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Start Over Author "Yang, Yuqi" Publisher elsevier b.v.
145 results on '"Yang, Yuqi"'

22. The emergence of cancer sono-immunotherapy.

Author

Yang, Yuqi, Cheng, Yuan, and Cheng, Liang

Subjects
*CELL death, *DRUG side effects, *REACTIVE oxygen species, *TUMOR microenvironment, *THERMAL batteries, *CANCER cells
Abstract

Under appropriate parameters, medical ultrasound can induce immunogenic cell death via thermal and/or nonthermal effects, activating a certain degree of antitumor immunity in cancer mouse models. Different types of sono-responsive biomaterials have been coupled to immunomodulators, which can be released into the tumor microenvironment under ultrasonic irradiation. Systems that integrate sonosensitizers and immunologically active agents generating reactive oxygen species can result in a combined therapeutic effect upon ultrasound exposure in certain cancer mouse models. Following ultrasound treatment, certain engineered bacterial or cellular approaches can trigger antitumor immune responses in certain cancer mouse models. Current cancer immunotherapy suffers from limited response rates, variable efficacies, and immune-related adverse events. One alternative strategy is to use emerging sono-immunotherapeutic approaches via biomedical ultrasound, which can serve as a switch to induce direct therapy as well as further antitumor immune responses. Understanding the process of sono-immunomodulation and the potencies of several novel strategies based on sono-immunomodulatory agents can accelerate the development and transformation of immunotherapy for certain cancers and, ideally, for other diseases. Owing to its remarkable ease of use, ultrasound has recently been explored for stimulating or amplifying immune responses during cancer therapy, termed 'sono-immunotherapy'. Ultrasound can cause immunogenic cell death in cancer cells via thermal and nonthermal effects to regulate the tumor microenvironment, thereby priming anticancer immunity; by integrating well-designed biomaterials, novel sono-immunotherapy approaches with augmented efficacy can also be developed. Here, we review the advances in sono-immunotherapy for cancer treatment and summarize existing limitations along with potential trends. We offer emerging insights into this realm, which might prompt breakthroughs and expand its potential applications to other diseases. [ABSTRACT FROM AUTHOR]

Published
2024
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45. CuInS2-based photocatalysts for photocatalytic hydrogen evolution via water splitting.

Author

Yang, Yuqi, Zheng, Xinlong, Song, Yiming, Liu, Yuhao, Wu, Daoxiong, Li, Jing, Liu, Weifeng, Fu, Lirong, Shen, Yijun, and Tian, Xinlong

Subjects
*PHOTOCATALYSTS, *SEMICONDUCTOR materials, *MELTING points, *COPPER sulfide, *HYDROGEN, *SOLAR cells
Abstract

The realization of efficient photocatalytic hydrogen evolution (PHE) significantly depends on the development of durable and effective semiconductor photocatalysts. Copper indium sulfide (CuInS 2) is an emerging ternary chalcogenide semiconductor material for solar-to-chemical energy application, because it possesses a suitable bandgap, environment-friendly elements, and a low melting point. CuInS 2 -based semiconductor photocatalysts have been investigated for PHE via water splitting, but current PHE performance still has difficulty in meeting commercial application requirements and needs to be further improved. In this review, the basic semiconductor properties of CuInS 2 , including its crystal and band structures, are introduced, and its PHE mechanism is discussed in detail. The PHE performance of CuInS 2 -based photocatalysts is systematically discussed, with a focus on morphology, engineered structure, and heterojunction construction. Finally, issues and challenges currently encountered in the PHE application of CuInS 2 -based photocatalysts and their possible solutions are presented. [Display omitted] • The article focuses on photocatalytic hydrogen evolution (PHE) using CuInS 2 as photocatalyst. • Semiconductor properties of CuInS 2 is suitable for efficient PHE. • The strategies that enhance PHE rate of CuInS 2 are summarized. • Limitations and future prospects of CuInS 2 -based photocatalysts have also been reviewed. [ABSTRACT FROM AUTHOR]

Published
2023
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