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Synthesis of the isomers of deoxy spiro carbon linked disaccharides has been reported. But-3-yn-1-ol has been utilised as a four carbon conjunctive reagent for the C&z.sbnd;C bond formation and was later stereoselectively converted into cis and trans olefins for further elaboration into the deoxy sugar moiety through cis dihydroxylation. [Copyright &y& Elsevier]

A facile and mild protocol for the synthesis of substituted tetrahydrofurans, 2-deoxy C-aryl glycoside and C-aryl glycosides is described by use of 20 mol% FeCl3 or Yb(OTf)3 as acid catalysts. The benzylic carbocation generated undergoes intramolecular substitution by the oxygen nucleophile to result the tetrahydrofurans and C-aryl glycosides. [Copyright &y& Elsevier]

A mild and efficient route to glycosyl β-amino acid esters, exploiting the stereoselective Michael addition of benzylamine, in the presence of tetra-n-butylammonium fluoride, to sugar derived γ-alkoxy α,β-unsaturated esters is described. [Copyright &y& Elsevier]

The total synthesis of macrolide antibiotics, macrosphelide A and E has been achieved starting from carbohydrate precursors. [Copyright &y& Elsevier]

d- and l-glycero-C-Phenyl heptopyranosides 1, 2 and 3 are synthesized for the first time from (R)-glyceraldehyde and l-ascorbic acid derivatives. The main strategy involves intramolecular nucleophilic substitution and double bond functionalisation. [Copyright &y& Elsevier]