85 results on '"Maes, Louis"'
Search Results
2. 3-nitroimidazo[1,2-b]pyridazine as a novel scaffold for antiparasitics with sub-nanomolar anti-Giardia lamblia activity
3. Nucleoside analogues for the treatment of animal trypanosomiasis
4. Exploration of 6-methyl-7-(Hetero)Aryl-7-Deazapurine ribonucleosides as antileishmanial agents
5. N-modification of 7-Deazapurine nucleoside analogues as Anti-Trypanosoma cruzi and anti-Leishmania agents: Structure-activity relationship exploration and In vivo evaluation
6. 6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents
7. Synthesis and evaluation of 3′-fluorinated 7-deazapurine nucleosides as antikinetoplastid agents
8. Bioassay-guided isolation of antiplasmodial and antimicrobial constituents from the roots of Terminalia albida
9. Synthesis and evaluation of a collection of purine-like C-nucleosides as antikinetoplastid agents
10. Heteroaryl ether analogues of an antileishmanial 7-substituted 2-nitroimidazooxazine lead afford attenuated hERG risk: In vitro and in vivo appraisal
11. Antimicrobial investigation of ethnobotanically selected guinean plant species
12. Sand Fly Studies Predict Transmission Potential of Drug-resistant Leishmania
13. Impact of clinically acquired miltefosine resistance by Leishmania infantum on mouse and sand fly infection
14. Comparative evaluation of nucleic acid stabilizing reagents for RNA- and DNA-based Leishmania detection in blood as proxy for visceral burdens
15. C6–O-alkylated 7-deazainosine nucleoside analogues: Discovery of potent and selective anti-sleeping sickness agents
16. Structure-activity relationship of 4-azaindole-2-piperidine derivatives as agents against Trypanosoma cruzi
17. Impaired development of a miltefosine-resistant Leishmania infantum strain in the sand fly vectors Phlebotomus perniciosus and Lutzomyia longipalpis
18. The synthesis and in vitro biological evaluation of novel fluorinated tetrahydrobenzo[j]phenanthridine-7,12-diones against Mycobacterium tuberculosis
19. In vitro and in vivo antiplasmodial activity of extracts and isolated constituents of Alstonia congensis root bark
20. Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2)
21. Characterization of the role of N-glycosylation sites in the respiratory syncytial virus fusion protein in virus replication, syncytium formation and antigenicity
22. Double prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents
23. Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity
24. Amino acid based prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents
25. Revisiting tubercidin against kinetoplastid parasites: Aromatic substitutions at position 7 improve activity and reduce toxicity
26. Synthesis and antimicrobial activities of N6-hydroxyagelasine analogs and revision of the structure of ageloximes
27. Optimization of the pharmacokinetic properties of potent anti-trypanosomal triazine derivatives
28. Evaluation of a Pan-Leishmania Spliced-Leader RNA Detection Method in Human Blood and Experimentally Infected Syrian Golden Hamsters
29. UPLC/MS MS data of testosterone metabolites in human and zebrafish liver microsomes and whole zebrafish larval microsomes
30. Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides
31. Novel triazine dimers with potent antitrypanosomal activity
32. Optimization and characterization of a murine lung infection model for the evaluation of novel therapeutics against Burkholderia cenocepacia
33. In vitro CYP-mediated drug metabolism in the zebrafish (embryo) using human reference compounds
34. Comparative analysis of the internalization of the macrophage receptor sialoadhesin in human and mouse primary macrophages and cell lines
35. 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]thiazoles: Facile synthesis and comparative appraisal against tuberculosis and neglected tropical diseases
36. Monoclonal antibody binding to the macrophage-specific receptor sialoadhesin alters the phagocytic properties of human and mouse macrophages
37. In vitro CYP1A activity in the zebrafish: temporal but low metabolite levels during organogenesis and lack of gender differences in the adult stage
38. Ontogeny of drug metabolism in the zebrafish: An in vitro study using human CYP-specific substrates
39. Characterizing the in vitro biofilm phenotype of Staphylococcus epidermidis isolates from central venous catheters
40. The role of the globin-coupled sensor YddV in a mature E. coli biofilm population
41. Optimization and validation of an existing, surgical and robust dry eye rat model for the evaluation of therapeutic compounds
42. In vitro screening of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives as antiprotozoal agents and docking studies on Trypanosoma cruzi CYP51
43. Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals
44. The malaria co-infection challenge: An investigation into the antimicrobial activity of selected Guinean medicinal plants
45. Repurposing of the Open Access Malaria Box for Kinetoplastid Diseases Identifies Novel Active Scaffolds against Trypanosomatids
46. Development of a novel in vitro onychomycosis model for the evaluation of topical antifungal activity
47. Fragment-Based Screening in Tandem with Phenotypic Screening Provides Novel Antiparasitic Hits
48. Flow Cytometric Enumeration of Bacteria Using TO-PRO®-3 Iodide as a Single-Stain Viability Dye
49. Hypoestenonols A and B, new fusicoccane diterpenes from Hypoestes forskalei
50. From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds
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