40 results on '"Otonkoski Timo"'
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2. Gene expression signature predicts rate of type 1 diabetes progression
3. Comprehensive characterization of the embryonic factor LEUTX
4. Differentiating functional human islet-like aggregates from pluripotent stem cells
5. Steroidogenic factor 1 (NR5A1) induces multiple transcriptional changes during differentiation of human gonadal-like cells
6. Transient DUX4 expression in human embryonic stem cells induces blastomere-like expression program that is marked by SLC34A2
7. DUX4 is a multifunctional factor priming human embryonic genome activation
8. CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells
9. Simultaneous high-efficiency base editing and reprogramming of patient fibroblasts
10. ALS and Parkinson's disease genes CHCHD10 and CHCHD2 modify synaptic transcriptomes in human iPSC-derived motor neurons
11. Islet Gene View - A Tool to Facilitate Islet Research
12. Generation of an OCT4 reporter human induced pluripotent stem cell line using CRISPR/SpCas9
13. A Strong Contractile Actin Fence and Large Adhesions Direct Human Pluripotent Colony Morphology and Adhesion
14. Generation of a SOX2 reporter human induced pluripotent stem cell line using CRISPR/SaCas9
15. Cerebral Organoids for Modelling Human Brain Development and Drugs Activity
16. An Activating STAT3 Mutation Causes Neonatal Diabetes through Premature Induction of Pancreatic Differentiation
17. Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential
18. Human pluripotent stem cell based islet models for diabetes research
19. Conditionally Stabilized dCas9 Activator for Controlling Gene Expression in Human Cell Reprogramming and Differentiation
20. Generation of iPSC line HEL24.3 from human neonatal foreskin fibroblasts
21. Combined negative effect of donor age and time in culture on the reprogramming efficiency into induced pluripotent stem cells
22. Generation of iPSC line HEL47.2 from healthy human adult fibroblasts
23. mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling
24. MANF Is Indispensable for the Proliferation and Survival of Pancreatic β Cells
25. Activin A and Wnt-dependent specification of human definitive endoderm cells
26. High-throughput karyotyping of human pluripotent stem cells
27. Proliferation and plasticity of human beta cells on physiologically occurring laminin isoforms
28. Laminin-511 expression is associated with the functionality of feeder cells in human embryonic stem cell culture
29. Weighing up β-cell mass in mice and humans: Self-renewal, progenitors or stem cells?
30. Physical Exercise–Induced Hypoglycemia Caused by Failed Silencing of Monocarboxylate Transporter 1 in Pancreatic β Cells
31. Maturation of in vitro-generated human islets after transplantation in nude mice
32. Over- and Underdosage of SOX3 Is Associated with Infundibular Hypoplasia and Hypopituitarism
33. Transcription factor GATA-6 is expressed in the endocrine and GATA-4 in the exocrine pancreas
34. The IIIb isoform of fibroblast growth factor receptor 2 is required for proper growth and branching of pancreatic ductal epithelium but not for differentiation of exocrine or endocrine cells
35. A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1
36. Dose-dependent cysteine-mediated protection of insulin-producing cells from damage by hydrogen peroxide
37. Carriers of an inactivating beta-cell K-ATP channel mutation have normally regulated insulin secretion
38. Dominantly inherited form of hyperinsulinism caused by a gene mutation in the sulfonylurea receptor 1
39. Transcription factor expression and hormone production in pancreatic AR42J cells
40. Lack of glucose-induced functional maturation during long-term culture of human fetal islet cells
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