, F, An, G, An, Q, Andronico, G, Anfimov, N, Antonelli, V, Antoshkina, T, Asavapibhop, B, de Andre, J, Babic, A, Balantekin, A, Baldini, W, Baldoncini, M, Band, H, Barresi, A, Baussan, E, Bellato, M, Bernieri, E, Biare, D, Birkenfeld, T, Bishai, M, Blin, S, Blum, D, Blyth, S, Bordereau, C, Brigatti, A, Brugnera, R, Budano, A, Burgbacher, P, Buscemi, M, Bussino, S, Busto, J, Butorov, I, Cabrera, A, Cai, H, Cai, X, Cai, Y, Cai, Z, Cammi, A, Campeny, A, Cao, C, Cao, G, Cao, J, Caruso, R, Cerna, C, Chang, J, Chang, Y, Chen, H, Chen, P, Chen, S, Chen, X, Chen, Y, Chen, Z, Cheng, J, Cheng, Y, Cheng, Z, Chepurnov, A, Cherwinka, J, Chiarello, F, Chiesa, D, Chimenti, P, Chu, M, Chukanov, A, Chuvashova, A, Clementi, C, Clerbaux, B, Di Lorenzo, S, Corti, D, Costa, S, Dal Corso, F, Cummings, J, Dalager, O, De La Taille, C, Deng, F, Deng, J, Deng, Z, Depnering, W, Diaz, M, Ding, X, Ding, Y, Dirgantara, B, Dmitrievsky, S, Diwan, M, Dohnal, T, Donchenko, G, Dong, J, Dornic, D, Doroshkevich, E, Dove, J, Dracos, M, Druillole, F, Du, S, Dusini, S, Dvorak, M, Dwyer, D, Enqvist, T, Enzmann, H, Fabbri, A, Fajt, L, Fan, D, Fan, L, Fang, C, Fang, J, Fatkina, A, Fedoseev, D, Fekete, V, Feng, L, Feng, Q, Fiorentini, G, Ford, R, Formozov, A, Fournier, A, Franke, S, Gallo, J, Gan, H, Gao, F, Garfagnini, A, Gottel, A, Genster, C, Giammarchi, M, Giaz, A, Giudice, N, Giuliani, F, Gonchar, M, Gong, G, Gong, H, Gorchakov, O, Gornushkin, Y, Grassi, M, Grewing, C, Gromov, M, Gromov, V, Gu, M, Gu, W, Gu, X, Gu, Y, Guan, M, Guardone, N, Gul, M, Guo, C, Guo, J, Guo, L, Guo, W, Guo, X, Guo, Y, Guo, Z, Haacke, M, Hackenburg, R, Hackspacher, P, Hagner, C, Han, R, Han, Y, Hans, S, He, M, He, W, Heeger, K, Heinz, T, Heng, Y, Herrera, R, Higuera, A, Hong, D, Hor, Y, Hou, S, Hsiung, Y, Hu, B, Hu, H, Hu, J, Hu, S, Hu, T, Hu, Z, Huang, C, Huang, G, Huang, H, Huang, Q, Huang, W, Huang, X, Huang, Y, Huber, P, Hui, J, Huo, L, Huo, W, Huss, C, Hussain, S, Insolia, A, Ioannisian, A, Ioannisyan, D, Isocrate, R, Jaffe, D, Jen, K, Ji, X, Jia, H, Jia, J, Jian, S, Jiang, D, Jiang, X, Jin, R, Jing, X, Johnson, R, Jollet, C, Jones, D, Joutsenvaara, J, Jungthawan, S, Kalousis, L, Kampmann, P, Kang, L, Karagounis, M, Kazarian, N, Kettell, S, Khan, A, Khan, W, Khosonthongkee, K, Kinz, P, Kohn, S, Korablev, D, Kouzakov, K, Kramer, M, Krasnoperov, A, Krokhaleva, S, Krumshteyn, Z, Kruth, A, Kutovskiy, N, Kuusiniemi, P, Lachacinski, B, Lachenmaier, T, Landini, C, Langford, T, Lee, J, Lefevre, F, Lei, L, Lei, R, Leitner, R, Leung, J, Li, D, Li, F, Li, H, Li, J, Li, K, Li, M, Li, N, Li, Q, Li, R, Li, S, Li, T, Li, W, Li, X, Li, Y, Li, Z, Liang, H, Liang, J, Liebau, D, Limphirat, A, Limpijumnong, S, Lin, C, Lin, G, Lin, S, Lin, T, Lin, Y, Ling, J, Link, J, Lippi, I, Littenberg, L, Littlejohn, B, Liu, F, Liu, H, Liu, J, Liu, M, Liu, Q, Liu, R, Liu, S, Liu, X, Liu, Y, Lokhov, A, Lombardi, P, Loo, K, Lorenz, S, Lu, C, Lu, H, Lu, J, Lu, S, Lu, X, Lubsandorzhiev, B, Lubsandorzhiev, S, Ludhova, L, Luk, K, Luo, F, Luo, G, Luo, P, Luo, S, Luo, W, Lyashuk, V, Ma, Q, Ma, S, Ma, X, Ma, Y, Malyshkin, Y, Mantovani, F, Mao, Y, Mari, S, Marini, F, Marium, S, Marshall, C, Martellini, C, Martin-Chassard, G, Caicedo, D, Martini, A, Martino, J, Mayilyan, D, Mcdonald, K, Mckeown, R, Muller, A, Meng, G, Mednieks, I, Meng, Y, Meregaglia, A, Meroni, E, Meyhofer, D, Mezzetto, M, Miller, J, Miramonti, L, Monforte, S, Montini, P, Montuschi, M, Morozov, N, Muralidharan, P, Napolitano, J, Nastasi, M, Naumov, D, Naumova, E, Nemchenok, I, Nikolaev, A, Ning, F, Ning, Z, Nunokawa, H, Oberauer, L, Ochoa-Ricoux, J, Olshevskiy, A, Ortica, F, Pan, H, Paoloni, A, Park, J, Parkalian, N, Parmeggiano, S, Patton, S, Payupol, T, Pec, V, Pedretti, D, Pei, Y, Pelliccia, N, Peng, A, Peng, H, Peng, J, Perrot, F, Petitjean, P, Rico, L, Popov, A, Poussot, P, Pratumwan, W, Previtali, E, Pun, C, Qi, F, Qi, M, Qian, S, Qian, X, Qiao, H, Qin, Z, Qiu, S, Rajput, M, Ranucci, G, Raper, N, Re, A, Rebber, H, Rebii, A, Ren, B, Ren, J, Reveco, C, Rezinko, T, Ricci, B, Robens, M, Roche, M, Rodphai, N, Rohwer, L, Romani, A, Rosero, R, Roskovec, B, Roth, C, Ruan, X, Rujirawat, S, Rybnikov, A, Sadovsky, A, Saggese, P, Salamanna, G, Sangka, A, Sanguansak, N, Sawangwit, U, Sawatzki, J, Sawy, F, Schever, M, Schuler, J, Schwab, C, Schweizer, K, Selivanov, D, Selyunin, A, Serafini, A, Settanta, G, Settimo, M, Shahzad, M, Shi, G, Shi, J, Shi, Y, Shutov, V, Sidorenkov, A, Simkovic, F, Sirignano, C, Siripak, J, Sisti, M, Slupecki, M, Smirnov, M, Smirnov, O, Sogo-Bezerra, T, Songwadhana, J, Soonthornthum, B, Sotnikov, A, Sramek, O, Sreethawong, W, Stahl, A, Stanco, L, Stankevich, K, Stefanik, D, Steiger, H, Steiner, H, Steinmann, J, Stender, M, Strati, V, Studenikin, A, Sun, G, Sun, L, Sun, J, Sun, S, Sun, X, Sun, Y, Suwonjandee, N, Szelezniak, M, Tang, J, Tang, Q, Tang, X, Tietzsch, A, Tkachev, I, Tmej, T, Treskov, K, Troni, G, Trzaska, W, Tse, W, Tull, C, Tuve, C, van Waasen, S, Boom, J, Vassilopoulos, N, Vedin, V, Verde, G, Vialkov, M, Viaud, B, Viren, B, Volpe, C, Vorobel, V, Votano, L, Walker, P, Wang, C, Wang, E, Wang, G, Wang, J, Wang, K, Wang, L, Wang, M, Wang, N, Wang, R, Wang, S, Wang, W, Wang, X, Wang, Y, Wang, Z, Watcharangkool, A, Wei, H, Wei, L, Wei, W, Wei, Y, Wen, L, Whisnant, K, White, C, Wiebusch, C, Wong, S, Wong, H, Wonsak, B, Worcester, E, Wu, C, Wu, D, Wu, F, Wu, Q, Wu, W, Wu, Z, Wurm, M, Wurtz, J, Wysotzki, C, Xi, Y, Xia, D, Xie, Y, Xie, Z, Xing, Z, Xu, D, Xu, F, Xu, H, Xu, J, Xu, M, Xu, T, Xu, Y, Xue, T, Yan, B, Yan, X, Yan, Y, Yang, A, Yang, C, Yang, H, Yang, J, Yang, L, Yang, X, Yang, Y, Yao, H, Yasin, Z, Ye, J, Ye, M, Yegin, U, Yeh, M, Yermia, F, Yi, P, You, Z, Young, B, Yu, B, Yu, C, Yu, H, Yu, M, Yu, X, Yu, Z, Yuan, C, Yuan, Y, Yuan, Z, Yue, B, Zafar, N, Zambanini, A, Zeng, P, Zeng, S, Zeng, T, Zeng, Y, Zhan, L, Zhang, C, Zhang, F, Zhang, G, Zhang, H, Zhang, J, Zhang, P, Zhang, Q, Zhang, T, Zhang, X, Zhang, Y, Zhang, Z, Zhao, F, Zhao, J, Zhao, R, Zhao, S, Zhao, T, Zheng, D, Zheng, H, Zheng, M, Zheng, Y, Zhong, W, Zhou, J, Zhou, L, Zhou, N, Zhou, S, Zhou, X, Zhu, J, Zhu, K, Zhuang, H, Zong, L, Zou, J, Abusleme A., Adam T., Ahmad S., Aiello S., Akram M., Ali N., An F. P., An G. P., An Q., Andronico G., Anfimov N., Antonelli V., Antoshkina T., Asavapibhop B., de Andre J. P. A. M., Babic A., Balantekin A. B., Baldini W., Baldoncini M., Band H. R., Barresi A., Baussan E., Bellato M., Bernieri E., Biare D., Birkenfeld T., Bishai M., Blin S., Blum D., Blyth S., Bordereau C., Brigatti A., Brugnera R., Budano A., Burgbacher P., Buscemi M., Bussino S., Busto J., Butorov I., Cabrera A., Cai H., Cai X., Cai Y. K., Cai Z. Y., Cammi A., Campeny A., Cao C. Y., Cao G. F., Cao J., Caruso R., Cerna C., Chang J. F., Chang Y., Chen H. S., Chen P. A., Chen P. P., Chen S. M., Chen S. J., Chen X. R., Chen Y. W., Chen Y. X., Chen Y., Chen Z., Cheng J., Cheng Y. P., Cheng Z. K., Chepurnov A., Cherwinka J. J., Chiarello F., Chiesa D., Chimenti P., Chu M. C., Chukanov A., Chuvashova A., Clementi C., Clerbaux B., Di Lorenzo S. C., Corti D., Costa S., Dal Corso F., Cummings J. P., Dalager O., De La Taille C., Deng F. S., Deng J. W., Deng Z., Deng Z. Y., Depnering W., Diaz M., Ding X. F., Ding Y. Y., Dirgantara B., Dmitrievsky S., Diwan M. V., Dohnal T., Donchenko G., Dong J. M., Dornic D., Doroshkevich E., Dove J., Dracos M., Druillole F., Du S. X., Dusini S., Dvorak M., Dwyer D. A., Enqvist T., Enzmann H., Fabbri A., Fajt L., Fan D. H., Fan L., Fang C., Fang J., Fatkina A., Fedoseev D., Fekete V., Feng L. C., Feng Q. C., Fiorentini G., Ford R., Formozov A., Fournier A., Franke S., Gallo J. P., Gan H. N., Gao F., Garfagnini A., Gottel A., Genster C., Giammarchi M., Giaz A., Giudice N., Giuliani F., Gonchar M., Gong G. H., Gong H., Gorchakov O., Gornushkin Y., Grassi M., Grewing C., Gromov M., Gromov V., Gu M. H., Gu W. Q., Gu X. F., Gu Y., Guan M. Y., Guardone N., Gul M., Guo C., Guo J. Y., Guo L., Guo W. L., Guo X. H., Guo Y. H., Guo Z., Haacke M., Hackenburg R. W., Hackspacher P., Hagner C., Han R., Han Y., Hans S., He M., He W., Heeger K. M., Heinz T., Heng Y. K., Herrera R., Higuera A., Hong D. J., Hor Y. K., Hou S. J., Hsiung Y. B., Hu B. Z., Hu H., Hu J. R., Hu J., Hu S. Y., Hu T., Hu Z. J., Huang C. H., Huang G. H., Huang H. X., Huang Q. H., Huang W. H., Huang X. T., Huang Y. B., Huber P., Hui J. Q., Huo L., Huo W. J., Huss C., Hussain S., Insolia A., Ioannisian A., Ioannisyan D., Isocrate R., Jaffe D. E., Jen K. L., Ji X. L., Ji X. P., Ji X. Z., Jia H. H., Jia J. J., Jian S. Y., Jiang D., Jiang X. S., Jin R. Y., Jing X. P., Johnson R. A., Jollet C., Jones D., Joutsenvaara J., Jungthawan S., Kalousis L., Kampmann P., Kang L., Karagounis M., Kazarian N., Kettell S. H., Khan A., Khan W., Khosonthongkee K., Kinz P., Kohn S., Korablev D., Kouzakov K., Kramer M., Krasnoperov A., Krokhaleva S., Krumshteyn Z., Kruth A., Kutovskiy N., Kuusiniemi P., Lachacinski B., Lachenmaier T., Landini C., Langford T. J., Lee J., Lee J. H. C., Lefevre F., Lei L., Lei R., Leitner R., Leung J., Li D. M., Li F., Li H. T., Li H. L., Li J., Li J. J., Li J. Q., Li K. J., Li M. Z., Li N., Li Q. J., Li R. H., Li S. C., Li S. F., Li S. J., Li T., Li W. D., Li W. G., Li X. M., Li X. N., Li X. L., Li X. Q., Li Y., Li Y. F., Li Z. B., Li Z. Y., Liang H., Liang J. J., Liebau D., Limphirat A., Limpijumnong S., Lin C. J., Lin G. L., Lin S. X., Lin T., Lin Y. H., Ling J. J., Link J. M., Lippi I., Littenberg L., Littlejohn B. R., Liu F., Liu H., Liu H. B., Liu H. D., Liu H. J., Liu H. T., Liu J. C., Liu J. L., Liu M., Liu Q., Liu R. X., Liu S. Y., Liu S. B., Liu S. L., Liu X. W., Liu Y., Lokhov A., Lombardi P., Loo K., Lorenz S., Lu C., Lu H. Q., Lu J. B., Lu J. G., Lu S. X., Lu X. X., Lubsandorzhiev B., Lubsandorzhiev S., Ludhova L., Luk K. B., Luo F. J., Luo G., Luo P. W., Luo S., Luo W. M., Lyashuk V., Ma Q. M., Ma S., Ma X. B., Ma X. Y., Ma Y. Q., Malyshkin Y., Mantovani F., Mao Y. J., Mari S. M., Marini F., Marium S., Marshall C., Martellini C., Martin-Chassard G., Caicedo D. A. M., Martini A., Martino J., Mayilyan D., McDonald K. T., McKeown R. D., Muller A., Meng G., Mednieks I., Meng Y., Meregaglia A., Meroni E., Meyhofer D., Mezzetto M., Miller J., Miramonti L., Monforte S., Montini P., Montuschi M., Morozov N., Muralidharan P., Napolitano J., Nastasi M., Naumov D. V., Naumova E., Nemchenok I., Nikolaev A., Ning F. P., Ning Z., Nunokawa H., Oberauer L., Ochoa-Ricoux J. P., Olshevskiy A., Ortica F., Pan H. R., Paoloni A., Park J., Parkalian N., Parmeggiano S., Patton S., Payupol T., Pec V., Pedretti D., Pei Y. T., Pelliccia N., Peng A. G., Peng H. P., Peng J. C., Perrot F., Petitjean P. A., Rico L. F. P., Popov A., Poussot P., Pratumwan W., Previtali E., Pun C. S. J., Qi F. Z., Qi M., Qian S., Qian X., Qian X. H., Qiao H., Qin Z. H., Qiu S. K., Rajput M., Ranucci G., Raper N., Re A., Rebber H., Rebii A., Ren B., Ren J., Reveco C. M., Rezinko T., Ricci B., Robens M., Roche M., Rodphai N., Rohwer L., Romani A., Rosero R., Roskovec B., Roth C., Ruan X. C., Ruan X. D., Rujirawat S., Rybnikov A., Sadovsky A., Saggese P., Salamanna G., Sangka A., Sanguansak N., Sawangwit U., Sawatzki J., Sawy F., Schever M., Schuler J., Schwab C., Schweizer K., Selivanov D., Selyunin A., Serafini A., Settanta G., Settimo M., Shahzad M., Shi G., Shi J. Y., Shi Y. J., Shutov V., Sidorenkov A., Simkovic F., Sirignano C., Siripak J., Sisti M., Slupecki M., Smirnov M., Smirnov O., Sogo-Bezerra T., Songwadhana J., Soonthornthum B., Sotnikov A., Sramek O., Sreethawong W., Stahl A., Stanco L., Stankevich K., Stefanik D., Steiger H., Steiner H., Steinmann J., Stender M., Strati V., Studenikin A., Sun G. X., Sun L. T., Sun J. L., Sun S. F., Sun X. L., Sun Y. J., Sun Y. Z., Suwonjandee N., Szelezniak M., Tang J., Tang Q., Tang X., Tietzsch A., Tkachev I., Tmej T., Treskov K., Troni G., Trzaska W., Tse W. -H., Tull C. E., Tuve C., van Waasen S., Boom J. V. D., Vassilopoulos N., Vedin V., Verde G., Vialkov M., Viaud B., Viren B., Volpe C., Vorobel V., Votano L., Walker P., Wang C., Wang C. H., Wang E., Wang G. L., Wang J., Wang K. Y., Wang L., Wang M. F., Wang M., Wang N. Y., Wang R. G., Wang S. G., Wang W., Wang W. S., Wang X., Wang X. Y., Wang Y., Wang Y. F., Wang Y. G., Wang Y. M., Wang Y. Q., Wang Z., Wang Z. M., Wang Z. Y., Watcharangkool A., Wei H. Y., Wei L. H., Wei W., Wei Y. D., Wen L. J., Whisnant K., White C. G., Wiebusch C., Wong S. C. F., Wong H. L. H., Wonsak B., Worcester E., Wu C. H., Wu D. R., Wu F. L., Wu Q., Wu W. J., Wu Z., Wurm M., Wurtz J., Wysotzki C., Xi Y. F., Xia D. M., Xie Y. G., Xie Z. Q., Xing Z. Z., Xu D. L., Xu F. R., Xu H. K., Xu J. L., Xu J., Xu M. H., Xu T., Xu Y., Xue T., Yan B. J., Yan X. B., Yan Y. P., Yang A. B., Yang C. G., Yang H., Yang J., Yang L., Yang X. Y., Yang Y. F., Yang Y. Z., Yao H. F., Yasin Z., Ye J. X., Ye M., Yegin U., Yeh M., Yermia F., Yi P. H., You Z. Y., Young B. L., Yu B. X., Yu C. X., Yu C. Y., Yu H. Z., Yu M., Yu X. H., Yu Z. Y., Yuan C. Z., Yuan Y., Yuan Z. X., Yuan Z. Y., Yue B. B., Zafar N., Zambanini A., Zeng P., Zeng S., Zeng T. X., Zeng Y. D., Zhan L., Zhang C., Zhang F. Y., Zhang G. Q., Zhang H. H., Zhang H. Q., Zhang J., Zhang J. B., Zhang J. W., Zhang P., Zhang Q. M., Zhang T., Zhang X. M., Zhang X. T., Zhang Y., Zhang Y. H., Zhang Y. M., Zhang Y. P., Zhang Y. X., Zhang Y. Y., Zhang Z. J., Zhang Z. P., Zhang Z. Y., Zhao F. Y., Zhao J., Zhao R., Zhao S. J., Zhao T. C., Zheng D. Q., Zheng H., Zheng M. S., Zheng Y. H., Zhong W. R., Zhou J., Zhou L., Zhou N., Zhou S., Zhou X., Zhu J., Zhu K. J., Zhuang H. L., Zong L., Zou J. H., Abusleme, A, Adam, T, Ahmad, S, Aiello, S, Akram, M, Ali, N, An, F, An, G, An, Q, Andronico, G, Anfimov, N, Antonelli, V, Antoshkina, T, Asavapibhop, B, de Andre, J, Babic, A, Balantekin, A, Baldini, W, Baldoncini, M, Band, H, Barresi, A, Baussan, E, Bellato, M, Bernieri, E, Biare, D, Birkenfeld, T, Bishai, M, Blin, S, Blum, D, Blyth, S, Bordereau, C, Brigatti, A, Brugnera, R, Budano, A, Burgbacher, P, Buscemi, M, Bussino, S, Busto, J, Butorov, I, Cabrera, A, Cai, H, Cai, X, Cai, Y, Cai, Z, Cammi, A, Campeny, A, Cao, C, Cao, G, Cao, J, Caruso, R, Cerna, C, Chang, J, Chang, Y, Chen, H, Chen, P, Chen, S, Chen, X, Chen, Y, Chen, Z, Cheng, J, Cheng, Y, Cheng, Z, Chepurnov, A, Cherwinka, J, Chiarello, F, Chiesa, D, Chimenti, P, Chu, M, Chukanov, A, Chuvashova, A, Clementi, C, Clerbaux, B, Di Lorenzo, S, Corti, D, Costa, S, Dal Corso, F, Cummings, J, Dalager, O, De La Taille, C, Deng, F, Deng, J, Deng, Z, Depnering, W, Diaz, M, Ding, X, Ding, Y, Dirgantara, B, Dmitrievsky, S, Diwan, M, 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Abstract

To maximize the light yield of the liquid scintillator (LS) for the Jiangmen Underground Neutrino Observatory (JUNO), a 20 t LS sample was produced in a pilot plant at Daya Bay. The optical properties of the new LS in various compositions were studied by replacing the gadolinium-loaded LS in one antineutrino detector. The concentrations of the fluor, PPO, and the wavelength shifter, bis-MSB, were increased in 12 steps from 0.5 g/L and <0.01 mg/L to 4 g/L and 13 mg/L, respectively. The numbers of total detected photoelectrons suggest that, with the optically purified solvent, the bis-MSB concentration does not need to be more than 4 mg/L. To bridge the one order of magnitude in the detector size difference between Daya Bay and JUNO, the Daya Bay data were used to tune the parameters of a newly developed optical model. Then, the model and tuned parameters were used in the JUNO simulation. This enabled to determine the optimal composition for the JUNO LS: purified solvent LAB with 2.5 g/L PPO, and 1 to 4 mg/L bis-MSB.

Published
2021

16. Accurate occlusion-driven maxillary reconstruction with deep circumflex iliac artery flap using computer-assisted techniques and intraoral anastomosis: a case series.

Author

Qiu, S.-Y., Shan, X.-F., Kang, Y.-F., Ding, M.-K., Zhang, L., and Cai, Z.-G.

Subjects
ILIAC artery, SURGICAL anastomosis, MAXILLOFACIAL surgery, ORAL surgery, SURGICAL complications, FREE flaps
Abstract

The aim of this study was to evaluate the feasibility and accuracy of occlusion-driven maxillary reconstruction with the deep circumflex iliac artery (DCIA) flap, using computer-assisted design and manufacturing (CAD/CAM) technology and intraoral anastomosis. The data of 11 patients who underwent occlusion-driven maxillary reconstruction with this method between December 2018 and December 2020 in the Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology were reviewed retrospectively. Postoperative complications and functional and aesthetic outcomes were recorded. The accuracy of the postoperative restoration was assessed using Geomagic Control 2014. Reconstruction was successful in nine patients; all were satisfied with their aesthetic and functional outcomes. One patient underwent extraoral anastomosis after failure of intraoral anastomosis. In another patient, the DCIA flap had to be removed after the operation because of flap failure. Among the 10 patients with DCIA flap success, colour map analysis showed a mean deviation of 0.40 ± 0.08 mm between the preoperative and postoperative craniomaxillary models. Thus, occlusion-driven maxillary reconstruction with the DCIA flap, using CAD/CAM technology and intraoral anastomosis, appears to be a feasible and accurate method for the repair of maxillary defects. [ABSTRACT FROM AUTHOR]

Published
2023
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18. Bone resorption after maxillary reconstruction with the vascularized free iliac flap.

Author

Chen, H.-M., Kang, Y.-F., Lv, X.-M., Shan, X.-F., and Cai, Z.-G.

Subjects
BONE resorption, FREE flaps, CANCELLOUS bone, COMPACT bone, BONE grafting, ILIUM, BONE density
Abstract

The aim of this study was to evaluate the resorption of the iliac bone after maxillary reconstruction with a vascularized free iliac flap. Twenty-seven patients with maxillary defects who underwent maxillary reconstruction with the vascularized free iliac flap between January 2017 and January 2021 were included. Computed tomography (CT) images taken at 1 week, approximately 6 months, and 1 year after the surgery were used for evaluation. The total iliac bone thickness and height, cortical bone thickness, and cancellous bone density were measured in the CT images. Compared with 1 week after the surgery, the total thickness and height of the iliac bone were reduced significantly 1 year after the surgery, and the cortical bone thickness and cancellous bone density were reduced significantly at 6 months and 1 year after the surgery. Compared with 6 months after the surgery, cancellous bone density was reduced significantly 1 year after the surgery. In conclusion, during the first year after maxillary reconstruction with a vascularized free iliac flap, there was significant resorption of iliac bone, including the total iliac bone thickness and height, the cortical bone thickness, and the cancellous bone density. [ABSTRACT FROM AUTHOR]

Published
2023
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20. Global prevalence, risk factors, and reporting practice of needlestick and sharps injuries among dental students: a systematic review and meta-analysis.

Author

Huang, J., Li, N., Xu, H., Liu, Y., An, N., and Cai, Z.

Abstract

Background: Dental students are vulnerable to needlestick injuries (NSIs) due to their inadequate training. However, the global prevalence of NSI among dental students is unknown.Aim: To determine the pooled prevalence among dental students, epidemiological profile, and risk factors for NSI.Methods: A systematic review was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The review protocol was registered at the International Prospective Register of Systematic Reviews (CRD 42022312778). Eligible studies were identified from PubMed, Scopus, Web of Science, Embase, OVID, and EBSCO databases. A meta-analysis with a random effects model was performed to estimate the pooled prevalence, and meta-regression was conducted to explore heterogeneity among studies.Findings: A total of 25 studies from 15 countries met the inclusion criteria. The estimated pooled prevalence of NSI among dental students was 44% (95% confidence interval: 38-51%). Local anaesthesia, tooth cleaning or scaling, and waste disposal were associated with highest risk for NSI. Most studies observed under-reporting of NSI. Dental students had inadequate knowledge regarding post-exposure management.Conclusion: Dental students had a high prevalence and low reporting rate of NSI exposure. Inadequate knowledge might increase the probability of NSI exposure. [ABSTRACT FROM AUTHOR]

Published
2022
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22. Preoperative oral carbohydrates in elderly patients undergoing free flap surgery for oral cancer: randomized controlled trial.

Author

Wu, H.-Y., Yang, X.-D., Yang, G.-Y., Cai, Z.-G., Shan, X.-F., and Yang, Y.

Subjects
FREE flaps, OLDER patients, ORAL cancer, ORAL surgery, RANDOMIZED controlled trials, ONCOLOGIC surgery
Abstract

The aim of this study was to evaluate the safety of carbohydrate intake 2 hours before surgery in elderly patients undergoing free flap surgery for oral cancer. Elderly patients undergoing free flap surgery between September 2019 and January 2021 were randomly divided into control (n = 43) and intervention (n = 43) groups. Control group patients fasted for 6 hours and were forbidden from drinking water for 4 hours before surgery. Intervention group patients fasted for 6 hours and were forbidden from drinking after the oral administration of 5 ml/kg carbohydrate (≤400 ml) 2 hours before surgery. The main outcome measures were aspiration, fasting blood glucose level, insulin concentration, insulin resistance index (fasting at admission, prior to anaesthesia induction, immediately after surgery, and at 6 a.m. on postoperative days 1 and 2), and comfort before and after surgery. No aspiration occurred in any of the patients during anaesthesia. There were significant differences in fasting blood glucose, insulin concentration, and insulin resistance index between the control and intervention groups prior to anaesthesia induction, immediately after surgery, and on day 1 after surgery (P < 0.01). Thirst (P = 0.001) and hunger (P = 0.003) differed significantly between the two groups prior to anaesthesia induction. The intake of oral carbohydrate 2 hours before surgery was both safe and effective for elderly patients with oral cancer undergoing free flap surgery and could relieve the physiological stress response. [ABSTRACT FROM AUTHOR]

Published
2022
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24. Mitochondrial quality control in cartilage damage and osteoarthritis: new insights and potential therapeutic targets.

Author

Liu, D., Cai, Z.-J., Yang, Y.-T., Lu, W.-H., Pan, L.-Y., Xiao, W.-F., and Li, Y.-S.

Abstract

Osteoarthritis (OA) is a multifactorial arthritic disease of weight-bearing joints concomitant with chronic and intolerable pain, loss of locomotion and impaired quality of life in the elderly population. Although the prevalence of OA increases with age, its specific mechanisms have not been elucidated and effective therapeutic disease-modifying drugs have not been developed. As essential organelles in chondrocytes, mitochondria supply energy and play vital roles in cellular metabolism, proliferation and apoptosis. Mitochondrial quality control (MQC) is the key mechanism to coordinate various mitochondrial biofunctions, primarily through mitochondrial biogenesis, dynamics, autophagy and the newly discovered mitocytosis. An increasing number of studies have revealed that a loss of MQC homeostasis contributes to the cartilage damage during the occurrence and development of OA. Several master MQC-associated signaling pathways and regulators exert chondroprotective roles in OA, while cartilage damage-related molecular mechanisms have been partially identified. In this review, we summarized known mechanisms mediated by dysregulated MQC in the pathogenesis of OA and latent bioactive ingredients and drugs for the prevention and treatment of OA through the maintenance of MQC. [ABSTRACT FROM AUTHOR]

Published
2022
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26. Detection of facial landmarks by a convolutional neural network in patients with oral and maxillofacial disease.

Author

Ding, M., Kang, Y., Yuan, Z., Shan, X., and Cai, Z.

Subjects
FACIAL paralysis, CONVOLUTIONAL neural networks, BELL'S palsy, ARTIFICIAL intelligence, ORAL diseases, PHYSICIANS
Abstract

Facial nerve dysfunction is common in patients with Bell's palsy, trauma, tumour, or iatrogenic injuries. Imaging assessment is the most convenient method for patients and their treating physician. With developments in artificial intelligence (AI), manual work will be replaced. In this study, a database of facial images of patients with oral and maxillofacial diseases was set up to develop a facial nerve functional assessment system based on AI. This database was then used to evaluate the accuracy of a state-of-the-art algorithm for facial landmark detection named 'HRNet'. Utilizing this database and with appropriate human intervention, HRNet was used in facial annotation. The accuracy of annotations was evaluated through the normalized mean error. A total of 912 images were collected from 300 people; 546 of these images had abnormal features including defects, swelling, scars, or facial paralysis. The accuracy for the abnormal group was lower than that for the normal group before and after training, but improvements in accuracy were identified in both groups post-training. In conclusion, this new database demonstrates the ability of HRNet to localize facial landmarks in patients with oral and maxillofacial diseases. More images for training should be added to this database to diversify it in the future. [ABSTRACT FROM AUTHOR]

Published
2021
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35. Shear-band structure and chemistry in a Zr-based metallic glass probed with nano-beam x-ray fluorescence and transmission electron microscopy.

Author

Liu, C., Cai, Z., Xia, X., Roddatis, V., Yuan, R., Zuo, J.M., and Maaß, R.

Subjects
*METALLIC glasses, *X-ray fluorescence, *TRANSMISSION electron microscopy, *CHEMISTRY, *ELECTRON spectroscopy, *FLUORESCENCE spectroscopy
Abstract

An apparent local change in chemistry in shear-bands can be observed in a Zr-based metallic glass using correlative x-ray fluorescence and electron spectroscopy. Further analysis suggests that this finding is due to the local volumetric change of the shear-band structure. These results emphasize the importance of correlated analytical methods to unambiguously reveal structural and chemical changes caused by strain localization in metallic glasses. Unlabelled Image [ABSTRACT FROM AUTHOR]

Published
2019
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36. Cortical bone resorption of fibular bone after maxillary reconstruction with a vascularized fibula free flap: a computed tomography imaging study.

Author

Kang, Y.-F., Liang, J., He, Z., Xie, S., Zhang, L., Shan, X.-F., and Cai, Z.-G.

Subjects
FIBULA, COMPACT bone, BONE resorption, FREE flaps, DIAGNOSTIC imaging, COMPUTED tomography
Abstract

This study was performed to evaluate the cortical bone resorption of fibular bone after maxillary reconstruction with a fibula free flap. A total of 35 patients with maxillary defects that were repaired using a fibula flap (62 fibula segments) between January 2011 and January 2016 were enrolled. Computed tomography (CT) images taken 1 week and 1 year postoperative were used to evaluate cortical bone resorption. The 62 fibula segments were measured on four different surfaces in the CT images. At 1 week, the thickness of the cortical bone was 2.57 ± 0.58 mm, 2.72 ± 0.46 mm, 3.84 ± 0.98 mm, and 4.36 ± 0.90 mm for the exterior, interior, superior, and inferior sides, respectively. At approximately 1 year, the cortical bone thickness was significantly reduced to 2.00 ± 0.65 mm (P < 0.01), 2.25 ± 0.60 mm (P < 0.01), 3.37 ± 0.90 mm (P < 0.01), and 2.96 ± 0.84 mm (P < 0.01) for the exterior, interior, superior, and inferior sides, respectively. The cortical bone thickness of fibular bone is significantly reduced 1 year after the restoration of maxillary defects with a fibula free flap, most significantly on the inferior side. [ABSTRACT FROM AUTHOR]

Published
2019
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37. Botulinum toxin A treatment of epiphora secondary to autologous submandibular gland transplantation.

Author

Shan, X.F., Cai, Z.-G., Yu, G.-Y., and Lv, L.

Subjects
DROOLING, BOTULINUM toxin, BOTULINUM A toxins, SUBMANDIBULAR gland
Abstract

Abstract The aim of this study was to explore whether botulinum toxin A (BTXA) injection treats epiphora secondary to submandibular gland (SMG) transplantation for severe keratoconjunctivitis sicca. Fifteen patients with epiphora after SMG transplantation were separated to three groups, and received 15 U, 20 U and 25 U BTXA injection in the transplanted SMG, respectively. Secretion of transplanted SMG was assessed subjectively by visual analogue scale (VAS) regarding epiphora, and objectively by Schirmer test. There were no significant differences in the 15-U BTXA group regarding the values of the VAS on epihora before and 1 month after BTXA injection. While in 20-U group and 25-U group, the values of VAS on epihora decreased significantly after BTXA injection, and lasted for 6 months. Under resting conditions, the secretion of transplanted SMG decreased 64.4%, 73.0% and 78.0% in 15-U, 20-U and 25-U groups, respectively (P < 0.01), in 1 month after BTXA injection; significant secretion decreasing lasted 3 months only in the 25-U BTXA group. BTXA injection can decrease the secretion of transplanted SMG significantly, relieving the symptoms of epiphora; 25 U BTXA is a suitable dose to treat 'opportunistic epiphora' after SMG transplantation. [ABSTRACT FROM AUTHOR]

Published
2019
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42. Factors influencing the long-term results of autologous microvascular submandibular gland transplantation for severe dry eye disease.

Author

Zhang, L., Su, J.-Z., Cai, Z.-G., Lv, L., Zou, L.-H., Liu, X.-J., Wu, J., Zhu, Z.-H., Mao, C., Wang, Y., Peng, X., Song, B., Li, X.-X., and Yu, G.-Y.

Subjects
SUBMANDIBULAR gland, EYE diseases, MEIBOMIAN glands, TRANSPLANTATION of organs, tissues, etc., BOTULINUM toxin, VISUAL acuity
Abstract

Abstract We assessed long-term outcomes of autologous microvascular submandibular gland (SMG) transplantation for severe dry eye disease and investigated factors influencing long-term results. From August 1999 to January 2015, 185 patients (200 eyes) with severe dry eye received SMG transplantation. Subjective assessments and ophthalmologic evaluations were performed before and after transplantation. Follow-up results showed successful transplantation in 180 of 200 eyes (success rate: 90%), resulting in marked symptomatic relief of xerophthalmia. Surgery failed due to vascular thrombosis (15 glands) and duct obstruction (5 glands). Follow-up data were available for 163 eyes. Epiphora occurred in 98 (60.1%) eyes and was effectively managed by surgical reduction of graft, topical atropine gel and botulinum toxin injection. Wharton's duct obstruction occurred in 16 (10.6%) eyes and was treated by duct reconstruction. Subjective satisfaction was achieved in 143 (87.7%) eyes. Mean score of fluorescent staining reduced from 11.25 ± 1.42 to 7.25 ± 3.37. Postoperative best-corrected visual acuity improved in 85 (56.3%) eyes. Our clinical experience proved that SMG transplantation is effective and grants long-term improvement in severe dry eye. Secretory function of transplanted SMGs remains active and stable. Blood vessel thrombosis, Wharton's duct obstruction, and epiphora are primary factors influencing results. [ABSTRACT FROM AUTHOR]

Published
2019
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44. Differential diagnosis of IgG4-related sialadenitis, primary Sjögren syndrome, and chronic obstructive submandibular sialadenitis.

Author

Hong, X., Li, W., Xie, X.-Y., Zhang, Z.-Y., Chen, Y., Gao, Y., Peng, X., Su, J.-Z., Zhang, Y.-Y., Wang, Z., Cai, Z.-G., Zhang, L., Liu, Y.-Y., He, J., Ren, L.-M., Li, Z.-G., and Yu, G.-Y.

Subjects
SALIVARY gland diseases, SIALADENITIS, SJOGREN'S syndrome, OBSTRUCTIVE lung diseases, DIAGNOSIS, THERAPEUTICS
Abstract

Our aim was to differentiate IgG4-related sialadenitis, primary Sjögren syndrome, and chronic obstructive submandibular sialadenitis by analysing clinical, radiographic, and pathological features. Fifty-five patients, 50, and 50 were enrolled, respectively and their baseline characteristics and serological, sialographic, and pathological findings compared. The male:female ratio for IgG4-related sialadenitis was 1:1.2 for primary Sjögren syndrome 1:15.7, and for chronic obstructive submandibular sialadenitis1:0.92. Numbers with enlarged salivary glands were 55, 16, and 50; with xerostomia 26, 48, and 0; with a history of allergy 26, 4, and 6, and with coexisting systemic disease 12, 19, and 0 (p = 0.14). Mean (SD) serum IgG4 concentrations were 109.1 (97.9), 4.9. (1.9) g/L, and 5.3 (1.6) g/L, p < 0.001 in all cases. Sialography showed enlargement of the gland, dilatation of the duct, and slightly decreased secretory function in IgG4-related disease; obvious sialectasia and decreased secretory function in Sjögren syndrome; and dilatation of Wharton’s duct and filling defects in obstructive sialadenitis. Histopathological examination showed lymphoplasmacytic infiltration with storiform fibrosis, lymphoplasmacytic inflammation and lymphoepithelial lesions, and dilatation of the duct with epithelial metaplasia in the three groups, respectively. The number of IgG4-positive plasma cells was 123 (45)/HPF, 8 (3)/HPF, and 5 (4)/HPF, while the IgG4-/IgG-positive cell ratio was 71.7 (13.9)%, 4.6 (2.5)%, 18.9 (19.7)%, respectively (p < 0.001). The three conditions have different clinical, radiographic, and pathological features that provide important clues to the differential diagnosis. Serological and histological tests are important, and comprehensive consideration is necessary. [ABSTRACT FROM AUTHOR]

Published
2017
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47. Partial sialoadenectomy for the treatment of benign tumours in the submandibular gland.

Author

Ge, N., Peng, X., Zhang, L., Cai, Z.-G., Guo, C.-B., and Yu, G.-Y.

Subjects
BENIGN tumors, TUMORS, SUBMANDIBULAR gland, SALIVARY gland diseases, PAROTID glands
Abstract

The conventional treatment for benign tumours arising in the submandibular gland (SMG) has always involved whole gland excision with the tumour. In light of developments in parotid gland functional surgery, this prospective study was performed to evaluate the effectiveness and safety of partial sialoadenectomy (PS) for benign tumours in comparison with conventional total sialoadenectomy (TS). Thirty-one consecutive patients with a preoperative diagnosis of benign tumour in the SMG were included in the study from December 2008 to December 2010. Eleven patients were treated with PS and 20 patients underwent conventional TS. Salivary gland function and surgery-related complications were assessed. No difference in resting saliva flow was found between the two groups before the operation, while this was significantly higher in the PS group than in the TS group at 1 year after surgery ( P = 0.009). With regard to complications, there was less deformity in facial appearance in the PS group. There was no recurrence in any of the 31 patients during the follow-up period (range 41–82 months). It is believed that this modification to SMG surgery is consistent with the idea of functional and minimal invasive salivary gland surgery. This technique represents a good choice for the management of benign tumours of the SMG for appropriately selected cases. [ABSTRACT FROM AUTHOR]

Published
2016
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48. Surgical navigation-assisted mandibular reconstruction with fibula flaps.

Author

Shan, X.-F., Chen, H.-M., Liang, J., Huang, J.-W., Zhang, L., Cai, Z.-G., and Guo, Chuanbin

Subjects
MANDIBULAR prosthesis, FIBULA, SURGICAL flaps, COMPUTED tomography, PREOPERATIVE period, COMPUTER-assisted surgery, SURGERY
Abstract

The mandible has an important role in appearance and function. The aim of this study was to describe and evaluate surgical navigation-assisted mandibular reconstruction with the fibula flap. Patients recruited into the study had a custom dental splint fabricated to maintain the mandible in a fixed position. Later, the computed tomography (CT) scan, preoperative design, and operation on the mandible were done in the same position. At 1 week after surgery, a CT scan was done to evaluate the repeatability between the preoperative design and the postoperative result. Twenty patients were enrolled in this study. Good repeatability between the postoperative CT and the preoperative design was found. The repeatability between the preoperative plan and postoperative outcome was 79.1 ± 8.6% at within 1 mm, 87.1 ± 6.7% at within 2 mm, and 91.9 ± 5.4% at within 3 mm. From this study, it can be concluded that surgical navigation techniques can precisely transfer the preoperative design to the operation in mandible reconstruction with a fibula flap. This will assist the surgeon in achieving good cosmetic and functional outcomes. [ABSTRACT FROM AUTHOR]

Published
2016
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49. Large-scale Integration of Renewable Energies and Impact on Storage Demand in a European Renewable Power System of 2050.

Author

Bussar, C., Stöcker, P., Cai, Z., Jr.Moraes, L., Alvarez, R., Chen, H., Breuer, C., Moser, A., Leuthold, M., and Sauer, D.U.

Abstract

Driven 1 by decreasing prices for photovoltaic (PV) systems and incentive programs of different governments almost 100 GW of PV and over 100 GW of wind turbines (WT) have been integrated in the European power system today (2014). In some areas, the electricity generation already exceeds the demand, pushing the existing transport infrastructure to its limits in certain hours. In order to reach the European Commission's targets for 2050, the system integration will at some point require flexibility sources independent of conventional generation in order to keep today's standard in security of supply. There are several sources of flexibility. Together these flexibility sources will ensure the match of demand and supply at any given time. Energy storage systems can provide this flexibility by shifting of load in time while transmission grids provide the shift of load in space. Up to a certain extent, transmission capacity and storage capacity can replace each other, i.e. storage can reduce the load on transmission infrastructure by mitigating local peaks in load and/or generation. For the transition to a fully renewable energy system in 2050, major changes have to be achieved in the structure of the power supply system. The simulation tool GENESYS is a holistic approach to optimize the allocation and size of different generation technologies, storage systems and transnational grids of a European power system. The source code for the simulation tool is available free of charge under a public license. It can be freely parameterized by the user which allows the study of different electricity systems under the users’ assumptions with regard to load, generation potential and cost structure of the different system components. This publication will give an introduction to the simulation framework, the system model and the optimization strategy. Optimization results obtained with GENESYS for a fully renewable electricity system and a cost structure expected for 2050 will be presented together with sensitivity analyses investigating the main assumptions. The focus is the optimal allocation of PV and WT in a European electricity system, the resulting demand for storage capacities of different technologies and the capacity of the overlay grid. [ABSTRACT FROM AUTHOR]

Published
2015
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