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Your search keyword '"McKerlie, Colin"' showing total 13 results
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13 results on '"McKerlie, Colin"'

1. Co-expression of prepulse inhibition and schizophrenia genes in the mouse and human brain

Author

Garrett, Lillian, primary, Trümbach, Dietrich, additional, Lee, Dongyhung, additional, Mandillo, Silvia, additional, Samaco, Rodney, additional, Flenniken, Ann M., additional, Stewart, Michelle, additional, Aguilar-Pimental, Juan A., additional, Amarie, Oana V., additional, Becker, Lore, additional, Calzada-Wack, Julia, additional, Da Silva-Buttkus, Patricia, additional, Dragano, Nathalia, additional, Kraiger, Markus, additional, Lengger, Christoph, additional, Leuchtenberger, Stefanie, additional, Marschall, Susan, additional, Oestereicher, Manuela A., additional, Rathkolb, Birgit, additional, Sanz-Moreno, Adrián, additional, Seisenberger, Claudia, additional, Spielmann, Nadine, additional, Stoeger, Claudia, additional, Kumar, Vivek, additional, Keskivali, Piia, additional, King, Ruairidh, additional, Haselimashhadi, Hamed, additional, Bezginov, Alexandr, additional, Norris, Clare, additional, Taylor, Sarah, additional, Pimm, Dale, additional, Kelsey, Lois, additional, Berberovic, Zorana, additional, Qu, Dawei, additional, D'Souza, Abigail, additional, Bradaschia, Vivian, additional, Eskandarian, Mohammed, additional, Shang, Xueyuan, additional, Duffin, Kyle, additional, Roberton, Kyle, additional, Xu, Catherine, additional, Baguinat, Gloria, additional, Laurin, Valerie, additional, Lan, Qing, additional, Sleep, Gillian, additional, Lintott, Lauri, additional, Gertsenstein, Marina, additional, Tondat, Sandra, additional, Cruz, Maribelle, additional, Miller, David, additional, Sorg, Tania, additional, Riet, Fabrice, additional, Tolentino, Heather, additional, Tolentino, Todd, additional, Schuchbauer, Mike, additional, Hockenbury, Nichole, additional, Beeman, Karrie, additional, Pedroia, Sheryl, additional, Salazar, Jason, additional, Heffner, Mollie, additional, Hsu, Joanne, additional, Fletcher, Colin, additional, Vanzanten, Maya, additional, Golini, Elisabetta, additional, Seavitt, John R., additional, Lanza, Denise G., additional, Lorenzo, Isabel, additional, Gaspero, Angelina, additional, Rios, Amanda, additional, White, Jacqueline K., additional, McKerlie, Colin, additional, Nutter, Lauryl M.J., additional, Vukobradovic, Igor, additional, Veeraragavan, Surabi, additional, Yuva, Lisa, additional, Heaney, Jason D., additional, Dickinson, Mary E., additional, Meziane, Hamid, additional, Hérault, Yann, additional, Wells, Sara, additional, Lloyd, K.C.Kent, additional, Bower, Lynette, additional, Lanoue, Louise, additional, Clary, Dave, additional, Zimprich, Annemarie, additional, Gailus-Durner, Valerie, additional, Fuchs, Helmut, additional, Brown, Steve D.M., additional, Chesler, Elissa J., additional, Wurst, Wolfgang, additional, Hrabě de Angelis, Martin, additional, and Hölter, Sabine M., additional

Published
2024
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7. Respiratory Distress and Neonatal Lethality in Mice Lacking Golgi α1,2-Mannosidase IB Involved in N-Glycan Maturation

Author

Tremblay, Linda O., primary, Kovács, Erzsebet Nagy, additional, Daniels, Eugene, additional, Wong, Nyet Kui, additional, Sutton-Smith, Mark, additional, Morris, Howard R., additional, Dell, Anne, additional, Marcinkiewicz, Edwige, additional, Seidah, Nabil G., additional, McKerlie, Colin, additional, and Herscovics, Annette, additional

Published
2007
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11. Primary Sjögren's syndrome and deficiency of ICA69

Author

Winer, Shawn, primary, Astsaturov, Igor, additional, Cheung, Roy, additional, Tsui, Hubert, additional, Song, Aihua, additional, Gaedigk, Roger, additional, Winer, Daniel, additional, Sampson, Anastasia, additional, McKerlie, Colin, additional, Bookman, Arthur, additional, and Dosch, H-Michael, additional

Published
2002
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12. 685. Epithelium-Specific Gene Therapy Vector Protects Cftr Knockout Mice from Acute Lung Infection

Author

Keith Tanswell, Allan L. Coates, Forstner F. Janet, Jim Hu, Umadevi S. Sajjan, McKerlie Colin, and David R. Koehler

Subjects
Pharmacology, Lung, Genetic enhancement, respiratory system, Biology, medicine.disease, Cystic fibrosis, Molecular biology, Epithelium, respiratory tract diseases, Viral vector, medicine.anatomical_structure, Drug Discovery, Knockout mouse, Gene expression, Immunology, Genetics, medicine, Molecular Medicine, Respiratory epithelium, Molecular Biology
Abstract

Development of safe and effective vectors remains a major challenge for lung gene therapy. We developed a helper-dependent adenoviral vector for cystic fibrosis (CF) lung gene therapy, using epithelium-specific control elements to drive expression of the CF transmembrane conductance regulator (Cftr) gene. The vector expressed properly localized CFTR in human CF bronchial epithelial cells cultured at an air-liquid interface. Following a single intranasal dose, the vector expressed human CFTR specifically in the airway epithelium of mice, for up to 3 months. Acute inflammation was minimal to moderate. CFTR protein was also detected in the airway epithelium of 2 month-old mice that received one vector dose postnatally. Delivery of the vector to rabbit lung, in an aerosol containing surfactant, yielded strong gene expression (lacZ reporter) specifically in the airway epithelium, including trachea, bronchi, and bronchioles.

Published
2004

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