1. Data on the anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin in mice
- Author
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Ki Jong Rhee, Eun Ha Lee, Kyungsu Kang, Cheol-Ho Pan, and Chang Gun Lee
- Subjects
0301 basic medicine ,Multidisciplinary ,biology ,Selaginella tamariscina ,Amentoflavone ,Pharmacology ,lcsh:Computer applications to medicine. Medical informatics ,Selaginella tamariscina extract ,biology.organism_classification ,In vitro ,03 medical and health sciences ,chemistry.chemical_compound ,030104 developmental biology ,Nude mouse ,chemistry ,In vivo ,medicine ,lcsh:R858-859.7 ,Doxorubicin Hydrochloride ,Doxorubicin ,lcsh:Science (General) ,lcsh:Q1-390 ,medicine.drug - Abstract
Here, we report animal experimental data associated with the article entitled “AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo“ (Jung et al., 2017) [1]. We tested the synergistic anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin hydrochloride in a nude mouse xenograft model of A549 human lung cancer cells. In our experiment, Selaginella tamariscina extract and amentoflavone were administered orally; and doxorubicin hydrochloride was injected intraperitoneally. We expect our preliminary data will be helpful to the development of the anticancer agent using Selaginella tamariscina extract or amentoflavone. Keywords: Amentoflavone, Anti-tumor, Doxorubicin, Selaginella tamariscina
- Published
- 2017
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