26 results on '"Chandrasekhar, Srinivasan"'
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2. Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1
3. Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors
4. Identification and biological activity of 6-alkyl-substituted 3-methyl-pyridine-2-carbonyl amino dimethyl-benzoic acid EP4 antagonists
5. Discovery of potent aryl-substituted 3-[(3-methylpyridine-2-carbonyl) amino]-2,4-dimethyl-benzoic acid EP4 antagonists with improved pharmacokinetic profile
6. Discovery of substituted-2,4-dimethyl-(naphthalene-4-carbonyl)amino-benzoic acid as potent and selective EP4 antagonists
7. Discovery and characterization of a potent and selective EP4 receptor antagonist
8. Differential regulation of cytokine-induced MMP-1 and MMP-13 expression by p38 kinase inhibitors in human chondrosarcoma cells: potential role of Runx2 in mediating p38 effects
9. Regulation of the human ADAMTS-4 promoter by transcription factors and cytokines
10. Distinct pathways of extracellular signal-regulated kinase activation by growth factors, fibronectin and parathyroid hormone 1–34
11. Protein Kinase C Is a Mediator of the Synthesis and Secretion of Osteoprotegerin in Osteoblast-like Cells
12. Crystal Structure of Human Parathyroid Hormone 1–34 at 0.9-Å Resolution
13. Activation of Osteocalcin Transcription Involves Interaction of Protein Kinase A- and Protein Kinase C-dependent Pathways
14. Parathyroid Hormone-(1–34) Enhances Aggrecan Synthesis via an Insulin-like Growth Factor-I Pathway
15. Development of a Scintillation Proximity Assay for High-Throughput Measurement of Intact Parathyroid Hormone
16. The anti-rheumatic potential of a series of 2,4-di-substituted-4H-naphtho[1,2-b]pyran-3-carbonitriles
17. Osteonectin/SPARC is a product of articular chondrocytes/cartilage and is regulated by cytokines and growth factors
18. Intra-Articular Administration of Interleukin-1 Causes Prolonged Suppression of Cartilage Proteoglycan Synthesis in Rats
19. Interleukin-1 -induced suppression of type II collagen gene transcription involves DNA regulatory elements
20. Arthritis induced by interleukin-1 is dependent on the site and frequency of intraarticular injection
21. Microdetermination of proteoglycans and glycosaminoglycans in the presence of guanidine hydrochloride
22. Interleukin-1-induced alterations in proteoglycan metabolism and matrix assembly
23. Regulation of Type I Collagen Fibril Assembly by Link Protein and Proteoglycans
24. Transforming growth factor-β is a potent inhibitor of IL-1 induced protease activity and cartilage proteoglycan degradation
25. Direct visualization of collagens and procollagens in polyacrylamide gels
26. Synthesis of type IX collagen: Effect of β-xylosides
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