56 results on '"Chen, Chiung-Tong"'
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2. Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation
3. Peritoneal effluent MicroRNA profile for detection of encapsulating peritoneal sclerosis
4. Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone
5. Implanted islet mass influences the effects of dipeptidyl peptidase-IV inhibitor LAF237 on transplantation outcomes in diabetic mice
6. DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity
7. Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease
8. BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy
9. Peritoneal Effluent Microrna Profile in Encapsulating Peritoneal Sclerosis
10. Molecular profiling of afatinib-resistant non-small cell lung cancer cells in vivo derived from mice
11. A bubble bursting-mediated oral drug delivery system that enables concurrent delivery of lipophilic and hydrophilic chemotherapeutics for treating pancreatic tumors in rats
12. Repurposing old drugs as antiviral agents for coronaviruses
13. Artificial intelligence approach fighting COVID-19 with repurposing drugs
14. A novel flavivirus entry inhibitor, BP34610, discovered through high-throughput screening with dengue reporter viruses
15. Effects of boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1
16. The in vivo antinociceptive and μ-opioid receptor activating effects of the combination of N-phenyl-2′,4′-dimethyl-4,5′-bi-1,3-thiazol-2-amines and naloxone
17. A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virus
18. Synthesis and biological evaluation of N-glucosyl indole derivatives as sodium-dependent glucose co-transporter 2 inhibitors
19. Strategies for improving diabetic therapy via alternative administration routes that involve stimuli-responsive insulin-delivering systems
20. Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2
21. Enhanced B-Raf-mediated NRF2 gene transcription and HATs-mediated NRF2 protein acetylation contributes to ABCC1-mediated chemoresistance and glutathione-mediated survival in acquired topoisomerase II poison-resistant cancer cells
22. Multifunctional nanoparticles for oral protein drug delivery
23. N-Indolylglycosides bearing modifications at the glucose C6-position as sodium-dependent glucose co-transporter 2 inhibitors
24. Multifunctional nanoparticles for oral protein drug delivery
25. Self-assembling bubble carriers for oral protein delivery
26. Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations
27. Treatment of chemotherapy-induced neutropenia in a rat model by using multiple daily doses of oral administration of G-CSF-containing nanoparticles
28. Noninvasive imaging oral absorption of insulin delivered by nanoparticles and its stimulated glucose utilization in controlling postprandial hyperglycemia during OGTT in diabetic rats
29. Combination therapy via oral co-administration of insulin- and exendin-4-loaded nanoparticles to treat type 2 diabetic rats undergoing OGTT
30. Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
31. Effects of pH on molecular mechanisms of chitosan–integrin interactions and resulting tight-junction disruptions
32. Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors
33. Elucidating the signaling mechanism of an epithelial tight-junction opening induced by chitosan
34. 3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
35. Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins
36. Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
37. Immune response and pathophysiological features of Klebsiella pneumoniae liver abscesses in an animal model
38. (2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV
39. Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes
40. In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery
41. Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors
42. Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors
43. Non-lethal Candida albicans cph1/cph1 efg1/efg1 mutant partially protects mice from systemic infections by lethal wild-type cells
44. Anti-angiogenic action of 5,5-diphenyl-2-thiohydantoin-N10 (DPTH-N10)
45. Enhanced oral bioavailability of paclitaxel by d-α-tocopheryl polyethylene glycol 400 succinate in mice
46. Shengmai San reduces hepatic lipids and lipid peroxidation in rats fed on a high-cholesterol diet
47. 3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes
48. Development and validation of a liquid chromatography–tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study
49. The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes
50. Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors
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