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Abstract: Syntheses of 2,5-diarylthiazole and 2,5-diarylthiophene derivatives bearing ethynylene and thienylene spacers are performed. With the methods for coupling reactions of terminal alkynes and at the CH bond of heteroaromatic compounds, which we have developed, five kinds of thiazole and thiophene derivatives 3–7 are prepared. Spectroscopic characteristics of 3–7 are also measured. [Copyright &y& Elsevier]

Abstract: Sonogashira coupling with aqueous ammonia is tolerable for the reaction of aryl iodides or terminal alkynes bearing an azobenzene group. The reaction of (4-heptyloxyphenyl)ethyne with (4-heptyloxyphenyl)-(4-iodophenyl)diazene in the presence of 1mol% of PdCl2(PPh3)2, 2mol% of CuI, and 2equiv of 0.5M aqueous ammonia gives the corresponding azotolane in 87% isolated yield after stirring at room temperature for 15h. [Copyright &y& Elsevier]