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Backgrounds: There is a few available information about Coronavirus disease- 2019 (Covid-19) behavior in Latin American countries. We aimed to evaluate the association between laboratory tests and complications risk factors in SARS-CoV-2 infection in a Mexican population. Methods: We analyzed retrospective routinely collected data for Covid-19 patients in Hospital Regional de Alta Especialidad de Ixtapaluca, Mexico. We identify adult patients (aged ≥18 years) with a positive test for SARS-CoV-2 and oxygen support, between March 28 and May 5, 2020. We described the demographic and clinical laboratory differences and assessed the association with complications between the outcome and potential prognosis factor using two-sided Fisher's exact test and unadjusted odds ratio calculation. Findings Between March 28, 2020, and May 5, 2020, we traced 195 adult patients (aged ≥18 years) with a positive test for SARS-CoV-2 and oxygen support. We estimated the cases of chronic diseases, 28·4% patients had diabetes and 24·4% hypertension. Only 12·7% of the patients suffer both conditions. There was no statistical association between death, and diabetes and hypertension coexistence; (p= 0·82). Besides, we observed that patients with a BMI between 35-39·9 kg/m2 (9·2%) had a 63·6% mortality rate. Compared to the survivors´ patients, the full blood count test showed a higher median of leucocytes count in non- survivors of 11·4 per 103 mcL; (p= 800ng/ml (uOR 3·97 [95% CI 1·51 - 10·43]) and male sex (uOR 2·79 [95% CI 1·36 - 5·74]). The Kaplan- Meier estimator indicated that the mean survival time was 17·84 days. Interpretation: Mexican population reported similar demographic and clinical characteristics as observed in other countries. Contrary as we expect, diabetes was not associated with higher risk of complications in Covid-19 patients. Trial Registration: This study is part of a protocol, which is registered in ClinicalTrials.gov, NCT04434157. Funding Statement: None. Declaration of Interests: All authors declare no competing interest. Ethics Approval Statement: This study was approved by the institutional Research and Ethics Committee at HRAEI (protocol NR-09-2020). The required informed consent was waived because of the study design.