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20 results on '"Finetti, Pascal"'

2. DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer

Author

Le, Thi Khanh, primary, Cherif, Chaïma, additional, Omabe, Kenneth, additional, Paris, Clément, additional, Lannes, François, additional, Audebert, Stéphane, additional, Baudelet, Emilie, additional, Hamimed, Mourad, additional, Barbolosi, Dominique, additional, Finetti, Pascal, additional, Bastide, Cyrille, additional, Fazli, Ladan, additional, Gleave, Martin, additional, Bertucci, François, additional, Taïeb, David, additional, and Rocchi, Palma, additional

Published
2023
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3. Axin1 Protects Colon Carcinogenesis by an Immune-Mediated Effect

Author

Sanson, Romain, primary, Lazzara, Silvia Luna, additional, Cune, David, additional, Pitasi, Caterina Luana, additional, Trentesaux, Coralie, additional, Fraudeau, Marie, additional, Letourneur, Franck, additional, Saintpierre, Benjamin, additional, Le Gall, Morgane, additional, Bossard, Pascale, additional, Terris, Benoit, additional, Finetti, Pascal, additional, Bertucci, François, additional, Mamessier, Emilie, additional, Romagnolo, Béatrice, additional, and Perret, Christine, additional

Published
2023
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7. Mo1343 TRANSCRIPTOMIC ANALYSIS OF LASER CAPTURE MICRODISSECTED PDAC TUMORS REVEALS MOLECULAR SUBTYPES AND A 13-GENE PROGNOSTIC CLASSIFIER

Author

Begg, Sebastian, primary, Birnbaum, David, additional, Finetti, Pascal, additional, Neyaz, Azfar, additional, Mino-Kenudson, Mari, additional, Deshpande, Vikram, additional, Hank, Thomas P., additional, Lillemoe, Keith, additional, Warshaw, Andrew L., additional, Castillo, Carlos Fernandez-del, additional, Ting, David T., additional, and Liss, Andrew S., additional

Published
2020
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8. ProNGF increases breast tumor aggressiveness through functional association of TrkA with EphA2

Author

Lévêque, Romain, primary, Corbet, Cyril, additional, Aubert, Léo, additional, Guilbert, Matthieu, additional, Lagadec, Chann, additional, Adriaenssens, Eric, additional, Duval, Jérémy, additional, Finetti, Pascal, additional, Birnbaum, Daniel, additional, Magné, Nicolas, additional, Chopin, Valérie, additional, Bertucci, François, additional, Le Bourhis, Xuefen, additional, and Toillon, Robert-Alain, additional

Published
2019
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9. The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling

Author

Lopez Almeida, Leonor, primary, Sebbagh, Michael, additional, Bertucci, François, additional, Finetti, Pascal, additional, Wicinski, Julien, additional, Marchetto, Sylvie, additional, Castellano, Rémy, additional, Josselin, Emmanuelle, additional, Charafe-Jauffret, Emmanuelle, additional, Ginestier, Christophe, additional, Borg, Jean-Paul, additional, and Santoni, Marie-Josée, additional

Published
2018
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11. Characterization and Targeting of Platelet-Derived Growth Factor Receptor alpha (PDGFRA) in Inflammatory Breast Cancer (IBC)

Author

Joglekar-Javadekar, Madhura, primary, Van Laere, Steven, additional, Bourne, Michael, additional, Moalwi, Manal, additional, Finetti, Pascal, additional, Vermeulen, Peter B., additional, Birnbaum, Daniel, additional, Dirix, Luc Y., additional, Ueno, Naoto, additional, Carter, Monique, additional, Rains, Justin, additional, Ramachandran, Abhijit, additional, Bertucci, Francois, additional, and van Golen, Kenneth L., additional

Published
2017
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12. miR-600 Acts as a Bimodal Switch that Regulates Breast Cancer Stem Cell Fate through WNT Signaling

Author

El Helou, Rita, primary, Pinna, Guillaume, additional, Cabaud, Olivier, additional, Wicinski, Julien, additional, Bhajun, Ricky, additional, Guyon, Laurent, additional, Rioualen, Claire, additional, Finetti, Pascal, additional, Gros, Abigaelle, additional, Mari, Bernard, additional, Barbry, Pascal, additional, Bertucci, Francois, additional, Bidaut, Ghislain, additional, Harel-Bellan, Annick, additional, Birnbaum, Daniel, additional, Charafe-Jauffret, Emmanuelle, additional, and Ginestier, Christophe, additional

Published
2017
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13. Comparison of Induced Sputum and Bronchoalveolar Lavage in Lung Transplant Recipients

Author

Bertucci, François, Finetti, Pascal, Cervera, Nathalie, Charafe-Jauffret, Emmanuelle, Adélaïde, José, Debono, Stéphane, Houvenaeghel, Gilles, Maraninchi, Dominique, Viens, Patrice, Charpin, Colette, Jacquemier, Jocelyne, Birnbaum, Daniel, Mamessier, Emilie, Magnan, Antoine, Centre de Recherche en Cancérologie de Marseille (CRCM), Aix Marseille Université (AMU)-Institut Paoli-Calmettes, and Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Adult, Graft Rejection, Male, Pulmonary and Respiratory Medicine, Cystic Fibrosis, Heart-Lung Transplantation, Neutrophils, medicine.medical_treatment, Bronchiolitis obliterans, [SDV.CAN]Life Sciences [q-bio]/Cancer, Bronchi, Cell Count, MESH: Th2 Cells, Humans, Medicine, Lung transplantation, Respiratory function, Bronchiolitis Obliterans, Chemokine CCL5, ComputingMilieux_MISCELLANEOUS, Biologic marker, MESH: Cytokines, Transplantation, MESH: Humans, medicine.diagnostic_test, business.industry, Interleukin-8, Sputum, [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy, Middle Aged, respiratory system, medicine.disease, humanities, Neutrophilia, Respiratory Function Tests, respiratory tract diseases, Bronchoalveolar lavage, Immunology, Female, Surgery, MESH: Hypersensitivity, Immediate, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Bronchoalveolar Lavage Fluid, Immunosuppressive Agents, Lung Transplantation
Abstract

Background Chronic lung rejection is characterized by obliterative bronchiolitis (OB) diagnosed based on spirometric criteria reflecting an already advanced process. Biologic markers such as bronchoalveolar lavage (BAL) neutrophilia or increased levels of chemokines (interleukin-8, RANTES [regulated on activation: normal T cell expressed and secreted]) have been proposed as early diagnosis tools. However, BAL is too invasive to be used as a routine strategy. Induced sputum (IS), however, is a non-invasive method of recovering bronchial cells. Methods The aim of this study was to compare BAL and IS differential cellular counts as well as IL-8 and RANTES levels between patients with bronchiolitis obliterans syndrome (BOS), recipients with good outcome and well-preserved lung function (non-BOS) and non-transplanted controls. We compared 34 BAL and IS findings obtained consecutively from 34 lung transplant recipients (LTRs), including 22 non-BOS and 12 BOS patients. Results IS results were compared with 19 samples from non-transplanted controls. IS was well tolerated. There was no correlation between BAL and sputum cell populations. BAL neutrophils and IL-8 levels were increased in BOS, and these parameters were positively correlated. Moreover, BAL neutrophils and IL-8 levels were both negatively correlated with respiratory function. Sputum evaluation allows discrimination of BOS from non-BOS by the presence of higher neutrophil and eosinophil counts. Moreover, IS neutrophils and eosinophils were both correlated with lung function parameters. In contrast to BAL, IL-8 level in sputum was not a useful predictive marker of BOS development. IS RANTES levels were higher in BOS than in healthy recipients and correlated significantly with IS eosinophils. Conclusions IS and BAL provide different but complementary data. In this study, IS appeared to be a useful, non-invasive tool for LTR monitoring. Furthermore, IS provides new insights into BOS pathogenesis, especially with regard to implication of eosinophils and its chemokine, RANTES, at the bronchial level.

Published
2006

16. The Functional Landscape of Hsp27 Reveals New Cellular Processes such as DNA Repair and Alternative Splicing and Proposes Novel Anticancer Targets

Author

Katsogiannou, Maria, primary, Andrieu, Claudia, additional, Baylot, Virginie, additional, Baudot, Anaïs, additional, Dusetti, Nelson J., additional, Gayet, Odile, additional, Finetti, Pascal, additional, Garrido, Carmen, additional, Birnbaum, Daniel, additional, Bertucci, François, additional, Brun, Christine, additional, and Rocchi, Palma, additional

Published
2014
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