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Start Over Author "Ge, Shaoyang" Publisher elsevier bv
3 results on '"Ge, Shaoyang"'

2. Complete genome sequence of Lactobacillus salivarius Ren, a probiotic strain with anti-tumor activity

Author

Ge Shaoyang, Huiyuan Guo, Liang Zhao, Lu Jiang, Erna Sun, Fazheng Ren, Ming Zhang, Hao Zhang, and Liu Songling

Subjects
China, Molecular Sequence Data, Antineoplastic Agents, Bioengineering, Biology, medicine.disease_cause, Applied Microbiology and Biotechnology, Genome, Microbiology, law.invention, Feces, Probiotic, Plasmid, Bacterial Proteins, Genome Size, law, medicine, Humans, Aged, 80 and over, Whole genome sequencing, Base Composition, Strain (chemistry), Probiotics, Lactobacillus salivarius, Sequence Analysis, DNA, General Medicine, biology.organism_classification, Lactobacillus, Carcinogenesis, Genome, Bacterial, Genotoxicity, Biotechnology
Abstract

Lactobacillus salivarius Ren (LsR) (CGMCC No. 3606) is a probiotic strain that was isolated from the feces of a healthy centenarian living in Bama, Guangxi, China. Previous studies have shown that this strain decreases 4-nitroquinoline 1-oxide (4-NQO)-induced genotoxicity in vitro. It also suppresses 4-NQO-induced oral carcinogenesis and 1,2-dimethylhydrazine (DMH)-induced colorectal carcinogenesis, and therefore may be used as an adjuvant therapeutic agent for cancer. Here, we report the complete genome sequence of LsR that consists of a circular chromosome of 1751,565 bp and two plasmids (pR1, 176,951 bp; pR2, 49,848 bp).

Published
2015
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