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Your search keyword '"Chloé Couzin"' showing total 2 results
Start Over Author "Chloé Couzin" Publisher elsevier bv
2 results on '"Chloé Couzin"'

1. Severe hematopoietic stem cell inflammation compromises chronic granulomatous disease gene therapy

Author

Steicy Sobrino, Alessandra Magnani, Michaela Semeraro, Loredana Martignetti, Akira Cortal, Adeline Denis, Chloé Couzin, Capucine Picard, Jacinta Bustamante, Elisa Magrin, Laure Joseph, Cécile Roudaut, Aurélie Gabrion, Tayebeh Soheili, Corinne Cordier, Olivier Lortholary, François Lefrere, Frédéric Rieux-Laucat, Jean-Laurent Casanova, Sylvain Bodard, Nathalie Boddaert, Adrian J. Thrasher, Fabien Touzot, Sophie Taque, Felipe Suarez, Ambroise Marcais, Agathe Guilloux, Chantal Lagresle-Peyrou, Anne Galy, Antonio Rausell, Stephane Blanche, Marina Cavazzana, and Emmanuelle Six

Subjects
General Biochemistry, Genetics and Molecular Biology
Published
2023
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2. 231. Mixed Chimerism After Allogeneic Hematopoietic Stem Cell Transplantation in Sickle Cell Disease: Preliminary Results on Peripheral Blood Sorted Subpopulations and Erythroid Progenitors

Author

Jean Paul Vernant, Françoise Bernaudin, Laure Caccavelli, Annie Kamdem, Chloé Couzin, Dominique Bories, Cécile Arnaud, Fabien Touzot, Eliane Gluckman, Corinne Pondarré, Alessandra Magnani, Marina Cavazzana, Elisa Magrin, Mathieu Fusaro, Jeremy Magalon, Jean Antoine Ribeil, and Emmanuelle Six

Subjects
Pharmacology, Myeloid, Mixed chimerism, business.industry, Erythroid progenitor, medicine.medical_treatment, Myeloablative conditioning, Cell, Hematopoietic stem cell transplantation, Disease, Peripheral blood, medicine.anatomical_structure, Drug Discovery, Immunology, Genetics, medicine, Molecular Medicine, business, Molecular Biology
Abstract

Introduction: Patients with sickle cell disease (SCD) may develop a persistent mixed chimerism (MC) after hematopoietic stem cell transplantation (HSCT) associated with clinical control of the disease. In order to further investigate this condition we analyzed the chimerism in sorted myeloid and lymphoid subpopulations, and erythroid progenitors.Methods: Between 1990 and 2013, 112 sickle cell disease (SCD) patients underwent allogeneic HSCT after myeloablative conditioning. Among the 107 patients with available chimerism at 2 years, 55.1% had a MC, i.e. 9590nana6AA9111.893.83.13.10191223311337.5577AS15513.556.5412.60583471na4975604AS13210.65433.3nana5344444658323717AS1311.547.841.23.21.48575na9273837618A/Dpubjab8012.647.90nana887795959494.59912A/b0Thal579.69503291689698999910011AA5413.49703088781001009998985AA3410.978.38nana444641na5058432AS468.42468.1nana21709.45.43112.5na8AS1339.734.7632.401631121013089AS1539.552.145.920183026161117153AA3310.189.553.22.330631718231317

Published
2016
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