Search

Your search keyword '"Giménez Arnau, A."' showing total 254 results
Start Over Author "Giménez Arnau, A." Publisher elsevier bv
254 results on '"Giménez Arnau, A."'

1. Actualización de la batería estándar y batería ampliada de pruebas alérgicas de contacto por el Grupo Español de Investigación en Dermatitis de Contacto y Alergia Cutánea (GEIDAC)

Author

Navarro-Triviño, Francisco José, primary, Borrego, Leopoldo, additional, Silvestre-Salvador, Juan Francisco, additional, Mercader-García, Pedro, additional, Giménez-Arnau, Ana M, additional, de Frutos, Francisco Javier Ortiz, additional, Sanz-Sánchez, Tatiana, additional, Melé-Ninot, Gemma, additional, Sánchez-Gilo, Araceli, additional, Zaragoza-Ninet, Violeta, additional, Serra-Baldrich, Esther, additional, Miquel-Miquel, Javier, additional, Córdoba-Guijarro, Susana, additional, Rodríguez-Serna, Mercedes, additional, Ruíz-González, Inmaculada, additional, Manuel Carrascosa-Carrillo, José, additional, de la Fuente, Enrique Gómez, additional, Pastor-Nieto, María Antonia, additional, Heras-Mendaza, Felipe, additional, González-Pérez, Ricardo, additional, Guillén, Paloma Sánchez-Pedreño, additional, Sánchez-Pérez, Javier, additional, Gatica-Ortega, María Elena, additional, Fernández-Redondo, Virginia, additional, Hervella-Garcés, Marcos, additional, Manrique-Martínez, Pilar, additional, Guimaraens-Juanena, Dolores, additional, García-Gavín, Juan, additional, Giménez-Arnau, Elena, additional, Figueras-Nart, Ignaci, additional, Curto-Barredo, Laia, additional, and Carlos Armario-Hita, José, additional

Published
2024
Full Text
View/download PDF

2. Usage prevalence of angioedema patient-reported outcome measures: results from the UCARE and ACARE PROMUSE study

Author

Cherrez-Ojeda, Ivan, primary, Bousquet, Jean, additional, Giménez-Arnau, Ana, additional, Godse, Kiran, additional, Krasowska, Dorota, additional, Bartosińska, Joanna, additional, Szczepanik-Kułak, Paulina, additional, Wawrzycki, Bartłomiej, additional, Kolkhir, Pavel, additional, Allenova, Anastasiia, additional, Allenov, Andrey, additional, Tkachenko, Sergey, additional, Teovska Mitrevska, Natasa, additional, Mijakoski, Dragan, additional, Stoleski, Sasho, additional, Kolacinska-Flont, Marta, additional, Kuprys-Lipinska, Izabela, additional, Molinska, Joanna, additional, Kasperska-Zając, Alicja, additional, Zajac, Magdalena, additional, Zamlynski, Mateusz, additional, Mihaltan, Florin, additional, Ulmeanu, Ruxandra, additional, Zalewska-Janowska, Anna, additional, Tomaszewska, Katarzyna, additional, Al-Ahmad, Mona, additional, Al-Nesf, Maryam Ali, additional, Ibrahim, Tayseer, additional, Aqel, Sami, additional, Pesqué, David, additional, Rodríguez-González, Mónica, additional, Wakida-Kuzunoki, Guillermo Hideo, additional, Ramon, German D., additional, Ramon, Gonzalo N., additional, Neisinger, Sophia, additional, Bonnekoh, Hanna, additional, Rukhadze, Maia, additional, Khoshkhui, Maryam, additional, Fomina, Daria, additional, Larenas-Linnemann, Désirée, additional, Košnik, Mitja, additional, Oztas Kara, Rabia, additional, Caballero López, Chrystopherson Gengyny, additional, Liu, Qiang, additional, Ivancevich, Juan Carlos, additional, Ensina, Luis Felipe, additional, Rosario, Nelson, additional, Kvedariene, Violeta, additional, Ben-Shoshan, Moshe, additional, Criado, Roberta Fachini Jardim, additional, Bauer, Andrea, additional, Cherrez, Annia, additional, Cherrez, Sofia, additional, Chong-Neto, Herberto, additional, Rojo-Gutierrez, Maria Isabel, additional, Rudenko, Michael, additional, Larco Sousa, José Ignacio, additional, Lesiak, Aleksandra, additional, Matos, Edgar, additional, Tinoco, Ivan, additional, Crespo Shijin, Carolina, additional, Hinostroza Logroño, Romina, additional, Sagñay, Juan C., additional, Faytong-Haro, Marco, additional, Robles-Velasco, Karla, additional, Zuberbier, Torsten, additional, and Maurer, Marcus, additional

Published
2024
Full Text
View/download PDF

4. [Translated article] Drug Survival in Cyclosporine Treatment for Moderate to Severe Atopic Dermatitis: Analysis of the Spanish Atopic Dermatitis Registry (BIOBADATOP)

Author

Couselo-Rodríguez, C., primary, Batalla, A., additional, Carrascosa, J.M., additional, Chicharro, P., additional, González-Quesada, A., additional, de la Cueva, P., additional, Giménez-Arnau, A.M., additional, Gilaberte, Y., additional, Rodríguez-Serna, M., additional, Montero-Vilchez, T., additional, Ruiz-Villaverde, R., additional, Elosua-González, M., additional, Silvestre-Salvador, J.F., additional, Munera-Campos, M., additional, Sánchez-Pérez, J., additional, Carretero, G., additional, Mauleón-Fernández, C., additional, Curto-Barredo, L., additional, Ballano-Ruiz, A., additional, Botella-Estrada, R., additional, Arias-Santiago, S., additional, Navarro-Triviño, F.J., additional, Roustan-Gullón, G., additional, Betlloch, I., additional, del Alcázar, E., additional, Abalde-Pintos, M.T., additional, Suárez-Perez, J., additional, García-Doval, I., additional, Descalzo, M.Á., additional, and Flórez, Á., additional

Published
2024
Full Text
View/download PDF

5. [Translated article] Four-year Epidemiological Surveillance of the Spanish Registry of Research in Contact Dermatitis and Cutaneous Allergy: Current Situation and Trends

Author

Tous-Romero, F., primary, Borrego-Hernando, L., additional, García-Doval, I., additional, Mercader-García, P., additional, Silvester-Salvador, J.F., additional, Sánchez-Gilo, A., additional, Sanz-Sánchez, T., additional, Giménez-Arnau, A.M., additional, Zaragoza-Ninet, V., additional, Miquel-Miquel, J., additional, González Pérez, R., additional, Córdoba-Guijarro, S., additional, Carrascosa-Carrillo, J.M., additional, Gática-Ortega, M.E., additional, Ruíz-González, I., additional, Serra-Baldrich, E., additional, Pastor-Nieto, A., additional, Rodríguez-Serna, M., additional, Sánchez-Pérez, J., additional, Melé i Ninot, G., additional, Sánchez-Pedreño Guillén, P., additional, and Ortiz-de Frutos, J., additional

Published
2024
Full Text
View/download PDF

6. Non-Skin-Related Symptoms are Common in Chronic Spontaneous Urticaria and Linked to Active and Uncontrolled Disease: Results from CURE

Author

Pyatilova, Polina, primary, Hackler, Yana, additional, Aulenbacher, Felix, additional, Asero, Riccardo, additional, Bauer, Andrea, additional, Bizjak, Mojca, additional, Day, Cascia, additional, Dissemond, Joachim, additional, Du-Thanh, Aurélie, additional, Fomina, Daria, additional, Giménez-Arnau, Ana M., additional, Grattan, Clive, additional, Gregoriou, Stamatis, additional, Hawro, Tomasz, additional, Kasperska-Zajac, Alicja, additional, Khoshkhui, Maryam, additional, Kocatürk, Emek, additional, Kovalkova, Elena, additional, Kulthanan, Kanokvalai, additional, Kuznetsova, Elizaveta, additional, Makris, Michael, additional, Mukhina, Olga, additional, Pesqué, David, additional, Peter, Jonny, additional, Salameh, Pascale, additional, Siebenhaar, Frank, additional, Sikora, Agnieszka, additional, Staubach, Petra, additional, Tuchinda, Papapit, additional, Zamłyński, Mateusz, additional, Weller, Karsten, additional, Maurer, Marcus, additional, and Kolkhir, Pavel, additional

Published
2024
Full Text
View/download PDF

8. Supervivencia de la ciclosporina en el tratamiento de la dermatitis atópica moderada-grave: Registro Español de Dermatitis Atópica (BIOBADATOP)

Author

Couselo-Rodríguez, C., primary, Batalla, A., additional, Carrascosa, J.M., additional, Chicharro, P., additional, González-Quesada, A., additional, de la Cueva, P., additional, Giménez-Arnau, A.M., additional, Gilaberte, Y., additional, Rodríguez-Serna, M., additional, Montero-Vilchez, T., additional, Ruiz-Villaverde, R., additional, Elosua-González, M., additional, Silvestre-Salvador, J.F., additional, Munera-Campos, M., additional, Sánchez-Pérez, J., additional, Carretero, G., additional, Mauleón-Fernández, C., additional, Curto-Barredo, L., additional, Ballano-Ruiz, A., additional, Botella-Estrada, R., additional, Arias-Santiago, S., additional, Navarro-Triviño, F.J., additional, Roustan-Gullón, G., additional, Betlloch, I., additional, del Alcázar, E., additional, Abalde-Pintos, M.T., additional, Suárez-Perez, J., additional, García-Doval, I., additional, Descalzo, M.Á., additional, and Flórez, Á., additional

Published
2024
Full Text
View/download PDF

9. Perfil epidemiológico, clínico y alérgico en pacientes con psoriasis. Evaluación del Registro Español de Dermatitis de Contacto (REIDAC)

Author

Verdaguer-Faja, J., primary, Borrego, L., additional, Mercader-García, P., additional, González Pérez, R., additional, Córdoba-Guijarro, S., additional, Giménez-Arnau, A.M., additional, Ruiz-González, I., additional, Miquel-Miquel, J., additional, Silvestre, J.F., additional, Ortiz de Frutos, F.J., additional, Tous-Romero, F., additional, Sanz Sánchez, T., additional, Rodríguez-Serna, M., additional, Sánchez-Pérez, J., additional, Serra Baldrich, E., additional, Zaragoza-Ninet, V., additional, Pastor-Nieto, M.A., additional, Gática-Ortega, M.E., additional, Sánchez Gilo, A., additional, Melé-Ninot, G., additional, Sánchez-Pedreño Guillén, P., additional, Munera-Campos, M., additional, Descalzo, M.Á., additional, García-Doval, I., additional, and Carrascosa, J.M., additional

Published
2024
Full Text
View/download PDF

10. Remibrutinib monotherapy reduced rescue medication in chronic spontaneous urticaria patients: Findings from a Phase 2b extension study

Author

Clore, Lee, primary, Carr, Warner, additional, Tillinghast, Jeffrey, additional, Jain, Vipul, additional, Reed, John, additional, Staubach, Petra, additional, Lheritier, Karine, additional, Walsh, Pauline, additional, Nikolaev, Ivan, additional, Haemmerle, Sibylle, additional, and Giménez-Arnau, Ana Maria, additional

Published
2024
Full Text
View/download PDF

11. Dupilumab in patients with chronic spontaneous urticaria (LIBERTY-CSU CUPID): Two randomized, double-blind, placebo-controlled, phase 3 trials

Author

Maurer, Marcus, primary, Casale, Thomas B., additional, Saini, Sarbjit S., additional, Ben-Shoshan, Moshe, additional, Giménez-Arnau, Ana M., additional, Bernstein, Jonathan A., additional, Yagami, Akiko, additional, Stjepanovic, Aleksandra, additional, Radin, Allen, additional, Staudinger, Heribert W., additional, Patel, Naimish, additional, Amin, Nikhil, additional, Akinlade, Bolanle, additional, Fan, Chunpeng, additional, Bauer, Deborah, additional, Yancopoulos, George D., additional, Patel, Kiran, additional, Mannent, Leda P., additional, and Laws, Elizabeth, additional

Published
2024
Full Text
View/download PDF

13. Vigilancia epidemiológica en los últimos 4 años del Registro Español de Investigación en Dermatitis de Contacto y Alergia Cutánea: situación actual y tendencias

Author

Tous-Romero, F., primary, Borrego-Hernando, L., additional, García-Doval, I., additional, Mercader-García, P., additional, Silvester-Salvador, J.F., additional, Sánchez-Gilo, A., additional, Sanz-Sánchez, T., additional, Giménez-Arnau, A.M., additional, Zaragoza-Ninet, V., additional, Miquel-Miquel, J., additional, González Pérez, R., additional, Córdoba-Guijarro, S., additional, Carrascosa-Carrillo, J.M., additional, Gática-Ortega, M.E., additional, Ruíz-González, I., additional, Serra-Baldrich, E., additional, Pastor-Nieto, A., additional, Rodríguez-Serna, M., additional, Sánchez-Pérez, J., additional, Melé i Ninot, G., additional, Sánchez-Pedreño Guillén, P., additional, and Ortiz-de Frutos, J., additional

Published
2023
Full Text
View/download PDF

19. Patients With Chronic Spontaneous Urticaria Who Have Wheals, Angioedema, or Both, Differ Demographically, Clinically, and in Response to Treatment—Results From CURE

Author

Buttgereit, Thomas, primary, Vera, Carolina, additional, Aulenbacher, Felix, additional, Church, Martin K., additional, Hawro, Tomasz, additional, Asero, Riccardo, additional, Bauer, Andrea, additional, Bizjak, Mojca, additional, Bouillet, Laurence, additional, Dissemond, Joachim, additional, Fomina, Daria, additional, Giménez-Arnau, Ana M., additional, Grattan, Clive, additional, Gregoriou, Stamatios, additional, Kulthanan, Kanokvalai, additional, Kasperska-Zajac, Alicja, additional, Kocatürk, Emek, additional, Makris, Michael, additional, Kolkhir, Pavel, additional, Weller, Karsten, additional, Magerl, Markus, additional, and Maurer, Marcus, additional

Published
2023
Full Text
View/download PDF

21. Remibrutinib demonstrates favorable safety profile and sustained efficacy in chronic spontaneous urticaria over 52 weeks

Author

Jain, Vipul, primary, Giménez-Arnau, Ana, additional, Hayama, Koremasa, additional, Reich, Adam, additional, Carr, Warner, additional, Tillinghast, Jeffrey, additional, Dahale, Swapnil, additional, Lheritier, Karine, additional, Walsh, Pauline, additional, Zharkov, Artem, additional, Hugot, Sophie, additional, and Haemmerle, Sibylle, additional

Published
2023
Full Text
View/download PDF

23. Severe perioperative anaphylaxis: Incidence in a tertiary hospital in Spain over a 20-year period. A historical cohort study

Author

F, Escolano, J, Yelamos, L, Moltó, B, Fort, M, Espona, and A, Giménez-Arnau

Subjects
General Medicine
Abstract

To assess the incidence of severe perioperative anaphylaxis, the mechanisms involved, the value of laboratory/skin tests, and the most effective treatments.A historical cohort study conducted in a tertiary public hospital in Spain. Patients that had undergone anaesthesia during the 20-year period were included. In these patients, 66 cases of severe anaphylaxis were found. In patients with suspicion of severe anaphylaxis, levels of blood histamine at less than 15 minutes and serum tryptase at 2, 6, and 24 hours following the reaction were determined. Skin and specific IgE tests were performed between 4 and 8 weeks later.Over the 20-year period, 288 594 anaesthetic procedures were performed. We observed cases of 66 severe anaphylaxis reaction (59% men; age, 60.8 ± 17.3 years. Symptoms observed were cardiovascular (86%), respiratory (73%), and mucocutaneous (56%). Elevated serum tryptase levels were associated with degree of severity at 2 (P 0.0001) and 6 hours (P = 0. 026) and were highest in IgE-mediated reactions (P = 0.020). All patients required treatment, and 3 events were fatal. In 84.8% of patients, skin and/or specific IgE tests were positive for antibiotics (35.8%), non-steroidal anti-inflammatory drugs (23.1%), neuromuscular blocking agents (15.4%) and latex (15.4%).The incidence of severe anaphylaxis in our hospital was 1 in 4.373 anaesthetic procedures, with a death rate of 4.5%. All cases required treatment. Serum tryptase was a good predictor of reaction severity. The most frequent causative agents were antibiotics, non-steroidal anti-inflammatory drugs, neuromuscular blocking agents and latex.

Published
2023

24. Urticaria exacerbations and adverse reactions in patients with chronic urticaria receiving COVID-19 vaccination: Results of the UCARE COVAC-CU study

Author

Kocatürk, Emek, primary, Salameh, Pascale, additional, Sarac, Esra, additional, Vera Ayala, Carolina E., additional, Thomsen, Simon Francis, additional, Zuberbier, Torsten, additional, Ensina, Luis Felipe, additional, Popov, Todor A., additional, van Doorn, Martijn B.A., additional, Giménez-Arnau, Ana Maria, additional, Asero, Riccardo, additional, Criado, Paulo Ricardo, additional, Aarestrup, Fernando M., additional, AbdulHameed Ansari, Zainab, additional, Al Abri, Salma, additional, Al Ahmad, Mona, additional, Al Hinai, Bushra, additional, Allenova, Anastasiia, additional, Al-Nesf, Maryam, additional, Altrichter, Sabine, additional, Arnaout, Rand, additional, Bartosińska, Joanna, additional, Bauer, Andrea, additional, Bernstein, Jonathan A., additional, Bizjak, Mojca, additional, Bonnekoh, Hanna, additional, Bouillet, Laurence, additional, Brzoza, Zenon, additional, Calvalcanti Dela Bianca Melo, Ana Caroline, additional, Campinhos, Fernanda L., additional, Carne, Emily, additional, Purayil, Saleema Cherichi, additional, Cherrez-Ojeda, Ivan, additional, Chong-Neto, Herberto Jose, additional, Christoff, George, additional, Conlon, Niall, additional, Jardim Criado, Roberta Fachini, additional, Cvenkel, Klara, additional, Damadoglu, Ebru, additional, Danilycheva, Inna, additional, Day, Cascia, additional, de Montjoye, Laurence, additional, Demir, Semra, additional, Ferucci, Silvia Mariel, additional, Fomina, Daria, additional, Fukunaga, Atsushi, additional, Garcia, Elizabeth, additional, Gelincik, Asli, additional, Göbel, Joe Hannah, additional, Godse, Kiran, additional, Gonçalo, Margarida, additional, Gotua, Maia, additional, Grattan, Clive, additional, Gugala, Agata, additional, Guillet, Carole, additional, Kalyoncu, Ali Fuat, additional, Karakaya, Gul, additional, Kasperska-Zając, Alicja, additional, Katelaris, Constance H., additional, Khoshkhui, Maryam, additional, Kleinheinz, Andreas, additional, Kolacinska-Flont, Marta, additional, Kolkhir, Pavel, additional, Košnik, Mitja, additional, Krasowska, Dorota, additional, Kumaran, Muthu Sendhil, additional, Kuprys-Lipinska, Izabela, additional, Kurowski, Marcin, additional, Kuznetsova, Elizaveta V., additional, Larenas-Linnemann, Désirée, additional, Lebedkina, Marina S., additional, Lee, Youngsoo, additional, Makris, Michael P., additional, Gómez, René Maximiliano, additional, Nasr, Iman, additional, Neisinger, Sophia, additional, Oda, Yoshiko, additional, Kara, Rabia Öztaş, additional, Palitot, Esther Bastos, additional, Papapostolou, Niki, additional, Salvador Parisi, Claudio Alberto, additional, Pesque, David, additional, Peter, Jonathan, additional, Petkova, Elena, additional, Ridge, Katie, additional, Rudenko, Michael, additional, Rutkowski, Krzysztof, additional, Saini, Sarbjit S., additional, Salman, Andac, additional, Sanchez, Jorge, additional, Şekerel, Bülent, additional, Serdotetskova, Sofia A., additional, Serpa, Faradiba S., additional, Dikicier, Bahar Sevimli, additional, Sidiropoulos, Nikitas, additional, Sikora, Agnieszka, additional, Sørensen, Jennifer Astrup, additional, Soria, Angele, additional, Kucuk, Ozlem Su, additional, Thalappil, Sherin Rahim, additional, Tomaszewska, Katarzyna, additional, Tuncay, Gulseren, additional, Unal, Derya, additional, Valle, Solange, additional, van Lindonk, Esmee, additional, Vestergaard, Christian, additional, Vitchuk, Aleksandr, additional, Xepapadaki, Paraskevi, additional, Ye, Young-Min, additional, Zalewska-Janowska, Anna, additional, Zamlynski, Mateusz, additional, and Maurer, Marcus, additional

Published
2023
Full Text
View/download PDF

33. Is There Any Relationship Between Chronic Urticaria, Its Severity and Alexithymia?

Author

Escalante Fiallos, Luis Miguel, primary, Ojeda, Ivan Cherrez, additional, Thomsen, Simon, additional, Giménez-Arnau, Ana, additional, Sørensen, Jennifer Astrup, additional, Godse, Kiran, additional, Guillet, Carole, additional, Maldonado Apolo, Astrid Karolina, additional, Chorzepa, Gonzalo, additional, Morfin-Maciel, Blanca, additional, Larco Sousa, Jose Ignacio, additional, De Arruda Chaves, Erika, additional, De, Abhishek, additional, Fomina, Daria, additional, Patil, Anant, additional, Criado, Roberta Jardim, additional, Ensina, Luis Felipe, additional, Valle, Solange, additional, Agondi, Rosana, additional, Neto, Herberto Chong, additional, Rosario, Nelson, additional, Ramon, German Dario, additional, Faytong-Haro, Marco, additional, Ogueta, Isabel, additional, Moran, Ivan Tinoco, additional, Cárdenas, Jaime, additional, Chabla, Mariana Tinoco, additional, Gavilanes, Sandy Aguilar, additional, Farinango Salazar, Victor Estuardo, additional, Huacon, Silvio Duran, additional, Donoso, Pablo Maldonado, additional, Muñoz, Nelson, additional, Gallardo, Johnny Gallardo, additional, Letterni, Damelis Martinez, additional, and Robles-Velasco, Karla, additional

Published
2023
Full Text
View/download PDF

34. The Benefit of Complete Response to Treatment in Patients With Chronic Spontaneous Urticaria—CURE Results

Author

Kolkhir, Pavel, primary, Laires, Pedro A., additional, Salameh, Pascale, additional, Asero, Riccardo, additional, Bizjak, Mojca, additional, Košnik, Mitja, additional, Dissemond, Joachim, additional, van Doorn, Martijn, additional, Hawro, Tomasz, additional, Kasperska-Zajac, Alicja, additional, Zajac, Magdalena, additional, Kocatürk, Emek, additional, Peter, Jonny, additional, Parisi, Claudio A.S., additional, Ritchie, Carla A., additional, Kulthanan, Kanokvalai, additional, Tuchinda, Papapit, additional, Fomina, Daria, additional, Kovalkova, Elena, additional, Khoshkhui, Maryam, additional, Kouzegaran, Samaneh, additional, Papapostolou, Niki, additional, Du-Thanh, Aurélie, additional, Kamegashira, Akiko, additional, Meshkova, Raisa, additional, Vitchuk, Alexander, additional, Bauer, Andrea, additional, Grattan, Clive, additional, Staubach, Petra, additional, Bouillet, Laurence, additional, Giménez-Arnau, Ana M., additional, Maurer, Marcus, additional, and Weller, Karsten, additional

Published
2023
Full Text
View/download PDF

37. [Artículo traducido] Práctica clínica diaria en el manejo de la urticaria crónica en España: resultados del estudio UCREX

Author

P. Terradas-Montana, M. Vidal-Jorge, J. Sastre Dominguez, J. Miquel-Miquel, A. Valero Santiago, F. J. Ortiz De Frutos, A. Giménez-Arnau, M. Ferrer Puga, J.F. Silvestre Salvador, I. Jáuregui Presa, Moises Labrador-Horrillo, and J. Bartra Tomàs

Subjects
Urticaria, Epidemiology, RL1-803, Autoimmunity, Dermatology, Quality-of-life, General Medicine, Angioedema, Internal medicine, RC31-1245
Abstract

Resumen: Antecedentes: La urticaria crónica (UC) es una enfermedad debilitante cuyo tratamiento es principalmente sintomático. El estudio UCREX tuvo como objetivo identificar el perfil de los pacientes con UC, el manejo de la enfermedad y la calidad de vida (CdV) en la práctica clínica diaria en España. Métodos: Estudio observacional, prospectivo, multicéntrico de 12 meses, que incluyó pacientes con UC de novo o establecida que acudieron a la consulta de dermatología/alergología de 39 hospitales españoles. Las variables principales fueron: el Urticaria Activity Score (UAS) y el UAS por siete días (UAS7). Las variables secundarias fueron: el cuestionario de CdV de urticaria crónica (CU-Q2oL), el EuroQol-5 Dimensiones (EQ-5D), la escala Medical Outcomes Study Sleep (MOS-Sleep) y la escala hospitalaria de ansiedad y depresión (HADS). Resultados: Se incluyeron 361 pacientes, de los cuales 176 (48,8%) formaron parte del análisis del objetivo principal. La edad media (DE) fue de 46,6 (14,2) años y el 71,8% eran del sexo femenino. El año anterior al periodo de inclusión de los pacientes, la mayoría de ellos (57,1%) se habían tratado con antihistamínicos H1 no sedantes (AHNS-H1). En la basal, se registró una media (DE) de 3,6 (6,8) de visitas a atención primaria. La media (DE) del UAS7 en la basal fue de 14,3 (11,0) y del CU-Q2oL 24,1 (17,0), observándose una tendencia en la mejoría en 8,6 (9,7) y 13,9 (15,0), respectivamente, a los 12 meses. El MOS-Sleep y el EQ-5D se mantuvieron estables durante el estudio, excepto por el dolor/malestar y la ansiedad/depresión que pasaron de 58,7 y 49,6% a 29,6 y 26,9%, respectivamente. En situación basal, el HADS mostró una ansiedad media (DE) de 8,7 (4,5) y una depresión de 5,1 (4,4), disminuyendo respectivamente a 7,0 (4,3) y 4,7 (4,3) a los 12 meses. Conclusiones: Aunque la mayoría de los pacientes son tratados con AHNS-H1, la actividad de la enfermedad sigue siendo importante, afectando negativamente a su CdV, su actividad laboral y repercutiendo negativamente en el uso de recursos sanitarios. Un manejo adecuado de la enfermedad podría ser la base para alcanzar el control de los síntomas, la mejora de la CdV y la optimización de los recursos sanitarios necesarios. Abstract: Background: Chronic Urticaria (CU) is a debilitating disease whose treatment is mainly symptomatic. UCREX study aimed to identify CU patients’ profile, disease management and quality-of-life (QoL) in daily clinical practice in Spain. Methods: Observational, 12-months prospective, multicenter study, included de novo or established CU patients attending to dermatology/allergy consultations in 39 Spanish hospitals. Main variables: Urticaria Activity Score (UAS), UAS over 7 days (UAS7). Secondary variables: CU-QoL Questionnaire (CU-Q2oL), EuroQol-5 dimensions (EQ-5D), Medical Outcomes Study Sleep (MOS-Sleep) scale, Hospital Anxiety and Depression Scale (HADS). Results: 361 patients included. Of them, 176 (48.8%) considered for the main objective analysis. Mean age (SD) of 46.6 (14.2) years and 71.8% women. The year prior to inclusion, most patients (57.1%) were treated with non-sedating H1-antihistamines (NS-H1AH). At baseline, mean (SD) 3.6 (6.8) visits were registered to primary care. Mean (SD) UAS7 at baseline was 14.3 (11.0) and CU-Q2oL 24.1 (17.0) which tended to improve by 8.6 (9.7) and 13.9 (15.0), respectively, at 12-months. MOS-Sleep and EQ-5D remained steady during the study, except pain/discomfort and anxiety/depression which went from 58.7% and 49.6% to 29.6% and 26.9%, respectively. At baseline, HADS showed a mean (SD) anxiety of 8.7 (4.5) and depression 5.1 (4.4), decreasing to 7.0 (4.3) and 4.7 (4.3), respectively, at 12-months. Conclusions: Although most CU patients are treated with NS-H1AH, disease activity is still important, negatively affecting patients’ QoL, work activity and healthcare resources use. An appropriate disease management could be the basis for symptoms control, QoL improvement and resources optimization.

Published
2022

40. L’inhibiteur de la tyrosine kinase de Bruton, rémibrutinib (LOU064), dans l’urticaire chronique spontanée: principaux résultats de l’étude de phase 2b

Author

Bérard, F., primary, Maurer, M., additional, Berger, W., additional, Giménez-Arnau, A., additional, Hayama, K., additional, Jain, V., additional, Reich, A., additional, Haemmerle, S., additional, Lheritier, K., additional, Walsh, P., additional, Xia, S., additional, and Storim, J., additional

Published
2022
Full Text
View/download PDF

44. Ligelizumab improves angioedema, disease severity and quality-of-life in patients with chronic spontaneous urticaria

Author

Metz, Martin, primary, Bernstein, Jonathan A., additional, Giménez-Arnau, Ana M., additional, Hide, Michihiro, additional, Maurer, Marcus, additional, Sitz, Karl, additional, Soong, Weily, additional, Sussman, Gordon, additional, Hua, Eva, additional, Barve, Avantika, additional, Barbier, Nathalie, additional, Balp, Maria-Magdalena, additional, and Severin, Thomas, additional

Published
2022
Full Text
View/download PDF

49. Contact Urticaria

Author

Giménez Arnau, Anna Maria and Maibach, Howard

Subjects
Protein contact dermatitis, Dermatitis, Occupational, Urticaria, Food, Immunology, Eczema, Humans, Immunology and Allergy, Dermatitis, Syndrome, Immediate contact reaction, Contact urticaria
Abstract

This article discusses contact urticaria syndrome definition, history, epidemiology, occupational relevance, mechanisms, clinical manifestations, diagnostic tools, agents responsible, and how to prevent and treat the patients affected. Contact urticaria syndrome is often misdiagnosed because it is not well known or recognized by physicians. Commonly the patient recognizes the cause of the clinical symptom, but the cause can be exceptional or new. Triggers include proteins, chemical compounds, agricultural chemicals, metals, plants, foods, and other substances. The objective of this article is to help dermatologists, toxicologists, and immunologists by providing diagnostic tools to avoid the culprit agent and treat the patients.

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results