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Your search keyword '"Paragomi, Pedram"' showing total 19 results
Start Over Author "Paragomi, Pedram" Publisher elsevier b.v.
19 results on '"Paragomi, Pedram"'

1. The relationship between pre-existing diabetes mellitus and the severity of acute pancreatitis: Report from a large international registry

Author

Paragomi, Pedram, Papachristou, Georgios I., Jeong, Kwonho, Hinton, Alice, Pothoulakis, Ioannis, Talukdar, Rupjyoti, Kochhar, Rakesh, Goenka, Mahesh K., Gulla, Aiste, Gonzalez, Jose A., Singh, Vikesh K., Ferreira Bogado, Miguel, Stevens, Tyler, Barbu, Sorin T., Nawaz, Haq, Gutierrez, Silvia C., Zarnescu, Narcis, Archibugi, Livia, Easler, Jeffrey J., Triantafyllou, Konstantinos, Peláez-Luna, Mario, Thakkar, Shyam, Ocampo, Carlos, de-Madaria, Enrique, Cote, Gregory A., Wu, Bechien U., Lee, Peter J., Hart, Phil A., Conwell, Darwin L., Toledo, Frederico G.S., and Yadav, Dhiraj

Published
2022
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3. Clinical features of hypertriglyceridemia-induced acute pancreatitis in an international, multicenter, prospective cohort (APPRENTICE consortium)

Author

Pothoulakis, Ioannis, Paragomi, Pedram, Archibugi, Livia, Tuft, Marie, Talukdar, Rupjyoti, Kochhar, Rakesh, Goenka, Mahesh Kumar, Gulla, Aiste, Singh, Vikesh K., Gonzalez, Jose A., Ferreira, Miguel, Barbu, Sorin T., Stevens, Tyler, Nawaz, Haq, Gutierrez, Silvia C., Zarnescu, Narcis O., Easler, Jeffrey, Triantafyllou, Konstantinos, Pelaez-Luna, Mario, Thakkar, Shyam, Ocampo, Carlos, de-Madaria, Enrique, Wu, Bechien U., Cote, Gregory A., Tang, Gong, Papachristou, Georgios I., and Capurso, Gabriele

Published
2020
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4. Incident diabetes following acute pancreatitis in a multicenter prospective observational cohort.

Author

Bejjani, Joseph, Papachristou, Georgios I., Dungan, Kathleen, Evans Phillips, Anna, Singh, Vikesh, Toledo, Frederico GS., Han, Samuel, Krishna, Somashekar G., Lahooti, Ali, Lee, Peter J., Machicado, Jorge D., Nikahd, Melica, Paragomi, Pedram, Ramsey, Mitch, Yadav, Dhiraj, Culp, Stacey, and Hart, Phil A.

Abstract

Diabetes mellitus following an episode of acute pancreatitis (AP) is an increasingly discussed complication, but there are sparse prospective data on the incidence and risk factors. We evaluated data from a prospective, multicenter observational cohort study that enrolled adults hospitalized with AP between 2017 and 2021 and followed them for one year. Ninety-eight participants who completed 12-month follow-up were included in this analysis. Diabetes status was assessed using a combination of measured glycated hemoglobin (HbA1c) at predetermined time intervals or physician diagnosis. In 68 participants without diabetes at enrollment, the cumulative incidence of new-onset diabetes was 4.4 % (n = 3) at 3 months and 10.3 % (n = 7) at 12 months. No differences were observed in demographic or pancreatitis-related characteristics between those who did versus did not develop diabetes, in part due to small sample size. In summary, new-onset diabetes was identified in approximately 10 % within one year after an episode of AP. Larger prospective studies are needed to further define the incidence, risk factors, and mechanisms of diabetes and pre-diabetes following AP. NCT03063398. [ABSTRACT FROM AUTHOR]

Published
2023
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8. Hypertriglyceridemia-induced acute pancreatitis: features from a global cohort study (APPRENTICE)

Author

Archibugi, Livia, Pothoulakis, Ioannis, Paragomi, Pedram, Tuft, Marie, Talukdar, Rupiyoti, Kochar, Rakesh, Goenka, Mahesh Kumar, Gulla, Aiste, Singh, Vikesh K., Gonzalez, Jose A., Ferreira, Miguel, Barbu, Sorin T., Stevens, Tyler, Nawaz, Haq, Gutierrez, Silvia, Zarnescu, Narcis, Easler, Jeffrey, Triantafyllou, Konstantinos, Pelaez-Luna, Mario, Thakkar, Shyam, Ocampo, Carlos, de-Madaria, Enrique, Wu, Bechien, Cote, Gregory A., Tang, Gong, Papachristou, Georgios I., and Capurso, Gabriele

Published
2019
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9. Persistent SIRS and non-alcohol etiology of AP are associated with oral feeding intolerance in AP: Results from an international, multicenter, prospective cohort study

Author

Phillips, Anna, Pothoulakis, Ioannis, Paragomi, Pedram, Jeong, Kwonho, Ooka, Kohtaro, Talukdar, Rupiyoti, Kochar, Rakesh, Goenka, Mahesh Kumar, Kielaitė-Gulla, Aiste, Singh, Vikesh, Gonzalez, Jose, Ferreira, Miguel, Barbu, Sorin T., Stevens, Tyler, Gutierrez, Silvia, Zarnescu, Narcis, Capurso, Gabriele, Easler, Jeffrey, Triantafyllou, Konstantinos, Pelaez-Luna, Mario, Thakkar, Shyam, Ocampo, Carlos, de-Madaria, Enrique, Wu, Bechien, Cote, Gregory, Papachristou, Georgios, and Nawaz, Haq

Published
2019
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10. Can PASS activity index be utilized around the world? Results from a multi-center, international, prospective cohort in acute pancreatitis

Author

Phillips, Anna, Paragomi, Pedram, Pothoulakis, Ioannis, Tuft, Marie, Gougol, Amir, Talukdar, Rupiyoti, Kochar, Rakesh, Goenka, Mahesh Kumar, Kielaitė-Gulla, Aiste, Singh, Vikesh, Gonzalez, Jose, Ferreira, Miguel, Barbu, Sorin T., Stevens, Tyler, Nawaz, Haq, Gutierrez, Silvia, Zarnescu, Narcis, Capurso, Gabriele, Easler, Jeffrey, Triantafyllou, Konstantinos, Pelaez-Luna, Mario, Thakkar, Shyam, Ocampo, Carlos, de-Madaria, Enrique, Cote, Gregory, Wu, Bechien, Greer, Phil J., Tang, Gong, and Papachristou, Georgios

Published
2019
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14. The Modified Pancreatitis Activity Scoring System Shows Distinct Trajectories in Acute Pancreatitis: An International Study.

Author

Paragomi, Pedram, Hinton, Alice, Pothoulakis, Ioannis, Talukdar, Rupjyoti, Kochhar, Rakesh, Goenka, Mahesh K., Gulla, Aiste, Gonzalez, Jose A., Singh, Vikesh K., Bogado, Miguel Ferreira, Stevens, Tyler, Barbu, Sorin T., Nawaz, Haq, Gutierrez, Silvia C., Zarnescu, Narcis, Archibugi, Livia, Easler, Jeffrey J., Triantafyllou, Konstantinos, Peláez-Luna, Mario, and Thakkar, Shyam

Abstract

The aims of this study were to: (1) assess the performance of the Pancreatitis Activity Scoring System (PASS) in a large intercontinental cohort of patients with acute pancreatitis (AP); and (2) investigate whether a modified PASS (mPASS) yields a similar predictive accuracy and produces distinct early trajectories between severity subgroups. Data was prospectively collected through the Acute Pancreatitis Patient Registry to Examine Novel Therapies In Clinical Experience (APPRENTICE) consortium (2015-2018) involving 22 centers from 4 continents. AP severity was categorized per the revised Atlanta classification. PASS trajectories were compared between the three severity groups using the generalized estimating equations model. Four mPASS models were generated by modifying the morphine equivalent dose (MED), and their trajectories were compared. A total of 1393 subjects were enrolled (median age, 49 years; 51% males). The study cohort included 950 mild (68.2%), 315 (22.6%) moderately severe, and 128 (9.2%) severe AP. Mild cases had the lowest PASS at each study time point (all P <.001). A subset of patients with outlier admission PASS values was identified. In the outlier group, 70% of the PASS variation was attributed to the MED, and 66% of these patients were from the United States centers. Among the 4 modified models, the mPASS-1 (excluding MED from PASS) demonstrated high performance in predicting severe AP with an area under the receiver operating characteristic curve of 0.88 (vs area under the receiver operating characteristic of 0.83 in conventional PASS) and produced distinct trajectories with distinct slopes between severity subgroups (all P <.001). We propose a modified model by removing the MED component, which is easier to calculate, predicts accurately severe AP, and maintains significantly distinct early trajectories. [ABSTRACT FROM AUTHOR]

Published
2022
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15. 798: RACE, PRE-EXISTING LUNG DISEASE, AND ETIOLOGY ARE ASSOCIATED WITH RISK FOR MULTISYSTEM ORGAN FAILURE IN ACUTE PANCREATITIS: AN INTERNATIONAL, MULTI-CENTER, OBSERVATIONAL STUDY.

Author

Lahooti, Ali, Boutsicaris, Andrew, Holovach, Phillip, Wozniak, Kayla, Subramanian, Tejas, Lahooti, Ila, Paragomi, Pedram, Jeong, Kwonho, Hinton, Alice, Pothoulakis, Ioannis, Talukdar, Rupjyoti, Kochhar, Rakesh, Goenka, Mahesh K., Gulla, Aiste, Gonzalez, Jose A, Singh, Vikesh, Bogado, Miguel Ferreira, Stevens, Tyler, Babu, Sorin T., and Nawaz, Haq

Published
2022
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19. Rapid antidepressant effects of repeated doses of ketamine compared with electroconvulsive therapy in hospitalized patients with major depressive disorder.

Author

Ghasemi, Mehdi, Kazemi, Mohammad H., Yoosefi, Abolghasem, Ghasemi, Abbas, Paragomi, Pedram, Amini, Homayoun, and Afzali, Mohammad H.

Subjects
*MENTAL depression, *THERAPEUTICS, *ANTIDEPRESSANTS, *KETAMINE, *ELECTROCONVULSIVE therapy, *PEOPLE with mental illness, *CARE of people, *PSYCHOTHERAPY, *TREATMENT effectiveness
Abstract

Abstract: Accumulating evidence suggests that N-methyl-d-aspartate receptor (NMDAR) antagonists (e.g. ketamine) may exert rapid antidepressant effects in MDD patients. In the present study, we evaluated the rapid antidepressant effects of ketamine compared with the electroconvulsive therapy (ECT) in hospitalized patients with MDD. In this blind, randomized study, 18 patients with DSM-IV MDD were divided into two groups which received either three intravenous infusions of ketamine hydrochloride (0.5mg/kg over 45min) or ECT on 3 test days (every 48h). The primary outcome measure was the Beck Depression Inventory (BDI) and Hamilton Depression Rating Scale (HDRS), which was used to rate overall depressive symptoms at baseline, 24h after each treatment, 72h and one week after the last (third) ketamine or ECT. Within 24h, depressive symptoms significantly improved in subjects receiving the first dose of ketamine compared with ECT group. Compared to baseline level, this improvement remained significant throughout the study. Depressive symptoms after the second dose ketamine was also lower than the second ECT. This study showed that ketamine is as effective as ECT in improving depressive symptoms in MDD patients and have more rapid antidepressant effects compared with the ECT. [Copyright &y& Elsevier]

Published
2014
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