1. Saponins from the roots of Panax notoginseng
- Author
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Masanori Mizutani, Wei Guang Ma, Bertrand Ducrey, Satoshi Tahara, Shao Long Lu, and Karl Egil Malterud
- Subjects
chemistry.chemical_classification ,biology ,Stereochemistry ,Saponin ,Glycoside ,Glycosidic bond ,Biological activity ,Plant Science ,General Medicine ,Horticulture ,biology.organism_classification ,Biochemistry ,Aphanomyces cochlioides ,chemistry.chemical_compound ,chemistry ,Ginsenoside ,Araliaceae ,Panax notoginseng ,Molecular Biology - Abstract
The glycosidic fraction from the dried roots of Panax notoginseng (Burk.) F.H.Chen exhibited an inhibitory effect on zoospore motility of Aphanomyces cochlioides . Further study on this fraction afforded fourteen dammarane-type saponins. Their structures were determined on the basis of spectroscopic and chemical methods. Eleven were known compounds, and the three new ones were 3- O -[β- d -glucopyranosyl (1→6)-β- d -glucopyranosyl]-20- O -β- d -glucopyranosyl 3β, 12β, 20 ( S )-trihydroxydammar-24-ene, 3- O -β- d -glucopyranosyl 20- O -[α- l -arabinopyranosyl (1→2)-β- d -glucopyranosyl] 3β, 12β, 20 ( S )-trihydroxydammar-24-ene and 6- O -β- d -glucopyranosyl 20- O -β- d -glucopyranosyl 3β, 6α, 12β, 20 ( S ), 25-pentahydroxydammar-23-ene, respectively. Each saponin displayed good inhibitory effects on zoospore motility.
- Published
- 1999
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