26 results on '"Manasyan A"'
Search Results
2. Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting
- Author
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Joy E Lawn, Eric O Ohuma, Ellen Bradley, Lorena Suárez Idueta, Elizabeth Hazel, Yemisrach B Okwaraji, Daniel J Erchick, Judith Yargawa, Joanne Katz, Anne C C Lee, Mike Diaz, Mihretab Salasibew, Jennifer Requejo, Chika Hayashi, Ann-Beth Moller, Elaine Borghi, Robert E Black, Hannah Blencowe, Per Ashorn, Ulla Ashorn, Nigel Klein, G Justus Hofmeyr, Marleen Temmerman, Sufia Askari, Samuel Chakwera, Laith Hussain-Alkhateeb, Alexandra Lewin, Wahyu Retno Mahanani, Emily White Johansson, Tina Lavin, Diana Estevez Fernandez, Giovanna Gatica Domínguez, Ayesha de Costa, Jenny A Cresswell, Julia Krasevec, Allisyn C Moran, Veronica Pingray, Gabriela Cormick, Luz Gibbons, José Belizan, Carlos Guevel, Kara Warrilow, Adrienne Gordon, Vicki Flenady, Jessica Sexton, Harriet Lawford, Enny S. Paixao, Ila Rocha Falcão, Mauricio Lima Barreto, Sarka Lisonkova, Qi Wen, Francisco Mardones, Raúl Caulier-Cisterna, José Acuña, Petr Velebil, Jitka Jirova, Erzsébet Horváth-Puhó, Henrik Toft Sørensen, Luule Sakkeus, Liili Abuladze, Mika Gissler, Maziar Moradi-Lakeh, Mohammad Heidarzadeh, Narjes Khalili, Khalid A. Yunis, Ayah Al Bizri, Pascale Nakad, Shamala Devi Karalasingam, J Ravichandran R Jeganathan, Nurakman binti Baharum, Lorena Suárez-Idueta, Arturo Barranco Flores, Jesus F Gonzalez Roldan, Sonia Lopez Alvarez, Aimée E. van Dijk, Lisa Broeders, Luis Huicho, Hugo G Quezada Pinedo, Kim N Cajachagua-Torres, Rodrigo M Carrillo-Larco, Carla Estefania Tarazona Meza, Wilmer Cristobal Guzman-Vilca, Tawa O. Olukade, Hamdy A. Ali, Fawziya Alyafei, Mai AlQubaisi, Mohamad R Alturk, Ho Yeon Kim, Geum Joon Cho, Neda Razaz, Jonas Söderling, Lucy K Smith, Jennifer J Kurinczuk, Ruth J Matthews, Bradley N Manktelow, Elizabeth S Draper, Alan C Fenton, Estelle Lowry, Neil Rowland, Rachael Wood, Kirsten Monteath, Isabel Pereyra, Gabriella Pravia, Celina Davis, Samantha Clarke, Lee S.F. Wu, Sachiyo Yoshida, Rajiv Bahl, Carlos Grandi, Alain B Labrique, Mabhubur Rashid, Salahuddin Ahmed, Arunangshu D. Roy, Rezwanul Haque, Saijuddin Shaikh, Abdullah H. Baqui, Samir K. Saha, Rasheda Khanam, Sayedur Rahman, Roger Shapiro, Rebecca Zash, Mariângela F. Silveira, Romina Buffarini, Patrick Kolsteren, Carl Lachat, Lieven Huybregts, Dominique Roberfroid, Lingxia Zeng, Zhonghai Zhu, Jianrong He, Xiu Qui, Seifu H. Gebreyesus, Kokeb Tesfamariam, Delayehu Bekele, Grace Chan, Estifanos Baye, Firehiwot Workneh, Kwaku P. Asante, Ellen Boanmah-Kaali, Seth Adu-Afarwuah, Kathryn G. Dewey, Stephaney Gyaase, Blair J. Wylie, Betty R. Kirkwood, Alexander Manu, Ravilla D Thulasiraj, James Tielsch, Ranadip Chowdhury, Sunita Taneja, Giridhara R Babu, Prafulla Shriyan, Kenneth Maleta, Charles Mangani, Sandra Acevedo-Gallegos, Maria J. Rodriguez-Sibaja, Subarna K. Khatry, Steven C. LeClerq, Luke C. Mullany, Fyezah Jehan, Muhammad Ilyas, Stephen J. Rogerson, Holger W. Unger, Rakesh Ghosh, Sabine Musange, Vundli Ramokolo, Wanga Zembe-Mkabile, Marzia Lazzerini, Rishard Mohamed, Dongqing Wang, Wafaie W. Fawzi, Daniel T.R. Minja, Christentze Schmiegelow, Honorati Masanja, Emily Smith, John P.A. Lusingu, Omari A. Msemo, Fathma M. Kabole, Salim N. Slim, Paniya Keentupthai, Aroonsri Mongkolchati, Richard Kajubi, Abel Kakuru, Peter Waiswa, Dilys Walker, Davidson H. Hamer, Katherine E.A. Semrau, Enesia B. Chaponda, R. Matthew Chico, Bowen Banda, Kebby Musokotwane, Albert Manasyan, Jake M. Pry, Bernard Chasekwa, Jean Humphrey, Abu Ahmed Shamim, Parul Christian, Hasmot Ali, Rolf D.W. Klemm, Alan B. Massie, Maithili Mitra, Sucheta Mehra, Kerry J. Schulze, Abu Amed Shamim, Alfred Sommer, Barkat Ullah, Keith P. West, Nazma Begum, Nabidul Haque Chowdhury, Shafiqul Islam, Dipak Kumar Mitra, Abdul Quaiyum, Modiegi Diseko, Joseph Makhema, Yue Cheng, Yixin Guo, Shanshan Yuan, Meselech Roro, Bilal Shikur, Frederick Goddard, Sebastien Haneuse, Bezawit Hunegnaw, Yemane Berhane, Alemayehu Worku, Seyram Kaali, Charles D. Arnold, Darby Jack, Seeba Amenga-Etego, Lisa Hurt, Caitlin Shannon, Seyi Soremekun, Nita Bhandari, Jose Martines, Sarmila Mazumder, Yamuna Ana, Deepa R, Lotta Hallamaa, Juha Pyykkö, Mario I. Lumbreras-Marquez, Claudia E. Mendoza-Carrera, Atiya Hussain, Muhammad Karim, Farzana Kausar, Usma Mehmood, Naila Nadeem, Muhammad Imran Nisar, Muhammad Sajid, Ivo Mueller, Maria Ome-Kaius, Elizabeth Butrick, Felix Sayinzoga, Ilaria Mariani, Willy Urassa, Thor Theander, Phillippe Deloron, Birgitte Bruun Nielsen, Alfa Muhihi, Ramadhani Abdallah Noor, Ib Bygbjerg, Sofie Lykke Moeller, Fahad Aftab, Said M. Ali, Pratibha Dhingra, Usha Dhingra, Arup Dutta, Sunil Sazawal, Atifa Suleiman, Mohammed Mohammed, Saikat Deb, Moses R. Kamya, Miriam Nakalembe, Jude Mulowooz, Nicole Santos, Godfrey Biemba, Julie M. Herlihy, Reuben K. Mbewe, Fern Mweena, Kojo Yeboah-Antwi, Jane Bruce, Daniel Chandramohan, and Andrew Prendergast
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General Medicine - Published
- 2023
3. Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting
- Author
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Lawn, Joy E, primary, Ohuma, Eric O, additional, Bradley, Ellen, additional, Idueta, Lorena Suárez, additional, Hazel, Elizabeth, additional, Okwaraji, Yemisrach B, additional, Erchick, Daniel J, additional, Yargawa, Judith, additional, Katz, Joanne, additional, Lee, Anne C C, additional, Diaz, Mike, additional, Salasibew, Mihretab, additional, Requejo, Jennifer, additional, Hayashi, Chika, additional, Moller, Ann-Beth, additional, Borghi, Elaine, additional, Black, Robert E, additional, Blencowe, Hannah, additional, Ashorn, Per, additional, Lawn, Joy E, additional, Ashorn, Ulla, additional, Klein, Nigel, additional, Hofmeyr, G Justus, additional, Temmerman, Marleen, additional, Askari, Sufia, additional, Chakwera, Samuel, additional, Hussain-Alkhateeb, Laith, additional, Lewin, Alexandra, additional, Retno Mahanani, Wahyu, additional, White Johansson, Emily, additional, Lavin, Tina, additional, Estevez Fernandez, Diana, additional, Gatica Domínguez, Giovanna, additional, de Costa, Ayesha, additional, Cresswell, Jenny A, additional, Krasevec, Julia, additional, Moran, Allisyn C, additional, Pingray, Veronica, additional, Cormick, Gabriela, additional, Gibbons, Luz, additional, Belizan, José, additional, Guevel, Carlos, additional, Warrilow, Kara, additional, Gordon, Adrienne, additional, Flenady, Vicki, additional, Sexton, Jessica, additional, Lawford, Harriet, additional, Paixao, Enny S., additional, Rocha Falcão, Ila, additional, Lima Barreto, Mauricio, additional, Lisonkova, Sarka, additional, Wen, Qi, additional, Mardones, Francisco, additional, Caulier-Cisterna, Raúl, additional, Acuña, José, additional, Velebil, Petr, additional, Jirova, Jitka, additional, Horváth-Puhó, Erzsébet, additional, Sørensen, Henrik Toft, additional, Sakkeus, Luule, additional, Abuladze, Liili, additional, Gissler, Mika, additional, Moradi-Lakeh, Maziar, additional, Heidarzadeh, Mohammad, additional, Khalili, Narjes, additional, A. Yunis, Khalid, additional, Al Bizri, Ayah, additional, Nakad, Pascale, additional, Devi Karalasingam, Shamala, additional, R Jeganathan, J Ravichandran, additional, binti Baharum, Nurakman, additional, Suárez-Idueta, Lorena, additional, Barranco Flores, Arturo, additional, Gonzalez Roldan, Jesus F, additional, Lopez Alvarez, Sonia, additional, van Dijk, Aimée E., additional, Broeders, Lisa, additional, Huicho, Luis, additional, Quezada Pinedo, Hugo G, additional, Cajachagua-Torres, Kim N, additional, Carrillo-Larco, Rodrigo M, additional, Tarazona Meza, Carla Estefania, additional, Guzman-Vilca, Wilmer Cristobal, additional, Olukade, Tawa O., additional, Ali, Hamdy A., additional, Alyafei, Fawziya, additional, AlQubaisi, Mai, additional, Alturk, Mohamad R, additional, Kim, Ho Yeon, additional, Cho, Geum Joon, additional, Razaz, Neda, additional, Söderling, Jonas, additional, Smith, Lucy K, additional, Kurinczuk, Jennifer J, additional, Matthews, Ruth J, additional, Manktelow, Bradley N, additional, Draper, Elizabeth S, additional, Fenton, Alan C, additional, Lowry, Estelle, additional, Rowland, Neil, additional, Wood, Rachael, additional, Monteath, Kirsten, additional, Pereyra, Isabel, additional, Pravia, Gabriella, additional, Davis, Celina, additional, Clarke, Samantha, additional, Wu, Lee S.F., additional, Yoshida, Sachiyo, additional, Bahl, Rajiv, additional, Grandi, Carlos, additional, Labrique, Alain B, additional, Rashid, Mabhubur, additional, Ahmed, Salahuddin, additional, Roy, Arunangshu D., additional, Haque, Rezwanul, additional, Shaikh, Saijuddin, additional, Baqui, Abdullah H., additional, Saha, Samir K., additional, Khanam, Rasheda, additional, Rahman, Sayedur, additional, Shapiro, Roger, additional, Zash, Rebecca, additional, Silveira, Mariângela F., additional, Buffarini, Romina, additional, Kolsteren, Patrick, additional, Lachat, Carl, additional, Huybregts, Lieven, additional, Roberfroid, Dominique, additional, Zeng, Lingxia, additional, Zhu, Zhonghai, additional, He, Jianrong, additional, Qui, Xiu, additional, Gebreyesus, Seifu H., additional, Tesfamariam, Kokeb, additional, Bekele, Delayehu, additional, Chan, Grace, additional, Baye, Estifanos, additional, Workneh, Firehiwot, additional, Asante, Kwaku P., additional, Boanmah-Kaali, Ellen, additional, Adu-Afarwuah, Seth, additional, Dewey, Kathryn G., additional, Gyaase, Stephaney, additional, Wylie, Blair J., additional, Kirkwood, Betty R., additional, Manu, Alexander, additional, Thulasiraj, Ravilla D, additional, Tielsch, James, additional, Chowdhury, Ranadip, additional, Taneja, Sunita, additional, Babu, Giridhara R, additional, Shriyan, Prafulla, additional, Maleta, Kenneth, additional, Mangani, Charles, additional, Acevedo-Gallegos, Sandra, additional, Rodriguez-Sibaja, Maria J., additional, Khatry, Subarna K., additional, LeClerq, Steven C., additional, Mullany, Luke C., additional, Jehan, Fyezah, additional, Ilyas, Muhammad, additional, Rogerson, Stephen J., additional, Unger, Holger W., additional, Ghosh, Rakesh, additional, Musange, Sabine, additional, Ramokolo, Vundli, additional, Zembe-Mkabile, Wanga, additional, Lazzerini, Marzia, additional, Mohamed, Rishard, additional, Wang, Dongqing, additional, Fawzi, Wafaie W., additional, Minja, Daniel T.R., additional, Schmiegelow, Christentze, additional, Masanja, Honorati, additional, Smith, Emily, additional, Lusingu, John P.A., additional, Msemo, Omari A., additional, Kabole, Fathma M., additional, Slim, Salim N., additional, Keentupthai, Paniya, additional, Mongkolchati, Aroonsri, additional, Kajubi, Richard, additional, Kakuru, Abel, additional, Waiswa, Peter, additional, Walker, Dilys, additional, Hamer, Davidson H., additional, Semrau, Katherine E.A., additional, Chaponda, Enesia B., additional, Chico, R. Matthew, additional, Banda, Bowen, additional, Musokotwane, Kebby, additional, Manasyan, Albert, additional, Pry, Jake M., additional, Chasekwa, Bernard, additional, Humphrey, Jean, additional, Shamim, Abu Ahmed, additional, Christian, Parul, additional, Ali, Hasmot, additional, Klemm, Rolf D.W., additional, Massie, Alan B., additional, Mitra, Maithili, additional, Mehra, Sucheta, additional, Schulze, Kerry J., additional, Shamim, Abu Amed, additional, Sommer, Alfred, additional, Ullah, Barkat, additional, West, Keith P., additional, Begum, Nazma, additional, Chowdhury, Nabidul Haque, additional, Islam, Shafiqul, additional, Mitra, Dipak Kumar, additional, Quaiyum, Abdul, additional, Diseko, Modiegi, additional, Makhema, Joseph, additional, Cheng, Yue, additional, Guo, Yixin, additional, Yuan, Shanshan, additional, Roro, Meselech, additional, Shikur, Bilal, additional, Goddard, Frederick, additional, Haneuse, Sebastien, additional, Hunegnaw, Bezawit, additional, Berhane, Yemane, additional, Worku, Alemayehu, additional, Kaali, Seyram, additional, Arnold, Charles D., additional, Jack, Darby, additional, Amenga-Etego, Seeba, additional, Hurt, Lisa, additional, Shannon, Caitlin, additional, Soremekun, Seyi, additional, Bhandari, Nita, additional, Martines, Jose, additional, Mazumder, Sarmila, additional, Ana, Yamuna, additional, R, Deepa, additional, Hallamaa, Lotta, additional, Pyykkö, Juha, additional, Lumbreras-Marquez, Mario I., additional, Mendoza-Carrera, Claudia E., additional, Hussain, Atiya, additional, Karim, Muhammad, additional, Kausar, Farzana, additional, Mehmood, Usma, additional, Nadeem, Naila, additional, Nisar, Muhammad Imran, additional, Sajid, Muhammad, additional, Mueller, Ivo, additional, Ome-Kaius, Maria, additional, Butrick, Elizabeth, additional, Sayinzoga, Felix, additional, Mariani, Ilaria, additional, Urassa, Willy, additional, Theander, Thor, additional, Deloron, Phillippe, additional, Nielsen, Birgitte Bruun, additional, Muhihi, Alfa, additional, Noor, Ramadhani Abdallah, additional, Bygbjerg, Ib, additional, Moeller, Sofie Lykke, additional, Aftab, Fahad, additional, Ali, Said M., additional, Dhingra, Pratibha, additional, Dhingra, Usha, additional, Dutta, Arup, additional, Sazawal, Sunil, additional, Suleiman, Atifa, additional, Mohammed, Mohammed, additional, Deb, Saikat, additional, Kamya, Moses R., additional, Nakalembe, Miriam, additional, Mulowooz, Jude, additional, Santos, Nicole, additional, Biemba, Godfrey, additional, Herlihy, Julie M., additional, Mbewe, Reuben K., additional, Mweena, Fern, additional, Yeboah-Antwi, Kojo, additional, Bruce, Jane, additional, Chandramohan, Daniel, additional, and Prendergast, Andrew, additional
- Published
- 2023
- Full Text
- View/download PDF
4. Cervical cancer screening outcomes in Zambia, 2010–19: a cohort study
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Pry, Jake M, primary, Manasyan, Albert, additional, Kapambwe, Sharon, additional, Taghavi, Katayoun, additional, Duran-Frigola, Miquel, additional, Mwanahamuntu, Mulindi, additional, Sikazwe, Izukanji, additional, Matambo, Jane, additional, Mubita, Jack, additional, Lishimpi, Kennedy, additional, Malama, Kennedy, additional, and Bolton Moore, Carolyn, additional
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- 2021
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- View/download PDF
5. Early Skin-to-Skin Care with a Polyethylene Bag for Neonatal Hypothermia: A Randomized Clinical Trial
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Travers, Colm P., primary, Ramani, Manimaran, additional, Gentle, Samuel J., additional, Schuyler, Amelia, additional, Brown, Catherine, additional, Dills, Madeline M., additional, Davis, Claire B., additional, Mwenechanya, Musaku, additional, Chomba, Elwyn, additional, Aban, Inmaculada, additional, Manasyan, Albert, additional, Ambalavanan, Namasivayam, additional, and Carlo, Waldemar A., additional
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- 2021
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6. Early Skin-to-Skin Care with a Polyethylene Bag for Neonatal Hypothermia: A Randomized Clinical Trial
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Catherine Brown, Manimaran Ramani, Amelia Schuyler, Musaku Mwenechanya, Namasivayam Ambalavanan, Waldemar A. Carlo, Claire B. Davis, Elwyn Chomba, Madeline Dills, Albert Manasyan, Colm P. Travers, Inmaculada Aban, and Samuel J. Gentle
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Male ,Pediatrics ,medicine.medical_specialty ,Skin to skin ,Hypothermia ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Neonatal hypothermia ,Protective Clothing ,Randomized controlled trial ,law ,030225 pediatrics ,medicine ,Humans ,030212 general & internal medicine ,Trial registration ,Skin care ,integumentary system ,business.industry ,Infant, Newborn ,Combined Modality Therapy ,Kangaroo-Mother Care ,Kangaroo-Mother Care Method ,Treatment Outcome ,Polyethylene ,Pediatrics, Perinatology and Child Health ,Referral center ,Female ,medicine.symptom ,business - Abstract
To determine whether early polyethylene bag use with skin-to-skin care compared with skin-to skin care alone reduce hypothermia among infants born at term in resource-limited settings.Infants born at term in the tertiary referral center in Lusaka, Zambia, were randomized using sequentially numbered sealed opaque envelopes in 2 phases: after birth (phase 1) and at 1 hour after birth (phase 2) to either skin-to-skin care with polyethylene bags or skin-to-skin care alone. Infant and maternal temperatures were recorded at birth, 1 hour, and every 4 hours until discharge or 24 hours.We enrolled 423 infants from May 2017 to August 2017. The rate of moderate-severe hypothermia (temperature36.0°C) at 1 hour was 72 of 208 (34.6%) in the skin-to-skin care with a polyethylene bag group compared with 101 of 213 (47.4%) in the skin-to-skin care alone group (relative risk, 0.71; 95% CI 0.56-0.90; P .01; number needed to treat = 8). phase 1 treatment assignment significantly modified the effect of phase 2 treatment (P = .02 for interaction effect). Among infants randomized to skin-to-skin care with a polyethylene bag in phase 1, the risk of moderate-severe hypothermia was decreased in infants randomized to continue this intervention until discharge compared with infants randomized to skin-to-skin care alone. The rates of severe hypothermia, hyperthermia, and other adverse events did not differ significantly between groups.Low-cost polyethylene bags started after birth in combination with skin-to-skin care reduced moderate or severe hypothermia at 1 hour and at discharge among infants born at term in a resource-limited setting compared with skin-to-skin care alone.ClinicalTrials.gov: NCT03141723.
- Published
- 2021
7. A population-based, multifaceted strategy to implement antenatal corticosteroid treatment versus standard care for the reduction of neonatal mortality due to preterm birth in low-income and middle-income countries: the ACT cluster-randomised trial
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Lester Figueroa, Sumera Aziz Ali, Geetanjali Katageri, Patricia L. Hibberd, Fabian Esamai, K M Hambidge, Manjushri Waikar, Omrana Pasha, Elizabeth M. McClure, M. B. Bellad, Albert Manasyan, Richard J. Derman, Fernando Althabe, Paul Nyongesa, Kristen Stolka, Niranjana S. Mahantshetti, Bhalchandra S. Kodkany, Robert L. Goldenberg, Narayan V Honnungar, Sarah Saleem, A. Garces, Agustina Mazzoni, Ashlesha Patel, E. A. Liechty, Mrityunjay C Metgud, Waldemar A. Carlo, Dennis Wallace, S. Ayunga, José M. Belizán, Mabel Berrueta, Melody Chiwila, Alan H. Jobe, Sayury Pineda, Elwyn Chomba, Sreelatha Meleth, Anjali M Joshi, Pierre Buekens, Alvaro Ciganda, A. Mwiche, A. Bhandarkar, M. Koso-Thomas, Jennifer Hemingway-Foday, Farid Hasnain, Nancy F. Krebs, Shivaprasad S. Goudar, Vanessa Thorsten, and Sangappa M. Dhaded
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Rural Population ,Pediatrics ,neonatal mortality ,Urban Population ,Psychological intervention ,Ciencias de la Salud ,law.invention ,0302 clinical medicine ,Randomized controlled trial ,Adrenal Cortex Hormones ,Pregnancy ,law ,Infant Mortality ,Pakistan ,030212 general & internal medicine ,Cluster randomised controlled trial ,education.field_of_study ,030219 obstetrics & reproductive medicine ,Neonatal mortality ,Obstetrics ,Low income and middle income countries ,Prenatal Care ,General Medicine ,Antenatal corticosteroid ,Guatemala ,Premature birth ,Premature Birth ,Female ,medicine.symptom ,Infant, Premature ,Adult ,medicine.medical_specialty ,CIENCIAS MÉDICAS Y DE LA SALUD ,Birth weight ,Population ,Argentina ,India ,Zambia ,Population based ,Prenatal care ,Risk Assessment ,03 medical and health sciences ,Young Adult ,Standard care ,medicine ,Humans ,education ,Developing Countries ,Salud Ocupacional ,business.industry ,Infant, Newborn ,Infant ,Infant, Low Birth Weight ,medicine.disease ,Kenya ,Infant mortality ,Low birth weight ,Feasibility Studies ,Puerperal Infection ,business - Abstract
Background Antenatal corticosteroids for pregnant women at risk of preterm birth are among the most effective hospital-based interventions to reduce neonatal mortality. We aimed to assess the feasibility, effectiveness, and safety of a multifaceted intervention designed to increase the use of antenatal corticosteroids at all levels of health care in low-income and middle-income countries. Methods In this 18-month, cluster-randomised trial, we randomly assigned (1:1) rural and semi-urban clusters within six countries (Argentina, Guatemala, India, Kenya, Pakistan, and Zambia) to standard care or a multifaceted intervention including components to improve identification of women at risk of preterm birth and to facilitate appropriate use of antenatal corticosteroids. The primary outcome was 28-day neonatal mortality among infants less than the 5th percentile for birthweight (a proxy for preterm birth) across the clusters. Use of antenatal corticosteroids and suspected maternal infection were additional main outcomes. This trial is registered with ClinicalTrials.gov, number NCT01084096. Findings The ACT trial took place between October, 2011, and March, 2014 (start dates varied by site). 51 intervention clusters with 47 394 livebirths (2520 [5%] less than 5th percentile for birthweight) and 50 control clusters with 50 743 livebirths (2258 [4%] less than 5th percentile) completed follow-up. 1052 (45%) of 2327 women in intervention clusters who delivered less-than-5th-percentile infants received antenatal corticosteroids, compared with 215 (10%) of 2062 in control clusters (p
- Published
- 2015
8. Asymmetric synthesis of new β-heterocyclic (S)-α-aminopropionic acids
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Ashot S. Saghyan, L. L. Manasyan, Peter Langer, Hayarpi M. Simonyan, Nelli Hovhannisyan, Lala A. Stepanyan, Tariel V. Ghochikyan, Viktor O. Iaroshenko, Samvel G. Ghazaryan, Arpine V. Geolchanyan, Ashot Gevorgyan, and Vahe T. Ghochikyan
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Chiral auxiliary ,Schiff base ,Stereochemistry ,Organic Chemistry ,Enantioselective synthesis ,Decomposition ,Catalysis ,Inorganic Chemistry ,chemistry.chemical_compound ,chemistry ,Nucleophile ,Dehydroalanine ,Moiety ,Physical and Theoretical Chemistry ,Conjugate - Abstract
The asymmetric synthesis of novel non-proteinogenic β-heterocyclic α-amino acids via the diastereoselective conjugate addition of heterocyclic nucleophiles to the dehydroalanine moiety of chiral Ni(II) complexes has been studied. The complexes were formed from the Schiff base of dehydroalanine using (S)-2-N-(N-benzylprolyl)aminobenzophenone as a chiral auxiliary. After decomposition of the complexes, the α-amino acids were isolated with 30–99% ee.
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- 2012
9. Rapid asymmetric synthesis of amino acids via NiII complexes based on new fluorine containing chiral auxiliaries
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Slavik Arshak Dadayan, Victor I. Maleev, Hrant R. Ajvazyan, Ani Slavik Dadayan, Anna F. Mkrtchyan, Ashot S. Saghyan, Hasmik H. Hambardzumyan, Arpine V. Geolchanyan, Victor N. Khrustalev, and Luiza L. Manasyan
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Inorganic Chemistry ,Alanine ,chemistry.chemical_classification ,Reaction rate ,Stereochemistry ,Chemistry ,Organic Chemistry ,Glycine ,Enantioselective synthesis ,Fluorine containing ,Physical and Theoretical Chemistry ,Catalysis ,Amino acid - Abstract
New fluorine-containing chiral auxiliaries ( S )- N -(2-benzoylphenyl)-1-(2-fluorobenzyl)-, ( S )- N -(2-benzoylphenyl)-1-(3-fluorobenzyl)-, and ( S )- N -(2-benzoylphenyl)-1-(4-fluorobenzyl)-pyrrolidine-2-carboxamide and their Ni II complexes of Schiff bases with glycine and alanine have been synthesized. The greater efficiency of the complexes in terms of faster reaction rates and stereoselectivities in the asymmetric synthesis of ( S )-α-amino acids has also been demonstrated.
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- 2010
10. Synthesis of novel chiral NiII complexes of dehydroalanine Schiff bases and their reactivity in asymmetric nucleophilic addition reactions. Novel synthesis of (S)-2-carboxypiperazine
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Luiza L. Manasyan, V. I. Maleev, Arpine V. Geolchanyan, Henry A. Panosyan, Tatiana F. Savel'eva, Lala A. Stepanyan, Hrant R. Ajvazyan, Ashot S. Saghiyan, and Silva M. Djamgaryan
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Chiral auxiliary ,Primary (chemistry) ,Nucleophilic addition ,Chemistry ,Stereochemistry ,Organic Chemistry ,Catalysis ,Inorganic Chemistry ,chemistry.chemical_compound ,Dehydroalanine ,Michael reaction ,Reactivity (chemistry) ,Physical and Theoretical Chemistry ,Selectivity - Abstract
New chiral NiII complexes of Schiff bases of dehydroalanine with modified chiral auxiliaries (S)-2-N-[N′-(3,4-dichlorobenzyl)prolyl]aminobenzophenone (3,4-DCBPB), (S)-2-N-[N′-(3,4-dimethylbenzyl)prolyl]aminobenzophenone (3,4-DMBPB), (S)-2-N-[N′-(2-chlorobenzyl)prolyl]aminobenzophenone (2-CBPB), and (S)-2-N-[N′-(2-fluorobenzyl)prolyl]-aminobenzophenone (2-FBPB) have been synthesized. Asymmetric Michael addition reactions of primary and secondary amines and thiols to the dehydroalanine moieties of the complexes were studied. (S)-2-FBPB was found to be the best chiral auxiliary in terms of both selectivity of the reactions (de ∼92–96%) and reactivity of the complexes. A novel synthetic route toward (S)-2-carboxypiperazine was developed based on the auxiliary.
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- 2010
11. New chiral NiII complexes of Schiff’s bases of glycine and alanine for efficient asymmetric synthesis of α-amino acids
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A. S. Saghiyan, Victor N. Khrustalev, Arpine V. Geolchanyan, Satenik G. Petrosyan, Luisa L. Manasyan, Silva M. Djamgaryan, Victor I. Maleev, Sargis A. Andreasyan, and Slavik A. Dadayan
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Inorganic Chemistry ,Alanine ,chemistry.chemical_classification ,Base (chemistry) ,chemistry ,Stereochemistry ,Organic Chemistry ,Glycine ,Enantioselective synthesis ,Aldol condensation ,Physical and Theoretical Chemistry ,Catalysis ,Amino acid - Abstract
New modified chiral auxiliaries (S)-N-(2-benzoylphenyl)-1-(2-chlorobenzyl)pyrrolidine-2-carboxamide (2-CBPB) and (S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide (3,4-DMBPB) and their NiII complexes of Schiff’s base with glycine and alanine have been synthesized and tested in asymmetric C-alkylation and aldol condensation reactions of amino acid moieties. The tests proved that both new auxiliaries were efficient with the ee’s of the final amino acids as high as 98% even in case of α-methyl-α-amino acid synthesis.
- Published
- 2006
12. A population-based, multifaceted strategy to implement antenatal corticosteroid treatment versus standard care for the reduction of neonatal mortality due to preterm birth in low-income and middle-income countries: the ACT cluster-randomised trial
- Author
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Althabe, Fernando, primary, Belizán, José M, additional, McClure, Elizabeth M, additional, Hemingway-Foday, Jennifer, additional, Berrueta, Mabel, additional, Mazzoni, Agustina, additional, Ciganda, Alvaro, additional, Goudar, Shivaprasad S, additional, Kodkany, Bhalachandra S, additional, Mahantshetti, Niranjana S, additional, Dhaded, Sangappa M, additional, Katageri, Geetanjali M, additional, Metgud, Mrityunjay C, additional, Joshi, Anjali M, additional, Bellad, Mrutyunjaya B, additional, Honnungar, Narayan V, additional, Derman, Richard J, additional, Saleem, Sarah, additional, Pasha, Omrana, additional, Ali, Sumera, additional, Hasnain, Farid, additional, Goldenberg, Robert L, additional, Esamai, Fabian, additional, Nyongesa, Paul, additional, Ayunga, Silas, additional, Liechty, Edward A, additional, Garces, Ana L, additional, Figueroa, Lester, additional, Hambidge, K Michael, additional, Krebs, Nancy F, additional, Patel, Archana, additional, Bhandarkar, Anjali, additional, Waikar, Manjushri, additional, Hibberd, Patricia L, additional, Chomba, Elwyn, additional, Carlo, Waldemar A, additional, Mwiche, Angel, additional, Chiwila, Melody, additional, Manasyan, Albert, additional, Pineda, Sayury, additional, Meleth, Sreelatha, additional, Thorsten, Vanessa, additional, Stolka, Kristen, additional, Wallace, Dennis D, additional, Koso-Thomas, Marion, additional, Jobe, Alan H, additional, and Buekens, Pierre M, additional
- Published
- 2015
- Full Text
- View/download PDF
13. P.2.a.009 Efficacy of tianeptine in the treatment of depressive disorders according to Hamilton depression rating scale
- Author
-
S.H. Sukiasyan, N.G. Manasyan, A.A. Babakhanyan, S.P. Margaryan, and A.L. Kirakosyan
- Subjects
Pharmacology ,medicine.medical_specialty ,business.industry ,Psychiatry and Mental health ,Neurology ,Rating scale ,medicine ,Pharmacology (medical) ,Tianeptine ,Neurology (clinical) ,Psychiatry ,business ,Biological Psychiatry ,Depression (differential diagnoses) ,medicine.drug - Published
- 2007
14. 0236 THE DETECTION OF FIRST EPISODE PSYCHOSIS AND SOCIAL-PSYCHOLOGICAL FACTORS: A MAJOR PUBLIC HEALTH ISSUE IN ARMENIA
- Author
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N.G. Manasyan, S.H. Sukiasyan, S.P. Margaryan, A.L. Kirakosyan, A.A. Babakhanyan, and A.N. Poghosyan
- Subjects
Psychiatry and Mental health ,medicine.medical_specialty ,Public health ,First episode psychosis ,medicine ,Psychology ,Psychiatry ,Biological Psychiatry ,Clinical psychology - Published
- 2006
15. Randomized controlled trial of meat compared with multimicronutrient-fortified cereal in infants and toddlers with high stunting rates in diverse settings
- Author
-
Krebs, Nancy F, primary, Mazariegos, Manolo, additional, Chomba, Elwyn, additional, Sami, Neelofar, additional, Pasha, Omrana, additional, Tshefu, Antoinette, additional, Carlo, Waldemar A, additional, Goldenberg, Robert L, additional, Bose, Carl L, additional, Wright, Linda L, additional, Koso-Thomas, Marion, additional, Goco, Norman, additional, Kindem, Mark, additional, McClure, Elizabeth M, additional, Westcott, Jamie, additional, Garces, Ana, additional, Lokangaka, Adrien, additional, Manasyan, Albert, additional, Imenda, Edna, additional, Hartwell, Tyler D, additional, and Hambidge, K Michael, additional
- Published
- 2012
- Full Text
- View/download PDF
16. Asymmetric synthesis of new β-heterocyclic (S)-α-aminopropionic acids
- Author
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Saghyan, Ashot S., primary, Simonyan, Hayarpi M., additional, Stepanyan, Lala A., additional, Ghazaryan, Samvel G., additional, Geolchanyan, Arpine V., additional, Manasyan, Luiza L., additional, Ghochikyan, Vahe T., additional, Ghochikyan, Tariel V., additional, Hovhannisyan, Nelli A., additional, Gevorgyan, Ashot, additional, Iaroshenko, Viktor O., additional, and Langer, Peter, additional
- Published
- 2012
- Full Text
- View/download PDF
17. Rapid asymmetric synthesis of amino acids via NiII complexes based on new fluorine containing chiral auxiliaries
- Author
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Saghyan, Ashot S., primary, Dadayan, Ani S., additional, Dadayan, Slavik A., additional, Mkrtchyan, Anna F., additional, Geolchanyan, Arpine V., additional, Manasyan, Luiza L., additional, Ajvazyan, Hrant R., additional, Khrustalev, Victor N., additional, Hambardzumyan, Hasmik H., additional, and Maleev, Victor I., additional
- Published
- 2010
- Full Text
- View/download PDF
18. Synthesis of novel chiral NiII complexes of dehydroalanine Schiff bases and their reactivity in asymmetric nucleophilic addition reactions. Novel synthesis of (S)-2-carboxypiperazine
- Author
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Saghiyan, Ashot S., primary, Stepanyan, Lala A., additional, Manasyan, Luiza L., additional, Geolchanyan, Arpine V., additional, Djamgaryan, Silva M., additional, Ajvazyan, Hrant R., additional, Panosyan, Henry A., additional, Maleev, Viktor I., additional, and Saveleva, Tatiana F., additional
- Published
- 2010
- Full Text
- View/download PDF
19. O.519 The efflcacy of postoperative immunomodulating therapy in odontogenic pyogenic infections
- Author
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Osipyan, E., primary, Malichenko, N., additional, Vasilenko, I., additional, and Manasyan, G., additional
- Published
- 2008
- Full Text
- View/download PDF
20. P.2.a.009 Efficacy of tianeptine in the treatment of depressive disorders according to Hamilton depression rating scale
- Author
-
Margaryan, S.P., primary, Sukiasyan, S.H., additional, Manasyan, N.G., additional, Babakhanyan, A.A., additional, and Kirakosyan, A.L., additional
- Published
- 2007
- Full Text
- View/download PDF
21. O.519 The efflcacy of postoperative immunomodulating therapy in odontogenic pyogenic infections
- Author
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I. Vasilenko, N. Malichenko, G. Manasyan, and E. Osipyan
- Subjects
medicine.medical_specialty ,Otorhinolaryngology ,business.industry ,Medicine ,Surgery ,Oral Surgery ,business ,Dermatology ,Odontogenic - Published
- 2008
22. Asymmetric synthesis of anti-diastereoisomers of β-heterocycle substituted (S)-α-aminobutyric acids
- Author
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Saghiyan, Ashot S., primary, Manasyan, Luisa L., additional, Geolchanyan, Arpine V., additional, Hovhannisyan, Anahit M., additional, Ghochikyan, Tariel V., additional, Haroutunyan, Vilik S., additional, Avetisyan, Aida A., additional, Mirzoyan, Koryun S., additional, Maleev, Victor I., additional, and Khrustalev, Victor N., additional
- Published
- 2006
- Full Text
- View/download PDF
23. 0236 THE DETECTION OF FIRST EPISODE PSYCHOSIS AND SOCIAL-PSYCHOLOGICAL FACTORS: A MAJOR PUBLIC HEALTH ISSUE IN ARMENIA
- Author
-
Margaryan, S.P., primary, Sukiasyan, S.H., additional, Manasyan, N.G., additional, Babakhanyan, A.A., additional, Kirakosyan, A.L., additional, and Poghosyan, A.N., additional
- Published
- 2006
- Full Text
- View/download PDF
24. New chiral NiII complexes of Schiff’s bases of glycine and alanine for efficient asymmetric synthesis of α-amino acids
- Author
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Saghiyan, Ashot S., primary, Dadayan, Slavik A., additional, Petrosyan, Satenik G., additional, Manasyan, Luisa L., additional, Geolchanyan, Arpine V., additional, Djamgaryan, Silva M., additional, Andreasyan, Sargis A., additional, Maleev, Victor I., additional, and Khrustalev, Victor N., additional
- Published
- 2006
- Full Text
- View/download PDF
25. Some unusual properties of neurones in the cat posterotemporal cortex
- Author
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K.A. Manasyan and I.A. Shevelev
- Subjects
Time Factors ,Eye Movements ,Adaptation level ,Photometry ,Optics ,medicine ,Animals ,Invariant (mathematics) ,Neurons ,Physics ,Brain Mapping ,business.industry ,Eye movement ,Temporal Lobe ,Sensory Systems ,Visual field ,Ophthalmology ,Visual cortex ,medicine.anatomical_structure ,Receptive field ,Cerebral cortex ,Cats ,Evoked Potentials, Visual ,Visual Fields ,business ,Neuroscience - Abstract
Visual receptive fields (RF) of 103 single units in posterotemporal cortex (area 21) were investigated in cats immobilized by d-tubocurarine. The method of express-mapping of the RF allows to estimate every 3.3 min its localization, size and configuration. A considerable variability of RF size and form was revealed in 35% of units. In 88% of the unit studied the RFs were invariant with adaptation level. Little dependence of the response on the length of the light bar, but a definite orientational sensitivity was found. Spontaneous displacements of the RF in the visual field are found in 14% of the visually activated cells. Such RF dislocations varied in magnitude from 3.5 upto 25 degrees and were mainly horizontal. The mechanisms of RF variability and displacement in the visual field are discussed in connection with possible influence of the copy of the motor command that introduces corrections in the visual coordinates in area 21 to provide for the constancy of vision.
- Published
- 1984
26. Some unusual properties of neurones in the cat posterotemporal cortex
- Author
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Shevelev, I.A., primary and Manasyan, K.A., additional
- Published
- 1984
- Full Text
- View/download PDF
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