152 results on '"Lu Ma"'
Search Results
2. Association of NO2 with daily hospital admissions for mental disorders: Investigation of the modification effects of green spaces and long-term NO2 exposure
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Can Yang, Jing Wang, Haoming Yang, Jianpeng Liao, Xiaodie Wang, Kuizhuang Jiao, Xuxi Ma, Jingling Liao, Xingyuan Liu, and Lu Ma
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Psychiatry and Mental health ,Biological Psychiatry - Published
- 2022
3. Effect of surface acidity modulation on Pt/Al2O3 single atom catalyst for carbon monoxide oxidation and methanol decomposition
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Shaohua Xie, Xing Zhang, Peng Xu, Braden Hatcher, Yuxi Liu, Lu Ma, Steven N. Ehrlich, Sampyo Hong, and Fudong Liu
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General Chemistry ,Catalysis - Published
- 2022
4. Effectiveness of a multifaceted intervention for the improvement of nutritional status and nutrition knowledge of children in poverty-stricken areas in Shaanxi Province, China
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Cai Zhao, Lu Ma, Liwang Gao, Yan Wu, Yating Yan, Wen Peng, and Youfa Wang
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General Medicine - Published
- 2022
5. The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial
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Lu Ma, Xin Hu, Lili Song, Xiaoying Chen, Menglu Ouyang, Laurent Billot, Qiang Li, Alejandra Malavera, Xi Li, Paula Muñoz-Venturelli, Asita de Silva, Nguyen Huy Thang, Kolawole W Wahab, Jeyaraj D Pandian, Mohammad Wasay, Octavio M Pontes-Neto, Carlos Abanto, Antonio Arauz, Haiping Shi, Guanghai Tang, Sheng Zhu, Xiaochun She, Leibo Liu, Yuki Sakamoto, Shoujiang You, Qiao Han, Bernard Crutzen, Emily Cheung, Yunke Li, Xia Wang, Chen Chen, Feifeng Liu, Yang Zhao, Hao Li, Yi Liu, Yan Jiang, Lei Chen, Bo Wu, Ming Liu, Jianguo Xu, Chao You, Craig S Anderson, Thompson Robinson, J. Jaime Miranda, Craig S. Anderson, Adrian Parry-Jones, Nikola Sprigg, Sophie Durrans, Caroline Harris, Ann Bamford, Olivia Smith, Robert Herbert, Christopher Chen, William Whiteley, Rong Hu, Jayanthi Mysore, Yao Zhang, Stephen Jan, Hueiming Liu, Lingli Sun, Honglin Chu, Anila Anjum, Francisca Gonzalez Mc Cawley, Alejandra Del Rio, Bruna Rimoli, Rodrigo Cerantola, Thanushanthan Jeevarajah, Madhushani Kannangara, Andrene Joseph, Chamath Nanayakkara, Chunmiao Zhang, Zhao Yang, Brook Li, Zhuo Meng, Yi Ning, Le Dong, Manuela Armenis, Joyce Lim, Helen Monaghan, Rui Luo, Guojuan Cheng, Yilin Dong, Ziqin Liu, Shuihong Wang, Ying Zhang, Jipeng Cheng, Hui Shi, Wenjing Li, Langming Mou, Ping Yi, Xue Chen, Shalomi Weerawardena, Poornima Ellawala, Enalee Ranasinghe, Chrishmi Rodrigo, Kolawala Wahab, Sunday Adeniyi, Jeyaraj Pandian, Megha Khanna, Paula Muñoz Venturelli, Francisca González, Francisca Urrutia Goldsack, Dilshad Begum, Octavio Pontes-Neto, Millene Camilo, Francisco Dias, Octavio Vincenzi, Carla Moro, Renata Santos, Nara Texeira, Alexandre Longo, Rafaela Liberato, Sheila Martins, Arthur Pille, Bruna Chwal, Isabel Silva, Natacha Titton, Gustavo Weiss, Daissy Mora, Magda Ouriques, Leonardo Carbonera, Rodrigo Bazan, Gabriel Modolo, Fernanda Winckler, Luana Miranda, Juli Souza, Alexis Rojo, Wilhelm Uslar, Lorena Medel, Javiera Lopez, Diego Herrero, Pablo Lavados, Barbara Vargas Latorre, Nathalie Conejan, Tomas Esparza, Patricio Sotomayor, Denisse Wenger, Juan Pablo Gigoux, Aldo Letelier, Lilian Acevedo, Vivianne Moya, Cristian Figueroa, Nicol Vallejos, Rodrigo Guerrero, Mauricio Velasquez, Jose Vallejos, Kimerly Pallauta, Tamara Santibanez, Angelo Queirolo, Andrea Lobos, Yongming Jiang, Weimin Li, Wei Huang, Ke Luo, Gangying Liu, Guang Yang, Hongtao Jiang, Xu Zhang, Hongyan Jing, Bo Pu, Dong Lv, Hui Kang, Qiuping Hu, Xiaoming Jiang, Yanli Chen, Shenghua Yang, Jianjun He, Zongping Li, Gang Cheng, Hailin Huang, Xiaoyi Wang, Jianqiong Lin, Minhui Chen, Chenghao Yang, Hao Ding, Yunliang Deng, Fei Luo, Rongjun Zhang, Xiaofeng Wang, Hongbing Zhang, Xiaoliang Yang, Yang Zhang, Chengyi Yang, Yu He, Feng Liu, Rongjie Wang, Yuhui Zhang, Xiaodong Xin, Bin Feng, Wanru Hao, Chang Song, Yun Guo, Dehua Jiang, Jie Chen, Changtong Tang, Hongliang Zhu, Xin Li, Jin Cui, Haidong Xu, Boyang Li, Fusheng Tang, Yuanbin Li, Min Gao, Bo Yang, Xuejun Xu, Bing Deng, Yi Zheng, Yuanhong Ge, Keyu Chen, Yang Liu, Xinshen Li, Tingting Zhong, Jianfeng Xu, Hai Zhang, Jiyue Wang, Jianxin Zhu, Hanyu Sun, Fuhua Yu, Xueguang Zhang, Mingsen Zhang, Bin Wang, Yiming Ma, Donglin Jiang, Jun Zhou, Cong Liu, Wenhong Nie, Mingguo Li, Tao Tian, Yong Li, Mingfang He, Xiaolong Tu, Zhengjun Wu, Hong Liu, Dongsheng Zhong, Rongcai Jiang, Jian Sun, Ye Tian, Yingsheng Wei, Shuo An, Pingbo Wei, Le Luo, Bin Lin, Gang Liu, Yan Wen, Qiang Cai, Qianxue Chen, Pan Lei, Zhiyang Li, Meifang Zhang, Jiaquan He, Yan Chen, Jun Liu, Xinghai Liu, Junyan Li, Min Chen, Jing Wang, Bingzhi Zhou, Baichun Ye, Jiancheng Zhang, Manyuan Zhang, Xuming Pan, Xiaoxiang Yu, Jian Xu, Qingbao Xiao, Yuefei Wang, Liang Tao, Lin Shi, Niandong Zheng, Guoliang You, Bo Lei, Shu Chen, Honggang Wu, Jin Hu, Jianlan Zhao, Jian Yu, Qiang Yuan, Zhuoying Du, Xielin Tang, Qianke Li, Shenghua Liu, Feilong Yang, Kui Xiao, Chao Luo, Guang Wang, Xudong Che, Zhipeng Teng, Wenwu Wan, Jun Li, Yu Liu, Mingbo Fan, Tao Zhang, Lun Cai, Yuan Ma, Zhifeng Ma, Bin Li, Linlin He, Jinghui Li, Weibing Zhang, Shuxin Zhang, Hongzhen Zhang, Yingguang Dai, Jun Lei, Lei Mao, Yiyang Huang, Zhi Zhou, Ping Chen, Fang Chen, Pan Wei, Tiangui Li, Honglin Chen, Mengfei Zeng, Kejie Mou, Jun Xue, Yong Jiang, Xiaoping Tang, Tao Chen, Yalan Zhang, Yanbing Xu, Yuchen Gu, Yujun Zhao, Bin Yang, Peng Kuai, Xi Wang, Yuwang Yang, Xueling Hu, Huitian Zhang, Yintao Yang, Weifeng Wang, Junyi Zhang, Wei Cheng, Xiaoxue Zhang, Xiaowen Ma, Qin He, Li Zhang, Rong Gao, Huixiang Liu, Jingwei Ye, Ping Xu, Xin Wu, Yuan Yuan, Peng Zou, Zhen Zhang, Jiyong Cheng, Zhangming Zhou, Yijun Zeng, Zhang Liang, Deming Du, Shui Yu, Yongjun Cao, Jiaping Xu, Zhichao Huang, Dongqin Chen, Wenfeng Xiao, Li Zhu, Miao Yuan, Yuhai Wang, Dongliang Shi, Xu Hu, Dingchao Xiang, Like Shi, Hongqin Wang, Liu Yang, Wang Miao, Yiyi Hu, Yuchun Zhao, Xi Hu, Weiduo Zhou, Chao Sun, Dong Tang, Kun Yao, Jin You, Shishi Chen, Jianmin Yao, Huanmei Li, Jinmei Liu, Ailin Bai, Yong Yi, Qingshan Deng, Peng Luo, Han Wang, Jingcheng Jiang, Qingwei Yang, Shunpo He, Jun Wang, Yu Chen, Hua He, Yuyang Deng, Zhikai Cao, Xuxia Yi, Jinbiao Luo, Shuang Luo, Min Gong, Li Liu, Xuejun Gao, Jia Liu, Li'e Wu, Jia Zhang, Hongying Sun, Xinhui Li, Lu Jia, Jianbing Wu, Jie Zhang, Huajun Zhang, Chunfu Du, Shun Li, Xiaobin Yang, Jie He, Lei Liao, Gezhi Zhou, Wentao Dong, Yunxiang Chen, Xiaofeng Lin, Xujian Shui, Peng Zhang, Yuan Zhao, Hongli Yang, Wenbin Zhao, Xiaoyi Zhang, Jincao Chen, Qian Wu, Xuan Dai, Baogui Tang, Yinjuan Wang, Tao Liu, Haixia Zhang, Faliang Duan, Ming Luo, Qingfang Jiao, Guoliang Lei, Dong Wang, Chunwang Song, Haopeng Tan, Feng Ye, Xinghu Qin, Xiaolong Liang, Junling Liu, Lang Yang, Jie Yang, Yapeng Lin, Qian Yang, Xuntai Ma, Yinkuang Qi, Baogen Pan, Caixia Jiang, Zhanying Ye, Ce Dong, Xiongfei Yue, Xiaopeng Yang, Tuoheti Maimaitiyiming, Jun Dong, Yonggang Wu, Feng Gao, Deqiang Zhao, Xinghai Zhang, PengJun Wang, Hongbo Jiang, Jianping Li, Wei Zhang, Jing Chen, Haibo Tong, Yonghong Wang, Kaipeng Qiao, Fuyou Guo, Mingchu Zhang, Yan Hu, Mengzhao Feng, Dengpan Song, Yi Zuo, Shangjun Chen, Chao Qian, Baoming Li, Jingku Ma, Sunfu Zhang, Bin Kong, Xingyu Dong, Sheng Fang, Bin Lu, Yang Li, Yongling Yang, Hong Yu, Huaiyu Sun, Yue Wang, Weimin Wang, Tong Li, Shengli Li, Zhiming Xu, Yongyi Wang, Qiang Dong, Yuping Tang, Heling Chu, Ying Lu, Zhong Wang, Xiaoou Sun, Jianhua Zhao, Shuaifeng Yang, Xiying Qian, Aralikatte Onkarappa Saroja, Ravishankar Naik k, Sandip Chindhi, Nakul Pampaniya, Kurubara Amaresh, Thomas Iype, Dileep R, Reeja Rajan, Praveen Panicker, Rupjyoti Das, Nupur Choudhury, Pankaja Gohain, Jemin Webster, Biyol Pakma, Lalbiak Sangi, Ivy Sebastian, Gaurav Aggrawal, Komal Raj, Deepankshi Rajoura, Sulena Singh, Varun Aggrawal, Amit Narang, Vanesa Cano-Nigenda, Diego López-Mena, Héctor Valdez-Ruvalcaba, Roberto Toledo-Treviño, Reginald Obiako, Sani Abubakar, Oguike Emeka, Balogun Olayemi, Melika Lois, Ibinaiye Philip, Olurishe Comfort O, Njideka Okubadejo, Osigwe Agabi, Oluwadamilola Ojo, Kolawole Wahab, Abiodun Bello, Oyinloye Ibukun, Olufemi Sanayaolu, Abdulraheem Jimoh, Shahid Waheed, Dr.Ayeesha Kamal, Raja Farhat Shoaib, Fizza Orooj, Sadaf Majid, Taskeen Zehra, Abdus Salam Khan, Ravi Shanker, Nadir Ali Syed, Nashwa Ahmad, Ana Valencia, Danny Barrientos, Jorge Ramirez, Pilar Calle, Dilum Palliyeguruge, Sumudu Muthucumarana, Shiroma Ratnayaka, Dilhara Ganihiarachchi, Arundathi Bandaranayake, S.D.B Somaratne, Saumya Narayana, Sithara Gallage, Bimsara Senanayake, Udari Samarasiri, Dunya Luke, Mythily Sivapathasundaram, Vithoosan Sahadevan, Amani Rasmi, Yuran Deshaka, Nilukshi Fernando, Aruna Munasinghe, Kapilanga Rathnapriya, A.S Nissanka, Kanchana Karunathilake, Isuru Gayan, Kaminda Wijenayake, Hasitha Gunasekara, Jagath Vidyarathne, Ajantha Keshavaraj, Kanagasabapathy Janarthanan, Arhivalaky Gerald Jeevathasan, Sivaram Sivamainthan, Mathyamuthan John Priyanth, Abirami John Priyanth, Thambippillai Rajendiran, Sanjeewa Alwis, Nushara Gunasekare, Vasundara Liyanarachchi, Athula Dissanayake, Wimalasiri Mewa Uluwattage, Gimhani Ratnayake, Charika Rajinee, Sakura Jayawardana, Janaka Peiris, Ranjith Wicramasinghe, Chamila Fernando, Jessie Abbas, Nethmini Withanage, Makaranda Bandara, Duy Ton Mai, Van Chi Nguyen, Viet Phuong Dao, Xuan Trung Vuong, Tien Dung Nguyen, Trung Hieu Dinh, Ha Quan Phan, Quoc Viet Bui, Dinh Tho Phung, Quang Tho Pham, Dinh Dai Pham, Duc Thuan Do, Phuc Duc Dang, Minh Duc Dang, Dang Hai Nguyen, Thi Phuong Nga Nguyen, Quoc Huy Nguyen, Quoc Dai Pham, Quoc Vinh Chau, Vinh Thy Van Tai, Tran Vinh Le, Cong Tri Le, Ha Mai Khuong Tran, Huu Khanh Nguyen, Hoang Minh Thao Ngyen, Duc Chien Vo, Thai My Phuong Nguyen, Trung Thanh Tran, Thi Hanh Vi Vo, Hao Nhien Cao, Ba Thang Nguyen, Thi Ngoc Suong Le, Thien Duc La, Chi Duc Pham, and Huy Thai
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General Medicine - Published
- 2023
6. Effect of extended duration of thromboprophylaxis for medically ill patients
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Xing Wang, Yuqi Chen, Dingke Wen, Chao You, and Lu Ma
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Internal Medicine - Published
- 2023
7. Association between body mass index and body fat measured by dual-energy X-ray absorptiometry (DXA) in China: systematic review and meta-analysis
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Xiaomin Sun, Na Yan, Wen Peng, Tuan T Nguyen, Lu Ma, and Youfa Wang
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General Medicine - Published
- 2023
8. Constructing a Si-CuO core-shell nanowire heterojunction photoanode for enzyme-free and highly-sensitive glucose sensing
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Ruoxi Zhang, Shengchen Ke, Wenxiang Lu, Weijian Zhu, Lu Ma, Linling Qin, Shaolong Wu, and Xiaofeng Li
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General Physics and Astronomy ,Surfaces and Interfaces ,General Chemistry ,Condensed Matter Physics ,Surfaces, Coatings and Films - Published
- 2023
9. Structure-activity relationship of Pt catalyst on engineered ceria-alumina support for CO oxidation
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Shaohua Xie, Wei Tan, Chunying Wang, Hamidreza Arandiyan, Magnus Garbrecht, Lu Ma, Steven N. Ehrlich, Peng Xu, Yaobin Li, Yan Zhang, Samantha Collier, Jiguang Deng, and Fudong Liu
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Physical and Theoretical Chemistry ,Catalysis - Published
- 2022
10. Research on Factors Affecting Deflection and Calculation Method of Web Stress for Steel Octagon-Web Beam
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Shan Chang, Ling Yuan, Bi Sun, Lu Ma, and Weidong Wu
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- 2023
11. Customized Hourglass-Shaped Channels in a Copper(Ii)-Organic Framework for One-Step Ethylene Purification from Ethylene/Ethane/Acetylene Ternary Mixtures with High Adsorption Capacity
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Lu-Lu Ma, Jiaqi Liu, Qian Xu, Hao Wang, Guo-Ping Yang, and Yaoyu Wang
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- 2023
12. Towards Self-Driven and Enzyme-Free Sweat Glucose Photoelectrochemical Sensing Via Decorating Cuo Nanoparticles on Tio2 Hierarchical Nanotubes
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Shengchen Ke, Linlin Qin, Ruoxi Zhang, Weijian Zhu, Wenxiang Lu, Lu Ma, Shaolong Wu, and Xiaofeng Li
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- 2023
13. Fabrication, Characterization and Performance Evaluation of Screen-printed Carbon Electrodes: Determination of Acetaminophen in Tylenol
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Yi He, Da Qin, Lu-Lu Ma, Xiao-Jiang Xie, Anthony Chang, Yan Zheng, and Alexander Huang
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chemistry ,X-ray photoelectron spectroscopy ,Scanning electron microscope ,Electrode ,chemistry.chemical_element ,Graphite ,Cyclic voltammetry ,Electrochemistry ,Carbon ,Redox ,Analytical Chemistry ,Nuclear chemistry - Abstract
Screen-printed carbon electrodes (SPCEs) were fabricated and compared with the commercial DS 110 (DropSens). In addition to the classic cyclic voltammetry (CV) of K3[Fe(CN)6], a method using widely available Bausch + Lomb and Tylenol was developed for comprehensive evaluation of the electrochemical performance of SPCEs. Scanning electron microscope (SEM) images showed that the graphite surface of the in-house SPCEs, which acted as reaction surface, was covered by grainy binders thus less reactive than DS 110. X-ray photoelectron (XPS) spectra indicated that both were composed primarily of graphite (> 85%), but the concentrations of S (detected in DS110 only), N and Cl in the less-electroactive binders differed. The CV using K3[Fe(CN)6] as probe revealed that the peak-to-peak separation of the in-house SPCE (0.140 V) was further apart than that of DS 110 (0.075 V). The oxidation and reduction peak currents of the in-house SPCE were 73% and 82% of that of the DS 110, respectively. When CV was applied to the determination of acetaminophen in Tylenol (product label concentration: 661 mmol/L) using Bausch + Lomb solution with 1 mol/L KCl as the buffer, DS 110 showed better sensitivity, but the in-house SPCE was stable and more precise. Though DS 110 displayed higher current and thus more sensitive, the in-house SPCE current was stable and thus more precise. The concentrations obtained from oxidation and reduction peaks were (775 ± 80) mmol/L and (686 ± 322) mmol/L for DS 110, and (637 ± 39) mmol/L and (713 ± 139) mmol/L for in-house SPCE, respectively. Moreover, DS 110 exhibited two large unknown peaks and thus less reliable in the acetaminophen-in-Tylenol CV test. Determination of acetaminophen in real Tylenol sample was helpful as additional quality control in SPCEs fabrication.
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- 2021
14. Silica modulated palladium catalyst with superior activity for the selective catalytic reduction of nitrogen oxides with hydrogen
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Shaohua Xie, Yuejin Li, Chunying Wang, Ke-Bin Low, Kailong Ye, Daekun Kim, Xing Zhang, Yaobin Li, Yan Zhang, Fengyuan Shi, Lu Ma, Steven N. Ehrlich, and Fudong Liu
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Process Chemistry and Technology ,Catalysis ,General Environmental Science - Published
- 2023
15. Establishment of X-ray diffraction fingerprints for identification of different configuration Realgar and its antitumor activity
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Ke YAN, Ying WANG, Bao-Fei YAN, Yu-Lu MA, Yue-Dong YANG, Shi-Lin DAI, Fang FANG, Si-Cheng WU, Xiu-Xiu WANG, Heng-Bin WANG, Dan YANG, Liu-Qing DI, Hai-Bo CHENG, Jia LIU, and Sheng-Jin LIU
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Analytical Chemistry - Published
- 2023
16. Efficacy and safety of Shenyankangfu Tablet, a Chinese patent medicine, for primary glomerulonephritis: A multicenter randomized controlled trial
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Ming Chen, Jun-zhou Fu, Shuwei Duan, Rong Wang, Wenhu Liu, Xusheng Liu, Meng Liang, Wei Li, Ping Luo, Xiao-Hong Cheng, Xiangmei Chen, Li-qun Song, Ying Li, Jun Zhu, Zhiyong Guo, Ying Lu, Yun Li, Rong-shan Li, Li-Hua Wang, Niansong Wang, Yongli Zhan, Zhang Hao, Zhaohui Ni, Hongli Lin, Shan Lin, Qiang He, Jing-Ai Fang, Guangyan Cai, Qiao-ling Zhou, Ji-feng Sun, Ji-ning Gao, Changying Xing, Lu Ma, Jian Chen, Ai-ping Yin, Yueyi Deng, Li-qun He, Yani He, Jie Wu, Gengru Jiang, Hong-yu Chen, Hong-Tao Yang, Qing Zhu, and Shi-ren Sun
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Losartan Potassium ,China ,medicine.medical_specialty ,Urology ,Renal function ,Nonprescription Drugs ,law.invention ,Glomerulonephritis ,Double-Blind Method ,Randomized controlled trial ,law ,medicine ,Humans ,Proteinuria ,business.industry ,General Medicine ,medicine.disease ,Clinical trial ,Treatment Outcome ,Losartan ,medicine.symptom ,business ,Drugs, Chinese Herbal ,Tablets ,medicine.drug ,Kidney disease - Abstract
Shenyankangfu Tablet (SYKFT) is a Chinese patent medicine that has been used widely to decrease proteinuria and the progression of chronic kidney disease.This trial compared the efficacy and safety of SYKFT, for the control of proteinuria in primary glomerulonephritis patients, against the standard drug, losartan potassium.This was a multicenter, double-blind, randomized, controlled clinical trial. Primary glomerulonephritis patients, aged 18-70 years, with blood pressure ≤ 140/90 mmHg, estimated glomerular filtration rate (eGFR) ≥ 45 mL/min per 1.73 mThe primary outcome was change in the 24-hour proteinuria level, after 48 weeks of treatment.A total of 735 participants were enrolled. The percent decline of urine protein quantification in the SYKFT group after 48 weeks was 8.78% ± 2.56% (P = 0.006) more than that in the losartan 50 mg group, which was 0.51% ± 2.54% (P = 1.000) less than that in the losartan 100 mg group. Compared with the losartan potassium 50 mg group, the SYKFT plus losartan potassium 50 mg group had a 13.39% ± 2.49% (P 0.001) greater reduction in urine protein level. Compared with the losartan potassium 100 mg group, the SYKFT plus losartan potassium 100 mg group had a 9.77% ± 2.52% (P = 0.001) greater reduction in urine protein. With a superiority threshold of 15%, neither was statistically significant. eGFR, serum creatinine and serum albumin from the baseline did not change statistically significant. The average change in TCM syndrome score between the patients who took SYKFT (-3.00 [-6.00, -2.00]) and who did not take SYKFT (-2.00 [-5.00, 0]) was statistically significant (P = 0.003). No obvious adverse reactions were observed in any group.SYKFT decreased the proteinuria and improved the TCM syndrome scores of primary glomerulonephritis patients, with no change in the rate of decrease in the eGFR. SYKFT plus losartan potassium therapy decreased proteinuria more than losartan potassium therapy alone.NCT02063100 on ClinicalTrials.gov.
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- 2021
17. Optimizing amla (Phyllanthus emblica) fruit powder supplementation in liquid feed fed to Holstein dairy calves: Insights from growth performance and health events
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Mebrahtom Nguse, Yi Yang, Zilin Fu, Jianchu Xu, Lu Ma, and Dengpan Bu
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Animal Science and Zoology - Published
- 2023
18. Identification of biomarkers for risk assessment of arsenicosis based on untargeted metabolomics and machine learning algorithms
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Jin Zhang, Lu Ma, Boyan Li, Xiong Chen, Dapeng Wang, and Aihua Zhang
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Environmental Engineering ,Environmental Chemistry ,Pollution ,Waste Management and Disposal - Published
- 2023
19. Macrophages promote heat stress nephropathy in mice via the C3a-C3aR-TNF pathway
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Yang Yang, Dongjuan Zhang, Minghui Song, Chao Wang, Jiayi Lv, Jie Zhou, Meihan Chen, Lu Ma, and Changlin Mei
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Immunology ,Immunology and Allergy ,Hematology - Published
- 2023
20. Effects of ambient air pollution on cause-specific hospitalizations in Wuhan during 2017–2019
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Jing Wang, Zenghui Huang, Xingyuan Liu, Can Yang, Haomin Yang, Jianpeng Liao, Kuizhuang Jiao, Qihao Chen, Xuxi Ma, Jingling Liao, and Lu Ma
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Health, Toxicology and Mutagenesis ,Public Health, Environmental and Occupational Health ,General Medicine ,Pollution - Published
- 2023
21. Protocol to develop a microfluidic human corneal barrier-on-a-chip to evaluate the corneal epithelial wound repair process
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Zitong Yu, Rui Hao, Xi Chen, Lu Ma, Yi Zhang, and Hui Yang
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General Immunology and Microbiology ,General Neuroscience ,General Biochemistry, Genetics and Molecular Biology - Published
- 2023
22. MnOx/g-C3N4 nanocomposites mediated sulfite activation for enhanced organic pollutants degradation under visible light irradiation
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Wenqiang Gong, Qinghong Wu, Lu Ma, Wenyu Zhang, Xiaoxia Li, Aihua Xu, and Shuaiqi Zhao
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Colloid and Surface Chemistry - Published
- 2023
23. Hydrothermal-assisted grinding route for WS2 quantum dots (QDs) from nanosheets with preferable tribological performance
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Lu Ma, Zhi-Lin Cheng, and Zan Liu
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Materials science ,02 engineering and technology ,General Chemistry ,Tribology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Hydrothermal circulation ,0104 chemical sciences ,Nanomaterials ,Grinding ,Chemical engineering ,Quantum dot ,Grease ,Lubrication ,0210 nano-technology ,Asperity (materials science) - Abstract
The 2D nanomaterials have achieved the superlubrication property whatever in solid or liquid lubrication in recent years. However, whether or not the nanosheets can stably disperse in oils and smoothly enter into the asperity of friction pairs is crucial for exerting the function of antifriction. The structure of 2D QDs is desirable for addressing these issues due to its smaller 3D size. In this study, we developed a facile preparation process for WS2 QDs with uniform 2 nm size from nanosheets via hydrothermal-assisted grinding approach. The structure of the as-obtained WS2 QDs was determined by a series of characterizations. The results showed that the as-obtained WS2 QDs exhibited the typical spectrum features of nanosized quantum dot. The results of the tribological performance in grease verified that the average friction coefficient (ACOFs) and wear volume (AWVs) were decreased by 7.89% and 63.90% relative to grease, respectively, exhibiting a preferable friction reducing and wear resistance.
- Published
- 2021
24. Tfr-Tfh index: A new predicator for recurrence of hepatocellular carcinoma patients with HBV infection after curative resection
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Xiao-Lu Ma, Xin-Rong Yang, Beili Wang, Jia Fan, Wei Guo, Shuang-Jian Qiu, Baishen Pan, Jie Zhu, and Jian Zhou
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0301 basic medicine ,Oncology ,Hepatitis B virus ,medicine.medical_specialty ,Carcinoma, Hepatocellular ,Clinical Biochemistry ,Biochemistry ,03 medical and health sciences ,0302 clinical medicine ,Immune system ,Internal medicine ,Follicular phase ,Tumor Microenvironment ,medicine ,Humans ,Clinical significance ,Tumor microenvironment ,Receiver operating characteristic ,business.industry ,Liver Neoplasms ,Biochemistry (medical) ,Cancer ,T-Lymphocytes, Helper-Inducer ,General Medicine ,medicine.disease ,digestive system diseases ,Log-rank test ,030104 developmental biology ,030220 oncology & carcinogenesis ,Hepatocellular carcinoma ,Neoplasm Recurrence, Local ,business - Abstract
Background T follicular helper (Tfh) cells and T follicular regulatory (Tfr) cells were newly identified as the subsets of cluster of CD4+ T cells. As major components of human immune system, they were found in tumor microenvironment and reported to play vital roles in the progression of cancer. But their clinical significance in Hepatocellular carcinoma (HCC) was not elucidated. Thus, this research aimed to investigate their prognostic value in HCC. Materials and methods A total of 210 subjects (including 110 HCC patients, 50 chronic hepatitis patients and 50 healthy individuals) were enrolled in the research. Tfh, Tfr cells and Treg cells from peripheral blood were measured by flow cytometry. Receiver operating characteristic (ROC) curves were used to evaluate the diagnostic performance of Tfr-Tfh Index (TTI) in early HCC and relapse status. Its further prognostic valve was assessed by Kaplan-Meier survival estimate and log rank tests. Results Tfh cells, Tfr cells, Treg cells and TTI were all higher in HCC patients than in chronic hepatitis patients and healthy control. TTI was found to have positive correlation with the load of HBV. The AUC of TTI for early HCC and relapse status was better than other clinical indices in HBV positive patients. An optimal cutoff point for the TTI stratified the HCC patients into high (>21.96) and low index (≤21.96) groups. High TTI was significantly correlated with recurrence. Univariate and multivariate analyses revealed TTI could be a predictor for recurrence. Moreover, it retained prognostic performance for patients with lower recurrence risk. Conclusion Our research showed that TTI could be a promising indicator for early recurrence in HCC patients with HBV infection.
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- 2020
25. Unraveling Na and F coupling effects in stabilizing Li, Mn-rich layered oxide cathodes via local ordering modification
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Kim Kisslinger, Jianming Bai, Yan Wang, Steven N. Ehrlich, Panawan Vanaphuti, Feng Wang, and Lu Ma
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Materials science ,Renewable Energy, Sustainability and the Environment ,Diffusion ,Doping ,Oxide ,Energy Engineering and Power Technology ,chemistry.chemical_element ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Redox ,Oxygen ,Cathode ,0104 chemical sciences ,Ion ,law.invention ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,law ,General Materials Science ,Lithium ,0210 nano-technology - Abstract
Regardless of the prevailing capacity and energy density of lithium, manganese-rich layered oxide (LMR-NMC) cathodes, continuous decay of voltage and overall energy density during cycling hinders this material from commercialization in Li-ion batteries. Although significant work focuses on single doping of Na and F, analysis in portraying the benefit of these ions in diminishing the structural distortion during activation cycle is in doubt. Herein, the effects of co-doping Na and F into the LMR-NMC structure in stabilizing the structure and mitigating oxygen loss during the first cycle are closely examined via in situ x-ray measurements. Na and F co-doping shows a 30% lower degree of Li+/Ni2+ mixing in the Li layer (C2/m structure), 50% reduced Debye-Waller factor of Mn-O bonding, increase reversible TM migration, and faster Li diffusion relative to the pristine material. Due to the utilization of Ni redox chemistry below 4.4 V, less oxygen redox is required for charge compensation at high voltage. This study offers the first instance to quantitatively evaluate the effects of co-doping Na and F in LMR-NMC cathode in order to minimize voltage degradation by altering the local ordering of O3-type structure, which may rationalize strategies to overcome the issues of the material.
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- 2020
26. Intracranial Aneurysm Presenting Robust Metal Artifact
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Dingke Wen, Mu Yang, Lingxiao Huang, Xuyang Liu, Chao You, Hao Li, Xinrui Yang, Nicholas W. Kieran, and Lu Ma
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,medicine.medical_treatment ,Ischemia ,Vasospasm ,Magnetic resonance imaging ,Clipping (medicine) ,medicine.disease ,03 medical and health sciences ,Metal Artifact ,0302 clinical medicine ,Aneurysm ,Neuroimaging ,030220 oncology & carcinogenesis ,cardiovascular system ,medicine ,Surgery ,cardiovascular diseases ,Neurology (clinical) ,Radiology ,business ,030217 neurology & neurosurgery ,Craniotomy - Abstract
Background Intracranial aneurysm (IA) is a debilitating cerebrovascular degeneration. Current clinical diagnosis relies mainly on conventional angiogram except for some peculiar aneurysms. Nonetheless, there is no documentation of aneurysm showing robust intracranial artifact on computed tomography or magnetic resonance imaging. Case Description Herein, we report a 45-year-old female with an IA showing a robust intracranial metal artifact. During surgery, the culprit lesion for the artifact was discovered to be hard plaque on the ventral part of the aneurysm. Craniotomy clipping and vessel reconstruction were successful, but minor vasospasm was observed postoperatively. Postoperative pathology and optical emission spectrometer analyses showed elevated iron and copper level in the plaque on the IA. After comparing with other aneurysm samples, we believe the overenriched local iron deposition contributed to the metal artifact on imaging. Conclusions Taken together, accidental findings of intracranial metal artifacts on computed tomography and magnetic resonance imaging can be indicative to iron deposition on intracranial aneurysm. Neuroimaging using magnetic field should be performed with caution. Local accumulation of lysed products from erythrocyte might contribute to the occurrence of this enriched iron deposition, but further evidence regarding the pathogenesis of copper deposition should be provided. Surgically, measures should be taken to avoid perioperative complications like vasospasm and delayed cerebral ischemia. Future report of similar cases would be helpful in optimizing the treatment modality for the aneurysm with metallic plaque.
- Published
- 2020
27. Scalable exfoliation and friction performance of few-layered WS2 nanosheets by microwave-assisted liquid-phase sonication
- Author
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Zan Liu, Lu Ma, and Zhi-Lin Cheng
- Subjects
010302 applied physics ,Ammonium carbonate ,Friction coefficient ,Materials science ,Process Chemistry and Technology ,Sonication ,Liquid phase ,02 engineering and technology ,Tribology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Microwave assisted ,Decomposition ,Exfoliation joint ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,0103 physical sciences ,Materials Chemistry ,Ceramics and Composites ,0210 nano-technology - Abstract
The convenient and high efficient exfoliation for few-layer nanosheets was indispensable for their potential applications. In fact, many reported approaches have been used to successfully exfoliate bulk layered materials into few layers, which fundamentally confronted a few challenges in practice, such as high cost, complicate process, low efficiency and environmental problem. Hence, developing the novel exfoliation process without the above issues was imperative to the prospective application of nanosheets. In this work, we presented a facile and high-quality exfoliation process for few-layer WS2 nanosheets via microwave-assisted sonication method. Detailedly, the crucial highlight in this process was employed the microwave heating expansion via the decomposition of ammonium carbonate pre-impregnated in the interlayers of bulk layered WS2, which was conductive to the second-step liquid phase sonication. The structure characterizations of the as-exfoliated WS2 nanosheets revealed that the high-quality nanosheets had the average lateral size of ca.400 nm and thickness of ca.2.33 nm. Additionally, the tribological performance of the as-exfoliated WS2 nanosheets in oil was investigated, showing that the average friction coefficient of the WS2-based oil was reduced by 28.47% and the wear scar diameter was decreased by 51.67% compared to pristine oil.
- Published
- 2020
28. Enhanced catalytic performance of Zr modified CuO/ZnO/Al2O3 catalyst for methanol and DME synthesis via CO2 hydrogenation
- Author
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Tianpin Wu, Xiao Fan, Weston R. Shoemaker, Naomi Klinghoffer, Zeyu Shang, Shiguang Li, Miao Yu, Lu Ma, Xinhua Liang, and Shoujie Ren
- Subjects
Zirconium ,Materials science ,Process Chemistry and Technology ,chemistry.chemical_element ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Catalysis ,Bifunctional catalyst ,chemistry.chemical_compound ,Crystallinity ,chemistry ,Chemical Engineering (miscellaneous) ,Dimethyl ether ,Methanol ,0210 nano-technology ,Bifunctional ,Waste Management and Disposal ,Nuclear chemistry ,BET theory - Abstract
Zirconium (Zr) modified CuO/ZnO/Al2O3 (CZA) catalysts with different aluminum (Al) and Zr contents were synthesized by the co-precipitation method. The synthesized CuO/ZnO/ZrO2/Al2O3 (CZZA) catalysts were comprehensively characterized and studied for methanol synthesis via CO2 hydrogenation. The CZZA catalyst showed the highest methanol yield of 12.4 % at 220 °C and 2.76 MPa with an optimized catalyst composition of Cu/Zn/Zr/Al (atomic ratio) at 4:2:1:0.5. The CZZA catalyst showed better activity than that of the CZA catalyst and a superior stability for methanol synthesis. There was no decrease in the BET surface area and very little coke formation for the spent CZZA catalyst, after 300 h of methanol synthesis. Bifunctional catalysts, composed of CZZA and HZSM-5, were investigated for dimethyl ether (DME) synthesis directly from CO2 hydrogenation, and a maximum DME yield of 18.3 % was obtained at a reaction temperature of 240 °C and a pressure of 2.76 MPa. The stability of the bifunctional CZZA and HZSM-5 catalyst during the DME synthesis also significantly improved, as compared to that of the CZA and HZSM-5. A significant decrease in the BET surface area and an increase in coking on the spent CZZA catalyst were observed after 100 h of DME synthesis, indicating a detrimental effect on CZZA stability when a HZSM-5 catalyst was present. The changes in structural properties (e.g., BET surface area and crystallinity) and coking for HZSM-5 could be responsible for the deactivation of the bifunctional catalyst.
- Published
- 2020
29. Surface Shape and Tension Distribution of Static Liquids Near Solid Walls in Different Gravity Environment
- Author
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Lu Ma, Min Yu, Shan Chang, Huan Ye, and Xuemin Zhu
- Published
- 2022
30. Household air pollution, adherence to a healthy lifestyle, and risk of cardiometabolic multimorbidity: Results from the China health and retirement longitudinal study
- Author
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Wei, Chen, Xiaoyu, Wang, Jing, Chen, Chao, You, Lu, Ma, Wei, Zhang, and Dong, Li
- Subjects
Retirement ,China ,Environmental Engineering ,Multimorbidity ,Pollution ,Cardiovascular Diseases ,Air Pollution, Indoor ,Air Pollution ,Humans ,Environmental Chemistry ,Longitudinal Studies ,Prospective Studies ,Cooking ,Healthy Lifestyle ,Waste Management and Disposal - Abstract
The adverse health effects of household air pollution have been widely explored, but few studies have evaluated the effects of household air pollution on the risk of cardiometabolic multimorbidity (CMM), a pressing public health concern worldwide. Thus, we aimed to investigate whether exposure to household use of polluting fuels is associated with morbid CMM and, if so, whether a healthy lifestyle could mitigate this association.In this prospective, nationwide representative cohort of the China Health and Retirement Longitudinal Study (CHARLS), participants free of CMM (defined as the coexistence of 2 or more of the following: heart disease, stroke, and diabetes or high blood sugar) were included in 2011-2012 and followed for CMM incidence until 2018. Household air pollution was measured as the use of solid fuels for cooking and heating. The healthy lifestyle score was determined by six factors, physical activity, smoking, body mass index, total cholesterol, blood glucose, and blood pressure, and categorized into three groups (unhealthy, 0-1 factors; intermediate, 2-4; and healthy, 5-6). Cox proportional hazards models investigated associations between household air pollution and incident CMM. The potential modifier effect of a healthy lifestyle score was tested through stratified analyses.Among 7125 eligible participants, 239 incident cases of CMM were identified over a median follow-up of 7.0 years. After adjustment for potential confounders, the use of solid household fuels for heating was associated with more significant hazards of CMM (adjusted hazard ratio [HR] 1.71, 95 % confidence interval [CI] 1.28 to 2.28), while use for cooking (HR, 1.14; 95 % CI, 0.85 to 1.52) was not. Compared with participants in the unhealthy group, those in the healthy and intermediate groups had considerably lower CMM risk, with adjusted HRs (95 % CI) of 0.17 (0.09 to 0.31) and 0.39 (0.29 to 0.53), respectively, regardless of the household air pollution category. Importantly, when participants adhered to a healthy lifestyle, exposure to household air pollution was no longer significantly associated with a higher risk of CMM (adjusted HR 1.77, 95 % CI 0.51 to 6.12; P = 0.369).Household usage of polluting fuels was significantly associated with a higher risk of CMM, and adherence to a healthy lifestyle may mitigate this adverse effect. From a broader perspective, our findings underscore the importance of public health policies and interventions targeting multiple exposures (air pollution, physical activity, smoking, etc.) in enhancing the prevention of detrimental cardiometabolic health effect.
- Published
- 2023
31. Constructing efficient CuO -CeO2 catalyst for NO reduction by CO: New insights into the structure–activity relationship
- Author
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Wei Tan, Yandi Cai, Shaohua Xie, Juntian Xu, Kaili Ma, Kailong Ye, Lu Ma, Steven N. Ehrlich, Weixin Zou, Fei Gao, Lin Dong, and Fudong Liu
- Subjects
General Chemical Engineering ,Environmental Chemistry ,General Chemistry ,Industrial and Manufacturing Engineering - Published
- 2023
32. Experimental study of the formation process and behaviors of spalling in rock materials
- Author
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Jun Xu, Lu Ma, Xiaochun Xiao, and Di Wu
- Subjects
General Engineering ,General Materials Science - Published
- 2023
33. Postnatal delayed growth impacts cognition but rescues programmed impaired pulmonary vascular development in an IUGR rat model
- Author
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Ziming Zhang, Zheng Chen, Xiao-Lu Ma, Li-Zhong Du, Yu Wang, Xuefeng Xu, Xiaofei Luo, LiYan Zhang, Shanshan Xu, Ying Lv, Rahim Ullah, and Lingling Yan
- Subjects
Male ,Litter (animal) ,Endocrinology, Diabetes and Metabolism ,Medicine (miscellaneous) ,Hemodynamics ,Intrauterine growth restriction ,030204 cardiovascular system & hematology ,Weight Gain ,Rats, Sprague-Dawley ,Cognition ,0302 clinical medicine ,Pregnancy ,Enos ,Lactation ,Hippocampus (mythology) ,Fetal Growth Retardation ,Neuronal Plasticity ,Nutrition and Dietetics ,Behavior, Animal ,biology ,Age Factors ,Brain ,medicine.anatomical_structure ,Prenatal Exposure Delayed Effects ,Gestation ,Animal Nutritional Physiological Phenomena ,Female ,Cardiology and Cardiovascular Medicine ,medicine.medical_specialty ,Nitric Oxide Synthase Type III ,Offspring ,Hypertension, Pulmonary ,030209 endocrinology & metabolism ,Pulmonary Artery ,Vascular Remodeling ,03 medical and health sciences ,Internal medicine ,medicine ,Animals ,Cognitive Dysfunction ,Caloric Restriction ,Early Growth Response Protein 1 ,business.industry ,biology.organism_classification ,medicine.disease ,Disease Models, Animal ,Endocrinology ,business ,E1A-Associated p300 Protein - Abstract
Background and aims Intrauterine growth restriction (IUGR) is a state of slower fetal growth usually followed by a catch-up growth. Postnatal catch-up growth in IUGR models increases the incidence of pulmonary arterial hypertension in adulthood. Here, we hypothesize that the adverse pulmonary vascular consequences of IUGR may be improved by slowing down postnatal growth velocity. Meanwhile, cognitive function was also studied. Methods and results We established an IUGR rat model by restricting maternal food throughout gestation. After birth, pups were fed a regular or restricted diet during lactation by changing litter size. Thus, there were three experimental groups according to the dam/offspring diet: C/C (gold standard), IUGR with catch-up growth (R/C) and IUGR with delayed growth (R/D). In adulthood (14 weeks of age), we assessed pulmonary vascular development by hemodynamic measurement and immunohistochemistry. Our results showed that adult R/C offspring developed an elevated mean pulmonary arterial pressure (mPAP) and pulmonary arteriolar remodeling accompanied with decreased eNOS mRNA and protein expressions compared to C/C or R/D offspring. This suggested that delayed postnatal growth improved pulmonary circulation compared to postnatal catch-up growth. Conversely, adult R/D offspring performed poorly in cognition. Behavior test and electrophysiology results exhibited a reduced synaptic plasticity. Furthermore, decreased mRNA expression levels of the memory-related gene zif268 and transcription factor recruitment factor p300 in the hippocampus region were also observed in R/D group. Conclusion These findings indicate that delayed postnatal growth results in cognitive impairment, but it reverses elevations in mPAP induced by postnatal catch-up growth following IUGR.
- Published
- 2019
34. Opportunities and challenges of using big data for global health
- Author
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Youfa Wang, Yaogang Wang, Hongwei Cai, Peng Jia, Lijian Yang, Hong Xue, Shiyong Liu, Therese Hesketh, Xin Liu, Hao Wang, and Lu Ma
- Subjects
Multidisciplinary ,business.industry ,Big data ,Global health ,Business ,Data science - Published
- 2019
35. Structure and reactivity of single site Ti catalysts for propylene epoxidation
- Author
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Zheng Lu, Xiaoyang Liu, Siwen Tang, Lu Ma, Bin Zhang, C. Heath Turner, Tianpin Wu, George J. Nelson, Yong Qin, Zhuoran Gan, and Yu Lei
- Subjects
010405 organic chemistry ,Coordination number ,Inorganic chemistry ,Oxide ,chemistry.chemical_element ,010402 general chemistry ,01 natural sciences ,Catalysis ,0104 chemical sciences ,law.invention ,chemistry.chemical_compound ,chemistry ,law ,Calcination ,Reactivity (chemistry) ,Propylene oxide ,Physical and Theoretical Chemistry ,Selectivity ,Titanium - Abstract
Propylene epoxidation using molecular oxygen and hydrogen mixture on Au-based catalysts has attracted attention because of high propylene oxide selectivity and the use of an inexpensive and environmental friendly oxidant. Single-site titanium on metal oxide supports plays an important role in achieving high reactivity and selectivity in propylene epoxidation. Here we used TiO2 atomic layer deposition (ALD) to synthesize single-site titanium imbedded in the SiO2 framework for propylene epoxidation. High temperature calcination was used as post-treatment to control the titania structure and Ti O coordination number. Using UV–vis spectroscopy and X-ray absorption spectroscopy, we successfully established that under similar propylene conversion the selectivity to propylene oxide (PO) is strongly correlated to the Ti O coordination number and bond length. Using a cluster model, density functional theory (DFT) calculations indicate that the partial charges of single Ti SiO2 sites scale linearly as a function of the coordination number. Also, the predicted Ti O bond lengths follow the same trend as found in the experiments, providing additional support for the observed experimental activity relationships.
- Published
- 2019
36. Platelet activation status in the diagnosis and postoperative prognosis of hepatocellular carcinoma
- Author
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Baishen Pan, Xiao-Lu Ma, Shuang-Jian Qiu, Xin-Rong Yang, Wei Guo, Jie Zhu, Yun-Feng Cheng, Jian Zhou, Hao Wang, Jia Fan, and Beili Wang
- Subjects
Male ,0301 basic medicine ,medicine.medical_specialty ,Carcinoma, Hepatocellular ,Clinical Biochemistry ,Biochemistry ,Gastroenterology ,03 medical and health sciences ,0302 clinical medicine ,Recurrence ,Internal medicine ,medicine ,Humans ,Platelet ,Postoperative Period ,Platelet activation ,Neoplasm Metastasis ,Risk factor ,Prospective cohort study ,Univariate analysis ,Receiver operating characteristic ,Proportional hazards model ,business.industry ,Liver Neoplasms ,Biochemistry (medical) ,General Medicine ,Middle Aged ,Platelet Activation ,Prognosis ,medicine.disease ,030104 developmental biology ,030220 oncology & carcinogenesis ,Hepatocellular carcinoma ,Female ,business ,Biomarkers - Abstract
Background The venous thromboembolism, which may be caused by increased platelet activation, is a risk factor for tumor prognosis. We determined the platelet activation status for diagnosis and predicting postoperative prognosis of hepatocellular carcinoma. Methods We conducted a prospective study of 191 patients diagnosed with HCC at Zhongshan Hospital from April 2016 to July 2016 as well as 99 healthy people. The platelet activation status was assessed by 2 platelet markers, PAC-1 and CD62p, using flow cytometry. The patients were treated with TACE or resection and monitored for ≥6 months. The diagnostic value of marker-positive platelets was determined by the receiver operating characteristic curve and the postoperative value were analyzed using the Kaplan-Meier method and COX regression model. Results All the 3 groups with high levels of marker-positive platelets were likely to be diagnosed with HCC and the PAC-1+ percentage had the best efficacy. The univariate analysis showed that the levels of PAC-1+ and CD62p+ platelets was risker factors for poor postoperative prognosis after both TACE and resection. Moreover, the multivariate analysis revealed that the level of PAC-1+ platelets was an independent risk factor for poor prognosis. Conclusions The PAC-1+ percentage of platelets is a new indicator for diagnosis and predicting postoperative prognosis.
- Published
- 2019
37. Crocin attenuation of neurological deficits in a mouse model of intracerebral hemorrhage
- Author
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Youping Li, Lu Ma, Chao You, Xin Qi, Yang Wei, Meng Tian, Xi Guo, Zhongxin Duan, Dayong Wu, and Hao Li
- Subjects
Male ,0301 basic medicine ,medicine.medical_treatment ,Brain Edema ,Pharmacology ,Antioxidants ,Crocin ,Mice ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Oral administration ,medicine ,Animals ,Collagenases ,cardiovascular diseases ,Saline ,Cerebral Hemorrhage ,Intracerebral hemorrhage ,chemistry.chemical_classification ,Reactive oxygen species ,business.industry ,General Neuroscience ,Brain ,Histology ,medicine.disease ,Carotenoids ,nervous system diseases ,Mice, Inbred C57BL ,Stroke ,Heme oxygenase ,Disease Models, Animal ,030104 developmental biology ,chemistry ,Nerve Degeneration ,Immunohistochemistry ,Nervous System Diseases ,Reactive Oxygen Species ,business ,Heme Oxygenase-1 ,030217 neurology & neurosurgery - Abstract
Intracerebral hemorrhage (ICH) is a devastating subtype of stroke that is associated with high morbidity and mortality. However, up to now, there are no effective prevention methods or specific therapies to improve its clinical outcomes. Herein, we explore preliminarily the efficacy of crocin, a carotenoid extracted from the stigma of saffron known for its anti-oxidation and free radical scavenging activities, in a mouse ICH model induced with collagenase infusion. Crocin or saline was administrated 6 h after ICH and then every 12 h for up to 7 days. Neurological scores were examined on days 1, 3, and 7 after ICH. Mice were sacrificed after1, 3, and 7 days of crocin treatment for examination of histology and immunohistochemistry. The results showed that oral administration of crocin attenuated the neurological deficits and reduced the myelin loss, neuron degeneration, iron deposition, reactive oxygen species (ROS) production and heme oxygenase-1 (HO-1) expression in the early stage of ICH, making it potential to be an ideal candidate for medical therapy of ICH in clinic.
- Published
- 2019
38. Deferoxamine Alleviates Iron Overload and Brain Injury in a Rat Model of Brainstem Hemorrhage
- Author
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Xi Guo, Xin Qi, Meng Tian, Chao You, Fan Zhang, Lu Ma, Yang Wei, Zhongxin Duan, and Hao Li
- Subjects
Male ,Iron Overload ,medicine.medical_treatment ,Deferoxamine ,Pharmacology ,Rats, Sprague-Dawley ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Animals ,Collagenases ,Saline ,Survival rate ,Myelin Sheath ,Survival analysis ,Chelating Agents ,Intracerebral hemorrhage ,business.industry ,Therapeutic effect ,medicine.disease ,Immunohistochemistry ,Survival Analysis ,Rats ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Nerve Degeneration ,Brain Stem Hemorrhage, Traumatic ,Surgery ,Neurology (clinical) ,Neuron ,Nervous System Diseases ,Reactive Oxygen Species ,business ,Heme Oxygenase-1 ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Background Brainstem hemorrhage (BSH) is the most dangerous and devastating subtype of intracerebral hemorrhage and is associated with high morbidity and mortality. However, to date, no effective prevention methods or specific therapies have been available to improve its clinical outcomes. We preliminarily explored the efficacy of deferoxamine (DFO), a clinical chelator known for its iron-scavenging activities, in a rat model of BSH induced with collagenase infusion. Methods DFO or saline was administrated 6 hours after BSH induction and then every 12 hours for ≤7 days. The survival curve of the rats was created, and the neurological scores were examined on days 1, 3, and 7 after BSH. The rats were sacrificed after 1, 3, and 7 days of DFO treatment for histological examination and immunohistochemistry. Results The results showed that administration of DFO delayed erythrocytes lysis, reduced iron deposition, reduced reactive oxygen species generation, reduced heme oxygenase-1 expression, and alleviated brain injury such as neuron degeneration and myelin sheath injury. However, DFO did not improve the survival rate and neurobehavioral outcomes in this model. Conclusions Administration of DFO had limited therapeutic effects on collagenase-induced brainstem hemorrhage in rats. Some potential explanations were proposed, and more preclinical work is required to clarify the controversial curative effect of DFO in ICH.
- Published
- 2019
39. Predictive Accuracy of Alpha-Delta Ratio on Quantitative Electroencephalography for Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage: Meta-Analysis
- Author
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Dingke Wen, Jun Zheng, Zhiyuan Yu, Rui Guo, Chao You, Lu Ma, and Hao Li
- Subjects
medicine.medical_specialty ,Funnel plot ,Subarachnoid hemorrhage ,Electroencephalography ,Brain Ischemia ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,cardiovascular diseases ,medicine.diagnostic_test ,Receiver operating characteristic ,business.industry ,Publication bias ,Subarachnoid Hemorrhage ,medicine.disease ,Quantitative electroencephalography ,Confidence interval ,030220 oncology & carcinogenesis ,Meta-analysis ,Cardiology ,Surgery ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
Objective Delayed cerebral ischemia (DCI) is significantly related to death and unfavorable functional outcome in patients with aneurysmal subarachnoid hemorrhage (SAH). The association between alpha-delta ratio (ADR) on quantitative electroencephalography (EEG) and DCI has been reported in several previous studies, but their results are conflicting. This meta-analysis was conducted to assess the accuracy of ADR for DCI prediction in patients with aneurysmal SAH. Methods PubMed and Embase were systematically searched for related records. Study selection and data collection were completed by 2 investigators. Sensitivity, specificity, and their 95% confidence intervals (CIs) were pooled. A summary receiver operating characteristic curve was plotted to show the pooled accuracy. Deeks funnel plot was used to evaluate publication bias. Results Five studies were included in this meta-analysis. The pooled sensitivity and specificity of worsening ADR for DCI prediction in patients with aneurysmal SAH were 0.83 (95% CI 0.44–0.97) and 0.74 (95% CI 0.50–0.89), respectively. In addition, the area under the summary receiver operating characteristic curve was 0.84 (95% CI 0.81–0.87). No obvious publication bias was found using Deeks funnel plot (P = 0.29). Conclusions Worsening ADR on quantitative EEG is a reliable predictor of DCI in patients with aneurysmal SAH. Further studies are still needed to confirm the role of quantitative EEG in DCI prediction.
- Published
- 2019
40. Fabrication and photocatalytic performance of C, N, F-tridoped TiO2 nanotubes
- Author
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Ping Wang, Gui Chang Wang, Wei Ping Huang, Lu Lu Ma, Bao Lin Zhu, Dan Guo, Shou Min Zhang, Lili Wang, and Xue Wang
- Subjects
Anatase ,Materials science ,Dopant ,Band gap ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Catalysis ,0104 chemical sciences ,law.invention ,chemistry.chemical_compound ,X-ray photoelectron spectroscopy ,chemistry ,law ,Methyl orange ,Photocatalysis ,Calcination ,0210 nano-technology ,Nuclear chemistry - Abstract
By impregnating the thermal stable TiO2 nanotubes (C/TiO2NTs) in NH4F solution with different concentrations and subsequent calcination treatment at different temperatures, C, N, F-tridoped TiO2 nanotubes (C, N, F/TiO2NTs) were prepared. XRD, XPS, TEM, TG-DTG, UV–vis and nitrogen adsorption were used to and characterize the prepared materials. The influences of dopants, calcination temperature and NH4F concentration on the catalytic performances of C, N, F/TiO2NTs under UV light and simulated sunlight were investigated by using methyl orange solution as simulant wastewater. Obtained results indicated that the C, N, F/TiO2NTs exhibited higher photocatalytic activity than the C-doped or N, F-codoped ones, and the C, N, F/TiO2NTs showed the best photocatalytic performance when they were calcinated at 300 °C and impregnated by 1 wt.% NH4F solution. The electronic density of states (DOS) analysis results implied that the C, N, F-tridoping could improve the electronic transition and narrow the band gap of anatase TiO2, and resulted in improved photocatalytic performance. The synergistic effects of the three dopants were also discussed.
- Published
- 2019
41. Comparison of Acute Moyamoya Disease−Related and Idiopathic Primary Intraventricular Hemorrhage in Adult Patients
- Author
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Zhiyuan Yu, Dingke Wen, Mou Li, Hao Li, Rui Guo, Lu Ma, Jun Zheng, and Chao You
- Subjects
Male ,Pediatrics ,medicine.medical_specialty ,Younger age ,Lower blood pressure ,Renal function ,Blood Pressure ,Kidney ,03 medical and health sciences ,0302 clinical medicine ,Statistical analyses ,Humans ,Medicine ,Moyamoya disease ,Aged ,Cerebral Intraventricular Hemorrhage ,Retrospective Studies ,Adult patients ,business.industry ,Angiography, Digital Subtraction ,Middle Aged ,medicine.disease ,Treatment Outcome ,Intraventricular hemorrhage ,030220 oncology & carcinogenesis ,Baseline characteristics ,Acute Disease ,Female ,Surgery ,Neurology (clinical) ,Moyamoya Disease ,Tomography, X-Ray Computed ,business ,030217 neurology & neurosurgery - Abstract
Primary intraventricular hemorrhage (PIVH) is a rare condition in adult patients. PIVH occurs frequently in adult hemorrhagic Moyamoya disease (MMD). Idiopathic PIVH is defined as PIVH without cerebrovascular abnormalities. This study is aimed to compare the baseline characteristics and outcomes of acute MMD-related and idiopathic PIVH.Adult patients with acute MMD-related or idiopathic PIVH were retrospectively included. Baseline characteristics and outcomes at discharge were obtained and compared. Chi-square test, Student's t-test, or rank-sum test were used in statistical analyses.This study finally included 32 patients with acute MMD-related PIVH and 112 with acute idiopathic PIVH. Patients with acute MMD-related PIVH were significantly younger (53.3 ± 15.8 vs. 42.8 ± 12.2 years, P0.001). The admission systolic blood pressure in patients with acute idiopathic PIVH was significantly higher (161.7 ± 30.9 vs. 134.6 ± 24.6 mm Hg, P0.001). Patients with acute idiopathic PIVH had significantly higher admission serum urea (5.68 ± 2.66 vs. 4.34 ± 1.62 mmol/L, P = 0.008), cystatin C (0.97 ± 0.72 vs. 0.68 ± 0.16 mg/L, P = 0.023), and uric acid (309.01 ± 105.97 vs. 242.24 ± 77.65 μmol/L, P = 0.001). In patients with acute MMD-related PIVH, only one (3.1%) patient was dead at discharge. In contrast, a total of 22 (19.6%) patients with acute idiopathic patients died at discharge (P = 0.027).Compared with patients with acute idiopathic PIVH, patients with acute MMD-related PIVH have younger age, lower blood pressure, and better renal function. Moreover, patients with acute MMD-related PIVH have lower short-term mortality.
- Published
- 2019
42. Accuracy of swirl sign for predicting hematoma enlargement in intracerebral hemorrhage: a meta-analysis
- Author
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Lu Ma, Jun Zheng, Maiyue He, Hao Li, Rui Guo, Chao You, and Zhiyuan Yu
- Subjects
Male ,medicine.medical_specialty ,Poor prognosis ,Sensitivity and Specificity ,Likelihood ratios in diagnostic testing ,03 medical and health sciences ,0302 clinical medicine ,Hematoma ,medicine ,Humans ,In patient ,030212 general & internal medicine ,Cerebral Hemorrhage ,Intracerebral hemorrhage ,business.industry ,Brain ,Prognosis ,medicine.disease ,Neurology ,Meta-analysis ,Female ,Neurology (clinical) ,Radiology ,Tomography, X-Ray Computed ,business ,030217 neurology & neurosurgery ,Sign (mathematics) - Abstract
Background Hematoma enlargement happens in about 30% patients with intracerebral hemorrhage, which is reported to be closely correlated with poor prognosis. Swirl sign has been reported to have correlation with hematoma enlargement. This meta-analysis analyzed the accuracy of swirl sign for predicting hematoma enlargement in intracerebral hemorrhage. Methods Five databases were searched for potentially eligible literature. Studies were included if they were about the predictive properties of swirl sign for hematoma enlargement in intracerebral hemorrhage. Sensitivity and specificity of swirl sign for hematoma enlargement prediction were pooled. Pooled positive and negative likelihood ratios were also calculated. Results Six studies with 2647 patients were finally included in meta-analysis. The pooled sensitivity and specificity of swirl sign were 0.45 (95%CI 0.32–0.59) and 0.79 (95%CI 0.73–0.84), respectively. The pooled positive likelihood ratio of swirl sign was 2.2 (95%CI 1.8–2.5). In contrast, the pooled negative likelihood ratio of swirl sign was 0.69 (95%CI 0.57–0.84). Conclusions This meta-analysis suggests that swirl sign has the relatively high specificity for hematoma enlargement prediction in patients with intracerebral hemorrhage.
- Published
- 2019
43. Palladium nanocrystals-imbedded mesoporous hollow carbon spheres with enhanced electrochemical kinetics for high performance lithium sulfur batteries
- Author
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Geping Yin, Yang Wang, Pengjian Zuo, Mengxue He, Han Zhang, Liguang Wang, Tianpin Wu, Shaobo Ma, and Lu Ma
- Subjects
Materials science ,Electrochemical kinetics ,chemistry.chemical_element ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrocatalyst ,01 natural sciences ,Sulfur ,0104 chemical sciences ,Catalysis ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,Chemisorption ,General Materials Science ,Lithium ,0210 nano-technology ,Polysulfide ,Palladium - Abstract
Lithium sulfur (Li-S) battery is one promising candidate for high energy density electrochemical energy storage system. Accelerating the sluggish reaction kinetics of sulfur cathode and suppressing the lithium polysulfide (LiPS) shuttle are crucial for the high-performance Li-S batteries. Herein, we prepared the catalytic palladium nano-particles (Pd NPs) imbedded in hollow carbon spheres (Pd@HCS) as sulfur host by a sacrificial template method. Benefitting from the hollow nanostructure and strong chemisorption ability of Pd NPs, Pd@HCS can effectively mitigate the LiPS shuttling via physical and chemical pathways. Furthermore, the Pd NPs as one electrocatalyst can accelerate the redox reaction kinetics of LiPS. The theoretical calculation and X-ray absorption spectroscopy elucidate that the moderate Pd-S bonding between Pd NPs and sulfur species are beneficial to LiPS conversion. The Pd@HCS/S electrode delivers a high initial capacity of 1306 mAh g−1 and 885 mAh g−1 after 100 cycles at 0.2 C, as well as the good cycling stability (a slight capacity decay of 0.068% per cycle over 400 cycles at 1 C). The Pd@HCS/S cathode with the high sulfur loading of 5.88 mg cm−2 delivers an initial capacity of 873 mAh g−1 at 0.2 C and good capacity retention of 85% after 100 cycles.
- Published
- 2019
44. Impact of weather conditions on middle school students’ commute mode choices: Empirical findings from Beijing, China
- Author
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Zhong Wang, Hui Xiong, Kaiqiang Xie, and Lu Ma
- Subjects
050210 logistics & transportation ,Car ownership ,business.industry ,020209 energy ,05 social sciences ,Mode (statistics) ,Poison control ,Transportation ,02 engineering and technology ,Beijing ,Public transport ,0502 economics and business ,0202 electrical engineering, electronic engineering, information engineering ,Economics ,Econometrics ,Multinomial probit ,business ,Air quality index ,General Environmental Science ,Civil and Structural Engineering ,Multinomial logistic regression - Abstract
Weather conditions have been recognized as important factors affecting school commute mode choices. This paper aims to explore the modal shift of middle school commutes with respect to the variation in weather-related variables, with empirical emphases on the situation in Beijing, China. Data from the latest Beijing School Commute Survey (2014–2015) were adopted, and multinomial probit (MNP) and multinomial logit (MNL) models were developed. The modeling results are in favor of the MNP model because it has better statistical performance. Weather-related variables, including sky condition, wind speed, highest temperature, humidity, air quality index (AQI), and some interaction terms, were found to have a significant impact on students' commute mode choices. Based on these models, an empirical sensitivity measure was defined as the expected percentage change in the probability of choosing each mode with respect to an order of magnitude change in the influential factors. Most of the results are in line with those of previous studies, and some unique results reflect features of Beijing. For example, on days with extremely poor air quality, students are more likely to turn to public transport rather than use a car from active transportation modes. This is probably due to the special urban traffic regulations that restrict household car ownership and car travel in Beijing. These findings could have implications for promoting active transportation for students and serve as references for policymakers and planners.
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- 2019
45. Density and viscosity of aqueous blend of 1-butyl-3-methylimidazolium tetrafluoroburate ([Bmim][BF4]) + piperazine (PZ) and its performance of CO2 absorption
- Author
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Jiu-Yang Wang, Hong-Lu Ma, Jian-Gang Lu, Xin Zhao, Xu Zhengwen, Shao Ying, and Xiang Li
- Subjects
Aqueous solution ,Materials science ,Atmospheric pressure ,Analytical chemistry ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Mole fraction ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,Viscosity ,Piperazine ,chemistry.chemical_compound ,chemistry ,Co2 absorption ,Materials Chemistry ,Physical and Theoretical Chemistry ,0210 nano-technology ,Mass fraction ,1-butyl-3-methylimidazolium ,Spectroscopy - Abstract
An aqueous blend of 1-butyl-3-methylimidazolium tetrafluoroburate ([Bmim][BF4]) + piperazine (PZ) was proposed in this work. Density and viscosity of the aqueous blend were measured and correlated at (293.15–333.15) K and atmospheric pressure. Performance of CO2 absorption into the aqueous blend was evaluated. It turned out that PZ mass fraction slightly influenced on the density and viscosity, being linear with them. Temperature significantly affected the viscosity. The calculated values are in good agreement with the experimental values. The main factors affecting the CO2 loading of the aqueous blend were PZ mass fraction, gas CO2 mole fraction and temperature. The average absorption rate of the aqueous blend was the biggest in the aqueous [Bmim][BF4], PZ and [Bmim][BF4]/PZ, and much higher than that of the former two. The performance of the aqueous [Bmim][BF4]/PZ with low PZ mass fraction was better than that with high PZ mass fraction. It demonstrated that the aqueous blend of [Bmim][BF4]/PZ is a good absorbent of CO2.
- Published
- 2019
46. Interactions of oligochitosan with blood components
- Author
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Tong Sun, Hong Tan, Hao Li, Meng Tian, Xi Guo, Lu Ma, Rui Zhong, Junwen Guan, Chao You, and Zhipeng Gu
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Blood Platelets ,Erythrocytes ,Platelet Aggregation ,Oligosaccharides ,Chitin ,02 engineering and technology ,Hemolysis ,Biochemistry ,03 medical and health sciences ,chemistry.chemical_compound ,Structural Biology ,Coagulation testing ,medicine ,Humans ,Platelet ,Platelet activation ,Hydrogen peroxide ,Blood Coagulation ,Complement Activation ,Molecular Biology ,030304 developmental biology ,Chitosan ,0303 health sciences ,Ethanol ,Complement System Proteins ,Hydrogen Peroxide ,General Medicine ,Carbon-13 NMR ,Platelet Activation ,021001 nanoscience & nanotechnology ,medicine.disease ,chemistry ,Coagulation system ,Biophysics ,0210 nano-technology - Abstract
Oligochitosan (OCHI) is known to have some specific biological activities. However, its interactions with blood components and related correlation with molecular structures remains to be clarified due to its growing use in biomedical areas. Herein, a series of OCHI were prepared by hydrogen peroxide induced degradation combined fractionation in ethanol solutions and their molecular structures were characterized by GPC, FTIR, 1H and 13C NMR, and then the interactions of the prepared OCHI with blood components, including red blood cells (hemolysis, deformability, and aggregation), coagulation system, complement (C3a, and C5a activation), and platelet (activation, and aggregation), were investigated. For red blood cells, OCHI has a quite low risk of hemolysis in a dose- and MW-dependent manner and the deformability and aggregation were observed in its high MW fraction. The coagulation tests revealed that OCHI is capable of a mild anticoagulation through blocking the intrinsic pathway and the anticoagulation corresponding MW was identified. In terms of complement, OCHI could inhibit C3a in a dose-dependent manner and activate C5a with its high MW fraction. In addition, there is no significant effect of OCHI on platelet activation and aggregation. Based on above results, the interactions related mechanism was discussed and proposed.
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- 2019
47. Smooth associations between the emergency medical services response time and the risk of death in road traffic crashes
- Author
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Ziqi Song, Xuedong Yan, Lu Ma, Jiangfeng Wang, Hui Xiong, and Hao Zhang
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business.industry ,Health Policy ,Public Health, Environmental and Occupational Health ,Fatality Analysis Reporting System ,Human factors and ergonomics ,Poison control ,Transportation ,Logistic regression ,Pollution ,Occupational safety and health ,Odds ,Injury prevention ,Emergency medical services ,Medicine ,Safety, Risk, Reliability and Quality ,business ,Safety Research ,Demography - Abstract
Background Understanding the impact of emergency medical services (EMS) response times on the likelihood of death has received repeated attention in the literature. However, the current literature lacks definite and detailed results. This study seeks to contribute by revealing a smoothed conditional association between EMS response times and the odds of fatality, also allowing this association to be heterogeneous with respect to the statuses of other influential variables. Methods The 2015 Fatality Analysis Reporting System (FARS) national dataset of the United States was adopted as it was large enough to support the sample-size requirement for exhibiting heterogeneous smooth link functions of EMS response times, with higher confidence levels. An additive logistic regression model with smooth interaction terms was introduced. Two ordinary logistic models with different settings for the EMS response time were developed for comparison with the additive logistic model. Results The overall impact of the EMS response time, as well as age, gender, seating position and manner of collision, on the odds of death, was statistically significant. For the first time, the marginal smooth influential pattern of the EMS response time was found to be non-monotonic, such that, for cases with long EMS response times, it could be negatively associated with the odds of death. Similar phenomena were also found when the EMS response time interacted with several other factors. Conclusion Two critical values (5.5 minutes and 17 minutes respectively) of the EMS response time were found. The former represents the fastest decline in the chance of survival and the latter is just the “gold time” for operating rescues. Overestimation of the urgency level of certain types of crashes at the very early stages of rescues could be the main reason for observing a negative influential pattern of the EMS response time on the odds of death.
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- 2019
48. Enhanced lithium storage capability of FeF3·0.33H2O single crystal with active insertion site exposed
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Zhaohua Wang, Junping Hu, Feng Wu, Jun Lu, Yu Li, Mizi Chen, Yifei Yuan, Chuan Wu, Ying Bai, Xingzhen Zhou, Lu Ma, Guoqiang Tan, and Guanghai Chen
- Subjects
Battery (electricity) ,Materials science ,Renewable Energy, Sustainability and the Environment ,Intercalation (chemistry) ,chemistry.chemical_element ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Electrochemistry ,01 natural sciences ,Cathode ,0104 chemical sciences ,law.invention ,chemistry ,Chemical engineering ,law ,Nano ,Ionic conductivity ,General Materials Science ,Lithium ,Electrical and Electronic Engineering ,0210 nano-technology ,Single crystal - Abstract
Iron fluoride cathode for lithium batteries intrigues researchers for decades due to high capacity and low cost, but suffers from poor electronic and ionic conductivity. Hierarchical micro/nano construction with preferred orientation growth can shorten ion diffusion pathway and facilitate electron transportation without inducing side reactions. Here, FeF3·0.33H2O hierarchical microspheres self-assembled by octagonal single crystal slices are prepared. Benefiting from the artful structure, SAED and XRD characterizations confirm that the octagonal single crystal slices provides more lithium ions intercalation positions (4c sites). Electrochemical tests demonstrate that the well designed FeF3·0.33H2O single crystal (FFH-S) delivers 30 mAh g−1 higher capacity (172 mAh g−1 at 0.1C) than the common FeF3·0.33H2O polycrystal (FFH-P). In-situ XRD combined with theoretic calculation elucidate the difference in lithium storage capacity. Instructive argument that single crystal octagon slices with [110] oriented growth provide more active sites for lithium ions intercalation contributes to the preparation of high performance iron fluoride cathode materials for rechargeable battery.
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- 2019
49. Determining the Optimal Shape-Related Indicator on Noncontrast Computed Tomography for Predicting Hematoma Expansion in Spontaneous Intracerebral Hemorrhage
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Mou Li, Jun Zheng, Lu Ma, Rui Guo, Chao You, Zhiyuan Yu, Xiaoze Wang, and Hao Li
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Adult ,Male ,medicine.medical_specialty ,Time Factors ,Tomography Scanners, X-Ray Computed ,Irregular shape ,Computed tomography ,Logistic regression ,Independent predictor ,03 medical and health sciences ,0302 clinical medicine ,Hematoma ,medicine ,Humans ,Spontaneous intracerebral hemorrhage ,Aged ,Cerebral Hemorrhage ,Retrospective Studies ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Brain ,Retrospective cohort study ,Middle Aged ,medicine.disease ,ROC Curve ,030220 oncology & carcinogenesis ,Multivariate Analysis ,Female ,Surgery ,Neurology (clinical) ,Radiology ,business ,030217 neurology & neurosurgery ,Sign (mathematics) - Abstract
Objective Among several novel predictors on noncontrast computed tomography (CT) for hematoma expansion in spontaneous intracerebral hemorrhage (sICH), shape irregularity grade, satellite sign, and island sign are all related to irregular shape of hematoma. This study is aimed to compare the accuracy of these imaging markers for predicting hematoma expansion in the same cohort of sICH patients. Methods This retrospective study enrolled sICH patients who underwent diagnostic computed tomography (CT) scans within 6 hours after onset and another follow-up CT scan within 24 hours after initial CT scan. Shape irregularity grade, satellite sign, and island sign were assessed according to the definitions in previous studies. The accuracy of these imaging indicators for predicting hematoma expansion was analyzed using receiver operator analysis. Results Finally, a total of 196 patients were included. Shape irregularity grade ≥3 was found in 87 (44.39%) patients, satellite sign was identified in 76 (38.78%) patients, and island sign was shown in only 41 (20.92%) patients. Only island sign remained an independent predictor for hematoma expansion in multivariate logistic regression. The sensitivity values of shape irregularity grade ≥3, satellite sign, and island sign were 0.52, 0.63, and 0.48, respectively. By contrast, the specificity values of these 3 predictors were 0.58, 0.69, and 0.85, respectively. Shape irregularity grade ≥3 had the smallest area under the curve (0.597), and island sign had the largest (0.676). Conclusions Island sign seems to be the optimal shape-related predictor for hematoma expansion in sICH patients and could be included in the future predictive model for hematoma expansion.
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- 2019
50. BAMBI shuttling between cytosol and membrane is required for skeletal muscle development and regeneration
- Author
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Taiyong Yu, Xiaohan Pan, Guohuan Xu, Huabing Zhang, Yanting Xu, Gongshe Yang, Yulong Yin, Shujie Chen, Xiaoshuang Dai, Liwei Xie, Mulan Han, Xiangping Yao, Fengxue Xi, and Lu Ma
- Subjects
Male ,0301 basic medicine ,Biophysics ,Muscle Development ,Bone morphogenetic protein ,Biochemistry ,Muscle hypertrophy ,03 medical and health sciences ,Cytosol ,0302 clinical medicine ,medicine ,Animals ,Regeneration ,Myocyte ,Muscle, Skeletal ,Molecular Biology ,Chemistry ,Regeneration (biology) ,Cell Membrane ,Wnt signaling pathway ,Membrane Proteins ,Skeletal muscle ,Cell Biology ,Cell biology ,Mice, Inbred C57BL ,Protein Transport ,030104 developmental biology ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,BAMBI ,C2C12 - Abstract
Bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) gene encodes a transmembrane protein and is involved in multiple physiological and pathological processes, such as inflammatory response, tumor development and progression, cell proliferation and differentiation. A previous study suggested that BAMBI may interact with the Wnt/β-catenin signaling pathway via promoting β-catenin nuclear translocation associated with C2C12 myogenic myoblast differentiation. However, its biological function in skeletal muscle still remains unknown and requires further characterization. The present work sought to investigate its biological function in skeletal muscle, especially the physiological roles of BAMBI during skeletal muscle growth and regeneration. Our current work suggests that BAMBI protein is highly expressed in skeletal muscle and is only detected in cytosolic fraction in the resting muscle. Moreover, BAMBI protein is co-localized in fast-twitch (glycolytic) fibers, but not in slow-twitch (oxidative) fibers. Comparing with the cytosolic trapping in resting muscle, BAMBI protein is enriched on cellular membrane during the muscle growth and regeneration, suggesting that BAMBI-mediated a significant signaling pathway may be an essential part of muscle growth and regeneration.
- Published
- 2019
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