50 results on '"Gooley, Paul R."'
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2. High yield expression and purification of full-length Neurotensin with pyroglutamate modification
3. Ligands selectively tune the local and global motions of neurotensin receptor 1 (NTS1)
4. The Monomeric α-Crystallin Domain of the Small Heat-shock Proteins αB-crystallin and Hsp27 Binds Amyloid Fibril Ends
5. The underlying sex differences in neuroendocrine adaptations relevant to Myalgic Encephalomyelitis Chronic Fatigue Syndrome
6. Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody
7. Structural Insights into the Unique Modes of Relaxin-Binding and Tethered-Agonist Mediated Activation of RXFP1 and RXFP2
8. Structural comparison of the C-terminal domain of functionally divergent lyssavirus P proteins
9. N- and C-terminal regions of αB-crystallin and Hsp27 mediate inhibition of amyloid nucleation, fibril binding, and fibril disaggregation
10. The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement
11. Probing the correlation between ligand efficacy and conformational diversity at the α1A-adrenoreceptor reveals allosteric coupling of its microswitches
12. Structural Elucidation of Viral Antagonism of Innate Immunity at the STAT1 Interface
13. Heteronuclear NMR spectroscopy of proteins encapsulated in cubic phase lipids
14. Multi-Component Mechanism of H2 Relaxin Binding to RXFP1 through NanoBRET Kinetic Analysis
15. The relaxin receptor as a therapeutic target – perspectives from evolution and drug targeting
16. Optimization and 13CH3 methionine labeling of a signaling competent neurotensin receptor 1 variant for NMR studies
17. Tadpole-like Conformations of Huntingtin Exon 1 Are Characterized by Conformational Heterogeneity that Persists regardless of Polyglutamine Length
18. The UBA domain of SnRK1 promotes activation and maintains catalytic activity
19. Molecular Insights into the Enigmatic Metabolic Regulator, SnRK1
20. Regulation of Starch Stores by a Ca2+-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii
21. The Recruitment of AMP-activated Protein Kinase to Glycogen Is Regulated by Autophosphorylation
22. Physical characterisation of high amylose maize starch and acylated high amylose maize starches
23. Investigation of Interactions at the Extracellular Loops of the Relaxin Family Peptide Receptor 1 (RXFP1)
24. Hydrodynamic radii of solubilized high amylose native and modified starches by pulsed field gradient NMR diffusion measurements
25. The Role of Select Subtype Polymorphisms on HIV-1 Protease Conformational Sampling and Dynamics
26. Esterification of high amylose starch with short chain fatty acids modulates degradation by Bifidobacterium spp.
27. The Relaxin Receptor (RXFP1) Utilizes Hydrophobic Moieties on a Signaling Surface of Its N-terminal Low Density Lipoprotein Class A Module to Mediate Receptor Activation
28. Membrane targeting of the small myristoylated protein 2 (SMP-2) in Leishmania major
29. Identification and characterization of bi-thiazole-2,2′-diamines as kinase inhibitory scaffolds
30. NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome
31. Acylation-dependent and-independent membrane targeting and distinct functions of small myristoylated proteins (SMPs) in Leishmania major
32. A Cyclic Peptide Inhibitor of ApoC-II Peptide Fibril Formation: Mechanistic Insight from NMR and Molecular Dynamics Analysis
33. AMP-Activated Protein Kinase β-Subunit Requires Internal Motion for Optimal Carbohydrate Binding
34. A Structural Model for Apolipoprotein C-II Amyloid Fibrils: Experimental Characterization and Molecular Dynamics Simulations
35. Recognition of Mitochondrial Targeting Sequences by the Import Receptors Tom20 and Tom22
36. Recognition and Detoxification of the Insecticide DDT by Drosophila melanogaster Glutathione S-Transferase D1
37. Membrane receptors: Structure and function of the relaxin family peptide receptors
38. A sample preparation protocol for 1H nuclear magnetic resonance studies of water-soluble metabolites in blood and urine
39. Thienopyridone Drugs Are Selective Activators of AMP-Activated Protein Kinase β1-Containing Complexes
40. Structure, topology and function of the translocase of the outer membrane of mitochondria
41. The Transmembrane Segment of Tom20 Is Recognized by Mim1 for Docking to the Mitochondrial TOM Complex
42. Probing the Flexibility of the DsbA Oxidoreductase from Vibrio cholerae—a 15N - 1H Heteronuclear NMR Relaxation Analysis of Oxidized and Reduced Forms of DsbA
43. High-level expression of a soluble and functional fibronectin type II domain from MMP-2 in the Escherichia coli cytoplasm for solution NMR studies
44. A Structural Core Within Apolipoprotein C-II Amyloid Fibrils Identified Using Hydrogen Exchange and Proteolysis
45. The NMR Solution Structure of the Relaxin (RXFP1) Receptor Lipoprotein Receptor Class A Module and Identification of Key Residues in the N-terminal Region of the Module That Mediate Receptor Activation
46. Convergent Evolution of Receptors for Protein Import into Mitochondria
47. Structure and Substrate-binding Mechanism of Human Ap4A Hydrolase
48. Patterns that Define the Four Domains Conserved in Known and Novel Isoforms of the Protein Import Receptor Tom20
49. The Structure of Ap4A Hydrolase Complexed with ATP-MgFx Reveals the Basis of Substrate Binding
50. The three-dimensional structure of the nudix enzyme diadenosine tetraphosphate hydrolase from Lupinus angustifolius L 1 1Edited by M. F. Summers
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