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1. 1. Quantitative evaluation of polyacrylamide gel electrophoretic results is essential for comparative macromolecular mapping. 2. 2. Comparison of electrophorograms arising in a continuous signal ∗ is possible when sufficient colinearity of the resolved bands is achieved. 3. 3. Comparison of protein patterns arising in a discontinuous signal must rely upon statistical evaluation of densitometric recordings. 4. 4. Examples of the two different types of comparison are given from the study of rat ontogenesis.