1. Comparison of Cobas® HPV and Anyplex™ II HPV28 assays for detecting and genotyping human papillomavirus.
- Author
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Pasquier C, Sauné K, Raymond S, Boisneau J, Courtade M, and Izopet J
- Subjects
- Adult, Aged, Female, Humans, Middle Aged, Papillomaviridae genetics, Young Adult, Genotyping Techniques methods, Molecular Diagnostic Techniques methods, Papillomaviridae classification, Papillomaviridae isolation & purification, Papillomavirus Infections diagnosis, Papillomavirus Infections virology
- Abstract
Persistent infection with high-risk human papillomavirus (HPV-HR) is a recognized cause of cervical cancer. The aim of this study was to compare analytical and clinical performances of the Cobas® HPV and Anyplex™ II HPV28 assays for HPV detection and genotyping. A total of 94 cervical samples were tested. For HPV-HR, the results agreed very well (94.68%), with 100% agreement when detecting CIN2+. The Anyplex™ II HPV28 assay detected more genotypes than the Cobas® HPV Test, but their clinical performances were similar., (Copyright © 2016. Published by Elsevier Inc.)
- Published
- 2017
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