Search

• Three H3N8 subtype low pathogenic avian influenza viruses were isolated from wild birds in China during the ordinary surveillance. • The H3N8 from wild birds in the study clustered with two emerged human H3N8 viruses in 2022 in the same Eurasian avian lineage. • The H3N8 from wild birds in the study presented dual receptors preferences. • The H3N8 from wild birds in the study replicated well in mammalian model without prior adaption. We present the phylogeny, receptor binding property, growth in mammal cells and pathogenicity in mammal model of H3N8 viruses, which were isolated from wild birds in China. The human receptor preference and efficient replication in mice without prior adaption highlight that the H3N8 virus possesses the public threat potential. [ABSTRACT FROM AUTHOR]

Triboelectric tactile sensing technique is increasingly coming into people's lives to bring convenience, so that there is an urgent necessity for this technique to be applied to smart mobility to increase safety and enhance the mobility experience. Herein, a single-electrode mode multilayer triboelectric sensor (MTS) motivated by artificial intelligence (AI) is proposed, which consists of styrene-butadiene-styrene (SBS)/ poly (vinylida-ene fluoride-trifluoroethylene) (PVDF-TrFE) nanofibers (NFs) film as the friction layer and substrate, laser-induced graphene (LIG)/molybdenum disulfide (MoS 2) as the charge trapping layer, and Ag as the electrode. The MTS exhibits remarkable sensing performance, such as a wide response range of 5–100 N, 0.4–2 Hz multi-frequency response capability, and non-contact sensing, as well as distinguished self-powered performance. To demonstrate the practical significance of the proposed MTS, two applications are explored specifically after equipping with AI, including: (i) a smart in-vehicle system is constructed, which consists of unlocking section and multifunctional control with early warning section. (ii) a smart car control system is implemented, which can carry out special tasks instead of humans. These applications provide reliable ways to promote the development of human-machine interaction and smart mobility, as well as help to make lifestyles and mobility smarter, safer and more convenient. [Display omitted] ● A single-electrode mode multilayer triboelectric sensor is developed with facile and cost-effective assembly process. ● The proposed sensor exhibits excellent sensing performance and demonstrates wonderful self-powered performance. ● Intelligent in-vehicle system integrates with music, GPS and warning functions are proposed. ● Combined with neural network, a smart car control system with directional control and intelligent perception is proposed. [ABSTRACT FROM AUTHOR]

Background: The risk factors for complete atrioventricular block (CAVB) after device closure of perimembranous ventricular septal defect (pmVSD) remain unclear.Objective: The purpose of this study was to analyze the incidence and risk factors for CAVB after device closure for pmVSD.Methods: We reviewed 1884 patients with pmVSD who had undergone successful device occlusion between June 2005 and January 2020. Permanent CAVB was defined as CAVB requiring implantation of a permanent pacemaker (PPM) or extraction of the occluder.Results: In total, 14 patients (0.7%) developed permanent CAVB. Of these patients, 10 (0.5%) required PPM implantation. Four permanent CAVB occurred within 7 days after the procedure (acute), 2 between 7 and 30 days (subacute), 3 between 30 days and 1 year (late), and 5 more than 1 year (very late). None of the subacute, late, and very late CAVB recovered normal conduction with medication and eventually required device removal or PPM implantation. Four patients with acute CAVB and 1 with subacute CAVB underwent device removal, and 4 (80%) recovered normal conduction. Multivariate regression revealed that the ratio of device to defect size was the only independent risk factor for permanent CAVB (odds ratio 3.027; 95% confidence interval 1.476-6.209; P = .003).Conclusion: The incidences of permanent CAVB after occlusion for pmVSD and PPM implantation were 0.7% and 0.5%, respectively. The ratio of device to defect size was the only independent risk factor for permanent CAVB. Device removal is an effective therapeutic modality for recovering normal conduction in acute and subacute CAVB patients. [ABSTRACT FROM AUTHOR]

Iridium-based bimetallic alloy system with unique performance is of great interest for high-temperature corrosive environment as a barrier layer or for water splitting of hydrogen/oxygen evolution reactions as a highly efficient and stable electrocatalyst. In this work, iridium-cobalt (Ir–Co) thin films were galvanostatically electrodeposited on a copper (Cu) foam electrode as an electrocatalyst for water splitting in 1.0 M KOH alkaline medium. The effects of loading and solution temperature on hydrogen evolution performance of Ir–Co deposits were investigated. The results show that Ir–Co deposits were adhered to substrates, with porous structure and hollow topography. The concentrations of Ir in the deposits with the loadings of 4.6, 3.2 and 0.8 mg·cm−2 were 88, 88 and 75 wt%, respectively. Ir–Co deposit with the loading of 3.2 mg·cm−2 required an overpotential of 108 mV for hydrogen evolution reaction to reach a current density of 30 mA cm−2, having a low Tafel slope value of 36 mV·dec−1. The changes in the solution temperature and catalyst loading had a significant effect on hydrogen evolution performance of Ir–Co/Ir–Co–O electrocatalysts. With the increasing of catalyst loading, the electrocatalytic activity increased firstly and then decreased. As the solution temperature was increased from 20 to 40 °C, the electrocatalytic activity of Ir–Co–O electrocatalyst increased, and then decreased with the rising of temperature. The apparent thermal activation energy obtained from Arrhenius plot was ~13.9 kJ mol−1. Ir–Co/Ir–Co–O deposits exhibited relatively good electrocatalytic stability and durability. The present work demonstrates a possible pathway to develop a highly active and durable substitute for thin film electrocatalysts for water splitting of hydrogen evolution reaction. Image 1 • Electrodeposition of Ir–Co thin film on copper foam as a high-performance HER electrocatalyst. • Ir–Co catalyst required η = 108 mV at j = 30 mA cm−2 with Tafel slope of 36 mV·dec−1. • Influence of temperature and loading on HER of Ir–Co/Ir–Co–O thin films on Cu foam. • Apparent thermal activation energy obtained from Arrhenius plot was about 13.9 kJ mol−1. • Electrodeposited Ir–Co thin films exhibited good electrocatalystic stability and durability. [ABSTRACT FROM AUTHOR]