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2. Multi-institutional Analysis of Metastasis-directed Therapy with or Without Androgen Deprivation Therapy in Oligometastatic Castration-sensitive Prostate Cancer

Author

Deek, Matthew P., primary, Sutera, Philip, additional, Jing, Yuezhou, additional, Gao, Robert, additional, Rothman, Emily, additional, Day, Heather, additional, Chang, David, additional, Dirix, Piet, additional, Armstrong, Andrew J., additional, Campbell, Bethany, additional, Campos, Fernando Lopez, additional, Berenguer, Miguel, additional, Ramotar, Matthew, additional, Conde-Moreno, Antonio, additional, Berlin, Alejandro, additional, Bosetti, Davide Giovanni, additional, Corcoran, Niall, additional, Koontz, Bridget, additional, Mercier, Carole, additional, Siva, Shankar, additional, Pryor, David, additional, Ost, Piet, additional, Huynh, Mai Anh, additional, Kroeze, Stephanie, additional, Stish, Bradley, additional, Kiess, Ana, additional, Trock, Bruce, additional, Tran, Phuoc T., additional, Gillessen, Silke, additional, and Sweeney, Christopher, additional

Published
2024
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6. Setting goals for agricultural nitrogen emission reduction to ensure safe air and groundwater quality: A case study of Quzhou, the North China Plain

Author

Meng, Fanlei, primary, Ronda, Reinder, additional, Strokal, Maryna, additional, Kroeze, Carolien, additional, Ma, Lin, additional, Krol, Maarten, additional, de Graaf, Inge, additional, Zhao, Yuanhong, additional, Wang, Yutong, additional, Du, Xiaohui, additional, Liu, Xuejun, additional, Xu, Wen, additional, Zhang, Fusuo, additional, and Wang, Mengru, additional

Published
2024
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7. Driving Factors of Recommending a Hand Surgery Clinic After Surgery

Author

Porsius, Jarry T., primary, ter Stege, Marloes H.P., additional, Selles, Ruud W., additional, Slijper, Harm P., additional, Blomme, R.A.M., additional, Sluijter, B.J.R., additional, van der Avoort, D.J.J.C., additional, Halbesma, G.J., additional, Kroeze, A., additional, Smit, J., additional, Debeij, J., additional, Walbeehm, E.T., additional, van Couwelaar, G.M., additional, Vermeulen, G.M., additional, de Schipper, J.P., additional, Temming, J.F.M., additional, van Uchelen, J.H., additional, de Boer, H.L., additional, de Haas, K.P., additional, Harmsen, K., additional, Zöphel, O.T., additional, Feitz, R., additional, Souer, J.S., additional, Koch, R., additional, Hovius, S.E.R., additional, Moojen, T.M., additional, Smit, X., additional, Hagen, R., additional, van Huis, R., additional, Pennehouat, P.Y., additional, Schoneveld, K., additional, van Kooij, Y.E., additional, Wouters, R.M., additional, Veltkamp, J., additional, Fink, A., additional, Esteban Lopez, L., additional, de Ridder, W.A., additional, Slijper, H.P., additional, Selles, R.W., additional, Porsius, J.T., additional, Tsehaie, J., additional, Poelstra, R., additional, Jansen, M.C., additional, van der Oest, M.J.W., additional, Hoogendam, L., additional, Teunissen, J.S., additional, Koopman, J.E., additional, Dekker, J., additional, ter Stege, M.H.P., additional, Zuidam, J.M., additional, Hundepool, C.A., additional, van der Heijden, B.E.P.A., additional, Colaris, J.W., additional, and Bijlsma, W.R., additional

Published
2023
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9. OA06.03 An International EORTC Survey on Resectability of Stage III Non-small Cell Lung Cancer

Author

Houda, I., primary, Bahce, I., additional, Dickhoff, C., additional, Kroese, T.E., additional, Kroeze, S.G.C., additional, Mariolo, A.V., additional, Tagliamento, M., additional, Moliner, L., additional, Brandao, M., additional, Edwards, J., additional, Opitz, I., additional, Faivre-Finn, C., additional, de Ruysscher, D., additional, Remon, J., additional, Berghmans, T., additional, Dingemans, A.-M.C., additional, Besse, B., additional, and Hendriks, L.E.L., additional

Published
2023
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12. Multi-Institutional Analysis of Metastasis Directed Therapy with or without Androgen Deprivation Therapy in Oligometastatic Castration Sensitive Prostate Cancer

Author

Sutera, P., primary, Deek, M.P., additional, Jing, Y., additional, Pryor, D.I., additional, Huynh, M.A., additional, Koontz, B.F., additional, Mercier, C., additional, Ost, P., additional, Kiess, A.P., additional, Conde-Moreno, A.J., additional, Stish, B.J., additional, Bosetti, D.G., additional, Siva, S., additional, Berlin, A., additional, Kroeze, S., additional, Corcoran, N., additional, Trock, B., additional, Gillessen, S., additional, Tran, P.T., additional, and Sweeney, C., additional

Published
2023
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13. EuroClonality-NGS Recommendations for Evaluation of B-Cell Clonality Analysis by Next-Generation Sequencing

Author

van den Brand, Michiel, primary, Möbs, Markus, additional, Otto, Franziska, additional, Kroeze, Leonie I., additional, Gonzalez de Castro, David, additional, Stamatopoulos, Kostas, additional, Davi, Frederic, additional, Bravetti, Clotilde, additional, Kolijn, P. Martijn, additional, Vlachonikola, Elisavet, additional, Stewart, J. Peter, additional, Pott, Christiane, additional, Hummel, Michael, additional, Darzentas, Nikos, additional, Langerak, Anton W., additional, Fend, Falko, additional, and Groenen, Patricia J.T.A., additional

Published
2023
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14. Patient-Reported Outcomes and Function After Surgical Repair of the Ulnar Collateral Ligament of the Thumb

Author

Legerstee, Ingmar W.F., primary, van der Oest, Mark J.W., additional, Souer, J. Sebastiaan, additional, Hundepool, Caroline A., additional, Duraku, Liron S., additional, Selles, Ruud W., additional, Zuidam, J. Michiel, additional, Blomme, R.A.M., additional, Sluijter, B.J.R., additional, van der Avoort, D.J.J.C., additional, Halbesma, G.J., additional, Kroeze, A., additional, Smit, J., additional, Debeij, J., additional, Walbeehm, E.T., additional, van Couwelaar, G.M., additional, Vermeulen, G.M., additional, de Schipper, J.P., additional, Temming, J.F.M., additional, van Uchelen, J.H., additional, de Boer, H.L., additional, de Haas, K.P., additional, Harmsen, K., additional, Zöphel, O.T., additional, Feitz, R., additional, Koch, R., additional, Hovius, S.E.R., additional, Moojen, T.M., additional, Smit, X., additional, Hagen, R., additional, van Huis, R., additional, Pennehouat, P.Y., additional, Schoneveld, K., additional, van Kooij, Y.E., additional, Wouters, R.M., additional, Veltkamp, J., additional, Fink, A., additional, Esteban Lopez, L., additional, de Ridder, W.A., additional, Slijper, H.P., additional, Porsius, J.T., additional, Tsehaie, J., additional, Poelstra, R., additional, Jansen, M.C., additional, Hoogendam, L., additional, Teunissen, J.S., additional, Koopman, J.E., additional, Dekker, J., additional, ter Stege, M.H.P., additional, van Nieuwenhoven, C.A., additional, van der Heijden, B.E.P.A., additional, Colaris, J.W., additional, and Bijlsma, W.R., additional

Published
2023
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15. Prevalence and Risk Factors for Postoperative Complications Following Open A1 Pulley Release for a Trigger Finger or Thumb

Author

Jaimy E. Koopman, Bo E. Zweedijk, Caroline A. Hundepool, Liron S. Duraku, Jeroen Smit, Robbert M. Wouters, Ruud W. Selles, J. Michiel Zuidam, D.J.J.C. van der Avoort, R.A.M. Blomme, H.L. de Boer, G.M. van Couwelaar, J. Debeij, J. Dekker, F.J. van Ewijk, R. Feitz, A. Fink, K.P. de Haas, K. Harmsen, L. Hoogendam, S.E.R. Hovius, R. van Huis, M.L. Jansen-Landheer, R. Koch, Y.E. van Kooij, A. Kroeze, T.M. Moojen, M.J.W. van der Oest, P.Y. Pennehouat, W.A. de Ridder, J.P. de Schipper, K. Schoneveld, H.P. Slijper, B.J.R. Sluijter, X. Smit, J.S. Souer, M. ter Stege, J.F.M. Temming, J.S. Teunissen, J.H. van Uchelen, J.J. Veltkamp, G.M. Vermeulen, E.T. Walbeehm, O.T. Zöphel, Plastic and Reconstructive Surgery and Hand Surgery, and Rehabilitation Medicine

Subjects
Postoperative Complications, Thumb, Trigger Finger Disorder, Risk Factors, Prevalence, Humans, Steroids, Orthopedics and Sports Medicine, Surgery, Retrospective Studies
Abstract

Purpose: Although A1 pulley release is an effective treatment to reduce pain and improve hand function, complications may occur. More insight into risk factors for complications is essential to improve patient counseling and potentially target modifiable risk factors. This study aimed to identify factors associated with complications following A1 pulley release. Methods: Patients completed baseline questionnaires, including patient characteristics, clinical characteristics, and the Michigan Hand outcomes Questionnaire. We retrospectively reviewed medical records to identify complications classified using the International Consortium for Health Outcome Measurement Complications in Hand and Wrist conditions tool. Grade 1 complications comprise treatment with additional hand therapy, splinting, or analgesics, grade 2 treatment with antibiotics or steroid injections, grade 3A minor surgical treatment, grade 3B major surgical treatment, and grade 3C complex regional pain syndrome. Logistic regression analyses were performed to examine the contribution of patient characteristics, clinical characteristics, and patient-reported outcome measurement scores to complications. Results: Of the included 3,428 patients, 16% incurred a complication. The majority comprised milder grades 1 (6%) and 2 (7%) complications, followed by more severe grades 3B (2%), 3C (0.1%), and 3A (0.1%) complications. A longer symptom duration (standardized odds ratio [SOR], 1.09), ≥3 preoperative steroid injections (SOR, 3.22), a steroid injection within 3 months before surgery (SOR, 2.02), and treatment of the dominant hand (SOR, 1.34), index finger (SOR, 1.65), and middle finger (SOR, 2.01) were associated with a higher complication rate. Conclusion: This study demonstrates that ≥3 preoperative steroid injections and a steroid injection within 3 months before surgery were the most influential factors contributing to complications. These findings can assist clinicians during patient counseling and may guide preoperative treatment. We recommend that clinicians should consider avoiding steroid injections within 3 months before surgery and to be reluctant to perform >2 steroid injections. Type of study/level of evidence: Prognostic II.

Published
2022
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17. Salvage radiotherapy is effective in patients with PSMA-PET-negative biochemical recurrence- results of a retrospective study

Author

Scharl, Sophia, primary, Zamboglou, Constantinos, additional, Strouthos, Iosif, additional, Farolfi, Andrea, additional, Serani, Francesca, additional, Lanzafame, Helena, additional, Giuseppe Morganti, Alessio, additional, Trapp, Christian, additional, Koerber, Stefan A., additional, Debus, Jürgen, additional, Peeken, Jan C., additional, Vogel, Marco M.E., additional, Vrachimis, Alexis, additional, Spohn, Simon K.B., additional, Ruf, Juri, additional, Grosu, Anca-Ligia, additional, Ceci, Francesco, additional, Fendler, Wolfgang P., additional, Bartenstein, Peter, additional, Kroeze, Stephanie G.C., additional, Guckenberger, Matthias, additional, Krafcsik, Manuel, additional, Klopscheck, Christina, additional, Fanti, Stefano, additional, Hruby, George, additional, Emmett, Louise, additional, Belka, Claus, additional, Stief, Christian, additional, Schmidt-Hegemann, Nina-Sophie, additional, Henkenberens, Christoph, additional, Mayer, Benjamin, additional, Miksch, Jonathan, additional, Shelan, Mohamed, additional, Aebersold, Daniel M., additional, Thamm, Reinhard, additional, and Wiegel, Thomas, additional

Published
2023
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20. OC-0435 Multi-institutional nomogram for PSMA-PET based salvage radiotherapy in recurrent prostate cancer

Author

Zamboglou, C., primary, Ferentinos, K., additional, Arnoux, A., additional, Janbain, A., additional, Strouthose, I., additional, Farolfi, A., additional, Koerber, S., additional, Peeken, J., additional, Vogel, M., additional, Vrachimis, A., additional, Spohn, S.K.B., additional, Shelan, M., additional, Grosu, A., additional, Kroeze, S., additional, Guckenberger, M., additional, Fanti, S.F., additional, Belka, C., additional, Hruby, G., additional, Scharl, S., additional, Wiegel, T., additional, Henkenberens, C., additional, Emmett, L., additional, and Schmidt-Hegemann, N.S., additional

Published
2023
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21. OC-0270 Metastases-directed SRT and systemic therapy: EORTC-ESTRO OligoCare delphi consensus recommendations

Author

Kroeze, S., primary, Pavic, M., additional, Stellamans, K., additional, Lievens, Y., additional, Becherini, C., additional, Scorsetti, M., additional, Alongi, F., additional, Ricardi, U., additional, Jereczek, B., additional, Westhoff, P., additional, But-Hadzic, J., additional, Widder, J., additional, Geets, X., additional, Bral, S., additional, Lambrecht, M., additional, Billiet, C., additional, Sirak, I., additional, Ramella, S., additional, Battista, I.G., additional, Benavente, S., additional, Zapatero, A., additional, Romero, F., additional, Zilli, T., additional, Khanfir, K., additional, Hemmatazad, H., additional, De Bari, B., additional, Klass, D., additional, Adnan, S., additional, Peulen, H., additional, Salinas Ramos, J., additional, Strijbos, M., additional, Popat, S., additional, Ost, P., additional, and Guckenberger, M., additional

Published
2023
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22. Multiple Compression Syndromes of the Same Upper Extremity: Prevalence, Risk Factors, and Treatment Outcomes of Concomitant Treatment

Author

Mendelaar, Nienke H.A., primary, Hundepool, Caroline A., additional, Hoogendam, Lisa, additional, Duraku, Liron S., additional, Zöphel, Oliver T., additional, Selles, Ruud W., additional, Zuidam, J. Michiel, additional, Blomme, Richard Arjen Michiel, additional, van der Avoort, Dirk-Jan, additional, Halbesma, Gert-Jan, additional, Kroeze, Alexander, additional, Smit, Jeronimus (Jeroen) Maria, additional, Debeij, Jan, additional, Walbeehm, Erik Taco, additional, van Couwelaar, Gijs Marijn, additional, Vermeulen, Guus Maarten, additional, de Schipper, Johannes (Hans) Pieter, additional, Temming, Johannes (Hans) Frederikes Maria, additional, van Uchelen, Jeroen Hein, additional, de Boer, Herman Luitzen, additional, de Haas, Nicoline, additional, Harmsen, Kennard, additional, Zöphel, Oliver Theodor, additional, Feitz, Reinier, additional, Souer, John Sebastiaan, additional, Koch, Richard, additional, Hovius, Steven Eric Ruden, additional, Moojen, Thybout Matthias, additional, Smit, Xander, additional, van Huis, Rob, additional, Pennehouat, Pierre-Yves Alain Adriaan, additional, Schoneveld, Karin, additional, van Kooij, Yara Eline, additional, Wouters, Robbert Maarten, additional, Fink, Alexandra, additional, Lopez, Lisa Esteban, additional, de Ridder, Willemijn Anna, additional, Slijper, Harm Pieter, additional, Selles, Ruud Willem, additional, Tsehaie, Jonathan, additional, Poelstra, Ralph, additional, van der Oest, Mark Johannes Willem, additional, Teunissen, Joris Sebastiaan, additional, Koopman, Jaimy Emerentiana, additional, Loos, Nina Louisa, additional, ter Stege, Marloes Hendrina Paulina, additional, Zuidam, Jelle Michiel, additional, van Nieuwenhoven, Christianne, additional, Hundepool, Caroline Anna, additional, van der Heijden, Brigitte, additional, Colaris, Joost, additional, and Bijlsma, Ward Rogier, additional

Published
2023
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23. PD-0064 Metastases-directed SRT combined with systemic therapy: 2y results of the TOaSTT real-world database

Author

Kroeze, S., primary, Schaule, J., additional, Spaas, M., additional, Kahl, K.H., additional, Verhoeff, J.J., additional, Schneiders, F.L., additional, Blanck, O., additional, Lohaus, F., additional, Rogers, S., additional, Kaul, D., additional, Benavente, S., additional, Combs, S.E., additional, Skazikis, G., additional, Baumann, K., additional, Popp, I., additional, Koppe, F., additional, Geinitz, H., additional, de Jaeger, K.E., additional, Siva, S., additional, Stera, S., additional, Wittig-Sauerwein, A., additional, Lewitzki, V., additional, Eckert, F., additional, Schymalla, M.M., additional, and Guckenberger, M., additional

Published
2023
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24. Definition and Diagnosis of Oligometastatic Bladder Cancer: A Delphi Consensus Study Endorsed by the European Association of Urology, European Society for Radiotherapy and Oncology, and European Society of Medical Oncology Genitourinary Faculty

Author

Bamias, Aristotelis, primary, Stenzl, Arnulf, additional, Brown, Stephanie L., additional, Albiges, Laurence, additional, Babjuk, Marko, additional, Birtle, Alison, additional, Briganti, Alberto, additional, Burger, Maximilian, additional, Choudhury, Ananya, additional, Colecchia, Maurizio, additional, De Santis, Maria, additional, Fanti, Stefano, additional, Fonteyne, Valérie, additional, Gallucci, Michele, additional, Rivas, Juan Gómez, additional, Huddart, Robert, additional, Junker, Kerstin, additional, Kroeze, Stephanie, additional, Loriot, Yohann, additional, Merseburger, Axel, additional, Montironi, Rodolfo, additional, Necchi, Andrea, additional, Oing, Christoph, additional, Oldenburg, Jan, additional, Ost, Piet, additional, Pinkawa, Michael, additional, Ribal, Maria J., additional, Rouprêt, Morgan, additional, Thoeny, Harriet, additional, Zilli, Thomas, additional, and Hoskin, Peter, additional

Published
2023
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25. Detection of Second Primary Lymphoma in Late Diffuse Large B-cell Lymphoma Recurrences

Author

Berendsen, Madeleine R., primary, Bladel, Diede A.G. van, additional, Hesius, Eva, additional, de Groot, Fleur A., additional, Kroeze, Leonie I., additional, Rijntjes, Jos, additional, Luijks, Jeroen A.C.W., additional, Hoevenaars, Brigiet, additional, Halilovic, Altuna, additional, Nooijen, Peet, additional, Bladel, Esther van, additional, Jonge-Peeters, Susan de, additional, Lensen, Chantal, additional, Pruijt, Hans, additional, van der Spek, Ellen, additional, Vermaat, Joost S.P., additional, Hess, Corine, additional, Hebeda, Konnie M., additional, Stevens, Wendy B.C., additional, van Krieken, J. Han J.M., additional, van den Brand, Michiel, additional, Groenen, Patricia J.T.A., additional, and Scheijen, Blanca, additional

Published
2023
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26. Definition and Diagnosis of Oligometastatic Bladder Cancer: A Delphi Consensus Study Endorsed by the European Association of Urology, European Society for Radiotherapy and Oncology, and European Society of Medical Oncology Genitourinary Faculty

Author

Aristotelis Bamias, Arnulf Stenzl, Stephanie L. Brown, Laurence Albiges, Marko Babjuk, Alison Birtle, Alberto Briganti, Maximilian Burger, Ananya Choudhury, Maurizio Colecchia, Maria De Santis, Stefano Fanti, Valérie Fonteyne, Michele Gallucci, Juan Gómez Rivas, Robert Huddart, Kerstin Junker, Stephanie Kroeze, Yohann Loriot, Axel Merseburger, Rodolfo Montironi, Andrea Necchi, Christoph Oing, Jan Oldenburg, Piet Ost, Michael Pinkawa, Maria J. Ribal, Morgan Rouprêt, Harriet Thoeny, Thomas Zilli, and Peter Hoskin

Subjects
Urology
Published
2023
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29. Metastases-directed stereotactic body radiotherapy in combination with targeted therapy or immunotherapy: systematic review and consensus recommendations by the EORTC–ESTRO OligoCare consortium

Author

Kroeze, Stephanie G C, primary, Pavic, Matea, additional, Stellamans, Karin, additional, Lievens, Yolande, additional, Becherini, Carlotta, additional, Scorsetti, Marta, additional, Alongi, Filippo, additional, Ricardi, Umberto, additional, Jereczek-Fossa, Barbara Alicja, additional, Westhoff, Paulien, additional, But-Hadzic, Jasna, additional, Widder, Joachim, additional, Geets, Xavier, additional, Bral, Samuel, additional, Lambrecht, Maarten, additional, Billiet, Charlotte, additional, Sirak, Igor, additional, Ramella, Sara, additional, Giovanni Battista, Ivaldi, additional, Benavente, Sergi, additional, Zapatero, Almudena, additional, Romero, Fabiola, additional, Zilli, Thomas, additional, Khanfir, Kaouthar, additional, Hemmatazad, Hossein, additional, de Bari, Berardino, additional, Klass, Desiree N, additional, Adnan, Shaukat, additional, Peulen, Heike, additional, Salinas Ramos, Juan, additional, Strijbos, Michiel, additional, Popat, Sanjay, additional, Ost, Piet, additional, and Guckenberger, Matthias, additional

Published
2023
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30. Genetic Aspects and Molecular Testing in Prostate Cancer: A Report from a Dutch Multidisciplinary Consensus Meeting

Author

Mehra, Niven, primary, Kloots, Iris, additional, Vlaming, Michiel, additional, Aluwini, Shafak, additional, Dewulf, Els, additional, Oprea-Lager, Daniela E., additional, van der Poel, Henk, additional, Stoevelaar, Herman, additional, Yakar, Derya, additional, Bangma, Chris H., additional, Bekers, Elise, additional, van den Bergh, Roderick, additional, Bergman, Andries M., additional, van den Berkmortel, Franchette, additional, Boudewijns, Steve, additional, Dinjens, Winand N.M., additional, Fütterer, Jurgen, additional, van der Hulle, Tom, additional, Jenster, Guido, additional, Kroeze, Leonie I., additional, van Kruchten, Michel, additional, van Leenders, Geert, additional, van Leeuwen, Pim J., additional, de Leng, Wendy W.J., additional, van Moorselaar, R. Jeroen A., additional, Noordzij, Walter, additional, Oldenburg, Rogier A., additional, van Oort, Inge M., additional, Oving, Irma, additional, Schalken, Jack A., additional, Schoots, Ivo G., additional, Schuuring, Ed, additional, Smeenk, Robert J., additional, Vanneste, Ben G.L., additional, Vegt, Erik, additional, Vis, André N., additional, de Vries, Kim, additional, Willemse, Peter-Paul M., additional, Wondergem, Maurits, additional, and Ausems, Margreet, additional

Published
2023
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34. Comparing Patient-Reported Outcomes on Three-Ligament Tenodesis between Partial and Complete Scapholunate Ligament Injuries: A Cohort Study

Author

Stefanie N. Hakkesteegt, Mark J.W. van der Oest, Kas N. Dullemans, Liron S. Duraku, Caroline A. Hundepool, Ruud W. Selles, Reinier Feitz, J. Michiel Zuidam, R.A.M. Blomme, B.J.R. Sluijter, D.J.J.C. van der Avoort, A. Kroeze, J.M. Smit, J. Debeij, E.T. Walbeehm, G.M. van Couwelaar, Guus M. Vermeulen, J.P. de Schipper, J.F.M. Temming, J.H. van Uchelen, H.L. de Boer, K.P. de Haas, K. Harmsen, O.T. Zöphel, R. Koch, T.M. Moojen, X. Smit, G.J. Halbesma, R. van Huis, P.Y. Pennehouat, K. Schoneveld, Y.E. van Kooij, R.M. Wouters, P. Zagt, J. Veltkamp, A. Fink, W.A. de Ridder, J. Tsehaie, R. Poelstra, M.C. Janssen, P.O. Sun, V.J.M.M. Schrier, L. Hoogendam, J.S. Teunissen, Jak Dekker, M.L. Jansen-Landheer, M.H.P. ter Stege, J.S. Souer, R.W. Selles, H.P. Slijper, S.E.R. Hovius, R. Feitz, Plastic and Reconstructive Surgery and Hand Surgery, and Rehabilitation Medicine

Subjects
Orthopedics and Sports Medicine, Surgery
Abstract

Purpose: Multiple studies report outcomes after 3-ligament tenodesis (3-LT) in treating traumatic scapholunate interosseous ligament injury (SLIL). However, investigators do not differentiate between patients with partial or complete SLIL injury. The relation between the extent of SLIL disruption and surgical outcomes and if this should be considered when treating a patient with SLIL injury remains unknown. We aimed to evaluate differences in patient-rated wrist evaluation (PRWE) scores, satisfaction and return to work between patients with partial or complete chronic traumatic SLIL injury treated with 3 ligament tenodesis at 12 months after surgery. Methods: All patients with chronic SLIL injury (partial and complete) who were treated with 3-LT at our clinic and received the same postoperative management between December 2011 and December 2019 were studied. Only patients who had completed the PRWE and return to work questionnaires preoperatively and 12 months after surgery were included. Patients were allocated to the partial (classified as Geissler 2 or 3) or complete SLIL injury group (classified as Geissler 4) by retrospectively assessing wrist arthroscopy reports. Results: Thirty-nine patients with partial and 90 with complete SLIL injuries were included. At 1-year follow-up, PRWE scores had significantly improved in both groups. When adjusting for clinical baseline characteristics, there was no statistically significant difference between patients with partial or complete SLIL injury. Patients with complete SLIL injury had a 70% higher return to work within the first 12 months after 3-LT; however, satisfaction with the treatment result was similar for both study groups 1 year after surgery. Conclusions: Patients with complete and partial traumatic SLIL injury report better PRWE total scores at 12 months after 3-LT, but there was no statistically significant difference between the groups in PRWE scores or satisfaction with the treatment result. Type of study/level of evidence: Therapeutic IV.

Published
2022
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36. Imaging-Based Prevalence of Oligometastatic Disease: A Single-Center Cross-Sectional Study

Author

Christ, Sebastian M., primary, Pohl, Kaspar, additional, Muehlematter, Urs J., additional, Heesen, Philip, additional, Kühnis, Anja, additional, Willmann, Jonas, additional, Ahmadsei, Maiwand, additional, Badra, Eugenia Vlaskou, additional, Kroeze, Stephanie G.C., additional, Mayinger, Michael, additional, Andratschke, Nicolaus, additional, Huellner, Martin, additional, and Guckenberger, Matthias, additional

Published
2022
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37. Is Early Active Motion After 3-Ligament Tenodesis Noninferior to Late Active Motion? A Prospective, Multicenter Cohort Study

Author

Bakker, Daniel, primary, Colaris, Joost W., additional, Kraan, Gerald A., additional, Mathijssen, Nina, additional, Selles, Ruud, additional, Smit, Xander, additional, Wouters, Robbert, additional, Blomme, R.A.M., additional, Sluijter, B.J.R., additional, van der Avoort, D.J.J.C., additional, Kroeze, A., additional, Smit, J., additional, Debeij, J., additional, Walbeehm, E.T., additional, van Couwelaar, G.M., additional, Vermeulen, G.M., additional, de Schipper, J.P., additional, Temming, J.F.M., additional, van Uchelen, J.H., additional, de Boer, H.L., additional, de Haas, K.P., additional, Harmsen, K., additional, Zöphel, O.T., additional, Feitz, R., additional, Souer, J.S., additional, Koch, R., additional, Hovius, S.E.R., additional, Moojen, T.M., additional, Smit, X., additional, van Huis, R., additional, Pennehouat, P.Y., additional, Schoneveld, K., additional, van Kooij, Y.E., additional, Veltkamp, J.J., additional, Fink, A., additional, De Ridder, W.A., additional, Slijper, H.P., additional, Selles, R.W., additional, Porsius, J.T., additional, Wouters, R.M., additional, Tsehaie, J., additional, Poelstra, R., additional, Jansen, M.C., additional, van der Oest, M.J.W., additional, Hoogendam, L., additional, Teunissen, J.S., additional, Dekker, J., additional, Jansen-Landheer, M., additional, ter Stege, M., additional, Zuidam, J.M., additional, van Nieuwenhoven, C.A., additional, Duraku, L.S., additional, Hundepool, C., additional, van der Heijden, B., additional, and Colaris, J.W., additional

Published
2022
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38. Comparing Patient-Reported Outcomes on Three-Ligament Tenodesis between Partial and Complete Scapholunate Ligament Injuries: A Cohort Study

Author

Hakkesteegt, Stefanie N., primary, van der Oest, Mark J.W., additional, Dullemans, Kas N., additional, Duraku, Liron S., additional, Hundepool, Caroline A., additional, Selles, Ruud W., additional, Feitz, Reinier, additional, Zuidam, J. Michiel, additional, Blomme, R.A.M., additional, Sluijter, B.J.R., additional, van der Avoort, D.J.J.C., additional, Kroeze, A., additional, Smit, J.M., additional, Debeij, J., additional, Walbeehm, E.T., additional, van Couwelaar, G.M., additional, Vermeulen, Guus M., additional, de Schipper, J.P., additional, Temming, J.F.M., additional, van Uchelen, J.H., additional, de Boer, H.L., additional, de Haas, K.P., additional, Harmsen, K., additional, Zöphel, O.T., additional, Koch, R., additional, Moojen, T.M., additional, Smit, X., additional, Halbesma, G.J., additional, van Huis, R., additional, Pennehouat, P.Y., additional, Schoneveld, K., additional, van Kooij, Y.E., additional, Wouters, R.M., additional, Zagt, P., additional, Veltkamp, J., additional, Fink, A., additional, de Ridder, W.A., additional, Tsehaie, J., additional, Poelstra, R., additional, Janssen, M.C., additional, Sun, P.O., additional, Schrier, V.J.M.M., additional, Hoogendam, L., additional, Teunissen, J.S., additional, Dekker, Jak, additional, Jansen-Landheer, M.L., additional, ter Stege, M.H.P., additional, Souer, J.S., additional, Selles, R.W., additional, Slijper, H.P., additional, Hovius, S.E.R., additional, and Feitz, R., additional

Published
2022
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39. Next-Generation Sequencing–Based Clonality Assessment of Ig Gene Rearrangements

Author

Hesham ElDaly, Nikos Darzentas, Frederic Davi, Michael Hummel, Ioannis Anagnostopoulos, Leonie I. Kroeze, Michiel van den Brand, Tomáš Reigl, Blanca Scheijen, Patricia J. T. A. Groenen, Jakub Paweł Porc, Jos Rijntjes, Falko Fend, Michèle Y. van der Klift, Kim C. Heezen, Julia Steinhilber, Hongxiang Liu, Anton W. Langerak, Markus Möbs, Jeroen A.C.W. Luijks, Radboud University Medical Center [Nijmegen], Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], University of Tübingen, Erasmus University Medical Center [Rotterdam] (Erasmus MC), Masaryk University [Brno] (MUNI), University Medical Center of Schleswig–Holstein = Universitätsklinikum Schleswig-Holstein (UKSH), Kiel University, Service d'Hématologie clinique [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Coventry University, Cairo University, Cambridge University Hospitals - NHS (CUH), and University of Cambridge [UK] (CAM)

Subjects
0301 basic medicine, clone (Java method), Validation study, Concordance, Computational biology, Gold standard (test), Biology, Immunoglobulin light chain, DNA sequencing, 3. Good health, Pathology and Forensic Medicine, Fragment size, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Multiplex polymerase chain reaction, Molecular Medicine, ComputingMilieux_MISCELLANEOUS, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract

Ig gene (IG) clonality analysis has an important role in the distinction of benign and malignant B-cell lymphoid proliferations and is mostly performed with the conventional EuroClonality/BIOMED-2 multiplex PCR protocol and GeneScan fragment size analysis. Recently, the EuroClonality-NGS Working Group developed a method for next-generation sequencing (NGS)–based IG clonality analysis. Herein, we report the results of an international multicenter biological validation of this novel method compared with the gold standard EuroClonality/BIOMED-2 protocol, based on 209 specimens of reactive and neoplastic lymphoproliferations. NGS-based IG clonality analysis showed a high interlaboratory concordance (99%) and high concordance with conventional clonality analysis (98%) for the molecular conclusion. Detailed analysis of the individual IG heavy chain and kappa light chain targets showed that NGS-based clonality analysis was more often able to detect a clonal rearrangement or yield an interpretable result. NGS-based and conventional clonality analysis detected a clone in 96% and 95% of B-cell neoplasms, respectively, and all but one of the reactive cases were scored polyclonal. We conclude that NGS-based IG clonality analysis performs comparable to conventional clonality analysis. We provide critical parameters for interpretation and discuss a first step toward a quantitative scoring approach for NGS clonality results. Considering the advantages of NGS-based clonality analysis, including its high sensitivity and possibilities for accurate clonal comparison, this supports implementation in diagnostic practice.

Published
2021
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41. CLINICAL SPECTRUM OF PRECURSOR B-CELL LYMPHOBLASTIC MALIGNANCIES: A LARGE COHORT STUDY OF 364 PEDIATRIC PATIENTS

Author

Kroeze, E., primary, Bakker, M., additional, Boer, J., additional, Hagleitner, M., additional, Burkhardt, B., additional, Padilla, L., additional, Mori, T., additional, Attarbaschi, A., additional, Verdú-Amorós, J., additional, Pillon, M., additional, Anderzhanova, L., additional, Kabíčková, E., additional, Chiang, A., additional, Kebudi, R., additional, Mellgren, K., additional, Lasic, J., additional, Jazbec, J., additional, Meijerink, J., additional, Beishuizen, A., additional, and Loeffen, J., additional

Published
2022
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43. Prevalence and Risk Factors for Postoperative Complications Following Open A1 Pulley Release for a Trigger Finger or Thumb

Author

Koopman, Jaimy E., primary, Zweedijk, Bo E., additional, Hundepool, Caroline A., additional, Duraku, Liron S., additional, Smit, Jeroen, additional, Wouters, Robbert M., additional, Selles, Ruud W., additional, Zuidam, J. Michiel, additional, van der Avoort, D.J.J.C., additional, Blomme, R.A.M., additional, de Boer, H.L., additional, van Couwelaar, G.M., additional, Debeij, J., additional, Dekker, J., additional, van Ewijk, F.J., additional, Feitz, R., additional, Fink, A., additional, de Haas, K.P., additional, Harmsen, K., additional, Hoogendam, L., additional, Hovius, S.E.R., additional, van Huis, R., additional, Jansen-Landheer, M.L., additional, Koch, R., additional, van Kooij, Y.E., additional, Kroeze, A., additional, Moojen, T.M., additional, van der Oest, M.J.W., additional, Pennehouat, P.Y., additional, de Ridder, W.A., additional, de Schipper, J.P., additional, Schoneveld, K., additional, Slijper, H.P., additional, Sluijter, B.J.R., additional, Smit, X., additional, Souer, J.S., additional, ter Stege, M., additional, Temming, J.F.M., additional, Teunissen, J.S., additional, van Uchelen, J.H., additional, Veltkamp, J.J., additional, Vermeulen, G.M., additional, Walbeehm, E.T., additional, and Zöphel, O.T., additional

Published
2022
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44. Return to Usual Work Following an Ulnar Shortening Osteotomy: A Sample of 111 Patients

Author

Teunissen, Joris Sebastiaan, primary, Feitz, Reinier, additional, Al Shaer, Sanharib, additional, Hovius, Steven, additional, Selles, Ruud W., additional, Van der Heijden, Brigitte, additional, Blomme, R.A.M., additional, Sluijter, B.J.R., additional, Halbesma, G.J., additional, van der Avoort, D.J.J.C., additional, Kroeze, A., additional, Smit, J., additional, Debeij, J., additional, Walbeehm, E.T., additional, van Couwelaar, G.M., additional, de Schipper, J.P., additional, Temming, J.F.M., additional, van Uchelen, J.H., additional, de Boer, H.L., additional, de Haas, K.P., additional, Harmsen, K., additional, Souer, J.S., additional, Koch, R., additional, Moojen, T.M., additional, Smit, X., additional, Zuidam, J.M., additional, van Huis, R., additional, Pennehouat, P.Y., additional, Schoneveld, K., additional, van Kooij, Y.E., additional, Zagt, P., additional, van Ewijk, F.J., additional, Veltkamp, J.J., additional, Fink, A., additional, de Ridder, W.A., additional, Slijper, H.P., additional, Tsehaie, J., additional, Poelstra, R., additional, Jansen, M.C., additional, van der Oest, M.J.W., additional, Hoogendam, L., additional, Dekker, J., additional, Jansen-Landheer, M., additional, ter Stege, M., additional, and Wouters, R.W., additional

Published
2022
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45. Metastasis-Free Survival and Patterns of Distant Metastatic Disease After Prostate-Specific Membrane Antigen Positron Emission Tomography (PSMA-PET)-Guided Salvage Radiation Therapy in Recurrent or Persistent Prostate Cancer After Prostatectomy

Author

Zamboglou, Constantinos, primary, Strouthos, Iosif, additional, Sahlmann, Joerg, additional, Farolfi, Andrea, additional, Serani, Francesca, additional, Medici, Federica, additional, Cavallini, Letizia, additional, Morganti, Alessio Guiseppe, additional, Trapp, Christian, additional, Koerber, Stefan A., additional, Peeken, Jan C., additional, Vogel, Marco M.E., additional, Schiller, Kilian, additional, Combs, Stephanie E., additional, Eiber, Matthias, additional, Vrachimis, Alexis, additional, Ferentinos, Konstantinos, additional, Spohn, Simon K.B., additional, Kirste, Simon, additional, Gratzke, Christian, additional, Ruf, Juri, additional, Grosu, Anca-Ligia, additional, Ceci, Francesco, additional, Fendler, Wolfgang P., additional, Miksch, Jonathan, additional, Kroeze, Stephanie, additional, Guckenberger, Matthias, additional, Lanzafame, Helena, additional, Fanti, Stefano, additional, Hruby, George, additional, Wiegel, Thomas, additional, Emmett, Louise, additional, Schmidt-Hegemann, Nina Sophie, additional, and Henkenberens, Christoph, additional

Published
2022
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48. Impact of DNA damage repair defects on response to radium-223 and overall survival in metastatic castration-resistant prostate cancer

Author

Sjoerd van Helvert, Niven Mehra, Samhita Pamidimarri Naga, Maren Bormann, Inge M. van Oort, Leonie I. Kroeze, Emmanuel S. Antonarakis, Peter H.J. Slootbeek, Winald R. Gerritsen, Maarten J. van der Doelen, and Pedro Isaacsson Velho

Subjects
Male, 0301 basic medicine, Radium-223, Oncology, Cancer Research, medicine.medical_specialty, DNA Repair, DNA repair, DNA damage, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], DNA Mutational Analysis, Rare cancers Radboud Institute for Molecular Life Sciences [Radboudumc 9], medicine.disease_cause, Germline, Cohort Studies, 03 medical and health sciences, Prostate cancer, All institutes and research themes of the Radboud University Medical Center, 0302 clinical medicine, Prostate, Internal medicine, Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15], Biomarkers, Tumor, medicine, Humans, Neoplasm Metastasis, Aged, Retrospective Studies, Mutation, business.industry, High-Throughput Nucleotide Sequencing, Retrospective cohort study, Middle Aged, medicine.disease, Survival Analysis, Gene Expression Regulation, Neoplastic, body regions, Prostatic Neoplasms, Castration-Resistant, DNA Repair Enzymes, 030104 developmental biology, medicine.anatomical_structure, Urological cancers Radboud Institute for Health Sciences [Radboudumc 15], 030220 oncology & carcinogenesis, business, DNA Damage, Radium, medicine.drug
Abstract

Purpose Radium-223 is a targeted alpha radiation therapy for metastatic castration-resistant prostate cancer. DNA damage repair (DDR) defective prostate cancers, specifically genetic aberrations leading to homologous recombination deficiency (HRD), accumulate irreparable DNA damage following genotoxic treatment. This retrospective study assessed DDR mutation status in patients treated with radium-223, investigating their association with efficacy and overall survival (OS). Patients and methods Included patients were treated with radium-223 and had results from primary or metastatic tumour tissue of a comprehensive next-generation sequencing panel of DDR genes, including canonical HRD genes. Patients were grouped by presence (DDR+) or absence (DDR−) of pathogenic somatic or germline aberrations in DDR genes. We evaluated OS, time to ALP progression (TAP), time to initiation of subsequent systemic therapy (TST) and biochemical responses between DDR groups. Results Ninety-three patients were included. Twenty-eight (30%) patients had DDR mutations, most frequently in ATM (8.6%), BRCA2 (7.5%) and CDK12 (4.3%) genes. DDR+ patients showed prolonged OS (median 36.3 versus 17.0 months; HR 2.29; P = 0.01). Median TAP and TST in the DDR+ and DDR− patients was 6.9 versus5.8 months (HR = 1.48; P = 0.15), and 8.9 versus7.3 months (HR = 1.58; P = 0.08), respectively. DDR+ patients more frequently completed radium-223 therapy (79% versus 47%; P = 0.05). No difference in biochemical responses were seen. Conclusion Patients harbouring DDR aberrations showed significant OS benefit, and more commonly completed radium-223 therapy. These findings need prospective confirmation and support strategies of genotoxic agents such as radium-223 in patients harbouring DDR defects.

Published
2020
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