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66 results on '"Franck, Nicolas"'

1. Functioning, clinical severity, education and sex moderate the inverse relationship between insight and quality of life in patients with schizophrenia

Author

Barbalat, Guillaume, primary, Maréchal, Lisa, additional, Plasse, Julien, additional, Chéreau-Boudet, Isabelle, additional, Gouache, Benjamin, additional, Legros-Lafarge, Emilie, additional, Massoubre, Catherine, additional, Guillard-Bouhet, Nathalie, additional, Haesebaert, Frédéric, additional, and Franck, Nicolas, additional

Published
2024
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4. CLINICAL UTILITY OF SYSTEMATIC CGH-ARRAY GENETIC TESTING IN REAL WORLD SCHIZOPHRENIA

Author

Rey, Romain, primary, Poisson, Alice, additional, Lio, Guillaume, additional, Franck, Nicolas, additional, Chatron, Nicolas, additional, Till, Marianne, additional, Bralet, Marie-Cécile, additional, Babinet, Marie-Noëlle, additional, Bardel-Danjean, Claire, additional, Sanlaville, Damien, additional, Lesca, Gaëtan, additional, and Demily, Caroline, additional

Published
2022
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8. Functioning and cognitive characteristics of clozapine users referred to psychosocial rehabilitation centers: A REHABase cohort study

Author

VERDOUX, Hélène, primary, QUILES, Clélia, additional, CERVELLO, Sophie, additional, DUBREUCQ, Julien, additional, BON, Laura, additional, MASSOUBRE, Catherine, additional, POMMIER, Romain, additional, LEGROS-LAFARGE, Emilie, additional, JAAFARI, Nemat, additional, GUILLARD-BOUHET, Nathalie, additional, CHÉREAU-BOUDET, Isabelle, additional, COUHET, Geoffroy, additional, PLASSE, Julien, additional, and FRANCK, Nicolas, additional

Published
2019
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10. Tacrolimus exposure after liver transplantation for alcohol-related liver disease: Impact on complications

Author

Olivier Guillaud, Olivier Boillot, Franck-Nicolas Bardou, Christine Chambon-Augoyard, Domitille Erard-Poinsot, Mélanie Vallin, Jérôme Dumortier, Elsa Thimonier, Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon

Subjects
Male, Risk, medicine.medical_specialty, Skin Neoplasms, Time Factors, Drug-Related Side Effects and Adverse Reactions, [SDV]Life Sciences [q-bio], medicine.medical_treatment, Immunology, 030230 surgery, Liver transplantation, Gastroenterology, Tacrolimus, 03 medical and health sciences, Liver disease, Postoperative Complications, 0302 clinical medicine, Internal medicine, Diabetes mellitus, Humans, Immunology and Allergy, Medicine, Adverse effect, Liver Diseases, Alcoholic, Transplantation, business.industry, Middle Aged, medicine.disease, Liver Transplantation, 3. Good health, stomatognathic diseases, Immunosuppressive drug, Cytomegalovirus Infections, Hypertension, Female, France, business, Immunosuppressive Agents, Dyslipidemia, Follow-Up Studies, 030215 immunology
Abstract

Alcohol-related liver disease (ALD) is one of the main indications for liver transplantation (LT). For 20 years, tacrolimus (Tac) is the cornerstone immunosuppressive drug used after LT and is very efficient for the prevention of rejection. Nevertheless, the major drawback of long-term use of Tac is the risk for developing dose-dependent adverse effects.The aim of the present study was to assess the impact of Tac exposure (trough concentrations and concentration/dose (C/D) ratio) during the first year after LT, on short- and long-term complications after LT for ALD.All patients who underwent a LT for ALD at Lyon Edouard Herriot Hospital from October 1990 to September 2010, and who were treated with Tac for at least one year after LT, were analyzed.The study population consisted in 251 patients, mean age 53.4 ± 7.3 years, and followed during 11.6 ± 4.8 years. Post-LT complications included severe infectious events (44.6%), malignancies (41.4%), arterial hypertension (49.4%) dyslipidemia (44.2%), diabetes (18.7%) and cardiovascular events (15.5%). De novo hypertension, cardiovascular event, CMV infection, non-melanoma skin cancers and HCC recurrence after transplantation were significantly associated with higher Tac trough blood concentration. In addition, Tac fast-metabolizers (defined as C/D 1.8) had significantly more impaired renal function at 1, 5, and 10 years and more cardiovascular events, PTLD, diabetes and hypertension than slow-metabolizers.Our results strongly support that, in addition to blood trough concentrations, Tac metabolism, as estimated by the simple C/D ratio, could be an efficient parameter in daily practice to identify LT patients at risk to develop long term general complications of Tac.

Published
2019

11. From “under” to “over” social cognition in schizophrenia: Is there distinct profiles of impairments according to negative and positive symptoms?

Author

Peyroux, Elodie, primary, Prost, Zelda, additional, Danset-Alexandre, Charlotte, additional, Brenugat-Herne, Lindsay, additional, Carteau-Martin, Isabelle, additional, Gaudelus, Baptiste, additional, Jantac, Célia, additional, Attali, David, additional, Amado, Isabelle, additional, Graux, Jérôme, additional, Houy-Durand, Emmanuelle, additional, Plasse, Julien, additional, and Franck, Nicolas, additional

Published
2019
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25. Specific vs general cognitive remediation for executive functioning in schizophrenia: A multicenter randomized trial

Author

Franck, Nicolas, primary, Duboc, Chloé, additional, Sundby, Charlotte, additional, Amado, Isabelle, additional, Wykes, Til, additional, Demily, Caroline, additional, Launay, Corinne, additional, Le Roy, Vincent, additional, Bloch, Pascal, additional, Willard, Dominique, additional, Todd, Aurélia, additional, Petitjean, François, additional, Foullu, Sandrine, additional, Briant, Patrick, additional, Grillon, Marie-Laure, additional, Deppen, Patricia, additional, Verdoux, Hélène, additional, Bralet, Marie-Cécile, additional, Januel, Dominique, additional, Riche, Benjamin, additional, Roy, Pascal, additional, and Vianin, Pascal, additional

Published
2013
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34. Il faut raison garder

Author

Willard, Marc, primary, Franck, Nicolas, additional, Gut-Fayand, Anne, additional, Hodé, Yann, additional, Murad, Ayman., additional, Simonet, Marc, additional, and Willard, Dominique, additional

Published
2011
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45. Mental rotation in schizophrenia

Author

de Vignemont, Frédérique, primary, Zalla, Tiziana, additional, Posada, Andrés, additional, Louvegnez, Anne, additional, Koenig, Olivier, additional, Georgieff, Nicolas, additional, and Franck, Nicolas, additional

Published
2006
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