Search

Your search keyword '"Kris Naudts"' showing total 4 results
Start Over Author "Kris Naudts" Publisher elsevier bv
4 results on '"Kris Naudts"'

1. Deletion variant of α2b-adrenergic receptor gene moderates the effect of COMT val158met polymorphism on episodic memory performance

Author

Anthony S. David, Ayana A. Gibbs, Kris Naudts, and Ruben T. Azevedo

Subjects
Adult, Male, Adolescent, Genotype, Adrenergic receptor, Catechol O-Methyltransferase, behavioral disciplines and activities, Receptors, Adrenergic, alpha-2, mental disorders, Humans, Memory impairment, Pharmacology (medical), Prefrontal cortex, Receptor, Gene, Episodic memory, Biological Psychiatry, Pharmacology, Genetics, Polymorphism, Genetic, Catechol-O-methyl transferase, fungi, Psychiatry and Mental health, Neurology, Mental Recall, Neurology (clinical), Psychology, Neuroscience, Gene Deletion
Abstract

The COMT val(158) variant has been associated with impaired cognitive function compared to the Met(158) variant yet gene gene interactions are not well described. In this study we demonstrate an interaction between this COMT polymorphism and a deletion variant of ADRA2B, the gene encoding the alpha 2b-adrenergic receptor on episodic memory performance. Specifically, carriage of the ADRA2B deletion abolished the relative memory impairment in homozygous COMT val(158) carriers compared to Met(158) carriers.

Published
2010

Catalog

Books, media, physical & digital resources
See catalog results