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Start Over Author "Han, Xiaosong" Publisher elsevier bv
11 results on '"Han, Xiaosong"'

3. Epigenomics analysis of miRNA cis-regulatory elements in pig muscle and fat tissues

Author

Hu, Mingyang, primary, Kuang, Renzhuo, additional, Guo, Yaping, additional, Ma, Ruixian, additional, Hou, Ye, additional, Xu, Yueyuan, additional, Qi, Xiaolong, additional, Wang, Daoyuan, additional, Zhou, Honghong, additional, Xiong, Youcai, additional, Han, Xiaosong, additional, Zhang, Jinfu, additional, Ruan, Jinxue, additional, Li, Xinyun, additional, Zhao, Shuhong, additional, Zhao, Yunxia, additional, and Xu, Xuewen, additional

Published
2022
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5. Lab in hydrogel portable kit: On-site monitoring of oxalate

Author

Jin, Rui, primary, Zhao, Lianjing, additional, Yan, Xu, additional, Han, Xiaosong, additional, Liu, Mengqi, additional, Chen, Yue, additional, Li, Qingyun, additional, Su, Dandan, additional, Liu, Fangmeng, additional, Sun, Peng, additional, Liu, Xiaomin, additional, Wang, Chenguang, additional, and Lu, Geyu, additional

Published
2020
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6. Metabolomic investigation of porcine muscle and fatty tissue after Clenbuterol treatment using gas chromatography/mass spectrometry

Author

Han Xiaosong, Yuhua Fu, Xinyun Li, Guanglei Li, and Changchun Li

Subjects
Male, 0301 basic medicine, Muscle tissue, Swine, Metabolite, Adipose tissue, 01 natural sciences, Biochemistry, Gas Chromatography-Mass Spectrometry, Analytical Chemistry, 03 medical and health sciences, chemistry.chemical_compound, Metabolomics, medicine, Animals, Clenbuterol, Amino Acids, Muscle, Skeletal, Chromatography, Fatty acid metabolism, Chemistry, Fatty Acids, 010401 analytical chemistry, Organic Chemistry, General Medicine, Adrenergic beta-Agonists, Animal Feed, 0104 chemical sciences, 030104 developmental biology, medicine.anatomical_structure, Adipose Tissue, Leucine, Gas chromatography–mass spectrometry, Biomarkers, medicine.drug
Abstract

Clenbuterol is a β-adrenergic agonist used as additive to increase the muscle mass of meat-producing animals. Previous studies were limited to evaluations of animal growth performance and determination of the residues. Several studies have focused on urine samples. Little information about the underlying molecular mechanisms that can explain Clenbuterol metabolism and promote energy repartition in animal muscle and fatty tissue is available. Therefore, this research aims to detect the metabolite variations in muscle and fatty tissue acquired from Chinese pigs fed with Clenbuterol using gas chromatography/mass spectrometry (GC/MS). Ten two-month old Enshi black pigs were fed under the same condition; five of which were fed with basic ration containing Clenbuterol for one month, whereas the other five pigs were fed only with basic ration. Muscle and fatty tissue were subjected to metabolomics analysis using GC/MS. Differences in metabolomic profiles between the two groups were characterized by multivariate statistical analysis. The muscle samples showed that 15 metabolites were significantly different in the Clenbuterol-treated group compared with the control group; 13 potential biomarkers were found in the fatty tissue. Most of the metabolites were associated with fatty acid metabolism and amino acid metabolism. Glycerol, phenylalanine, and leucine were the common metabolites between the muscle and fatty tissue. These metabolites may provide a new clue that contributes to the understanding of the energy reassignment induced by Clenbuterol.

Published
2016

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