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WLY-0, as an α -D-glucan with a molecular weight (Mw) of 11.12 kDa, was successfully isolated and purified from Huangshui (HS). The results of methylation and NMR indicated that the mainchain of WLY-0 was (1 → 4)- α -D-glucan, with side chains linking at O-6. Meanwhile, the surface morphology characterization showed that WLY-0 had an irregular flake-like morphology with a rough and uneven surface and varies in sizes from nanometers to microns. Furthermore, WLY-0 relieved the increased paracellular permeability of FD4 and decreased TEER challenged by LPS, meanwhile inhibited the production of pro-inflammatory cytokines (TNF- α , IL-6, and IL-1 β) and up-regulated the expression of TJ protein (Occludin, Claudin-1, ZO-1, and JAM-A) in Caco-2 cells, so to improve the intestinal barrier function. Our findings about the structural characteristics and biological activities of WLY-0 provided a scientific foundation for the utilization of HS as a potent source of an effective adjuvant in intestinal barrier injury treatment. [Display omitted] • A polysaccharide WLY-0 extracted from Huangshui , was identified as a α -D-glucan. • WLY-0 contains (1 → 4)- α -D-glucan in backbone, with side chains linking at O-6. • WLY-0 had an irregular flake-like morphology with a rough and uneven surface. • WLY-0 reversed LPS induced low TEER value and high FITC-dextran flux. • WLY-0 showed obvious intestinal barrier protective effect in vitro. [ABSTRACT FROM AUTHOR]

Cu and Mn co-doped LiNbO 3 films were deposited on Si (111) substrates by rf-magnetron sputtering. XRD shows a randomly oriented polycrystalline R3C structure of LiNbO 3 was formed in the films annealed at 1000 °C for 1 h in air. XPS and XAFS determine that Mn 2+ substitutes on the Li site with a Li vacancy and Cu 2+ substitutes on the Nb site with an oxygen vacancy in the LiNbO 3 lattice. SQUID measurements indicate that all the films exhibit room temperature ferromagnetism, attributed to a strong d–d electron interaction between Mn and Nb and the bound magnetic polarons resulting from the oxygen vacancies. The saturated magnetization increases but the atom magnetic moment decreases with increasing Cu content in the films. The drop of the atom magnetic moment may arise from the antiferromagnetic coupling among adjacent Cu ions and an antiparallel configuration between Cu 2+ ions and their trapped electrons. [ABSTRACT FROM AUTHOR]