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Adsorption is a promising technology to develop cost-effective carbon capture solutions for the energy and industrial sectors. The PrISMa project aims to develop a technology platform to allow translating specific carbon abatement requirements for CO2 source-sink combinations into key performance indicators (KPIs) that will further translate into property targets for the design of novel materials. This is possible by using materials such as metal organic frameworks (MOFs) which can be tailor-made according to the requirements of the separation process. This work presents the progress on the development of one of the main building blocks for the PrISMa technology platform: a computer-based techno-economic screening tool for the screening of novel adsorption materials. The developed screening tool provides the user with a suite of fit-for-purpose models of adsorption processes that allow to co-optimize the material and process domains. The techno-economic screening tool utilizes the effective carbon price (ECP) as the ultimate metric for the identification of the most promising adsorbent materials, either readily existing, or still to be synthesized. This work presents a preliminary screening of novel adsorption materials for cost-effective CO2 capture for two different applications – a waste to energy plant and an offshore gas turbine combined cycle.