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To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.amjmed.2008.10.037 Byline: David L. Greenburg (a)(b), Christopher J. Lettieri (c), Arn H. Eliasson (c) Keywords: Bariatric surgery; Meta-analysis; Obesity; Obstructive sleep apnea Abstract: Limited evidence suggests bariatric surgery can result in high cure rates for obstructive sleep apnea (OSA) in the morbidly obese. We performed a systematic review and meta-analysis to identify the effects of surgical weight loss on the apnea-hypopnea index. Author Affiliation: (a) Department of Medicine, Walter Reed Army Medical Center, Washington, DC (b) Department of Medicine, Madigan Army Medical Center, Fort Lewis, Washington (c) Department of Pulmonary and Sleep Medicine, Walter Reed Army Medical Center, Washington, DC Article Note: (footnote) Funding: None., Conflict of Interest: All authors are employees of the Department of Defense. Expressed opinions represent those of the authors and do not represent those of the Department of Defense., Authorship: All authors had access to the data and played a role in writing this manuscript.

Whether computerized autoadjusted continuous positive airway pressure (aCPAP)is effective or even superior to constant continuous positive airway pressure (cCPAP) in the treatment of obstructive sleep apnea syndrome (OSAS) is still [...]

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ajo.2004.11.004 Byline: Raed Behbehani (a), Michaela K. Mathews (a), Robert C. Sergott (a), Peter J. Savino (a) Abstract: To report three cases of nonarteritic anterior ischemic optic neuropathy (NAION) that occurred in patients with sleep apnea syndrome (SAS) while being treated with continuous positive airway pressure (CPAP). Author Affiliation: (a) Neuroophthalmology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania Article History: Accepted 28 June 2004

Study objective: To evaluate the tolerability and to find predictors of treatment success for all individually adjusted, one-piece mandibular advancement device in patients with snoring and obstructive sleep apnea. Design.: [...]

Objective: Obstructive sleep apnea (OSA) has been shown to affect the quality of life (QOL) in patients, and QOL improves after treatment with nasal continuous positive airway pressure (CPAP). However, [...]

Study objectives: The effectiveness of nasal continuous positive airway pressure (CPAP) in treating obstructive sleep apnea (OSA) is based on raising the intramural pressure above a critical collapsing pressure of [...]

Study objectives: To determine the short-term and long-term impacts of continuous positive airway pressure (CPAP) therapy on health-related quality of life (HRQL) in patients with obstructive sleep apnea (OSA). Design: [...]

Study objective: This study was designed to determine whether different desaturation indexes (DIs) would be obtained in patients with sleep-disordered breathing by systematically altering two acquisition parameters: the recording setting [...]

Objectives: To compare BP response to 3 weeks of nasal continuous positive airway pressure (CPAP) in hypertensive patients with and without sleep-disordered breathing (SDB). Design: A controlled, interventional trial of [...]

Study objective: To compare the results of a two-point palatal discrimination response in normal subjects (n = 15), patients with obstructive sleep apnea syndrome (OSAS) [n = 15], and patients [...]

There is measure in all things. 'Satires' Book 1, Horace Horace was certainly not referring to sleep apnea hypopnea syndrome (SAHS) when he composed this well-known aphorism, even though there [...]

Background: For the treatment of nonsevere obstructive sleep apnea syndrome (OSAS), mandibular advancement devices (MADs) are employed as an alternative to nasal continuous positive airway pressure (CPAP) therapy. However, very [...]

Study objectives: To evaluate the relationship between sleep structure and continuous positive airway pressure (CPAP) delivered by an automatic CPAP (auto-CPAP) machine in patients with obstructive sleep apnea syndrome (OSAS). [...]

Study objectives: To evaluate the effects of treatment with a dental appliance or uvulopalatopharyngoplasty (UPPP) on somnographic variables in patients with mild-to-moderate obstructive sleep apnea (OSA) followed up for 4 [...]

Obstructive sleep apnea (OSA) has in recent years assumed a somewhat more notorious prominence in the lay press and in the medical literature. With a prevalence of 2 to 4% [...]

Study objectives: To determine long-term compliance rates to continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnea enrolled in a comprehensive CPAP program in the community. Design: [...]

Objectives: (1) [T.sub.0] compare the continuous positive airway pressure (CPAP) requirement at the time of diagnosis ([T.sub.0]), after 2 weeks ([T.sub.2]), and after 4 weeks ([T.sub.4]) of CPAP treatment, in [...]

Objective: Continuous positive airway pressure (CPAP) is the treatment of choice for patients diagnosed with severe obstructive sleep apnea (OSA). The implementation of CPAP therapy has traditionally been based on [...]

Objectives: To assess whether an initial treatment with nasal continuous positive airway pressure (NCPAP) therapy, applied for one night, had any effect on airway patency. Methods: In 18 patients with [...]

Twenty-four patients who failed uvulopalatopharyngoplasty (UPPP) for obstructive sleep apnea (OSA) had an adjustable oral (Herbst) appliance made to treat the persistent apnea. Six patients discontinued the device prior to [...]

Objective: To evaluate the effects of a mandibular advancement device on apneas and sleep in mild, moderate, and severe obstructive sleep apnea. Design: Prospective study. Subjects: Forty-four of 47 patients [...]

Many studies have shown a relationship between obstructive sleep apnea (OSA) and accidents but to our knowledge, none have investigated prospectively the effects of treatment with nasal continuous positive airway [...]

Study objective: This study aimed to evaluate the effects of nasal continuous positive airway pressure (nCPAP) therapy on sleep and daytime symptoms of bed partners and patients with obstructive sleep [...]

Study objectives: To determine an effective means of improving compliance with nasal continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA). Design: Retrospective chart review. Setting: An outpatient clinic [...]

Purpose: Oral appliances (OAs) are used to treat obstructive sleep apnea (OSA). This study seeks to quantify the patterns of practice of OA use among dentists. Design: Survey mailed to dentists. Participants: Members of the Sleep Disorders Dental Society (SDDS). Measurements: Dentists were asked questions regarding number of patients treated, types of OA used, average total OA cost to the patient excluding reimbursement, percentages of patients receiving pretreatment and posttreatment nocturnal polysomnography (NPSG), and whether they believe subjective patient reports alone or nocturnal pulse oximetry alone is an adequate substitute for NPSG to assess OSA treatment response. Summary statistics for the absolute value and percentage data are presented with the median, maximum, and minimum range. Results: Three hundred fifty-five surveys were mailed, of which 124 (35%) were returned. These dentists treat a median of 27 OSA patients with OAs (range, 2 to 300) annually. Patients receive pretreatment NPSG in 95% of cases (range, 0 to 100%), and posttreatment NPSG in 18% of cases (range, 0 to 100%). Only 7% of dentists believe subjective patient reports alone are an adequate substitute for NPSG. Nocturnal pulse oximetry was perceived to be an adequate substitute for NPSG by 37%. Dentists who believe nocturnal pulse oximetry to be an adequate substitute for posttreatment NPSG are less likely to obtain pretreatment or posttreatment NPSG (Mann-Whitney U test, two-tailed; p=0.001, p=0.02). Conclusions: Most SDDS dentists believe subjective reports and nocturnal pulse oximetry are inadequate to assess OA treatment response in OSA patients, yet posttreatment PSG is obtained infrequently. (CHEST 1997;111:382-86) Key words: dentists; obstructive sleep apnea; oral appliance; polysomnography Abbreviations: ASDA=American Sleep Disorders Association; CPAP=continuous positive airway pressure; NPSG=noeturnal polysomnography; OA=oral appliance; OSA=obstructive sleep apnea; RDI=respiratory disturbance index; SDDS=Sleep Disorders Dental Society, The prevalence of obstructive sleep apnea (OSA), as defined by a respiratory disturbance index (RDI) of [is greater than or equal to] 15 events per hour on nocturnal polysomnography (NPSG), [...]

Objective: To examine the effect of oxygen on apneas and sleep quality in patients with frequent central apneas during sleep. Design/subjects: Prospective intervention study of 20 consecutive patients with predominant [...]

Study objective: To assess separately the effectiveness and safety of nasal-continuous positive airway pressure (N-CPAP) and that of surgery in comparison to conservative management in patients with obstructive sleep apnea [...]

The benefits of continuous positive airway pressure (CPAP) therapy in patients with the sleep apnea/hypopnea syndrome (SAHS) are poorly documented and patients use CPAP less than physicians recommend. To establish [...]

Objective: This study compared the efficacy of a removable anterior mandibular positioning (AMP) device to continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) using a fully [...]

Treatment of obstructive sleep apnea (OSA) has developed over the last 25 years from tracheostomy to a variety of options, including weight loss, nasal continuous positive airway pressure (N-CPAP), pharyngeal [...]

Study objective: To compare efficacy, side effects, patient compliance, and preference between oral appliance (OA) therapy and nasal-continuous positive airway pressure (N-CPAP) therapy. Design: Randomized, prospective, crossover study. Setting: University [...]

Study rationale and objective. Sleep-disordered breathing is commonly treated with nasally applied continuous positive airway pressure (CPAP). Typically, pressures are titrated to pneumatically splint the airway to prevent its collapse [...]

Study objective: To determine whether alterations of platelet reactivity occur during obstructive sleep apnea (OSA) and, if so, whether therapy with nasal-continuous positive airway pressure (N-CPAP) alters this reactivity. Design: [...]

Habitual snoring is associated with an increased prevalence of hypertension, stroke, and ischemic heart disease. To determine factors that influence the incidence and remission of habitual snoring, we analyzed responses [...]

Objective: We sought to find a combination of noninvasive treatments for snoring by adding weight loss to previously studied treatments, including the combination of sleeping on one's side and using [...]

Patients with severe obstructive sleep apnea polygraphically documented underwent electrical stimulation treatment trials. Submental and intraoral stimulations were applied during waking and during nocturnal sleep. The stimulation was applied using [...]

We studied 107 patients with sleep-disordered breathing to confirm the effectiveness of continuous positive airway pressure (CPAP) titration using a split-night protocol. Patients spent two consecutive nights in our laboratory [...]

The effect of continuous positive airway pressure (CPAP) applied via a mask covering the nose and mouth (oralnasal CPAP = ONCPAP) on obstructive sleep apnea (OSA) was studied in ten [...]

Although nasal continuous positive airway pressure (CPAP) is effective in the treatment of most patients with obstructive sleep apnea (OSA), there is a small group of such patients in whom [...]

The long-term acceptability of treatment with nasal continuous positive airway pressure (CPAP) was studied prospectively in 44 patients with obstructive sleep apnea syndrome. At 14 months on the average after [...]

Patients with obstructive sleep apnea (OSA) have decreased long-term survival. Treatment of OSA with either nasal continuous positive airway pressure (CPAP) or tracheostomy improves survival, but the effect of uvulopalatopharyngoplasty [...]

Nasal continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) is usually titrated in a sleep laboratory with full polysomnographic monitoring until apneas, nonapneic desaturation, snoring, and micro-arousals are eliminated. This titration is sometimes done in the second half of the diagnostic sleep study or commonly on a separate second full night in the sleep laboratory. We performed NCPAP titration in the home in 17 patients with OSA previously documented by full polysomnography. Nasal CPAP was titrated at night in the patient's home by a registered nurse or polysomnography technician monitoring real-time recordings of heart rate, thoracic impedance, oxygen saturation, and pressure at the nasal mask on a four-channel recorder (EdenTec, Eden Prairie, Minn). Recordings of the nasal CPAP titration night were reviewed later by a physician. Apneas, hypopneas, and snoring were successfully eliminated in all patients. Mean nasal CPAP pressure was 10.3 ± 3.2 cm [H.sub.2]O. At the time of a follow-up interview, 13 of 17 patients continued to be compliant with nasal CPAP therapy. The mean duration of therapy was 13.4 ± 11.7 months with 7.23 mean hours of use for 6.76 nights per week. This compliance compares favorably with long-term home nasal CPAP compliance previously reported in patients titrated in our sleep laboratory. Home nasal CPAP titration resulted in about a $600 savings per patient. (Chest 1993; 104:1707-10) AHI = apnea/hypopnea index; CPAP = continuous positive airway pressure; OSA = obstructive sleep apnea, Nasal continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA) is usually prescribed after a sleep laboratory study where full polysomnographic monitoring is performed to determine the effective [...]

Unattended four-channel sleep apnea recording has been shown to be an accurate tool in the diagnosis of moderate to severe obstructive sleep apnea. We selected 11 patients with severe obstructive [...]

To estimate reliability of self-reported compliance with nasal continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA), we studied 63 OSA patients aged 53.7 ± 1.2 years (mean [...]