16 results on '"Desrayaud, Sandrine"'
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2. Micropreparative isolation and NMR structure elucidation of metabolites of the drug candidate 1-isopropyl-4-(4-isopropylphenyl)-6-(prop-2-yn-1-yloxy) quinazolin-2(1H)-one from rat bile and urine
3. AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: Identification, SAR and pharmacological characterization
4. Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: Structure based design and in vivo reduction of amyloid β-peptides
5. Discovery of novel indolinone-based, potent, selective and brain penetrant inhibitors of LRRK2
6. MPEP, an mGlu5 receptor antagonist, reduces the development of l-DOPA-induced motor complications in de novo parkinsonian monkeys: Biochemical correlates
7. Discovery of 1H-pyrrolo[2,3-c]pyridine-7-carboxamides as novel, allosteric mGluR5 antagonists
8. 6-Amino quinazolinedione sulfonamides as orally active competitive AMPA receptor antagonists
9. Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors
10. Piperidyl amides as novel, potent and orally active mGlu5 receptor antagonists with anxiolytic-like activity
11. Macrocyclic BACE-1 inhibitors acutely reduce Aβ in brain after po application
12. Macrocyclic peptidomimetic β-secretase (BACE-1) inhibitors with activity in vivo
13. The priorities/needs of the pharmaceutical industry in drug delivery to the brain
14. 6-[2-(Adamantylidene)-hydroxybenzoxazole]-O-sulfamate, a steroid sulfatase inhibitor for the treatment of androgen- and estrogen-dependent diseases
15. Effect of the P-glycoprotein inhibitor, SDZ PSC 833, on the blood and brain pharmacokinetics of colchicine
16. Dose-dependent delivery of colchicine to the rat hippocampus by microdialysis
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