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Purpose: The aim of the study was to evaluate the survival rate of resin-bonded fixed partial dentures delivered between 1993 and 2003 in the Department of Prosthodontics of the University of Turin and in several private practices. Materials and Methods: The analysis took into consideration the following variables: preparations, metallic alloys, metal preparation and conditioning of the inner surfaces, isolation during cementation, type of cement, kind of prostheses, number of abutments, and number of missing teeth included in the prostheses. Results: The estimated survival probability for the first debonding or failure was 85% after 5 years and 71% after 10 years. Conclusions: The use of dental dam during cementation reduced the risk of debonding. No differences in survival rate were found for the other parameters.—Reprinted with permission of Quintessence Publishing. [Copyright &y& Elsevier]

Products of different origin, time of collection, and activities fall under the general term of colostrum and, therefore, great variability in composition as well as in the concentration of its components has been reported in the literature. In the present study, we describe the standardization of a bovine colostrum derivative and the characterization of its bioactive components. Evaluation of the most representative agents (lactoferrin, transferrin, IL-2, IFN-γ, tumor necrosis factor, IgG, and IgA) showed that a marked decrease in active components occurs after the first few hours. Bovine colostrum was, therefore, collected up to the fifth hour after delivery from Holstein cows, in the presence of preservatives, and immediately frozen. A protocol of centrifugation, filtration, and lyophilization was then applied to pools of colostrum from at least 30 cows to obtain a stable, sterile, standardized product. Preservatives were removed by dialysis. Evaluation of the active biological components of colostrum showed that the final product of colostrums contained significant and reproducible amounts of bioactive factors, including cytokines, immunomodulating factors, growth factors, and immunoglobulins. The final product appeared, therefore, as a sterile, pyrogen-free, standardized derivative of bovine colostrum with a high concentration of bioactive components. [ABSTRACT FROM AUTHOR]