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33 results on '"Morales-Suárez-Varela M"'

7. Wireless phone use in childhood and adolescence and neuroepithelial brain tumours: Results from the international MOBI-Kids study

Author

Castaño-Vinyals, G, Sadetzki, S, Vermeulen, R, Momoli, F, Kundi, M, Merletti, F, Maslanyj, M, Calderon, C, Wiart, J, Lee, A-K, Taki, M, Sim, M, Armstrong, B, Benke, G, Schattner, R, Hutter, H-P, Krewski, D, Mohipp, C, Ritvo, P, Spinelli, J, Lacour, B, Remen, T, Radon, K, Weinmann, T, Petridou, E Th, Moschovi, M, Pourtsidis, A, Oikonomou, K, Kanavidis, P, Bouka, E, Dikshit, R, Nagrani, R, Chetrit, A, Bruchim, R, Maule, M, Migliore, E, Filippini, G, Miligi, L, Mattioli, S, Kojimahara, N, Yamaguchi, N, Ha, M, Choi, K, Kromhout, H, Goedhart, G, 't Mannetje, A, Eng, A, Langer, C E, Alguacil, J, Aragonés, N, Morales-Suárez-Varela, M, Badia, F, Albert, A, Carretero, G, Cardis, E, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, IRAS OH Epidemiology Chemical Agents, and dIRAS RA-2

Subjects
Adult, Male, Adolescent, Radio Waves, Cell phones, Socio-culturale, Brain tumors, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Electromagnetic Fields, Economica, Environmental Science(all), Tumors cerebrals, Humans, GE1-350, Mobile phones, 030212 general & internal medicine, Child, Wireless phones, Brain tumours, Young people, Extremely low frequency electromagnetic fields, Radiofrequency radiation, General Environmental Science, Brain Neoplasms, Ambientale, Glioma, 3. Good health, Environmental sciences, Telèfon mòbil, 030220 oncology & carcinogenesis, Case-Control Studies, Cell Phone
Abstract

In recent decades, the possibility that use of mobile communicating devices, particularly wireless (mobile and cordless) phones, may increase brain tumour risk, has been a concern, particularly given the considerable increase in their use by young people. MOBI-Kids, a 14-country (Australia, Austria, Canada, France, Germany, Greece, India, Israel, Italy, Japan, Korea, the Netherlands, New Zealand, Spain) case-control study, was conducted to evaluate whether wireless phone use (and particularly resulting exposure to radiofrequency (RF) and extremely low frequency (ELF) electromagnetic fields (EMF)) increases risk of brain tumours in young people. Between 2010 and 2015, the study recruited 899 people with brain tumours aged 10 to 24 years old and 1,910 controls (operated for appendicitis) matched to the cases on date of diagnosis, study region and age. Participation rates were 72% for cases and 54% for controls. The mean ages of cases and controls were 16.5 and 16.6 years, respectively; 57% were males. The vast majority of study participants were wireless phones users, even in the youngest age group, and the study included substantial numbers of long-term (over 10 years) users: 22% overall, 51% in the 20-24-year-olds. Most tumours were of the neuroepithelial type (NBT; n = 671), mainly glioma. The odds ratios (OR) of NBT appeared to decrease with increasing time since start of use of wireless phones, cumulative number of calls and cumulative call time, particularly in the 15-19 years old age group. A decreasing trend in ORs was also observed with increasing estimated cumulative RF specific energy and ELF induced current density at the location of the tumour. Further analyses suggest that the large number of ORs below 1 in this study is unlikely to represent an unknown causal preventive effect of mobile phone exposure: they can be at least partially explained by differential recall by proxies and prodromal symptoms affecting phone use before diagnosis of the cases. We cannot rule out, however, residual confounding from sources we did not measure. Overall, our study provides no evidence of a causal association between wireless phone use and brain tumours in young people. However, the sources of bias summarised above prevent us from ruling out a small increased risk. Funding for the coordination of the MOBI-Kids study was obtained from the European Community's Seventh Framework Programme under grant agreements number 226873 and 603794, and from the Spanish Ministry of Science and Innovation (MINECO). In Spain, additional funding was obtained from the Spanish Health Research Fund (FIS) of the National Institute for Health Carlos III, and from the Junta de Andalucía, Consejería de Salud. Proyecto PI-0317-2010. ISGlobal also acknowledges support from the Spanish Ministry of Science, Innovation and Universities through the “Centro de Excelencia Severo Ochoa 2019-2023” Program (CEX2018-000806-S), support from the Generalitat de Catalunya through the CERCA Program and support from the Secretariat of Universities and Research of the Department of Business and Knowledge of the Generalitat of Catalonia through AGAUR (the Catalan Agency for Management of University and Research Grants) (Project 2017 SGR 1487). Australian participation in MOBI-Kids was supported by the Australian National Health and Medical Research Council with a five-year research grant (grant number: 546130). Austrian participation in MOBI-Kids was partly supported by a grant from the Ministry of Science. In Canada, participation in MOBI-Kids was supported by a university-industry partnership grant from the Canadian Institutes of Health Research (CIHR), reference number 110835, with the Canadian Wireless Telecommunications Association (CWTA) serving as the industrial partner. CWTA provides technical information on wireless telecommunications in Canada and facilitates access to billing records from Canadian network operators, but has no involvement in the design, conduct, analysis, or interpretation of the MOBI-KIDS study. French participation was also supported by the French National Agency for Sanitary Safety of Food, Environment and Labour (ANSES, contract FSRF2008-3), French National Cancer Institute (INCa), Pfizer Foundation and League against cancer. The German study centre received additional funding from the Federal Office for Radiation Protection (BfS) under grant number 3609S30010. In Greece, the study was partially supported by the Hellenic Society for Social Pediatrics and Health Promotion, ELKE (Special Account for Research Grants of the National and Kapodistrian University of Athens) and GGET (General Secretariat for Research and Technology). Mobi-Kids India was supported by Board of Research in Nuclear Sciences (BRNS, sanction no: 2013/38/01-BRNS).

Published
2022

10. Effect of antiviral treatment in older patients hospitalized with confirmed influenza

Author

Soldevila, Núria, primary, Toledo, Diana, additional, Ortiz de Lejarazu, Raúl, additional, Tamames, Sonia, additional, Castilla, Jesús, additional, Astray, Jenaro, additional, Fernández, Maria Amelia, additional, Martín, Vicente, additional, Egurrola, Mikel, additional, Morales Suárez-Varela, María, additional, Domínguez, Àngela, additional, Mayoral, J.M., additional, Díaz-Borrego, J., additional, Morillo, A., additional, Pérez-Lozano, M.J., additional, Gutiérrez, J., additional, Pérez-Ruiz, M., additional, Fernández-Sierra, M.A., additional, Tamames, S., additional, Rojo-Rello, S., additional, Ortiz de Lejarazu, R., additional, Fernández-Natal, M.I., additional, Fernández-Villa, T., additional, Pueyo, A., additional, Martin, Vicente, additional, Vilella, A., additional, Campins, M., additional, Antón, A., additional, Navarro, G., additional, Riera, M., additional, Espejo, E., additional, Mas, M.D., additional, Pérez, R., additional, Cayla, J.A., additional, Rius, C., additional, Godoy, P., additional, Torner, N., additional, Izquierdo, C., additional, Torra, R., additional, Force, L., additional, Domínguez, A., additional, Soldevila, N., additional, Crespo, I., additional, Toledo, D., additional, Astray, J., additional, Domínguez-Berjon, M.F., additional, Gutiérrez, M.A., additional, Jiménez, S., additional, Gil, E., additional, Martín, F., additional, Génova-Maleras, R., additional, Prados, M.C., additional, Enzzine de Blas, F., additional, Salvador, M.A., additional, Galán, J.C., additional, Navas, E., additional, Rodríguez, L., additional, Álvarez, C.J., additional, Banderas, E., additional, Fernandez, S., additional, Chamorro, J., additional, Casado, I., additional, Díaz, J., additional, Castilla, J., additional, Egurrola, M., additional, López de Goicoechea, M.J., additional, Morales-Suárez-Varela, M., additional, and Sanz, F., additional

Published
2020
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17. Central nervous system (CNS) cancer in children and young people in the European Union and its involvements with socio-economic and environmental factors

Author

Llopis-González A, Alcaide Capilla T, Chenlo Alonso U, Rubio-López N, Alegre-Martinez A, and Morales Suárez-Varela M

Abstract

Malignant central nervous system (CNS) tumors are the leading cause of death by cancer in children and the second commonest pediatric cancer type. Despite several decades of epidemiologic research, the etiology of childhood CNS tumors is still largely unknown. A few genetic syndromes and therapeutic ionizing radiation are thought to account for 5-10% of childhood cancer, but the etiology of other cases remains unknown. Nongenetic causes, like environmental agents, are thought to explain them. However, as very few epidemiologic studies have been conducted, it is not surprising that nongenetic risk factors have not been detected. The biggest difference between cancers for which there are good etiologic clues and those for which there are none could be the number of relevant studies. This study, which covers the 1980-2011 period, identified links between CNS cancer evolution and the socioeconomic and environmental indicators in the same space and time limits in the European Union. (C) 2015 Elsevier B.V. All rights reserved.

Published
2015

29. Variaciones geográficas en la prevalencia de síntomas de asma en los niños y adolescentes españoles. International Study of Asthma and Allergies in Childhood (ISAAC) fase III España

Author

Carvajal-Urueña, I., primary, García-Marcos, L., additional, Busquets-Monge, R., additional, Morales Suárez-Varela, M., additional, García de Andoin, N., additional, Batlles-Garrido, J., additional, Blanco-Quirós, A., additional, López-Silvarrey, A., additional, García-Hernández, G., additional, Guillén-Grima, F., additional, González-Díaz, C., additional, and Bellido-Blasco, J., additional

Published
2005
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30. Geographic Variation in the Prevalence of Asthma Symptoms in Spanish Children and Adolescents. International Study of Asthma and Allergies in Childhood (ISAAC) Phase 3, Spain

Author

Carvajal-Urueña, I., primary, García-Marcos, L., additional, Busquets-Monge, R., additional, Morales Suárez-Varela, M., additional, García de Andoin, N., additional, Batlles-Garrido, J., additional, Blanco-Quirós, A., additional, López-Silvarrey, A., additional, García-Hernández, G., additional, Guillén-Grima, F., additional, González-Díaz, C., additional, and Bellido-Blasco, J., additional

Published
2005
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31. Tendencia temporal y variaciones geográficas de la prevalencia de síntomas de rinitis alérgica en escolares de 6-7 años de ocho áreas españolas, según el ISAAC

Author

Arnedo-Pena, A., primary, García-Marcos, L., additional, García Hernández, G., additional, Aguinagua Ontoso, I., additional, González Díaz, C., additional, Morales Suárez-Varela, M., additional, Domínguez Aurrecoechea, B., additional, Busquets Monge, R., additional, Blanco Quiros, A., additional, Batlles Garrido, J., additional, Miner Kanflanka, I., additional, and López-Silvarrey Varela, A., additional

Published
2005
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