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Your search keyword '"Nicola Ramenatte"' showing total 2 results
Start Over Author "Nicola Ramenatte" Publisher elsevier bv
2 results on '"Nicola Ramenatte"'

1. CamBMT1: A proof-of-principle phase 1b / randomised phase 2 study of afatinib penetration into brain metastases (mets) for patients undergoing neurosurgical resection, both with and without prior low-dose, targeted radiotherapy

Author

A Jonson, Gillian A Whitfield, J Garcia-Corbacho, Simon Pacey, Rajesh Jena, D. Smith, Duncan I. Jodrell, Stephen J. Price, Saif S Ahmad, Martin J. Graves, Tomasz Matys, Wendi Qian, Sarah Jefferies, Richard D. Baird, Sudhir Kumar, Carlos Caldas, Anthony J. Chalmers, Colin Watts, Constanza Linossi, and Nicola Ramenatte

Subjects
medicine.medical_specialty, business.industry, Targeted Radiotherapy, Afatinib, Low dose, Phases of clinical research, Hematology, Penetration (firestop), Surgery, Resection, Oncology, medicine, Radiology, business, medicine.drug
Published
2016
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2. MECHANISMS OF HYPERTENSION FOLLOWING VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITION: THE HYPAZ TRIAL

Author

Kaisa M. Mäki-Petäjä, Simon Bond, Lucy Yang, Fraz Mir, Annette Hubsch, Adam McGeoch, Parag R Gajendragadkar, Joseph Cheriyan, Gayathri Anandappa, Nicola Ramenatte, Ian B. Wilkinson, Duncan I. Jodrell, and Carmel M. McEniery

Subjects
biology, business.industry, VEGF receptors, Cancer, Pharmacology, medicine.disease, Nitric oxide, Vascular endothelial growth factor, chemistry.chemical_compound, Blood pressure, chemistry, biology.protein, Medicine, Endothelial dysfunction, Cardiology and Cardiovascular Medicine, business
Abstract

Vascular endothelial growth factor (VEGF) promotes nitric oxide activity. VEGF inhibitors are anti-cancer drugs that often cause hypertension but mechanisms are unclear. We hypothesised that VEGF inhibition leads to endothelial dysfunction, thus increasing blood pressure. 27 normotensive cancer

Published
2016
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