Search

Your search keyword '"Diaz Fernandez, P."' showing total 11 results
Start Over Author "Diaz Fernandez, P." Publisher elsevier b.v.
11 results on '"Diaz Fernandez, P."'

3. Results of Transfibular Total Ankle Arthroplasty. A Series of 50 Implants.

Author

Abarquero-Diezhandino, Ana, Vacas Sánchez, Elena, Diaz Fernandez, Rodrigo, and Vilá y Rico, Jesús

Abstract

Total ankle arthroplasty has become popular in the last few years. The lateral transfibular approach is an alternative to the traditional anterior approach. The purpose of this study was to evaluate our 50 first and consecutive clinical and radiological outcomes of transfibular total ankle replacements (Trabecular Metal Total AnkleR Zimmer Biomet, Warsaw, IN) with a follow-up of at least 3 years. This retrospective study included 50 patients. The main indication was post-traumatic osteoarthritis (n = 41). The mean age was 59 (range = 39-81). All patients were followed for at least 36 months postoperatively. Patients were assessed with the American Orthopaedic Foot & Ankle Society (AOFAS) Ankle Hindfoot Score and Visual analog scale (VAS) preoperatively and postoperatively. Range of motion and radiological measures were assessed as well. Postoperatively, patients demonstrated statistically significant improvement in the AOFAS score from 32 (range = 14-46) to 80 (range = 60-100) (p <.01) and VAS from 7.8 (range = 6.1-9.7) to 1.3 (range = 0-6) (p <.01). The average total range of motion increased significantly from 19.8° to 29.2° of plantarflexion and 6.8° to 13.5° of dorsiflexion. Alignment measured by alpha, beta, and gamma angles was satisfactorily achieved. No patient demonstrated any radiographic evidence of tibial or talar lucency at the final follow-up. Five patients (10%) experienced delayed wound healing. One patient (2%) developed a postoperative prosthetic infection. One patient (2%) developed fibular pseudoarthrosis and 2 patients (4%) suffered impingement. Two patients (4%) needed surgery for symptomatic fibular hardware. This study found excellent clinical and radiological results of transfibular total ankle replacement. This is a safe and effective option that allows the correction of sagittal and coronal malalignment. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

4. Unveiling the two-proton halo character of 17Ne: Exclusive measurement of quasi-free proton-knockout reactions

Author

Lehr, C., Wamers, F., Aksouh, F., Aksyutina, Yu., Álvarez-Pol, H., Atar, L., Aumann, T., Beceiro-Novo, S., Bertulani, C.A., Boretzky, K., Borge, M.J.G., Caesar, C., Chartier, M., Chatillon, A., Chulkov, L.V., Cortina-Gil, D., Díaz Fernández, P., Emling, H., Ershova, O., Fraile, L.M., Fynbo, H.O.U., Galaviz, D., Geissel, H., Heil, M., Heine, M., Hoffmann, D.H.H., Holl, M., Johansson, H.T., Jonson, B., Karagiannis, C., Kiselev, O.A., Kratz, J.V., Kulessa, R., Kurz, N., Langer, C., Lantz, M., Le Bleis, T., Lemmon, R., Litvinov, Yu.A., Löher, B., Mahata, K., Marganiec-Galązka, J., Müntz, C., Nilsson, T., Nociforo, C., Ott, W., Panin, V., Paschalis, S., Perea, A., Plag, R., Reifarth, R., Richter, A., Riisager, K., Rodriguez-Tajes, C., Rossi, D., Savran, D., Scheit, H., Schrieder, G., Schrock, P., Simon, H., Stroth, J., Sümmerer, K., Tengblad, O., Weick, H., and Wimmer, C.

Published
2022
Full Text
View/download PDF

5. Safety and efficacy of ribociclib plus letrozole in patients with HR+, HER2– advanced breast cancer: Results from the Spanish sub-population of the phase 3b CompLEEment-1 trial.

Author

Salvador Bofill, Javier, Moreno Anton, Fernando, Rodriguez Sanchez, Cesar Augusto, Galve Calvo, Elena, Hernando Melia, Cristina, Ciruelos Gil, Eva Maria, Vidal, Maria, Jiménez-Rodriguez, Begoña, De la Cruz Merino, Luis, Martínez Jañez, Noelia, Villanueva Vazquez, Rafael, de Toro Salas, Ruben, Anton Torres, Antonio, Alvarez Lopez, Isabel Manuela, Gavila Gregori, Joaquin, Quiroga Garcia, Vanesa, Vicente Rubio, Elena, De la Haba-Rodriguez, Juan, Gonzalez-Santiago, Santiago, and Diaz Fernandez, Nieves

Subjects
HORMONE receptor positive breast cancer, METASTATIC breast cancer, EPIDERMAL growth factor receptors, OLDER patients, SPANIARDS
Abstract

Breast cancer is the most common malignancy and the second leading cause of cancer-related mortality in Spanish women. Ribociclib in combination with endocrine therapy (ET) has shown superiority in prolonging survival in patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2−) advanced breast cancer (ABC) vs. ET alone. CompLEEment-1 is a single-arm, open-label phase 3b trial evaluating ribociclib plus letrozole in a broad population of patients with HR+, HER2– ABC. The primary endpoints were safety and tolerability. Here we report data for Spanish patients enrolled in CompLEEment-1. A total of 526 patients were evaluated (median follow-up: 26.97 months). Baseline characteristics showed a diverse population with a median age of 54 years. At study entry, 56.5% of patients had visceral metastases and 8.7% had received prior chemotherapy for advanced disease. Rates of all-grade and Grade ≥3 adverse events (AEs) were 99.0% and 76.2%, respectively; 21.3% of patients experienced a serious AE, and 15.8% of AEs led to treatment discontinuation. AEs of special interest of neutropenia, increased alanine aminotransferase, increased aspartate aminotransferase and QTcF prolongation occurred in 77.8%, 14.8%, 11.4% and 4.0% of patients, respectively. Patients aged >70 years experienced increased rates of all-grade and Grade ≥3 neutropenia and anemia. Efficacy results were consistent with the global study. Results from Spanish patients enrolled in CompLEEment-1 are consistent with global data showing efficacy and a manageable safety profile for ribociclib plus letrozole treatment in patients with HR+, HER2− ABC, including populations of interest (NCT02941926). ClinicalTrials.gov NCT02941926 • Results from the CompLEEment-1 Spanish population are comparable to the global results. • Manageable safety was shown in elderly patients and those with visceral disease. • Efficacy data were comparable to those of the global study in a younger population. • Efficacy and safety of ribociclib are confirmed in a broader patient population. • Results confirm a robust response to treatment in a local setting. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

6. Probing the Z = 6 spin-orbit shell gap with (p,2p) quasi-free scattering reactions

Author

Syndikus, I., Petri, M., Macchiavelli, A.O., Paschalis, S., Bertulani, C.A., Aumann, T., Alvarez-Pol, H., Atar, L., Beceiro-Novo, S., Benlliure, J., Boillos, J.M., Boretzky, K., Borge, M.J.G., Brown, B.A., Caamaño, M., Caesar, C., Casarejos, E., Catford, W., Cederkall, J., Chakraborty, S., Chulkov, L.V., Cortina-Gil, D., Cravo, E., Crespo, R., Datta Pramanik, U., Dillmann, I., Díaz Fernández, P., Elekes, Z., Enders, J., Farinon, F., Fraile, L.M., Galaviz, D., Geissel, H., Gernhäuser, R., Golubev, P., Göbel, K., Heil, M., Heine, M., Heinz, A., Henriques, A., Holl, M., Johansson, H.T., Jonson, B., Kalantar-Nayestanaki, N., Kanungo, R., Kelic-Heil, A., Kröll, T., Kurz, N., Langer, C., Le Bleis, T., Machado, J., Marganiec-Gałązka, J., Nacher, E., Nilsson, T., Nociforo, C., Panin, V., Perea, A., Pietri, S.B., Plag, R., Rahaman, A., Reifarth, R., Revel, A., Ribeiro, G., Rigollet, C., Rossi, D.M., Savran, D., Scheit, H., Simon, H., Sorlin, O., Tengblad, O., Togano, Y., Vandebrouck, M., Volkov, V., Wamers, F., Wheldon, C., Wilson, G.L., Winfield, J.S., Weick, H., Woods, P., Yakorev, D., Zhukov, M., Zilges, A., and Zuber, K.

Published
2020
Full Text
View/download PDF

7. Study of Δ excitations in medium-mass nuclei with peripheral heavy ion charge-exchange reactions

Author

Rodríguez-Sánchez, J.L., Benlliure, J., Vidaña, I., Lenske, H., Scheidenberger, C., Vargas, J., Alvarez-Pol, H., Atkinson, J., Aumann, T., Ayyad, Y., Beceiro-Novo, S., Boretzky, K., Caamaño, M., Casarejos, E., Cortina-Gil, D., Díaz Fernández, P., Estrade, A., Geissel, H., Haettner, E., Kelić-Heil, A., Litvinov, Yu.A., Paradela, C., Pérez-Loureiro, D., Pietri, S., Prochazka, A., Takechi, M., Tanaka, Y.K., Weick, H., and Winfield, J.S.

Published
2020
Full Text
View/download PDF

8. Quasi-free neutron and proton knockout reactions from light nuclei in a wide neutron-to-proton asymmetry range

Author

Holl, M., Panin, V., Alvarez-Pol, H., Atar, L., Aumann, T., Beceiro-Novo, S., Benlliure, J., Bertulani, C.A., Boillos, J.M., Boretzky, K., Caamaño, M., Caesar, C., Casarejos, E., Catford, W., Cederkall, J., Chulkov, L., Cortina-Gil, D., Cravo, E., Dillmann, I., Díaz Fernández, P., Elekes, Z., Enders, J., Fraile, L.M., Galaviz Redondo, D., Gernhäuser, R., Golubev, P., Heftrich, T., Heil, M., Heine, M., Heinz, A., Henriques, A., Johansson, H.T., Jonson, B., Kalantar-Nayestanaki, N., Kanungo, R., Kelic-Heil, A., Kröll, T., Kurz, N., Langer, C., Le Bleis, T., Lindberg, S., Machado, J., Nacher, E., Najafi, M.A., Nilsson, T., Nociforo, C., Paschalis, S., Petri, M., Reifarth, R., Ribeiro, G., Rigollet, C., Rossi, D.M., Savran, D., Scheit, H., Simon, H., Sorlin, O., Syndikus, I., Tengblad, O., Togano, Y., Vandebrouck, M., Velho, P., Wamers, F., Weick, H., Wheldon, C., Wilson, G.L., Winfield, J.S., Woods, P., Zhukov, M., and Zuber, K.

Published
2019
Full Text
View/download PDF

10. Influencia de la depresión puerperal durante la hospitalización posparto en la lactancia materna.

Author

Mosteiro Diaz, M. Pilar, Fernandez Feito, Ana, Moran Ordonez, Debora, Amada Pellico Lopez, M., and Diaz Fernandez, Eugenia

Abstract

Presents a study which investigated the influence of depression during postpartum hospitalization in maternal lactation. Clinical characteristics of subjects; Prevalence of depressive disorders in the subjects; Situation which showed a higher instance of depression among lactating women.

Published
2001

Catalog

Books, media, physical & digital resources
See catalog results