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Start Over Author "Lu, Jing-Song" Publisher elsevier b.v.
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2. Bisindole alkaloids from Tabernaemontana corymbosa.

Author

Zhang, Bing-Jie, Lu, Jing-Song, Bao, Mei-Fen, Zhong, Xiu-Hong, Ni, Ling, Wu, Jing, and Cai, Xiang-Hai

Subjects
*ALKALOID synthesis, *TABERNAEMONTANA, *BIOACTIVE compounds, *X-ray diffraction, *CELL-mediated cytotoxicity
Abstract

Continued study in bioactive monoterpenoid alkaloids led to the isolation of nine undescribed alkaloids, taberyunines A-I, together with 32 known ones from the aerial parts of Tabernaemontana corymbosa Roxb. ex Wall (Apocynaceae). Among the undescribed alkaloids, taberyunines A-G and H-I were assigned to Aspidosperma-Aspidosperma and Vobasinyl-Ibogan type bisindoles, respectively. Their structures were determined by NMR spectra, MS data and X-ray diffraction. Taberyunine B showed significant cytotoxicity against three cancer cell lines. [ABSTRACT FROM AUTHOR]

Published
2018
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