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Your search keyword '"García-Mendiola, Tania"' showing total 13 results
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13 results on '"García-Mendiola, Tania"'

2. Free PCR virus detection via few-layer bismuthene and tetrahedral DNA nanostructured assemblies

Author

Gutiérrez-Gálvez, Laura, primary, García-Fernández, Daniel, additional, Barrio, Melisa del, additional, Luna, Mónica, additional, Torres, Íñigo, additional, Zamora, Félix, additional, Navío, Cristina, additional, Milán-Rois, Paula, additional, Castellanos, Milagros, additional, Abreu, Melanie, additional, Cantón, Rafael, additional, Galán, Juan Carlos, additional, Somoza, Álvaro, additional, Miranda, Rodolfo, additional, García-Mendiola, Tania, additional, and Lorenzo, Encarnación, additional

Published
2024
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3. Methylene Blue functionalized carbon nanodots combined with different shape gold nanostructures for sensitive and selective SARS-CoV-2 sensing

Author

Pina-Coronado, Clara, primary, Martínez-Sobrino, Álvaro, additional, Gutiérrez-Gálvez, Laura, additional, Del Caño, Rafael, additional, Martínez-Periñán, Emiliano, additional, García-Nieto, Daniel, additional, Rodríguez-Peña, Micaela, additional, Luna, M., additional, Milán-Rois, Paula, additional, Castellanos, Milagros, additional, Abreu, Melanie, additional, Cantón, Rafael, additional, Galán, Juan Carlos, additional, Pineda, Teresa, additional, Pariente, Félix, additional, Somoza, Álvaro, additional, García-Mendiola, Tania, additional, Miranda, Rodolfo, additional, and Lorenzo, Encarnación, additional

Published
2022
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4. Paving the way to point of care (POC) devices for SARS-CoV-2 detection

Author

Kaci, Karim, primary, del Caño, Rafael, additional, Luna, Mónica, additional, Milán-Rois, Paula, additional, Castellanos, Milagros, additional, Abreu, Melanie, additional, Cantón, Rafael, additional, Galán, Juan Carlos, additional, Somoza, Álvaro, additional, Miranda, Rodolfo, additional, González de Rivera, Guillermo, additional, García-Mendiola, Tania, additional, and Lorenzo, Encarnación, additional

Published
2022
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5. Paving the way to Point of Care (POC) devices for SARS-CoV-2 detection [Dataset]

Author

Kaci, Karim, Caño, Rafael del, Luna, Mónica, Milán-Rois, Paula, Castellanos, Milagros, Abreu, Melanie, Cantón, Rafael, Galán, Juan Carlos, Somoza, Álvaro, Miranda, Rodolfo, González de Rivera, Guillermo, García-Mendiola, Tania, Lorenzo, Encarnación, Kaci, Karim, Caño, Rafael del, Luna, Mónica, Milán-Rois, Paula, Castellanos, Milagros, Abreu, Melanie, Cantón, Rafael, Galán, Juan Carlos, Somoza, Álvaro, Miranda, Rodolfo, González de Rivera, Guillermo, García-Mendiola, Tania, and Lorenzo, Encarnación

Published
2022

6. Paving the way to point of care (POC) devices for SARS-CoV-2 detection

Author

Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Ministerio de Economía y Competitividad (España), Comunidad de Madrid, European Commission, Fundación Instituto Madrileño de Estudios Avanzados en Nanociencia, Universidad Autónoma de Madrid, Banco Santander, Conferencia de Rectores de las Universidades Españolas, Consejo Superior de Investigaciones Científicas (España), Kaci, Karim, Caño, Rafael del, Luna, Mónica, Milán-Rois, Paula, Castellanos, Milagros, Abreu, Melanie, Cantón, Rafael, Galán, Juan Carlos, Somoza, Álvaro, Miranda, Rodolfo, González de Rivera, Guillermo, García-Mendiola, Tania, Lorenzo, Encarnación, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Ministerio de Economía y Competitividad (España), Comunidad de Madrid, European Commission, Fundación Instituto Madrileño de Estudios Avanzados en Nanociencia, Universidad Autónoma de Madrid, Banco Santander, Conferencia de Rectores de las Universidades Españolas, Consejo Superior de Investigaciones Científicas (España), Kaci, Karim, Caño, Rafael del, Luna, Mónica, Milán-Rois, Paula, Castellanos, Milagros, Abreu, Melanie, Cantón, Rafael, Galán, Juan Carlos, Somoza, Álvaro, Miranda, Rodolfo, González de Rivera, Guillermo, García-Mendiola, Tania, and Lorenzo, Encarnación

Abstract

In this work we present a powerful, affordable, and portable biosensor to develop Point of care (POC) SARS-CoV-2 virus detection. It is constructed from a fast, low cost, portable and electronically automatized potentiostat that controls the potential applied to a disposable screen-printed electrochemical platform and the current response. The potentiostat was designed to get the best signal-to-noise ratio, a very simple user interface offering the possibility to be used by any device (computer, mobile phone or tablet), to have a small and portable size, and a cheap manufacturing cost. Furthermore, the device includes as main components, a data acquisition board, a controller board and a hybridization chamber with a final size of 10 × 8 × 4 cm. The device has been tested by detecting specific SARS-CoV-2 virus sequences, reaching a detection limit of 22.1 fM. Results agree well with those obtained using a conventional potentiostat, which validate the device and pave the way to the development of POC biosensors. In this sense, the device has finally applied to directly detect the presence of the virus in nasopharyngeal samples of COVID-19 patients and results confirm its utility for the rapid detection infected samples avoiding any amplification process.

Published
2022

7. Methylene Blue functionalized carbon nanodots combined with different shape gold nanostructures for sensitive and selective SARS-CoV-2 sensing

Author

Comunidad de Madrid, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Conferencia de Rectores de las Universidades Españolas, Banco Santander, Consejo Superior de Investigaciones Científicas (España), Pina-Coronado, Clara, Martínez-Sobrino, Álvaro, Gutiérrez-Gálvez, Laura, Caño, Rafael del, Martínez-Periñán, Emiliano, García-Nieto, Daniel, Rodríguez-Peña, Micaela, Luna, Mónica, Milán-Rois, Paula, Castellanos, Milagros, Abreu, Melanie, Cantón, Rafael, Galán, Juan Carlos, Pineda, Teresa, Pariente, Félix, Somoza, Álvaro, García-Mendiola, Tania, Miranda, Rodolfo, Lorenzo, Encarnación, Comunidad de Madrid, Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Conferencia de Rectores de las Universidades Españolas, Banco Santander, Consejo Superior de Investigaciones Científicas (España), Pina-Coronado, Clara, Martínez-Sobrino, Álvaro, Gutiérrez-Gálvez, Laura, Caño, Rafael del, Martínez-Periñán, Emiliano, García-Nieto, Daniel, Rodríguez-Peña, Micaela, Luna, Mónica, Milán-Rois, Paula, Castellanos, Milagros, Abreu, Melanie, Cantón, Rafael, Galán, Juan Carlos, Pineda, Teresa, Pariente, Félix, Somoza, Álvaro, García-Mendiola, Tania, Miranda, Rodolfo, and Lorenzo, Encarnación

Abstract

The development of DNA-sensing platforms based on new synthetized Methylene Blue functionalized carbon nanodots combined with different shape gold nanostructures (AuNs), as a new pathway to develop a selective and sensitive methodology for SARS-CoV-2 detection is presented. A mixture of gold nanoparticles and gold nanotriangles have been synthetized to modify disposable electrodes that act as an enhanced nanostructured electrochemical surface for DNA probe immobilization. On the other hand, modified carbon nanodots prepared a la carte to contain Methylene Blue (MB-CDs) are used as electrochemical indicators of the hybridization event. These MB-CDs, due to their structure, are able to interact differently with double and single-stranded DNA molecules. Based on this strategy, target sequences of the SARS-CoV-2 virus have been detected in a straightforward way and rapidly with a detection limit of 2.00 aM. Moreover, this platform allows the detection of the SARS-CoV-2 sequence in the presence of other viruses, and also a single nucleotide polymorphism (SNPs). The developed approach has been tested directly on RNA obtained from nasopharyngeal samples from COVID-19 patients, avoiding any amplification process. The results agree well with those obtained by RT-qPCR or reverse transcription quantitative polymerase chain reaction technique.

Published
2022

9. A MoS2 platform and thionine-carbon nanodots for sensitive and selective detection of pathogens

Author

Martínez-Periñán, Emiliano, primary, García-Mendiola, Tania, additional, Enebral-Romero, Estefanía, additional, del Caño, Rafael, additional, Vera-Hidalgo, Mariano, additional, Vázquez Sulleiro, Manuel, additional, Navío, Cristina, additional, Pariente, Félix, additional, Pérez, Emilio M., additional, and Lorenzo, Encarnación, additional

Published
2021
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