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Start Over Author "You, Yu" Publisher elsevier b.v.
167 results on '"You, Yu"'

24. Interplay of irradiation-induced defects with oxygen in 3C-SiC ceramics.

Author

Sun, Jingjing, You, Yu-Wei, Zhang, Linhui, Hu, Wencheng, Li, B.S., and Liu, C.S.

Subjects
*NUCLEAR energy, *CERAMICS, *OXYGEN, *ENERGY policy, *FULLERENES, *BINDING energy
Abstract

The oxidation behavior of SiC ceramics is vital to assess its lifetime under extreme conditions within nuclear power systems. Employing systematic first-principles calculations, we studied the oxygen (O) properties in 3C-SiC without and with irradiation-induced defects to understand the oxidation mechanism. Interstitial O (O i n t) exhibits two energetically favored states with an energy difference of only 0.02 eV. Two O i n t atoms have a strong mutual attraction, with a binding energy reaching 0.80 eV. The stability of O-related defects with charge was investigated. The formation energy of O at the carbon site (O C) is negative, implying that the dissolution of O in the host carbon site is exothermic. The binding strengths of O i n t and O C with irradiation-induced defects are notably high. The formation energies of O and carbon vacancy clusters (V C m O n) decrease approximately linearly and turn negative as the number of O increases. The binding energy of V C m O n is still very high, indicating a strong attraction between them. Furthermore, Trapping of O by carbon vacancies may reduce the mobility of O. Electronic properties are analyzed to reveal the interaction mechanism between irradiation-induced defects and O. The irradiation-induced defects may enhance the oxidation of SiC due to the strong binding energies. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Upper-Neck Versus Whole-Neck Irradiation at the Contralateral Uninvolved Neck in Patients With Unilateral N3 Nasopharyngeal Carcinoma.

Author

Huang, Cheng-Long, Qiu, You-Yu, Du, Xiao-Jing, Wang, Gao-Yuan, Guo, Rui, Zhou, Guan-Qun, Liu, Na, Liu, Xu, Mao, Yan-Ping, Sun, Ying, Ma, Jun, and Tang, Ling-Long

Subjects
*NASOPHARYNX cancer, *NECK, *SURVIVAL rate, *DISEASE relapse, *IRRADIATION
Abstract

Upper-neck irradiation (UNI) at the uninvolved neck has shown similar regional relapse–free survival as standard whole-neck irradiation (WNI) in patients with N0-1 nasopharyngeal carcinoma. However, whether UNI at the contralateral uninvolved neck is feasible in unilateral N3 disease, defined as >6 cm and/or below the caudal border of the cricoid cartilage, remains unclear. Data for 291 patients with nasopharyngeal carcinoma with unilateral N3 disease who were treated with intensity modulated radiation therapy from 2009 to 2015 were retrospectively analyzed. Among them, 190 received bilateral WNI (WNI group); the remaining 101 received WNI at the involved neck and UNI at the contralateral uninvolved neck (UNI group). Survival rates were estimated using the Kaplan-Meier method, and differences between groups were compared using the log rank tests. The median follow-up was 79.4 months (interquartile range, 56.0-89.3). Twenty-five patients had regional lymph node relapses (UNI: 10.9%, 11/101 vs WNI: 7.4%, 14/190; P =.31). Of these, 23 patients relapsed within the previously involved neck regions, while only 2 patients had relapses in the contralateral uninvolved neck (1 each in the UNI and WNI groups). Five-year regional relapse–free survival rates were similar between groups (89.7% vs 92.7%, P =.29). Similar between-group findings were also observed for 5-year overall survival (76.1% vs 80.4%, P =.40), distant metastasis–free survival (74.9% vs 79.2%, P =.44), and local relapse–free survival (95.6% vs 94.7%, P =.64). Furthermore, oncologic outcomes in subgroup and multivariable analyses were similar between groups. Regional control and survival outcomes were comparable in UNI at the contralateral uninvolved neck and standard WNI in patients with nasopharyngeal carcinoma with unilateral N3 disease. Our findings provide evidence for future radiation therapy guidelines of nasopharyngeal carcinoma. [ABSTRACT FROM AUTHOR]

Published
2023
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