65 results on '"Jingya Wang"'
Search Results
2. A novel transient thermal circuit model of buried power cables for emergency and dynamic load
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Jingya Wang, Yongchun Liang, and Chunyu Ma
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General Energy - Published
- 2023
3. Phase equilibria of long-period stacking ordered phase in the ternary Mg-Y-Al alloys
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Yiwen Chen, Quan Li, Yangxin Li, Weisen Zheng, Jingya Wang, and Xiaoqin Zeng
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Polymers and Plastics ,Mechanics of Materials ,Mechanical Engineering ,Materials Chemistry ,Metals and Alloys ,Ceramics and Composites - Published
- 2022
4. The phosphorylation of serine55 in enamelin is essential for murine amelogenesis
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Changchun Dong, Bikash Lamichhane, Hajime Yamazaki, Brent Vasquez, Jingya Wang, Yongxu Zhang, Jian Q. Feng, Henry C. Margolis, Elia Beniash, and Xiaofang Wang
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Molecular Biology - Published
- 2022
5. Characterization on the formation of porosity and tensile properties prediction in die casting Mg alloys
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Jingya Wang, Zixin Li, Bo Hu, Xingfeng Zhao, Ming Qin, Wenke Zhou, Xiaoqin Zeng, Jiangkun Xu, and Dejiang Li
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010302 applied physics ,Materials science ,Alloy ,Metals and Alloys ,02 engineering and technology ,engineering.material ,021001 nanoscience & nanotechnology ,01 natural sciences ,Die casting ,Stress (mechanics) ,Mechanics of Materials ,Casting (metalworking) ,0103 physical sciences ,Ultimate tensile strength ,engineering ,Fracture (geology) ,Coupling (piping) ,Composite material ,0210 nano-technology ,Porosity - Abstract
The 3D visualization of the porosity in high-pressure die casting (HPDC) Mg alloys AZ91D and Mg4Ce2Al0.5Mn (EA42) was investigated by X-ray computed tomography. It was demonstrated that the volumetric porosity at the near-gate location for alloy EA42 was significantly higher than that far from the gate location. This difference resulted from the low valid time during intensified casting pressure conditions. Specimens of alloy EA42 exhibited a narrow pore distribution in the side view (∼0.5 mm) compared to the wide distribution (∼1.8 mm) of alloy AZ91D, which was mainly attributed to the formation mechanism of the defect band. The formation of microporosity in the defect band of alloy EA42 was inhibited because of the significant latent heat released by a large amount of the Al11Ce3 phase segregated in the defect band during solidification. Additionally, an effective estimator (Z-Propagation) was introduced, which is proposed to predict the projected area fraction of the porosity (f) involved during tensile failure with better effectiveness compared with traditional methods based on the actual fractured surface. By coupling the Z-Propagation method with the critical local strain model, the logarithmic fracture strain and true fracture stress of the specimens were predicted within 3.03% and 1.65% of the absolute value of the average relative error (AARE), respectively.
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- 2022
6. LS-LSTM-AE: Power load forecasting via Long-Short series features and LSTM-Autoencoder
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Xin Tong, Jingya Wang, Changlin Zhang, Teng Wu, Haitao Wang, and Yu Wang
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Load forecasting ,General Energy ,Deep learning ,Autoencoder ,Electrical engineering. Electronics. Nuclear engineering ,LSTM ,Unsupervised learning ,Supervised learning ,TK1-9971 - Abstract
Aiming at weak representation ability and severe loss of time series features in the traditional methods when facing large-scale and complex power load forecasting tasks, an LSTM-Autoencoder model that integrates long-term and short-term features of the samples is proposed for load forecasting. The encoder part simultaneously receives long time series and short time series as input to extract time series features of different levels and generate related latent vectors. The decoder tries to reconstruct the input sequence while outputting the prediction results to ensure that the latent vectors are meaningful. In addition, the model also uses a mixture of supervised and unsupervised training methods. Experiments based on a publicly available dataset from Alberta Electric System Operator showed that the method presented in this research is superior to many existing mainstream methods, with a mean absolute error of less than 52MW between the prediction results and the actual load values.
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- 2022
7. Thermodynamic Modelling for the Long-Period Stacking Ordered Phase in Mg–Y–Al System: Construction and Application
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Yiwen Chen, Mingdi Yu, Jingya Wang, Quan Li, Weisen Zheng, Jianbo Li, and Xiaoqin Zeng
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- 2023
8. Oh-Former: Omni-Relational High-Order Transformer for Occluded Person Re-Identification
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Xianing Chen, Chunlin Yu, Jialang Xu, Qiong Cao, Jingya Wang, and Shenghua Gao
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- 2023
9. The risk of mental illness in people living with HIV in the UK: a propensity score-matched cohort study
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Tiffany E Gooden, Mike Gardner, Jingya Wang, Joht S Chandan, Abi Beane, Rashan Haniffa, Stephen Taylor, Sheila Greenfield, Semira Manaseki-Holland, G Neil Thomas, and Krishnarajah Nirantharakumar
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Infectious Diseases ,Epidemiology ,Virology ,Immunology - Published
- 2022
10. Facile synthesis of 2D MoS2/reduced graphene oxide hybrids with excellent microwave absorption
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Min Zhang, Ruotong Zhu, Cheng Qian, Jingya Wang, Zhengzhou Jin, Yongxing Zhang, Weiwei Zhang, and Qiangchun Liu
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Mechanics of Materials ,Mechanical Engineering ,Materials Chemistry ,Metals and Alloys - Published
- 2023
11. Regulating corrosion resistance of Mg alloys via promoting precipitation with trace Zr alloying
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Yuyang Chen, Tao Ying, Yao Yang, Jingya Wang, and Xiaoqin Zeng
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General Chemical Engineering ,General Materials Science ,General Chemistry - Published
- 2023
12. Changes in soil bacterial and fungal community characteristics in response to long-term mulched drip irrigation in oasis agroecosystems
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Jingya Wang, Haiqiang Li, Zhibo Cheng, Fating Yin, Lei Yang, and Zhenhua Wang
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Soil Science ,Agronomy and Crop Science ,Earth-Surface Processes ,Water Science and Technology - Published
- 2023
13. Research on fast real-time calculation model for transient temperature rise of power cables in ducts
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Chenzhao Fu, Qingquan Li, Jingya Wang, Zhao Ziyu, Liang Yongchun, and Ying Sun
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Materials science ,020209 energy ,Lumped parameter model ,02 engineering and technology ,Mechanics ,Transient temperature ,Thermal circuit ,Power (physics) ,Thermal circuit model ,General Energy ,Cable core temperature ,020401 chemical engineering ,Fast calculation ,Power cables in duct ,0202 electrical engineering, electronic engineering, information engineering ,Power cable ,Duct (flow) ,lcsh:Electrical engineering. Electronics. Nuclear engineering ,Transient (oscillation) ,0204 chemical engineering ,lcsh:TK1-9971 - Abstract
A straightforward and fast transient temperature rise calculation model is necessary for electrical engineers to manage power cable load. A self-heating lumped parameter model (LPM) without the requirement of monitoring cable surface temperature is developed to evaluate the real-time transient temperature rise of the power cable in ducts. A mutual-heating lumped parameter model to describe the mutual heat interaction between any two cables is proposed in this paper as well. The transient temperature rise of any power cable in duct is the sum of the self-heating temperature rise and the mutual-heating temperature rise from all the other power cables in ducts. All parameters of these two models are obtained by transient thermal circuit analysis, CYMCAP calculation results and generic algorithm. A case study has been conducted to verify the feasibility of the proposed LPMs and the self and mutual temperature rise for each cable in ducts have been obtained. These results agree with the accurate data obtained from CYMCAP well, indicating that LPM can be used as a fast and straightforward tool to calculate the transient temperature rise of power cables in duct.
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- 2021
14. Radiogenic Nd in bioapatite from rare earth elements rich deep sea sediments from Central Indian Oceanic Basin and its implication in material sources
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Xiaoyu Zhang, Yanfang Lu, Yu Miao, Mu Huang, Kongyang Zhu, Luyi Cai, Jingya Wang, and Xuefa Shi
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Geochemistry and Petrology ,Economic Geology ,Geology - Published
- 2023
15. Electrochemical Corrosion Behavior of Mg-Al Alloy with Micro-Alloying of Yttrium in a Chloride Solution
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Yao Yang, Tao Ying, Fuyong Cao, Jingya Wang, Qingchun Zhu, and Xiaoqin Zeng
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- 2022
16. Cross-Domain Multi-Style Merge for Image Captioning
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Yiqun Duan, Zhen Wang, Yi Li, and Jingya Wang
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History ,Polymers and Plastics ,Signal Processing ,Computer Vision and Pattern Recognition ,Business and International Management ,Software ,Industrial and Manufacturing Engineering - Published
- 2022
17. Soil aggregation and aggregate-associated organic carbon under typical natural halophyte communities in arid saline areas of Northwest China
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Jingya Wang, Haichang Yang, Fenghua Zhang, Zhibo Cheng, and William J. Gale
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Haloxylon ammodendron ,Soil salinity ,biology ,Tamarix ,Soil Science ,Plant community ,04 agricultural and veterinary sciences ,Soil carbon ,010502 geochemistry & geophysics ,biology.organism_classification ,01 natural sciences ,Arid ,Agronomy ,Halophyte ,Botany ,040103 agronomy & agriculture ,0401 agriculture, forestry, and fisheries ,Ammodendron ,Environmental science ,0105 earth and related environmental sciences - Abstract
Information on the effects of halophyte communities on soil organic carbon (SOC) is useful for sequestrating C in arid regions. In this study, we identified four typical natural halophyte communities in the Manasi River Basin in Xinjiang Province, Northeast China, namely, Karelinia caspia (Pall.) Less., Bassia dasyphylla (Fisch. et C. A. Mey.) Kuntze, Haloxylon ammodendron (C. A. Mey.) Bunge, and Tamarix ramosissima Lour. We compared soil aggregation and aggregated-associated SOC under these communities. The aggregate fraction of 0.053–0.25 mm accounted for 47%–75% of the total soil mass, significantly more than the > 0.25 and 0.25 mm aggregates (13.3%–43.8%) and T. ramosissima community having more 0.25 mm fraction, followed by the T. ramosissima (4.9 g kg−1) > K. caspia (4.2 g kg−1) > B. dasyphylla (3.4 g kg−1). The H. ammodendron community had the highest total SOC and aggregate-associated SOC, which was primarily because aggregate-associated SOC content at the 0–10 and 10–20 cm depths under this community were higher than those under other plant communities. The H. ammodendron community could be beneficial for increasing SOC in saline soils in the arid region.
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- 2020
18. Catalytic PtPd bimetal nanocrystals with high-index facets for radiation injury repair
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Xiaodong Zhang, Fujuan Xu, Wei Long, Jingya Wang, Yuan-Ming Sun, Junying Wang, Hongying Wu, and Mu Xiaoyu
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Chemistry ,business.industry ,medicine.medical_treatment ,Cancer ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,medicine.disease ,01 natural sciences ,0104 chemical sciences ,Catalysis ,Bimetal ,Radiation therapy ,Nanocrystal ,In vivo ,medicine ,Biophysics ,Radiation protection ,0210 nano-technology ,business ,Survival rate - Abstract
Radiotherapy is one of the most important clinical cancer treatments, which works mainly by delivering a prescribed radiation dose to the tumor tissues. However, high doses of radiation may also lead many irreversible damages to the surrounding normal tissues. Thereby, how to effectively reduce these side-effects has been a significant factor in influencing cancer therapeutic effect. In this work, we synthesized the hollow PtPd nanocubes with high-index facets, and investigated the radiation protection capability in vitro and in vivo. Our results showed the PtPd nanocrystals can decrease the ROS level and improve the survival rate of radiated cells. Meanwhile, survival rate of radiated mice can significantly increase from 0 to 30% after PtPd treatment. Consequently, the enzyme and ROS level in radiated mice can be recovered.
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- 2020
19. Renewable and flexible UV-blocking film from poly(butylene succinate) and lignin
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Xin Zhou, Jingya Wang, Shaozhong Peng, Fudong Bai, Xiangchen Fang, Shumin Zhou, and Yan Zhang
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Materials science ,Polymers and Plastics ,Organic Chemistry ,Plasticizer ,General Physics and Astronomy ,Maleic anhydride ,02 engineering and technology ,Compatibilization ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Miscibility ,Bioplastic ,0104 chemical sciences ,Polybutylene succinate ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,Materials Chemistry ,Lignin ,Biocomposite ,0210 nano-technology - Abstract
Herein, a renewable and flexible UV-shielding biocomposite film was obtained by poly(butylene succinate) (PBS) and lignin. A strategy of reactive interfacial compatibilization was developed in order to improve the miscibility of lignin with PBS. Firstly, lignin was modified by maleic anhydride, and then the reactive plasticizer triethy citrate (TEC) was employed as a bridge to reinforce the interaction of lignin with PBS. The elongation at break and the Young’s modulus of the films were evaluated at a maximum of 208% and 129 MPa respectively at the lignin content of 20% and TEC content of 5%, indicating the excellent enhanced flexibility. The miscibility of the lignin was rationalized through the analysis of SEM, DSC, and FT-IR. Exceptionally, the films could block against 100% UV light and degrade absolutely in different compositions. Conclusively, the strategy opens up novel approaches to expand the accessibility of lignin to renewable bioplastics.
- Published
- 2019
20. Upconversion color tunability and white light generation in Yb3+/Er3+/Tm3+ tri-doped CaF2 single crystals
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Jingshan Hou, Bo Zhang, Xiaobo Qian, Xueyuan Chen, Yongzheng Fang, Liangbi Su, Lili Zheng, and Jingya Wang
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Diffraction ,Materials science ,Laser diode ,Organic Chemistry ,Doping ,Analytical chemistry ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Fluorescence ,Atomic and Molecular Physics, and Optics ,Photon upconversion ,Spectral line ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,law.invention ,Inorganic Chemistry ,law ,Electrical and Electronic Engineering ,Physical and Theoretical Chemistry ,0210 nano-technology ,Absorption (electromagnetic radiation) ,Single crystal ,Spectroscopy - Abstract
Yb3+/Er3+/Tm3+ tri-doped CaF2 single crystals have been successfully synthesized via Temperature Gradient Technique (TGT) method, and represented by X-ray diffraction (XRD) examination, absorption and fluorescence spectrum, pump power dependence and lifetime analysis in details. Under the excitation of 980 nm laser diode (LD), the upconversion luminescence (UCL) spectra of Yb3+/Er3+/Tm3+/CaF2 as a function of Tm3+ concentration are made up of intense blue (Tm3+:1G4 → 3H6), green (Er3+: 4S3/2, 2H11/2 → 4I15/2), and red (Er3+:4F9/2 → 4I15/2) emissions, which are located at 478, 523, 539 and 656 nm, respectively. With increasing concentration of Tm, the color can be tunable from orange-yellow, white to blue light. And the optimal Yb3+/Er3+/Tm3+ doping concentrations for white light are determined to be 10%Yb, 0.1%Er and 0.05%Tm. The research indicates that the as-prepared materials may have potential applications in the fields of three dimensional displays, back lighting, white light sources, and so on.
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- 2019
21. Spectral properties and highly efficient continuous-wave laser operation in Nd, Gd:CaF2 crystals
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Liangbi Su, Siyuan Pang, Shaozhao Wang, Jie Liu, Jingya Wang, Xiaobo Qian, Dapeng Jiang, Qinghui Wu, and Bingchu Mei
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Materials science ,Mechanical Engineering ,Doping ,Slope efficiency ,Spectral properties ,Metals and Alloys ,Analytical chemistry ,02 engineering and technology ,Cw laser ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Laser ,01 natural sciences ,0104 chemical sciences ,law.invention ,Mechanics of Materials ,law ,Materials Chemistry ,Continuous wave ,0210 nano-technology - Abstract
Spectral properties of Nd, Gd:CaF2 crystals were investigated. In comparison with Nd:CaF2, the spectral parameters of Nd, Gd:CaF2 were altered in a large scale. LD-pumped true CW laser has been demonstrated in the crystals. The slope efficiency with the value of 45% in 0.5 at.% Nd, 5 at.% Gd:CaF2 was achieved, it is the highest slope efficiency in Nd doped CaF2 single crystals by LD-pumping. The system is a promising candidate for highly efficient lasers.
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- 2019
22. Photoluminescence property and widely tunable, efficient 2μm laser in Tm:Ca1−xGdxF2+x single crystals
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Yuqiang Zu, Cheng Zhang, Jie Liu, Dapeng Jiang, Liangbi Su, Xiaobo Qian, Jingya Wang, Xinsheng Guo, and Bingchu Mei
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Materials science ,Birefringence ,Photoluminescence ,business.industry ,Slope efficiency ,Spectral properties ,Analytical chemistry ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Laser ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,law.invention ,Ion ,010309 optics ,Optics ,law ,Lattice (order) ,0103 physical sciences ,Electrical and Electronic Engineering ,Physical and Theoretical Chemistry ,0210 nano-technology ,business ,Quartz - Abstract
3at.%Tm 3 + :Ca 1 − x Gd x F 2 + x ( x = 0 , 0.005, 0.01, 0.02) single crystals were grown by the vertical Bridgman method, where Gd 3 + ions play the role of manipulating ions for local structure to form a disordered lattice site. Spectral properties of these crystals were investigated. Compared to 3at.%Tm 3 + :CaF2, the spectral parameters of 3at.%Tm 3 + :Ca 1 − x Gd x F 2 + x were drastically enhanced in a large scale. LD pumped lasers have been demonstrated in the crystals for the first time. For CW operation, the slope efficiency up to 49.7% was achieved with output power of 1.927 W at 1970 nm. With a birefringent quartz plate, wavelength-tunable laser operation with a tuning range of more than 176 nm was realized.
- Published
- 2019
23. Snapshot time-reversed ultrasonically encoded optical focusing guided by time-reversed photoacoustic wave
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Juze, Zhang, Zijian, Gao, Jingyan, Zhang, Peng, Ge, Feng, Gao, Jingya, Wang, and Fei, Gao
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Radiology, Nuclear Medicine and imaging ,Atomic and Molecular Physics, and Optics - Abstract
Deep-tissue optical imaging is a longstanding challenge limited by scattering. Both optical imaging and treatment can benefit from focusing light in deep tissue beyond one transport mean free path. Wavefront shaping based on time-reversed ultrasonically encoded (TRUE) optical focusing utilizes ultrasound focus, which is much less scattered than light in biological tissues as the 'guide star'. However, the traditional TRUE is limited by the ultrasound focusing area and pressure tagging efficiency, especially in acoustically heterogeneous medium. Even the improved version of iterative TRUE comes at a large time consumption, which limits the application of TRUE. To address this problem, we proposed a method called time-reversed photoacoustic wave guided time-reversed ultrasonically encoded (TRPA-TRUE) optical focusing by integrating accurate ultrasonic focusing through acoustically heterogeneous medium guided by time-reversing PA signals, and the ultrasound modulation of diffused coherent light with optical phase conjugation (OPC), achieving dynamic focusing of light into scattering medium. Simulation results show that the focusing accuracy of the proposed method has been significantly improved compared with conventional TRUE, which is more suitable for practical applications that suffers severe acoustic distortion, e.g. transcranial optical focusing.
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- 2022
24. Investigation of anodized Ta/Ag coating on magnesium bipolar plate for lightweight proton exchange membrane fuel cells
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Pengfei Yan, Tao Ying, Yao Yang, Fuyong Cao, Yangxin Li, Jingya Wang, and Xiaoqin Zeng
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General Chemical Engineering ,General Materials Science ,General Chemistry - Published
- 2022
25. The Association of Cardiovascular Risk Factors and Disease in People With HIV in the UK: A Retrospective Matched Cohort Study
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Tiffany E. Gooden, Mike Gardner, Jingya Wang, Kate Jolly, Deirdre A. Lane, Laura Benjamin, Henry C. Mwandumba, Vanessa Kandoole, Isaac B. Lwanga, Stephen Taylor, Semira Manaseki-Holland, Gregory Lip, Krishnarajah Nirantharakumar, and G. Neil Thomas
- Published
- 2021
26. Micro-compression of Al2Ca particles in a Mg-Al-Ca alloy
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Shunzi Luo, Leyun Wang, Jingya Wang, Gaoming Zhu, and Xiaoqin Zeng
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General Materials Science - Published
- 2022
27. Effect of Sc microalloying on microstructure evolution and mechanical properties of extruded Al–Zn–Mg–Cu alloys
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Xiaoqin Zeng, Gu Lidong, Tang Xiaoyi, Jingya Wang, and Tao Ying
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Equiaxed crystals ,Materials science ,Scanning electron microscope ,Mechanical Engineering ,Recrystallization (metallurgy) ,Condensed Matter Physics ,Microstructure ,law.invention ,Optical microscope ,Mechanics of Materials ,law ,Ultimate tensile strength ,General Materials Science ,Extrusion ,Composite material ,Electron backscatter diffraction - Abstract
The effect of microalloying Sc on the microstructure and mechanical properties of Al–Zn–Mg–Cu alloys was experimentally investigated through X-ray diffraction, optical microscopy, scanning electron microscopy, electron backscatter diffraction, and transmission electron microscopy characterizations and tensile tests. The presence of Sc caused the formation of the primary Al3Sc phase and behaved a significant modifying effect on the cast microstructure with an equiaxed microstructure attained in the Sc-bearing alloys rather than the dendrites in Sc-free alloys. In the subsequent thermal extrusion processing, a remarkable grain refinement and retardation of recrystallization occurred, because the nano-sized Al3Sc dispersoids contributed to the pinning effect on the dislocation movement and grain boundary migration in the Sc-bearing alloys. The mechanical properties were significantly improved with the addition of Sc. The superior comprehensive mechanical properties in the Sc-bearing alloys were achieved via the optimal extrusion at 350 °C with the yield strength and ultimate tensile strength of 373.7 ± 3 MPa and 490.3 ± 5 MPa, respectively. The strong strengthening behavior of the Sc addition in the extruded alloys is mainly attributed to the grain refinement and the dispersoid strengthening from the Al3Sc particles. The corresponding contributions to the increase in yield strength derived from the grain refinement and the dispersoid strengthening were estimated, which indicated that the highest particle density attained by extrusion at 350 °C resulted in the excellent mechanical properties of the Sc-bearing alloys.
- Published
- 2022
28. Experimental investigation and thermodynamic modeling of the ternary Ti–Fe–Mn system for hydrogen storage applications
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Tong Wu, Xiao-Gang Lu, Jingya Wang, Weisen Zheng, Yanlin He, and Wei Song
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Ternary numeral system ,Materials science ,Mechanical Engineering ,Metals and Alloys ,Intermetallic ,Thermodynamics ,Laves phase ,Isothermal process ,Hydrogen storage ,Mechanics of Materials ,Phase (matter) ,Materials Chemistry ,Ternary operation ,Phase diagram - Abstract
The Ti–Fe–Mn alloys have attracted extensive interests due to the excellent hydrogen storage properties of the TiFe and TiMn2 (i.e. the C14 Laves phase) intermetallic compounds. The phase equilibria involving these two phases are essential for the design of hydrogen storage materials. In order to accelerate the design process, a thermodynamic description of the ternary Ti–Fe–Mn system was developed by experimental phase diagram study, ab initio calculations and CALPHAD-type thermodynamic modeling in the present work. The phase equilibria involving TiFe and C14 Laves phases were investigated by using electron probe microanalysis (EPMA). The partial isothermal sections at 1273 and 1373 K were established. Ab initio calculations were carried out to assist the determination of the thermodynamic parameters for the C14 Laves phase. The Ti-Mn system was re-assessed to reproduce the phase diagram data over the entire composition range. The Ti-Fe-Mn system was modeled and optimized based on reliable binary descriptions and experimental data. The TiFe and C14 Laves phases were well described to reproduce the phase equilibria with other phases in the ternary system. Moreover, the developed thermodynamic description of the Ti-Fe-Mn system was successfully applied for the prediction of phase constitutions of hydrogen storage alloys, demonstrating evidently the reliability of the practical use of present model parameters.
- Published
- 2022
29. Effect of fabrication parameters on the microstructure and mechanical properties of wire arc additive manufactured AZ61 alloy
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Pengfei Yan, Zhixian Zhao, Tao Ying, Jingya Wang, and Xiaoqin Zeng
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Materials science ,Fabrication ,Mechanical Engineering ,Alloy ,engineering.material ,Condensed Matter Physics ,Microstructure ,Grain size ,Arc (geometry) ,Mechanics of Materials ,engineering ,General Materials Science ,Current (fluid) ,Composite material ,Porosity ,Voltage - Abstract
The wire arc additive manufacturing (WAAM) was employed to fabricate the AZ61 alloys via different fabrication parameters. The microstructure, including grain size and porosity, varies with the processing conditions, which significantly influence the mechanical properties of the fabricated materials. The superior microstructure with fine grains and reduced porosity was achieved via fabrication parameters with current of 130A, voltage of 12.5 kV and wire feed speed of 820 mm/min, providing exceptionally excellent comprehensive mechanical properties.
- Published
- 2022
30. Obesity Without Metabolic Abnormality and Incident CKD: A Population-Based British Cohort Study
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Krishnarajah Niratharakumar, Abd A. Tahrani, Thomas Taverner, Krishna Gokhale, Indranil Dasgupta, G. Neil Thomas, and Jingya Wang
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education.field_of_study ,medicine.medical_specialty ,business.industry ,Population ,030232 urology & nephrology ,Overweight ,medicine.disease ,Obesity ,03 medical and health sciences ,0302 clinical medicine ,Nephrology ,Internal medicine ,Metabolically healthy obesity ,medicine ,030212 general & internal medicine ,medicine.symptom ,Underweight ,business ,education ,Body mass index ,Cohort study ,Kidney disease - Abstract
Rationale & Objective Metabolically healthy obesity (obesity without any metabolic abnormality) is not considered to be associated with increased risk of morbidity and mortality. We examined and quantified the association between metabolically healthy overweight/obesity and the risk of incident chronic kidney disease (CKD) in a British primary care population. Study Design Retrospective population-based cohort study. Setting & Participants 4,447,955 of the 5,182,908 adults in The Health Improvement Network (THIN) database (United Kingdom, 1995-2015) with a recorded body mass index (BMI) at the time of registration date who were free of CKD and cardiovascular disease. Exposure 11 body size phenotypes were created, defined by BMI categories (underweight, normal weight, overweight, and obesity) and 3 metabolic abnormalities (diabetes, hypertension, and dyslipidemia). Outcome Incident CKD defined as a recorded code for kidney replacement therapy, a recorded diagnosis of CKD, or by an estimated glomerular filtration rate of 3 mg/mmol for ≥90 days. Results Of the 4.5 million individuals, 1,040,921 (23.4%) and 588,909 (13.2%) had metabolically healthy overweight and metabolically healthy obesity, respectively. During a mean follow-up interval of 5.4 ± 4.3 (SD) years, compared with individuals with a metabolically healthy normal weight (n = 1,656,231), there was a higher risk of incident CKD among those who had metabolically healthy overweight (adjusted HR, 1.30 [95% CI, 1.28-1.33]) and metabolically healthy obesity (adjusted HR, 1.66 [95% CI, 1.62-1.70]). The association was stronger in those younger than 65 years of age. In all BMI categories, there was greater risk of incident CKD with a greater number of metabolic abnormalities in a graded manner. Limitations Potential misclassification of metabolic status due to delayed diagnosis and residual confounding due to unmeasured factors. Conclusions Overweight and obesity without metabolic abnormality are associated with a higher risk of incident CKD compared with those with normal body weight and no metabolic abnormality.
- Published
- 2022
31. Predictive Value of the Neutrophil-to-Lymphocyte Ratio(NLR) for Diagnosis and Worse Clinical Course of the COVID-19: Findings from Ten Provinces in China
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Jin Huang, Yipin Fan, Zhifei Wang, Lanping Wu, Yuanjun Li, Yanhua Xiao, Mingbo Yang, Wei Wang, Jinbo Zhang, Ruixia Xue, Minqing Li, Jinping Liu, Shoufang Xu, Shengli Yuan, Nannan Shi, Weiguo Bai, Sihong Liu, Haihao Jin, Junteng Zhu, Baihua Jiang, Liwen Jiao, Xiaofeng Zhang, Xiao Lei, Xiaomei Hu, Yanping Wang, Xiaoyan Wang, Renbo Chen, Liying Chen, Huamin Zhang, Yunhong Hu, Tianqing Zhu, Tuanmao Guo, Chen Zhao, Puye Yang, Guangxi Li, Yan Ma, Linsong Zhang, Hao Gu, Jingwei Wang, Fangli Song, Yinzhen Wang, Mei Shi, Ning Liang, Zhang Liu, Gongqi Zhang, Yingchun Zhou, Haijun Xie, Guifen Hu, Quntang Li, Dongting Wang, Jingya Wang, Hongming Xu, Shaozhen Huang, Hui Na, Ruili Huo, Yuanyuan Li, H. S. Chen, Zhan Shi, Kai Zheng, Nong Tang, Li Li, Wei Wu, Sheng Sun, Shusen Zhao, Huaben Zhang, Lin Tong, Huizhen Li, Jiangfeng Bai, Furong Xiao, Jia Liu, Qiao Feng, Yongyan Wang, Ya Mao, and Yingjie Zhi
- Subjects
medicine.medical_specialty ,Receiver operating characteristic ,business.industry ,Area under the curve ,Odds ratio ,medicine.disease ,Logistic regression ,Odds ,Internal medicine ,Viral pneumonia ,medicine ,Neutrophil to lymphocyte ratio ,business ,Cohort study - Abstract
Background: Novel coronavirus pneumonia (NCP) is often changing rapidly and fatal. Early detection and early triage of coronavirus disease 2019 (Covid-19) is the key to success management of the disease. An easily obtainable yet accurate variable for both diagnosis and prognosis is urgently needed. We aim to report predictive Value of the Neutrophil-to-Lymphocyte Ratio(NLR) for diagnosis and worse clinical course of the COVID-19, which have not been well demonstrated. Methods: Our study consisted of two stages, at the first stage, a retrospective, single-center, cohort study including was conducted in Heilongjiang, on admission, demographic, clinical, and laboratory data were collected and compared between patients with COVID-19 and patients with non COVID-19; we used multivariable logistic regression methods to explore the risk factors associated with COVID-19;A receiver operating characteristic(ROC) analysis was conducted to calculate the area under the curve(AUC) to assess predictive value of NLR for diagnosis of COVID 19. At the second stage, we conducted retrospective, multi-center and large sample study in 43 hospitals from ten provinces of China, COVID-19 patients with laboratory-confirmed divided into three groups including mild cases, ordinary cases and severe cases. Multivariate logistic regression methods were used to identify the risk factors for the deterioration of COVID-19, along with, a receiver operating characteristic (ROC) curve was also drawn to assess impact on the clinical course of the COVID-19. Findings: We recruited a total of 635 patients with COVID-19 and 27 cases with non COVID-19(Viral pneumonia) from 28 January to 25 February. A total of 88 cases were enrolled with a retrospective, single-center, cohort study from Heilongjiang province, of these, COVID-19 cases were 61(69%) and non COVID-19 cases were 27(31%). On admission, fever (69%) was the most common symptoms, cough (56%) and fatigue(53%). An average(SD) of NLR of COVID-19 patients and non- COVID-19 patients were3.48±2.04 and 2.21±1.14, respectively. multivariable regression showed increasing odds of COVID-19 patients associated with NLR(odds ratio 1.752, 95% CI 1.111-2.763, per 1 unit increase; p=0.016). In addition, the area under the curve (AUC) of NLR was 0.707 and cutoff value was 2.22. At the second stage, 635 patients with COVID were enrolled with a retrospective, multi-center, large sample study in the 43 settings from 10 provinces, of these, mild case were 86(14%), ordinary cases [486(76%)],severe cases[63(10%)], common symptoms was at onset of disease were cough[356(56%)], an average of NLR of 635 patients was 4.04±4.68, and elevated NLR with the deterioration of clinical course[mild case(2.73±2.28), ordinary cases(3.58±3.07), severe cases(9.38±10.52), P
- Published
- 2020
32. Assessment of atomic mobility for BCC Ti-Mn and Ti-Al-Mn alloys
- Author
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Hao Dong, Jingya Wang, Lian Zhou, Guanglong Xu, Yuwen Cui, National Natural Science Foundation of China, Jiangnan University, and China Scholarship Council
- Subjects
010302 applied physics ,Materials science ,General Chemical Engineering ,Ti-Al-Mn ,Atomic mobility ,Thermodynamics ,02 engineering and technology ,General Chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Ti-Mn ,Computer Science Applications ,Diffusion ,Condensed Matter::Materials Science ,CALPHAD ,0103 physical sciences ,Diffusion (business) ,0210 nano-technology ,Reliability (statistics) - Abstract
The atomic mobility in BCC Ti-Mn and Ti-Al-Mn alloys was assessed by using the DICTRA software after critically evaluating all available experimental diffusion data. Good agreements were obtained from the comprehensive comparisons between the calculated and experimental diffusion coefficients. The interdiffusion behaviour was further well predicted, confirming the reliability of the present mobility parameters., This work was supported by the Natural Science Funds of China [Grant No. 51571113], and the Joint Project of Industry-University-Research of Jiangsu Province [Grant No: BY2016005]. Ms. Jingya Wang acknowledges the financial support from the China Scholarship Council (Grant no. 201506890002).
- Published
- 2018
33. Enhanced catalysis of ultrasmall Au-MoS 2 clusters against reactive oxygen species for radiation protection
- Author
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Jingya Wang, Meixian Li, Haile Liu, Junying Wang, Peixian Bian, Yuan-Ming Sun, Jinxuan Zhang, Xiaodong Zhang, and Jiang Yang
- Subjects
chemistry.chemical_classification ,Reactive oxygen species ,Multidisciplinary ,Antioxidant ,Chemistry ,business.industry ,medicine.medical_treatment ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrocatalyst ,01 natural sciences ,0104 chemical sciences ,Nanomaterials ,Catalysis ,Ionizing radiation ,In vivo ,medicine ,Biophysics ,Radiation protection ,0210 nano-technology ,business - Abstract
Ionizing radiation produces excessive reactive oxygen species (ROS) which impose detrimental effects on biological systems. Thus, it is important to explore clinically safe and efficacious radioprotection agents to scavenge ROS and reduce the risks of radiotherapy. Recently, emerging catalytic nanomaterials such as sulfide nanomaterials have shown capability of clearing ROS in vivo by unique electron transfers between atoms, but their catalytic activities are yet suboptimal. As such, there is an unmet need to improve catalytic properties for stronger antioxidant activities and radiation protection. Herein, we prepared ultrasmall Au-MoS2 clusters (∼2.5 nm) and they showed enhanced catalytic properties via gold intercalation facilitating increased active sites and synergistic effects. Electrocatalysis results revealed that the catalytic activity of Au-MoS2 towards H2O2 was superior to ultrasmall MoS2 without Au. As a result, we found that improving the electrocatalytic property of Au-MoS2 can effectively enhance corresponding antioxidant activities and radioprotection effects in vivo. In addition, Au-MoS2 also showed significant radioprotection in vitro and dramatically reduced the excess of radiation-induced adverse ROS. It also rescued radiation-induced DNA damages and protected the bone marrow hematopoietic system from ionizing radiation.
- Published
- 2018
34. Experimental and computational study of diffusion mobilities for the bcc phase in the Fe-Al-(Si, Mn) systems
- Author
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Xiao-Gang Lu, Jingya Wang, Weisen Zheng, Yanlin He, and Lin Li
- Subjects
010302 applied physics ,Work (thermodynamics) ,Materials science ,General Chemical Engineering ,Alloy ,Thermodynamics ,02 engineering and technology ,General Chemistry ,engineering.material ,021001 nanoscience & nanotechnology ,01 natural sciences ,Computer Science Applications ,Phase (matter) ,0103 physical sciences ,engineering ,Diffusion (business) ,0210 nano-technology ,Electrical steel - Abstract
The electrical steel has attracted considerable attention due to the excellent soft magnetic properties, which can be improved by the addition of alloying elements such as Al, Si and Mn. To increase element contents, the hot-dipping and diffusion-annealing method has been developed. The method requires detailed insight on the diffusion behavior of the alloy system. In the present work, the re-assessment of the diffusion mobilities for the bcc phase (including both bcc_A2 and bcc_B2 phases) in the Fe-Al system were firstly performed based on the critical evaluation of the available experimental data. By applying the diffusion-couple method, the interdiffusion coefficients in bcc_A2 Fe-Al-Si alloys were determined and used to optimize the diffusion mobilities. The bcc_A2 Fe-Al-Mn diffusion couples were also designed to verify the diffusion mobilities. Comparison between the model-predicted and experimental diffusion data such as diffusion coefficients, concentration profiles and diffusion paths confirms the reliability of the present mobility parameters.
- Published
- 2018
35. Pr:Ca1-xRxF2+x (R=Y or Gd) crystals: Modulated blue, orange and red emission spectra with the proportion of R3+ ions
- Author
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Hao Yu, Xiaobo Qian, Fei Tang, Jingya Wang, Dapeng Jiang, Liangbi Su, Linyang Guo, Qinghui Wu, Qiangwen Ju, and Jun Xu
- Subjects
Materials science ,Absorption spectroscopy ,Organic Chemistry ,Analytical chemistry ,02 engineering and technology ,Orange (colour) ,021001 nanoscience & nanotechnology ,01 natural sciences ,Emission intensity ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials ,Ion ,010309 optics ,Inorganic Chemistry ,0103 physical sciences ,Quantum efficiency ,Emission spectrum ,Electrical and Electronic Engineering ,Physical and Theoretical Chemistry ,0210 nano-technology ,Luminescence ,Spectroscopy ,Blue light - Abstract
The spectroscopic properties of 0.6at.%:Pr:Ca1-xRxF2+x (R = Y, Gd; x = 0,0.006, 0.012, 0.03, 0.06) crystals were investigated and compared. The XRD tests were conducted and the cell dimensions of the crystals were calculated. Room temperature absorption spectra have been registered and analyzed. The emission spectra and decay curves of the crystals were obtained at room temperature. Increasing the proportion of the lattice regulators of Y3+ or Gd3+ ions could significantly enhance the luminescence intensity of all visible emission bands with different ratios. Particularly, the emission intensity ratio of orange to red increased from 0.15 to 1.9 in Pr:Ca1-xYxF2+x crystals and to 1.02 in Pr:Ca1-xGdxF2+x crystals, respectively. Furthermore, Pr:Ca1-xGdxF2+x crystals have substantially strong emission at orange and red region of 580–660 nm, comparable with blue light at 482 nm. The quantum efficiency of the crystals increased rapidly with the increment of R3+ concentration, and finally tend to be 100%.
- Published
- 2018
36. Person re-identification with activity prediction based on hierarchical spatial-temporal model
- Author
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Minxian Li, Chao Guan, Jinhui Tang, Fumin Shen, and Jingya Wang
- Subjects
Recall ,Computer science ,business.industry ,Cognitive Neuroscience ,020206 networking & telecommunications ,02 engineering and technology ,computer.software_genre ,Machine learning ,Re identification ,Computer Science Applications ,Range (mathematics) ,Artificial Intelligence ,Path (graph theory) ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,Artificial intelligence ,Data mining ,business ,Focus (optics) ,computer - Abstract
Person re-identification (re-id) across cameras remains a very challenging problem, especially when the wide range searching exists in a multi-camera surveillance network. Current person re-identification methods focus on using visual model to search the specified person. In fact, in practical applications, due to the large-scale search range, the searching way only relying on visual model is not efficient. Moreover, the recall ability of visual model usually is limited in large-scale searching, because it does not consider the spatial-temporal information of person. However, the current public re-id datasets only include the visual samples. To address this problem, in this work, we collect a large-scale re-id dataset, PKU-SVD-B-REID, which includes both visual and spatial-temporal information of over 133 K samples. Then, we propose a novel person re-id framework, named Hierarchical Spatial-Temporal Model (HSTM), which can effectively predict the person activity path and reduce the search range in the real multiple cameras surveillance system. Extensive experiments on PKU-SVD-B-REID validate the superiority of our method over conventional re-id methods based on only visual information in terms of both efficiency and accuracy.
- Published
- 2018
37. A multifactor model for predicting mortality in critically ill patients: A multicenter prospective cohort study
- Author
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Jian Zhang, Xu Liu, Zhijun Xu, Zhiyi Wang, Zhongqiu Lu, Guohao Xie, Man Huang, Baoli Cheng, Xiangming Fang, Zhongwang Li, Jingya Wang, Lihua Chu, Haiya Wu, Huaqin Sun, Jialian Zhao, and Xiaobo Yu
- Subjects
Male ,medicine.medical_specialty ,Neutrophils ,Critical Illness ,Critical Care and Intensive Care Medicine ,Logistic regression ,Leukocyte Count ,03 medical and health sciences ,0302 clinical medicine ,Predictive Value of Tests ,Intensive care ,Internal medicine ,Odds Ratio ,Humans ,Medicine ,Hospital Mortality ,Lactic Acid ,Lymphocytes ,Prospective Studies ,030212 general & internal medicine ,Prospective cohort study ,Intensive care medicine ,Aged ,Receiver operating characteristic ,business.industry ,Critically ill ,030208 emergency & critical care medicine ,Odds ratio ,Middle Aged ,Confidence interval ,Intensive Care Units ,ROC Curve ,Calibration ,Cohort ,Female ,business - Abstract
The objective of this study was to develop a model using a combination of routine clinical variables to predict mortality in critically ill patients.A cohort of 500 patients recruited from eight university hospital intensive care units (ICUs) was used to develop a model via logistic regression analyses. Discrimination and calibration analyses were performed to assess the model.The model included the lactate level (odds ratio [OR]=1.11, 95% confidence interval [CI] 1.01 to 1.22, P=0.029), neutrophil-to-lymphocyte ratio (OR=1.03, 95% CI 1.01 to 1.04, P=0.002), acute physiology score (OR=1.11, 95% CI 1.06 to 1.15, P0.001), Charlson comorbidity index (OR=1.36, 95% CI 1.15 to 1.60, P0.001) and surgery type (OR: selective=Ref, no surgery=8.04, 95% CI 3.74 to 17.30, P0.001, emergency=3.66, 95% CI 1.60 to 8.36, P=0.002). The model showed good discrimination (area under receiver operating characteristic curve: 0.84, 95% CI: 0.80 to 0.87) and calibration (Hosmer-Lemeshow test P=0.137) for predicting in-hospital mortality.The developed multifactor model can be used to effectively predict mortality in critically ill patients at ICU admission.
- Published
- 2017
38. A visual guide to gene/optothermal synergy therapy nanosystem using tungsten oxide
- Author
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Jingya Wang, Huizhuo Pan, Zhenyu Liao, Hanjie Wang, Xiaoqun Gong, Wanying Ji, Bin Zheng, Chen Hongbin, and Jin Chang
- Subjects
Fluorescence-lifetime imaging microscopy ,Materials science ,Genetic enhancement ,Nanoparticle ,Nanotechnology ,02 engineering and technology ,Photothermal therapy ,Mesoporous silica ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Fluorescence ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Biomaterials ,chemistry.chemical_compound ,Colloid and Surface Chemistry ,chemistry ,In vivo ,0210 nano-technology ,Indocyanine green - Abstract
Combination of gene therapy and photothermal therapy (PTT) has drawn much attention in cancer therapy in recent years. However, this joint treatment process lacks fluorescence imaging visualization guidance that limits its clinical applications in oncotherapy. Herein, we report the use of gene therapy and tungsten oxide (W18O49, WO) synthetized with template method for combined PTT of cancer. In this system, a novel nanoplatform, with Bax gene, WO and indocyanine green (ICG) loaded in mesoporous silica nanoparticle had been successfully constructed, which was used as the near-infrared imaging-guided gene/optothermal multi-modal oncotherapy. These nanoparticles could achieve a synergistic therapy effect of gene therapy and PTT for tumor under 808nm near-infrared (NIR) laser excitation. In vivo animal experiments showed that they could cause solid tumor regression under 808nm NIR light irradiation, revealing the potential of these nanocomposites as a fluorescence imaging-guided multi-modal therapeutic nanosystem for tumor visual synergistic treatment.
- Published
- 2017
39. Deformation mechanisms of Mg-Ca-Zn alloys studied by means of micropillar compression tests
- Author
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Yiwen Chen, Javier LLorca, Xiaoqin Zeng, Jingya Wang, and Zhe Chen
- Subjects
010302 applied physics ,Materials science ,Polymers and Plastics ,Metals and Alloys ,Nucleation ,02 engineering and technology ,Slip (materials science) ,021001 nanoscience & nanotechnology ,01 natural sciences ,Electronic, Optical and Magnetic Materials ,Deformation mechanism ,Critical resolved shear stress ,0103 physical sciences ,Ceramics and Composites ,Formability ,Texture (crystalline) ,Composite material ,0210 nano-technology ,Ductility ,Crystal twinning - Abstract
The effect of Ca and Zn in solid solution on the critical resolved shear stress (CRSS) of basal slip, tensile twinning and pyramidal slip in Mg alloys has been measured through compression tests on single crystal micropillars with different orientations. The solute atoms increased the CRSS for basal slip to ~ 13.5 MPa, while the CRSS for pyramidal slip was lower than 85 MPa, reducing significantly the plastic anisotropy in comparison with pure Mg. Moreover, the CRSSs for twin nucleation and growth were very similar (~ 37 MPa) and the large value of the CRSS for twin growth hindered the growth of twins during thermo-mechanical processing. Finally, evidence of prismatic slip and cross-slip between basal and prismatic dislocations was found. It is concluded that the reduction of plastic anisotropy, the activation of different slip systems and cross-slip and the weak basal texture promoted by the large CRSS for twin growth are responsible for the improved ductility and formability of Mg-Ca-Zn alloys.
- Published
- 2021
40. TGT growth and magneto-optical properties of PrF3 crystal
- Author
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Huifang Li, Liangbi Su, Jiayue Xu, Jiangtao Li, Guochao Jiang, Hui Shen, Jingya Wang, Zhonghan Zhang, and Anhua Wu
- Subjects
010302 applied physics ,Materials science ,Optical isolator ,Verdet constant ,business.industry ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Electronic, Optical and Magnetic Materials ,law.invention ,Magneto optical ,Crystal ,Temperature gradient ,law ,0103 physical sciences ,Optoelectronics ,Electrical and Electronic Engineering ,0210 nano-technology ,business ,Faraday rotator - Abstract
High quality PrF3 crystal was successfully grown by the temperature gradient technique (TGT). The magneto-optical properties of PrF3 crystal were systematically investigated in the UV-VIS-NIR region. The advantage of PrF3 over CeF3 and TGG is its transparency in deep-UV region down to 258 nm. The dispersions of Verdet constant of PrF3 and TGG crystals in VIS-NIR region are similar. The Verdet constant of PrF3 crystal can theoretically increase from 677.93 rad T−1•m−1 at 300 nm to 967.53 rad T−1•m−1 at 270 nm. The CeF3 and TGG crystals aren't transparent in this region. Therefore, PrF3 crystal is the promising candidate for use as a Faraday rotator for optical systems operating below 300 nm.
- Published
- 2021
41. Discovering visual concept structure with sparse and incomplete tags
- Author
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Jingya Wang, Xiatian Zhu, and Shaogang Gong
- Subjects
FOS: Computer and information sciences ,Structure (mathematical logic) ,Linguistics and Language ,Interpretation (logic) ,Information retrieval ,Exploit ,Computer science ,Computer Vision and Pattern Recognition (cs.CV) ,Computer Science - Computer Vision and Pattern Recognition ,02 engineering and technology ,010501 environmental sciences ,Semantics ,01 natural sciences ,TRECVID ,Language and Linguistics ,Task (project management) ,Random forest ,Artificial Intelligence ,0202 electrical engineering, electronic engineering, information engineering ,020201 artificial intelligence & image processing ,Cluster analysis ,0105 earth and related environmental sciences - Abstract
Discovering automatically the semantic structure of tagged visual data (e.g. web videos and images) is important for visual data analysis and interpretation, enabling the machine intelligence for effectively processing the fast-growing amount of multi-media data. However, this is non-trivial due to the need for jointly learning underlying correlations between heterogeneous visual and tag data. The task is made more challenging by inherently sparse and incomplete tags. In this work, we develop a method for modelling the inherent visual data concept structures based on a novel Hierarchical-Multi-Label Random Forest model capable of correlating structured visual and tag information so as to more accurately interpret the visual semantics, e.g. disclosing meaningful visual groups with similar high-level concepts, and recovering missing tags for individual visual data samples. Specifically, our model exploits hierarchically structured tags of different semantic abstractness and multiple tag statistical correlations in addition to modelling visual and tag interactions. As a result, our model is able to discover more accurate semantic correlation between textual tags and visual features, and finally providing favourable visual semantics interpretation even with highly sparse and incomplete tags. We demonstrate the advantages of our proposed approach in two fundamental applications, visual data clustering and missing tag completion, on benchmarking video (i.e. TRECVID MED 2011) and image (i.e. NUS-WIDE) datasets., Comment: Artificial Intelligence journal 2017
- Published
- 2017
42. Structure evolutions and high electrochemical performances of carbon aerogels prepared from the pyrolysis of phenolic resin gels containing ZnCl 2
- Author
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Rui Geng, Zijie Xu, Jingya Wang, Zhonghua Hu, and Lihua Gan
- Subjects
Materials science ,General Chemical Engineering ,Inorganic chemistry ,chemistry.chemical_element ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrochemistry ,01 natural sciences ,0104 chemical sciences ,Amorphous solid ,Dielectric spectroscopy ,symbols.namesake ,chemistry ,Specific surface area ,symbols ,Cyclic voltammetry ,0210 nano-technology ,Raman spectroscopy ,Carbon ,Pyrolysis - Abstract
Carbon aerogels (CAs) were prepared via the pyrolysis of phenolic resin gels (PRGs) containing ZnCl2. The pyrolysis of PRGs and the activation of resulted amorphous carbons in CAs can be carried out in one step. Structure characterizations of CAs were performed by X-ray diffraction, Raman spectrum and gas adsorption-desorption method. Electrochemical performances of CAs were investigated by cyclic voltammetry, galvanostatic charge-discharge and electrochemical impedance spectroscopy. CAs with specific surface area of 2846 m2 g−1 can display its specific capacitance of 246 F g−1 at 1 A g−1 and 219 F g−1 at 10 A g−1. The addition of ZnCl2 in matrix of PRGs by a hydrothermal treatment can effectively avoid its serious volatilization at higher temperatures and enhance its activation efficiency. A series of structure evolutions in CAs including their specific surface areas, pore volumes and accumulation states of laminar carbon molecules can be caused by changing the content of ZnCl2 in PRGs. High electrochemical performances of CAs are resulted from their adjusted carbon structures. The relation between the structure evolutions in CAs and their improved electrochemical performances is also discussed.
- Published
- 2017
43. Improved 2.79 μm continuous-wave laser performance from a diode-end pumped Er,Pr:CaF2 crystal
- Author
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Xiaodong Xu, Weiwei Ma, Jun Xu, Jingya Wang, Dapeng Jiang, Jie Liu, Lihe Zheng, Liangbi Su, Xiuwei Fan, and Jingjing Liu
- Subjects
Materials science ,business.industry ,Mechanical Engineering ,Slope efficiency ,Doping ,Metals and Alloys ,02 engineering and technology ,Cw laser ,021001 nanoscience & nanotechnology ,Laser ,01 natural sciences ,Fluorescence ,law.invention ,010309 optics ,Crystal ,Mechanics of Materials ,law ,0103 physical sciences ,Materials Chemistry ,Continuous wave ,Optoelectronics ,0210 nano-technology ,business ,Diode - Abstract
The spectral properties of lightly doped Er:CaF 2 and Er,Pr:CaF 2 single crystals were investigated. Benefited from particular clustering effect, 2.79 μm continuous-wave (CW) laser operation was demonstrated in lightly doped 3 at.% Er:CaF 2 crystal. After co-doping small amount of Pr 3+ , the lifetime gap between Er 3+ : 4 I 11/2 and Er 3+ : 4 I 13/2 was shortened from 7.86 ms to about 1 ms. Moreover, the near-infrared and up-conversion fluorescence were significantly quenched. Thus, the CW laser performance was greatly improved. The slope efficiency was effectively improved from 8.0% to 15.8%.
- Published
- 2017
44. A novel cross-linked enzyme aggregates (CLEAs) of papain and neutrase-production, partial characterization and application
- Author
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Yanwei Wang, Wei Liu, Haixia Chen, Jingya Wang, and Zhongqin Chen
- Subjects
0106 biological sciences ,Ammonium sulfate ,Hydrolyzed protein ,01 natural sciences ,Biochemistry ,Protein Aggregates ,chemistry.chemical_compound ,Structural Biology ,010608 biotechnology ,Enzyme Stability ,Papain ,Chemical Precipitation ,Thermal stability ,Molecular Biology ,Plant Proteins ,chemistry.chemical_classification ,Ethanol ,Chromatography ,010405 organic chemistry ,Hydrolysis ,Metalloendopeptidases ,General Medicine ,Enzymes, Immobilized ,Ph stability ,0104 chemical sciences ,Kinetics ,Cross-Linking Reagents ,Enzyme ,chemistry ,Glutaral ,Proteolysis ,Solvents ,Glutaraldehyde - Abstract
The neutrase (EC 3.4.24.4) and papain (EC 3.4.22.2) were together immobilized ascross-linked enzyme aggregates (N-P-CLEAs) and their properties were characterized. The influence of the precipitant, cross-linking ratio of glutaraldehyde and cross-linking time were investigated. Ethanol was selected as the more efficient precipitant compared with ammonium sulfate. The proper cross-linking ratio of enzyme and glutaraldehyde was 1:5 (v/v) and the optimized cross-linking time was 4h. N-P-CLEAs showed obvious improvement in thermal stability and pH stability than the free enzyme (P0.05) and could hold relatively high activity retention in nonpolar and hydrophilic solvents and without activity loss at 4°C for more than six months. The cross-linking reaction had been appeared in N-P-CLEAs and more orderly microscopic surface morphology of N-P-CLEAs was observed. The molecular weight and thermal denaturation temperature of N-P-CLEAs were increased while the isoelectric point was decreased compared with those of the free enzymes. Application of N-P-CLEAs in bean proteins and zein showed a higher degree of hydrolysis, such as the hydrolysis degree of mung bean protein hydrolyzed by N-P-CLEAs was 12%, increased by approximately 4.5% compared to that of free enzyme. The results demonstrated that the N-P-CLEAs was suitable for application in food protein hydrolysis.
- Published
- 2017
45. Characterization and storage properties of a new microencapsulation of tea polyphenols
- Author
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Jingya Wang, Wei Liu, Zhongqin Chen, Hongyi Li, and Haixia Chen
- Subjects
0106 biological sciences ,Antioxidant ,Chromatography ,Scanning electron microscope ,DPPH ,medicine.medical_treatment ,Phthalate ,Nanotechnology ,04 agricultural and veterinary sciences ,engineering.material ,040401 food science ,01 natural sciences ,law.invention ,chemistry.chemical_compound ,0404 agricultural biotechnology ,Magazine ,Coating ,chemistry ,law ,Polyphenol ,010608 biotechnology ,Spray drying ,medicine ,engineering ,Agronomy and Crop Science - Abstract
In order to improve the stability of tea polyphenols (TP), microencapsulation was applied by using spray drying method with hydroxypropyl methylcellulose phthalate as coating material. The obtained microcapsules were further characterized on the physical properties, encapsulation efficiency, in vitro digestion study, storage stability and antioxidant capacity. The antioxidant activity was evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. The microcapsules were found to have a smooth surface shape with a particle size distribution of 10–200 μm by scanning electron microscopy (SEM) observation. The encapsulation efficiency of microencapsulated TP was 70.98%. Release rate of TP from microcapsules in simulated intestinal fluid had increased significantly compared with that in simulated gastric fluid ( p p
- Published
- 2016
46. Predicting the Early Risk of Ophthalmopathy in Graves' Disease Patients Using TCR Repertoire
- Author
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Hui Guo, Bingyin Shi, Tingting Shi, Chengsheng Zhang, Jin-Kui Yang, Yufeng Liu, Kai Ye, Mingqian He, Xiaofei Yang, Jiadong Lin, Liping Wu, Xiaomei Liu, Yue Wang, and Jingya Wang
- Subjects
0301 basic medicine ,medicine.medical_specialty ,business.industry ,Graves' disease ,Medicine (miscellaneous) ,medicine.disease ,Tcr repertoire ,Letter to Editor ,Peripheral blood ,Graves' ophthalmopathy ,Eyelid swelling ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Clinical research ,Late diagnosis ,Informed consent ,030220 oncology & carcinogenesis ,Internal medicine ,medicine ,Molecular Medicine ,business ,Survival analysis - Abstract
Background: Graves' ophthalmopathy (GO), the common extrathyroidal manifestation in Graves' hyperthyroidism (GH), often has an unsatisfactory therapeutic effect due to late diagnosis. Methods: Firstly, we proposed a novel score termed TCR Clonal expansion and chaos Score (TCS) to characterize VJ. TCS score equals to the ratio between clonal expansion of TCR V-J combination and chaos of peptide similarity. Then, we sequenced the RNA transcripts from the complementarity determining region 3 (CDR3) of TCR Vβ from 100 peripheral blood samples, including 43 GO and 57 stable GH. Random forest method was applied to select candidate features with the best performance to classify GO and GH. Lastly, this model was applied in an independent validation dataset consisting of 18 stable GH samples and 17 GH samples who progressed to GO in the follow up visit. Findings: The leave-one-out cross validation showed this model with a sensitivity of 87.88% and a specificity of 81.08% to differentiate GO from stable GH. And it achieved a sensitivity and specificity of 70.59% and 72.22% for prediction GO progression in GH. Specifically, 12 of the 17 GH patients who were predicted as GO developed symptoms of eyelid swelling, chemosis or proptosis in a median of 6.5 months (4-9.75 months, IQR). In addition, GO-free survival analysis demonstrated that "predicted GO" patients (n = 17) were significant difference with "predicted GH" patients (n = 18) in GO progression (P = 0.015, log-rank test). Interpretation: Our finding provides a proof of concept for diagnosis and prognosis using TCR repertoire and may help develop novel prophylactic strategy for GO and other autoimmune diseases. Funding Statement: This work was supported by the National Key R&D Program of China (grant NO. 2018YFC1311500 (B.S.), 2017YFC0907500 (K.Y.) and 2018YFC0910400 (K.Y.)), National Science Foundation of China (NSFC) (grant NO. 81670725 (B.S.), 81500690 (Y.W.), 31671372 (K.Y.), 61702406 (X.Y.)), the Clinical Research Award of the First Affiliated Hospital of Xi'an Jiaotong University, China (grant NO. XJTU1AF-CRF-2017-001 (B.S.)), Natural Science Foundation of Shaanxi Province (2018JM70990 (Y.W.)), Key Research and Development Project of Shaanxi Province (grant NO. 2017ZDXM-SF-060 (B.S.)), the Fundamental Research Funds for the Central Universities (1191329875 (Y.W.)), China Postdoctoral Science Foundation (224646(Y.W.)). Declaration of Interests: The authors have declared that no conflict of interest exists. Ethics Approval Statement: This study was approved by the Ethic Committee of the First Affiliated Hospital of Xi’an Jiaotong University (KYLLSL-2015-004-01). Informed consent was sought from all patients before screening and study entry.
- Published
- 2019
47. Enhanced photoluminescence and initial red laser operation in Pr:CaF 2 crystal via co-doping Gd 3+ ions
- Author
-
Jun Xu, Fei Tang, Zhiping Cai, Bin Xu, Saiyu Luo, Liangbi Su, Dapeng Jiang, Jingya Wang, Xigun Yan, Qiangwen Ju, and Hao Yu
- Subjects
Materials science ,Photoluminescence ,Red laser ,business.industry ,Mechanical Engineering ,Doping ,Slope efficiency ,Analytical chemistry ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Ion ,010309 optics ,Crystal ,Mechanics of Materials ,0103 physical sciences ,Optoelectronics ,General Materials Science ,Emission spectrum ,0210 nano-technology ,business ,Intensity (heat transfer) - Abstract
The spectroscopic properties of the Pr-doped CaF2 crystals are investigated. The photoluminescence intensity in the visible region is drastically enhanced by co-doping Gd3+ ions in Pr:CaF2 crystal. Furthermore, relative emission intensities of the 484 nm, 598 nm and 642 nm emission lines are greatly improved. Continuous-wave laser oscillation of Pr, Gd:CaF2 crystal at ∼642 nm is realized at room temperature, for the first time to our knowledge. The highest output power of 22.2 mW is achieved with a slope efficiency of 7.5%.
- Published
- 2017
48. Effects of Er3+ concentration on upconversion luminescence and temperature sensing properties in Bi4Ge3O12 crystal
- Author
-
Liangbi Su, Bo Zhang, Jingya Wang, Qiuhong Yang, Binghui Huang, and Xiaobo Qian
- Subjects
Diffraction ,Materials science ,Mechanical Engineering ,Doping ,Metals and Alloys ,Analytical chemistry ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Laser ,01 natural sciences ,Photon upconversion ,0104 chemical sciences ,Ion ,law.invention ,Crystal ,Mechanics of Materials ,law ,Excited state ,Materials Chemistry ,0210 nano-technology ,Luminescence - Abstract
Er3+ doped Bi4Ge3O12(BGO) crystals with different Er3+ ion concentration were prepared by Bridgman-Stockbarge (B–S) method and the temperature dependence of its upconversion (UC) luminescence was investigated systematically. The phases and luminescence properties of all the samples were characterized by X-ray diffraction (XRD) and upconversion luminescence (UCL) spectra. The temperature sensing performance of Er3+ doped Bi4Ge3O12 sample was studied via the fluorescence intensity ratio method from two thermally coupled 2H11/2 and 4S3/2 levels. Excited by 980 nm laser, the sensitivity first increased and then decreased with the increase of Er3+ ion concentration, and the maximum sensitivity can be obtained in the 0.3 mol% Er3+ doped sample at 498 K for 50.3 × 10−4 K−1. Meanwhile, the experiment also proved that Er3+ doped BGO as temperature sensing has a high reliability and repeatability. The influence mechanism of concentration on temperature sensing was studied by using the calculation of the Judd-Ofelt (J-O) theory, 0.3 mol% Er3+ doped Bi4Ge3O12 sample had a larger the ratio of the green radiation transition rate at the thermal coupling level. These results indicated that Er3+ doped Bi4Ge3O12(BGO) crystals may be a good candidate material as optical temperature sensor.
- Published
- 2021
49. Association between early treatment with Qingfei Paidu decoction and favorable clinical outcomes in patients with COVID-19: A retrospective multicenter cohort study
- Author
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Zhan Shi, Jin Huang, Jia Liu, Nannan Shi, Xiaohui Zhang, Liying Chen, Ning Liang, Yong Hou, Kaijun Yang, Kai Zheng, Yang Zhao, Yingchun Zhou, Lin Tong, Heng Gu, Liufen Mo, Gongqi Zhang, Xiaomei Hu, Fangli Song, Jinbo Zhang, Hongming Xu, Hui Na, Qiao Feng, H. S. Chen, Honggang Yi, Yongyan Wang, Youwen Ge, Yan Ma, Chun Yang, Liang Ji, Shusen Zhao, Zhang Liu, Chunyan Li, Yunhong Hu, Wanying Zhao, Huamin Zhang, Ya Mao, Yinzhen Wang, Li Li, Wei Wu, Renbo Chen, Hao Gu, Yipin Fan, Yingjie Zhi, Mingxuan Wang, Xiao Lei, Shengli Yuan, Shoufang Xu, Liwen Jiao, Lanping Wu, Yanhua Xiao, Wei Wang, Junteng Zhu, Haihao Jin, Minqing Li, Guifen Hu, Yibai Xiong, Shaowen Tang, Yuting Ma, Guihui Wu, Qiuhua Huang, Haijun Xie, Xiaoyan Wang, Sheng Sun, Quntang Li, Yaxin Tian, Ruixia Xue, Yanping Wang, Jinping Liu, Jike Li, Bin Liu, Hongde Liu, Jiangfeng Bai, Shaozhen Huang, Yuan Kuang, Puye Yang, Xianyong Li, Linsong Zhang, Guangxi Li, Tuanmao Guo, Chen Zhao, Jingwei Wang, Huizhen Li, Yuanyuan Li, Dongting Wang, Ruili Huo, Zhifei Wang, Tianqing Zhu, Hongmei Wo, Weiguo Bai, Sihong Liu, Jingya Wang, and Yudong Wang
- Subjects
Male ,0301 basic medicine ,RT-PCR, reverse transcription-polymerase-chain-reaction ,Decoction ,Disease ,Cohort Studies ,0302 clinical medicine ,Early treatment ,Prospective cohort study ,COVID-19, coronavirus disease 2019 ,Aged, 80 and over ,Hazard ratio ,RBC, red blood cell ,Middle Aged ,CT, computed tomography ,Treatment Outcome ,030220 oncology & carcinogenesis ,CRP, C-reactive protein ,Female ,Qingfei Paidu decoction ,WBC, white blood cell ,Cohort study ,Unadj., unadjusted ,Adult ,SARS-COV-2, severe acute respiratory syndrome-coronavirus 2 ,China ,medicine.medical_specialty ,Ref., reference ,Article ,Time-to-Treatment ,Young Adult ,03 medical and health sciences ,Internal medicine ,medicine ,Humans ,IFN, interferon ,QFPDD, Qingfei Paidu Decoction ,Viral shedding ,Adj., adjusted ,PO2, partial pressure of oxygen ,ComputingMethodologies_COMPUTERGRAPHICS ,Aged ,ESR, erythrocyte sedimentation rate ,Pharmacology ,business.industry ,COVID-19 ,Length of Stay ,No., number of patients ,HR, hazard ratio ,Confidence interval ,COVID-19 Drug Treatment ,CI, confidence interval ,030104 developmental biology ,COPD, chronic obstructive pulmonary disease ,SpO2, blood oxygen saturation ,Sample size determination ,WISP, work information system platform ,business ,Drugs, Chinese Herbal ,Follow-Up Studies - Abstract
Graphical abstract, The coronavirus disease 2019 (COVID-19) epidemic has been almost controlled in China under a series of policies, including “early diagnosis and early treatment”. This study aimed to explore the association between early treatment with Qingfei Paidu decoction (QFPDD) and favorable clinical outcomes. In this retrospective multicenter study, we included 782 patients (males, 56 %; median age 46) with confirmed COVID-19 from 54 hospitals in nine provinces of China, who were divided into four groups according to the treatment initiation time from the first date of onset of symptoms to the date of starting treatment with QFPDD. The primary outcome was time to recovery; days of viral shedding, duration of hospital stay, and course of the disease were also analyzed. Compared with treatment initiated after 3 weeks, early treatment with QFPDD after less than 1 week, 1-2 weeks, or 2-3 weeks had a higher likelihood of recovery, with adjusted hazard ratio (HR) (95 % confidence interval [CI]) of 3.81 (2.65–5.48), 2.63 (1.86-3.73), and 1.92 (1.34-2.75), respectively. The median course of the disease decreased from 34 days to 24 days, 21 days, and 18 days when treatment was administered early by a week (P < 0.0001). Treatment within a week was related to a decrease by 1-4 days in the median duration of hospital stay compared with late treatment (P
- Published
- 2020
50. PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity
- Author
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Bo Zhou, Yali Dou, Jie Xiong, Natarajan V. Bhanu, Rajesh C. Rao, Benjamin A. Garcia, Jay L. Hess, Qi Guo, Jingya Wang, Yuqing Sun, Shirley Y. Lee, and Peilin Ma
- Subjects
0301 basic medicine ,PRDM16 ,Methyltransferase ,Histone methyltransferase activity ,Cell Biology ,Biology ,Chromatin ,03 medical and health sciences ,030104 developmental biology ,Transcription (biology) ,DNA methylation ,Cancer research ,Gene silencing ,Molecular Biology ,Transcription factor - Abstract
PRDM16 is a transcription co-factor that plays critical roles in development of brown adipose tissue, as well as maintenance of adult hematopoietic and neural stem cells. Here we report that PRDM16 is a histone H3K4 methyltransferase on chromatin. Mutation in the N-terminal PR domain of PRDM16 abolishes the intrinsic enzymatic activity of PRDM16. We show that the methyltransferase activity of PRDM16 is required for specific suppression of MLL fusion protein-induced leukemogenesis both in vitro and in vivo. Mechanistic studies show that PRDM16 directly activates the SNAG family transcription factor Gfi1b, which in turn downregulates the HOXA gene cluster. Knockdown Gfi1b represses PRDM16-mediated tumor suppression, while Gfi1b overexpression mimics PRDM16 overexpression. In further support of the tumor suppressor function of PRDM16, silencing PRDM16 by DNA methylation is concomitant with MLL-AF9-induced leukemic transformation. Taken together, our study reveals a previously uncharacterized function of PRDM16 that depends on its PR domain activity.
- Published
- 2016
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