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Resume Introduction A l’heure ou la problematique de consentement en matiere de relations sexuelles fait l’objet de debats passionnes, il convient de se pencher sur les violences sexuelles commises dans un contexte conjugal. Objectifs Cette etude vise d’abord a evaluer les caracteristiques sociodemographiques, situationnelles, criminologiques et psychologiques d’auteurs de violences conjugales ayant commis des violences sexuelles contre leur conjointe (n = 27) et d’auteurs de violences conjugales n’ayant pas commis de violences sexuelles contre leur conjointe (n = 76). Le second objectif de l’etude est d’identifier les variables predictives des violences conjugales sexuelles. Methode Les caracteristiques de ces hommes ont ete evaluees a partir d’entrevues semi-dirigees et de questionnaires portant sur certains enjeux psychologiques (alexithymie, depression et impulsivite) et aux evenements de vie stressants. Resultats Les resultats indiquent qu’il y a significativement plus d’auteurs de violences conjugales incluant la violence sexuelle qui sont sans emploi et qui presentent une consommation abusive d’alcool et/ou de drogue. De plus, ces hommes montrent un risque accru d’antecedents criminels commis dans les cinq dernieres annees ainsi que de commettre des violences de plusieurs formes, autant verbales, psychologiques, physiques et economiques. Conclusion Une meilleure distinction entre les differents profils d’auteurs de violences au sein du couple contribue a favoriser leur evaluation et, par le fait meme, a la prevention des violences conjugales severes.

It has been reported that injection of the antitumoral drug cis -dichlorodiammineplatinum at 10 days of life affects cerebellar development in rats. After a single dose of 5 μg/g of body weight, the formation of granule cells is decreased and the maturation of postmitotic neurons is slowed down. A substantial time after treatment, reduced cell packing density of the internal granule layer and atrophy of the molecular layer can be observed. In addition, there is degeneration of some Purkinje cells and Golgi neurons. In spite of all these alterations, the regular architecture of the cerebellar folia is retained in many places. In the present study, we used immunocytochemistry with an immune serum raised against glutamic acid decar☐ylase to further characterize the cis -dichlorodiammineplatinum-induced alterations of GABAergic neurons. The aim was to examine cerebellar development and to test for factors controlling the settling of GABAergic circuits. At all post-treatment intervals, most of the Purkinje and Golgi neurons and molecular layer interneurons showed stronger anti-glutamic acid decar☐ylase immunoreactivity than in controls; this may have been due to altered fixation because of cis -dichlorodiammineplatinum-induced damages to the blood vessels; but could also reflect cellular retention of the enzyme, maybe due to cis -dichlorodiammineplatinum-induced damage of the microtubular apparatus. After seven days, large roundish immunoreactive varicosities were present in the molecular layer adjacent to the Purkinje cell dendritic poles. These varicosities, which were not observed in control animals, may be terminals of Purkinje cell axon recurrent collaterals contributing to the supraganglionic plexus, whose abnormal development would compensate for the reduced inhibitory inputs from inhibitory interneurons and/or Purkinje cells, which degenerated at early post-treatment intervals. At later post-treatment intervals (15 and 21 days), there were also alterations in the pericellular basket at the Purkinje cell axon hillock, which was poorly developed in or absent from the majority of cells. The finding was confirmed by morphological observation of basket cells in Golgi-Cox preparation and immunocytochemistry with an antibody raised against 200,000 mol. wt phosphorylated neurofilaments. It is concluded that early changes in anti-glutamic acid decar☐ylase immunoreactivity of neurons may be due to a direct interference of the drug with the cellular metabolic pathways. The late anomalies in the anti-glutamic acid decar☐ylase immunoreactivity appear to be secondary to changes in the tissue cytoarchitecture rather than being primary cis -dichlorodiammineplatinum-induced lesions of the cells.