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Adaptive mesh methods are reliable and efficient approaches in hydrological and hydraulic modelling. In some cases, however, big challenges are faced when constructing the adaptive meshes that not only have a good quality but also maintain the integrity of the geological structures. In this paper, a local refinement technique using Delaunay triangulation method is developed for these purposes. Specific treatments are proposed to deal with the soil interfaces and boundaries usually encountered in geological structures. The application and quantitative evaluation show that a satisfactory result has been obtained for a complicated geological slope.

Eight rhesus macaques inoculated with molecularly cloned SIV mac 239 developed viremia and virus-binding antibod-ies, but only one (macaque 2D) developed neutralizing antibodies to the virus. Viremia persisted in macaque 2D even in the presence of neutralizing antibodies. Neutralizing antibodies in the plasma collected from macaque 2D late in infection neutralized virus isolated early in infection. In contrast, these antibodies failed to neutralize the plasma viruses isolated after the appearance of neutralizing antibodies. Only antigenic variants were isolated from blood, spleen, and lymph nodes. Viruses isolated from other macaques that did not develop neutralizing antibodies were neutralized by 2D serum and were of the parental (SIV mac 239) phenotype. The variant viruses maintained their strict tropism for lymphocytes, similar to the parental virus.