1. Binuclear copper(II) complexes 1: Synthesis, characterization and evaluation of a new complex in phosphatase-like activity
- Author
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Marius Réglier, Bruno Faure, Michel Giorgi, A. Jalila Simaan, Olivier Schicke, Institut des Sciences Moléculaires de Marseille (ISM2), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC), Spectropôle - Aix Marseille Université (AMU SPEC), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), and Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
010405 organic chemistry ,Stereochemistry ,Ligand ,Phosphatase ,chemistry.chemical_element ,010402 general chemistry ,Phosphate ,01 natural sciences ,Medicinal chemistry ,Copper ,0104 chemical sciences ,Catalysis ,Inorganic Chemistry ,Hydrolysis ,chemistry.chemical_compound ,chemistry ,Materials Chemistry ,[CHIM]Chemical Sciences ,Physical and Theoretical Chemistry - Abstract
International audience; A new binuclear Cu(II) complex derived from a pamoic type ligand has been synthesized and characterized by X-ray crystallography. This complex was checked as catalysts in the hydrolysis of bis(p-nitro-phenyl)phosphate. Its catalytic properties were studied at various pH and compared to the mononuclear Cu(II) complex. At pH 5.38, the binuclear Cu(II) complex exhibited a phosphatase-like activity with 11 TON and 24% conversion and was found to be 41-fold more active than the mononuclear counterpart.
- Published
- 2012
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