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26 results on '"Haukvik, Unn K."'

1. Conduct disorder - a comprehensive exploration of comorbidity patterns, genetic and environmental risk factors

Author

Tesli, Natalia, primary, Jaholkowski, Piotr, additional, Haukvik, Unn K, additional, Jangmo, Andreas, additional, Haram, Marit, additional, Rokicki, Jaroslav, additional, Friestad, Christine, additional, Tielbeek, Jorim J, additional, Næss, Øyvind, additional, Skardhamar, Torbjørn, additional, Gustavson, Kristin, additional, Ask, Helga, additional, Fazel, Seena, additional, Tesli, Martin, additional, and Andreassen, Ole A, additional

Published
2023
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2. Mismatch negativity in schizophrenia spectrum and bipolar disorders: Group and sex differences and associations with symptom severity

Author

Pentz, Atle Bråthen, primary, Timpe, Clara Maria Fides, additional, Normann, Elizabeth Marie, additional, Slapø, Nora Berz, additional, Melle, Ingrid, additional, Lagerberg, Trine Vik, additional, Steen, Nils Eiel, additional, Westlye, Lars T., additional, Jönsson, Erik G., additional, Haukvik, Unn K., additional, Moberget, Torgeir, additional, Andreassen, Ole A., additional, and Elvsåshagen, Torbjørn, additional

Published
2023
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4. The age of violence: Mapping brain age in psychosis and psychopathy

Author

Tesli, Natalia, primary, Bell, Christina, additional, Hjell, Gabriela, additional, Fischer-Vieler, Thomas, additional, I Maximov, Ivan, additional, Richard, Genevieve, additional, Tesli, Martin, additional, Melle, Ingrid, additional, Andreassen, Ole A, additional, Agartz, Ingrid, additional, Westlye, Lars T, additional, Friestad, Christine, additional, Haukvik, Unn K, additional, and Rokicki, Jaroslav, additional

Published
2022
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5. Associations between amygdala nuclei volumes, psychosis, psychopathy, and violent offending

Author

Bell, Christina, primary, Tesli, Natalia, additional, Gurholt, Tiril P., additional, Rokicki, Jaroslav, additional, Hjell, Gabriela, additional, Fischer-Vieler, Thomas, additional, Melle, Ingrid, additional, Agartz, Ingrid, additional, Andreassen, Ole A., additional, Rasmussen, Kirsten, additional, Johansen, Ragnhild, additional, Friestad, Christine, additional, and Haukvik, Unn K., additional

Published
2022
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6. Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder : A Multisample Diffusion Tensor Imaging Study

Author

Tønnesen, Siren, Kaufmann, Tobias, de Lange, Ann-Marie G, Richard, Geneviève, Doan, Nhat Trung, Alnæs, Dag, van der Meer, Dennis, Rokicki, Jaroslav, Moberget, Torgeir, Maximov, Ivan I, Agartz, Ingrid, Aminoff, Sofie R, Beck, Dani, Barch, Deanna M, Beresniewicz, Justyna, Cervenka, Simon, Fatouros-Bergman, Helena, Craven, Alexander R, Flyckt, Lena, Gurholt, Tiril P, Haukvik, Unn K, Hugdahl, Kenneth, Johnsen, Erik, Jönsson, Erik G, Kolskår, Knut K, Kroken, Rune Andreas, Lagerberg, Trine V, Løberg, Else-Marie, Nordvik, Jan Egil, Sanders, Anne-Marthe, Ulrichsen, Kristine, Andreassen, Ole A, Westlye, Lars T, Tønnesen, Siren, Kaufmann, Tobias, de Lange, Ann-Marie G, Richard, Geneviève, Doan, Nhat Trung, Alnæs, Dag, van der Meer, Dennis, Rokicki, Jaroslav, Moberget, Torgeir, Maximov, Ivan I, Agartz, Ingrid, Aminoff, Sofie R, Beck, Dani, Barch, Deanna M, Beresniewicz, Justyna, Cervenka, Simon, Fatouros-Bergman, Helena, Craven, Alexander R, Flyckt, Lena, Gurholt, Tiril P, Haukvik, Unn K, Hugdahl, Kenneth, Johnsen, Erik, Jönsson, Erik G, Kolskår, Knut K, Kroken, Rune Andreas, Lagerberg, Trine V, Løberg, Else-Marie, Nordvik, Jan Egil, Sanders, Anne-Marthe, Ulrichsen, Kristine, Andreassen, Ole A, and Westlye, Lars T

Abstract

BACKGROUND: Schizophrenia (SZ) and bipolar disorder (BD) share substantial neurodevelopmental components affecting brain maturation and architecture. This necessitates a dynamic lifespan perspective in which brain aberrations are inferred from deviations from expected lifespan trajectories. We applied machine learning to diffusion tensor imaging (DTI) indices of white matter structure and organization to estimate and compare brain age between patients with SZ, patients with BD, and healthy control (HC) subjects across 10 cohorts. METHODS: We trained 6 cross-validated models using different combinations of DTI data from 927 HC subjects (18-94 years of age) and applied the models to the test sets including 648 patients with SZ (18-66 years of age), 185 patients with BD (18-64 years of age), and 990 HC subjects (17-68 years of age), estimating the brain age for each participant. Group differences were assessed using linear models, accounting for age, sex, and scanner. A meta-analytic framework was applied to assess the heterogeneity and generalizability of the results. RESULTS: Tenfold cross-validation revealed high accuracy for all models. Compared with HC subjects, the model including all feature sets significantly overestimated the age of patients with SZ (Cohen's d = -0.29) and patients with BD (Cohen's d = 0.18), with similar effects for the other models. The meta-analysis converged on the same findings. Fractional anisotropy-based models showed larger group differences than the models based on other DTI-derived metrics. CONCLUSIONS: Brain age prediction based on DTI provides informative and robust proxies for brain white matter integrity. Our results further suggest that white matter aberrations in SZ and BD primarily consist of anatomically distributed deviations from expected lifespan trajectories that generalize across cohorts and scanners.

Published
2020
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7. Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging Study

Author

Tønnesen, Siren, primary, Kaufmann, Tobias, additional, de Lange, Ann-Marie G., additional, Richard, Geneviève, additional, Doan, Nhat Trung, additional, Alnæs, Dag, additional, van der Meer, Dennis, additional, Rokicki, Jaroslav, additional, Moberget, Torgeir, additional, Maximov, Ivan I., additional, Agartz, Ingrid, additional, Aminoff, Sofie R., additional, Beck, Dani, additional, Barch, Deanna M., additional, Beresniewicz, Justyna, additional, Cervenka, Simon, additional, Fatouros-Bergman, Helena, additional, Craven, Alexander R., additional, Flyckt, Lena, additional, Gurholt, Tiril P., additional, Haukvik, Unn K., additional, Hugdahl, Kenneth, additional, Johnsen, Erik, additional, Jönsson, Erik G., additional, Kolskår, Knut K., additional, Kroken, Rune Andreas, additional, Lagerberg, Trine V., additional, Løberg, Else-Marie, additional, Nordvik, Jan Egil, additional, Sanders, Anne-Marthe, additional, Ulrichsen, Kristine, additional, Andreassen, Ole A., additional, Westlye, Lars T., additional, Farde, L., additional, Flyckt, L., additional, Engberg, G., additional, Erhardt, S., additional, Fatouros-Bergman, H., additional, Cervenka, S., additional, Schwieler, L., additional, Piehl, F., additional, Agartz, I., additional, Collste, K., additional, Victorsson, P., additional, Malmqvist, A., additional, Hedberg, M., additional, Orhan, F., additional, and Sellgren, C., additional

Published
2020
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10. Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium

Author

van Erp, Theo G.M., primary, Walton, Esther, additional, Hibar, Derrek P., additional, Schmaal, Lianne, additional, Jiang, Wenhao, additional, Glahn, David C., additional, Pearlson, Godfrey D., additional, Yao, Nailin, additional, Fukunaga, Masaki, additional, Hashimoto, Ryota, additional, Okada, Naohiro, additional, Yamamori, Hidenaga, additional, Bustillo, Juan R., additional, Clark, Vincent P., additional, Agartz, Ingrid, additional, Mueller, Bryon A., additional, Cahn, Wiepke, additional, de Zwarte, Sonja M.C., additional, Hulshoff Pol, Hilleke E., additional, Kahn, René S., additional, Ophoff, Roel A., additional, van Haren, Neeltje E.M., additional, Andreassen, Ole A., additional, Dale, Anders M., additional, Doan, Nhat Trung, additional, Gurholt, Tiril P., additional, Hartberg, Cecilie B., additional, Haukvik, Unn K., additional, Jørgensen, Kjetil N., additional, Lagerberg, Trine V., additional, Melle, Ingrid, additional, Westlye, Lars T., additional, Gruber, Oliver, additional, Kraemer, Bernd, additional, Richter, Anja, additional, Zilles, David, additional, Calhoun, Vince D., additional, Crespo-Facorro, Benedicto, additional, Roiz-Santiañez, Roberto, additional, Tordesillas-Gutiérrez, Diana, additional, Loughland, Carmel, additional, Carr, Vaughan J., additional, Catts, Stanley, additional, Cropley, Vanessa L., additional, Fullerton, Janice M., additional, Green, Melissa J., additional, Henskens, Frans A., additional, Jablensky, Assen, additional, Lenroot, Rhoshel K., additional, Mowry, Bryan J., additional, Michie, Patricia T., additional, Pantelis, Christos, additional, Quidé, Yann, additional, Schall, Ulrich, additional, Scott, Rodney J., additional, Cairns, Murray J., additional, Seal, Marc, additional, Tooney, Paul A., additional, Rasser, Paul E., additional, Cooper, Gavin, additional, Shannon Weickert, Cynthia, additional, Weickert, Thomas W., additional, Morris, Derek W., additional, Hong, Elliot, additional, Kochunov, Peter, additional, Beard, Lauren M., additional, Gur, Raquel E., additional, Gur, Ruben C., additional, Satterthwaite, Theodore D., additional, Wolf, Daniel H., additional, Belger, Aysenil, additional, Brown, Gregory G., additional, Ford, Judith M., additional, Macciardi, Fabio, additional, Mathalon, Daniel H., additional, O’Leary, Daniel S., additional, Potkin, Steven G., additional, Preda, Adrian, additional, Voyvodic, James, additional, Lim, Kelvin O., additional, McEwen, Sarah, additional, Yang, Fude, additional, Tan, Yunlong, additional, Tan, Shuping, additional, Wang, Zhiren, additional, Fan, Fengmei, additional, Chen, Jingxu, additional, Xiang, Hong, additional, Tang, Shiyou, additional, Guo, Hua, additional, Wan, Ping, additional, Wei, Dong, additional, Bockholt, Henry J., additional, Ehrlich, Stefan, additional, Wolthusen, Rick P.F., additional, King, Margaret D., additional, Shoemaker, Jody M., additional, Sponheim, Scott R., additional, De Haan, Lieuwe, additional, Koenders, Laura, additional, Machielsen, Marise W., additional, van Amelsvoort, Therese, additional, Veltman, Dick J., additional, Assogna, Francesca, additional, Banaj, Nerisa, additional, de Rossi, Pietro, additional, Iorio, Mariangela, additional, Piras, Fabrizio, additional, Spalletta, Gianfranco, additional, McKenna, Peter J., additional, Pomarol-Clotet, Edith, additional, Salvador, Raymond, additional, Corvin, Aiden, additional, Donohoe, Gary, additional, Kelly, Sinead, additional, Whelan, Christopher D., additional, Dickie, Erin W., additional, Rotenberg, David, additional, Voineskos, Aristotle N., additional, Ciufolini, Simone, additional, Radua, Joaquim, additional, Dazzan, Paola, additional, Murray, Robin, additional, Reis Marques, Tiago, additional, Simmons, Andrew, additional, Borgwardt, Stefan, additional, Egloff, Laura, additional, Harrisberger, Fabienne, additional, Riecher-Rössler, Anita, additional, Smieskova, Renata, additional, Alpert, Kathryn I., additional, Wang, Lei, additional, Jönsson, Erik G., additional, Koops, Sanne, additional, Sommer, Iris E.C., additional, Bertolino, Alessandro, additional, Bonvino, Aurora, additional, Di Giorgio, Annabella, additional, Neilson, Emma, additional, Mayer, Andrew R., additional, Stephen, Julia M., additional, Kwon, Jun Soo, additional, Yun, Je-Yeon, additional, Cannon, Dara M., additional, McDonald, Colm, additional, Lebedeva, Irina, additional, Tomyshev, Alexander S., additional, Akhadov, Tolibjohn, additional, Kaleda, Vasily, additional, Fatouros-Bergman, Helena, additional, Flyckt, Lena, additional, Busatto, Geraldo F., additional, Rosa, Pedro G.P., additional, Serpa, Mauricio H., additional, Zanetti, Marcus V., additional, Hoschl, Cyril, additional, Skoch, Antonin, additional, Spaniel, Filip, additional, Tomecek, David, additional, Hagenaars, Saskia P., additional, McIntosh, Andrew M., additional, Whalley, Heather C., additional, Lawrie, Stephen M., additional, Knöchel, Christian, additional, Oertel-Knöchel, Viola, additional, Stäblein, Michael, additional, Howells, Fleur M., additional, Stein, Dan J., additional, Temmingh, Henk S., additional, Uhlmann, Anne, additional, Lopez-Jaramillo, Carlos, additional, Dima, Danai, additional, McMahon, Agnes, additional, Faskowitz, Joshua I., additional, Gutman, Boris A., additional, Jahanshad, Neda, additional, Thompson, Paul M., additional, Turner, Jessica A., additional, Farde, Lars, additional, Engberg, Göran, additional, Erhardt, Sophie, additional, Cervenka, Simon, additional, Schwieler, Lilly, additional, Piehl, Fredrik, additional, Collste, Karin, additional, Victorsson, Pauliina, additional, Malmqvist, Anna, additional, Hedberg, Mikael, additional, and Orhan, Funda, additional

Published
2018
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15. Interplay between childhood trauma and BDNF val66met variants on blood BDNF mRNA levels and on hippocampus subfields volumes in schizophrenia spectrum and bipolar disorders

Author

Aas, Monica, primary, Haukvik, Unn K., additional, Djurovic, Srdjan, additional, Tesli, Martin, additional, Athanasiu, Lavinia, additional, Bjella, Thomas, additional, Hansson, Lars, additional, Cattaneo, Annamaria, additional, Agartz, Ingrid, additional, Andreassen, Ole A., additional, and Melle, Ingrid, additional

Published
2014
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17. Reduced brain cortical folding in schizophrenia revealed in two independent samples

Author

Nesvåg, Ragnar, primary, Schaer, Marie, additional, Haukvik, Unn K., additional, Westlye, Lars T., additional, Rimol, Lars M., additional, Lange, Elisabeth H., additional, Hartberg, Cecilie B., additional, Ottet, Marie-Christine, additional, Melle, Ingrid, additional, Andreassen, Ole A., additional, Jönsson, Erik G., additional, Agartz, Ingrid, additional, and Eliez, Stephan, additional

Published
2014
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18. BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses

Author

Aas, Monica, primary, Haukvik, Unn K., additional, Djurovic, Srdjan, additional, Bergmann, Ørjan, additional, Athanasiu, Lavinia, additional, Tesli, Martin S., additional, Hellvin, Tone, additional, Steen, Nils Eiel, additional, Agartz, Ingrid, additional, Lorentzen, Steinar, additional, Sundet, Kjetil, additional, Andreassen, Ole A., additional, and Melle, Ingrid, additional

Published
2013
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19. No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes

Author

Tesli, Martin, primary, Egeland, Randi, additional, Sønderby, Ida E., additional, Haukvik, Unn K., additional, Bettella, Francesco, additional, Hibar, Derrek P., additional, Thompson, Paul M., additional, Rimol, Lars Morten, additional, Melle, Ingrid, additional, Agartz, Ingrid, additional, Djurovic, Srdjan, additional, and Andreassen, Ole A., additional

Published
2013
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20. ZNF804A and cortical thickness in schizophrenia and bipolar disorder

Author

Bergmann, Ørjan, primary, Haukvik, Unn K., additional, Brown, Andrew A., additional, Rimol, Lars M., additional, Hartberg, Cecilie B., additional, Athanasiu, Lavinia, additional, Melle, Ingrid, additional, Djurovic, Srdjan, additional, Andreassen, Ole A., additional, Dale, Anders M., additional, and Agartz, Ingrid, additional

Published
2013
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22. Cortical Volume, Surface Area, and Thickness in Schizophrenia and Bipolar Disorder

Author

Rimol, Lars M., primary, Nesvåg, Ragnar, additional, Hagler, Don J., additional, Bergmann, Ørjan, additional, Fennema-Notestine, Christine, additional, Hartberg, Cecilie B., additional, Haukvik, Unn K., additional, Lange, Elisabeth, additional, Pung, Chris J., additional, Server, Andres, additional, Melle, Ingrid, additional, Andreassen, Ole A., additional, Agartz, Ingrid, additional, and Dale, Anders M., additional

Published
2012
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24. Cortical Thickness and Subcortical Volumes in Schizophrenia and Bipolar Disorder

Author

Rimol, Lars M., primary, Hartberg, Cecilie B., additional, Nesvåg, Ragnar, additional, Fennema-Notestine, Christine, additional, Hagler, Donald J., additional, Pung, Chris J., additional, Jennings, Robin G., additional, Haukvik, Unn K., additional, Lange, Elisabeth, additional, Nakstad, Per H., additional, Melle, Ingrid, additional, Andreassen, Ole A., additional, Dale, Anders M., additional, and Agartz, Ingrid, additional

Published
2010
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26. REDUCED BRAIN CORTICAL FOLDING IN SCHIZOPHRENIA

Author

Nesvåg, Ragnar, primary, Schaer, Marie, additional, Haukvik, Unn K., additional, Rimol, Lars M., additional, Lange, Elisabeth H., additional, Hartberg, Cecilie B., additional, Jönsson, Erik G., additional, Melle, Ingrid, additional, Andreassen, Ole A., additional, Agartz, Ingrid, additional, and Eliez, Stephan, additional

Published
2010
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