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2. Clinical experience with different pegylated interferons: Is there a difference?

Author

Gamal Esmat, A. Fateen, and P.L. Almasio

Subjects
Hepatitis, Hepatology, business.industry, Hepatitis C virus, Treatment outcome, Gastroenterology, medicine.disease_cause, medicine.disease, Asymptomatic, Key point, Chronic disease, Immunology, Medicine, Acute hepatitis C, medicine.symptom, business
Abstract

The acute phase of hepatitis C virus (HCV) infection represents a key point in the evolution of hepatitis C. The infection either resolves spontaneously, or progresses into chronic disease. However, the asymptomatic nature of acute hepatitis C contributes to difficulties in detection, diagnosis and hence, the assessment of therapy when indicated. Controversies in chronic HCV related to the implications of both selected predictors of treatment outcome and clinical experience with structurally different Peg-IFNs are discussed.

Published
2009

5. OC.12.2 HLA TESTING IN ADULT-ONSET CELIAC DESEASE: RELATIONSHIP WITH CLINICAL PRESENTATION AND MUCOSAL DAMAGE

Author

Maria Cappello, V. Provenzano, Gaetano Cristian Morreale, P.L. Almasio, A. Scorsone, S. Cutrera, and A. Arini

Subjects
03 medical and health sciences, medicine.medical_specialty, 0302 clinical medicine, Hla testing, Hepatology, business.industry, 030220 oncology & carcinogenesis, Gastroenterology, medicine, 030211 gastroenterology & hepatology, Presentation (obstetrics), business, Dermatology
Published
2016

7. P.01.1 A SINGLE INFUSION OF FERRIC CARBOXYMALTOSE EFFECTIVELY IMPROVES IRON-DEFICIENCY ANEMIA IN PATIENTS WITH GASTROINTESTINAL AND LIVER DISEASE: A HOSPITAL-BASED SURVEY

Author

Maria Cappello, P.L. Almasio, M.G. Cilluffo, A. Viola, M. Mendolaro, and Antonio Craxì

Subjects
medicine.medical_specialty, Hepatology, business.industry, Gastroenterology, Hospital based, medicine.disease, FERRIC CARBOXYMALTOSE, Liver disease, Iron-deficiency anemia, Internal medicine, medicine, In patient, business
Published
2016

8. Effectiveness of Beta-Blockers in Primary Prevention of Bleeding: A Comparison of Propranol Vs. Carvedilol by HVPG

Author

P.L. Almasio, Antonio Craxì, F. Simone, Vincenza Calvaruso, A. Bonaccorso, G. Butera, and V. Di Marco

Subjects
medicine.medical_specialty, Hepatology, business.industry, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Primary prevention, Internal medicine, medicine, 030212 general & internal medicine, Beta (finance), business, Carvedilol, 030217 neurology & neurosurgery, medicine.drug
Published
2016

10. Is autoimmune chronic active hepatitis a HCV-related disease?

Author

S. Magrin, G. Pinzello, Giuseppe Provenzano, Luigi Pagliaro, G. Fiorentino, Carmelo Fabiano, P.L. Almasio, U. Palazzo, and Antonio Craxì

Subjects
Adult, Male, Immunoblotting, Enzyme-Linked Immunosorbent Assay, Virus, Autoimmune Diseases, Pathogenesis, Adrenal Cortex Hormones, Antibody Specificity, Immunopathology, Prevalence, Humans, Medicine, Clinical significance, Hepatitis Antibodies, Hepatitis, Chronic, Hepatitis, Autoimmune disease, Hepatology, biology, business.industry, virus diseases, Middle Aged, medicine.disease, Hepatitis C, digestive system diseases, Antibodies, Antinuclear, Immunology, Prednisolone, biology.protein, Female, gamma-Globulins, Antibody, business, medicine.drug
Abstract

We evaluated the specificity and clinical relevance of anti-hepatitis C virus antibody positivity in 22 HBsAg-negative patients with autoimmune (anti-nuclear, anti-actin or anti-liver-kidney microsomal antibody positive) chronic active hepatitis. An ELISA anti-HCV test and a recombinant immunoblot assay (RIBA-HCV) were used. Thirteen patients (59%) were anti-HCV positive and five (23%) anti-HCV negative by both ELISA and RIBA-HCV tests. Four patients (18%) were borderline positive by ELISA (OD less than 1.0), and three of them (all with severe disease) were negative by RIBA. Histologic necroinflammation, AST/ALT and gamma-globulins levels were higher and response to prednisolone treatment was better in RIBA anti-HCV-negative than in anti-HCV-positive cases. We confirmed with both RIBA and ELISA tests the high prevalence of anti-HCV already reported by ELISA in anti-nuclear and anti-liver-kidney microsomal antibody positive chronic active hepatitis. False positive for anti-HCV (i.e., a positive ELISA test not confirmed by RIBA) occurred only among patients with severe disease. Since RIBA-negative subjects showed the best response to corticosteroid, they might represent the only subset of cases of 'true' autoimmune chronic active hepatitis.

Published
1991

12. OC.08.6 EFFICACY OF INFLIXIMAB IN 'REAL PRACTICE' PATIENTS WITH MODERATE-TO-SEVERE ULCERATIVE COLITIS: A RETROSPECTIVE MULTICENTER STUDY FROM SOUTHERN ITALY

Author

Walter Fries, Marta Mazza, Fabrizio Bossa, Fabiana Castiglione, M. Mastronardi, N. Buccianti, A.C. Privitera, Maria Cappello, Giuseppe Costantino, P.L. Almasio, A. Lauria, R. Marasco, and Antonio Rispo

Subjects
Moderate to severe, medicine.medical_specialty, Hepatology, Multicenter study, business.industry, Internal medicine, Gastroenterology, medicine, medicine.disease, business, Ulcerative colitis, Infliximab, medicine.drug
Published
2013

13. F-17 Clinical outcome of liver damage in pregnancy: experience from a prospective cohort study

Author

R. Venezia, Antonio Craxì, P.L. Almasio, G. Licata, G. Pecoraro, M.P. Imbergamo, R.D. Vitello, A. Licata, D. Mannino, A. Perino, and Andrea Costantino

Subjects
medicine.medical_specialty, Pregnancy, Hepatology, business.industry, Internal medicine, Gastroenterology, medicine, Retrospective cohort study, Liver damage, business, medicine.disease, Prospective cohort study, Outcome (game theory)
Published
2012

14. Effectiveness of beta-blocker in primary prevention of variceal bleeding in patients with cirrhosis: A prospective evaluation by hepatic venous pressure gradient measurement

Author

R. Orlando, P.L. Almasio, Antonio Craxì, F. Simone, G. Butera, M. De Cicco, V. Di Marco, Vincenza Calvaruso, and A. Bonaccorso

Subjects
medicine.medical_specialty, Variceal bleeding, Cirrhosis, Hepatology, business.industry, medicine.drug_class, Portal venous pressure, Gastroenterology, medicine.disease, Prospective evaluation, Internal medicine, Primary prevention, Medicine, In patient, business, Beta blocker
Published
2014

15. P.06.23 INFLIXIMAB IN STEROID-DEPENDENT ULCERATIVE COLITIS: LACK OF PREDICTIVE FACTORS FOR RESPONSE IN A LARGE MULTICENTER SERIES

Author

M. Mastronardi, N. Buccianti, Maria Cappello, Fabrizio Bossa, Giuseppe Costantino, Marta Mazza, Antonio Rispo, A.C. Privitera, Walter Fries, P.L. Almasio, Mariabeatrice Principi, R. Marasco, Fabiana Castiglione, A. Lauria, and Laurino Grossi

Subjects
Series (stratigraphy), medicine.medical_specialty, Hepatology, business.industry, Gastroenterology, medicine.disease, Ulcerative colitis, Infliximab, Steroid dependency, Internal medicine, medicine, business, medicine.drug
Published
2014

16. P.02.9 ADULT-ONSET CELIAC DISEASE IN A MEDITERRANEAN POPULATION: CLINICAL, SEROLOGICAL, AND HISTOLOGICAL FEATURES AMONG DIFFERENT AGE GROUPS

Author

A. Arini, V. Provenzano, Antonio Craxì, Gaetano Cristian Morreale, P.L. Almasio, G. Giacopelli, A. Licata, Maria Cappello, and A. Scorsone

Subjects
Mediterranean climate, medicine.medical_specialty, Pathology, education.field_of_study, Hepatology, business.industry, Population, Gastroenterology, Disease, Serology, Age groups, Internal medicine, medicine, business, education
Published
2014

17. 8 PREDICTING MORTALITY RISK IN CIRRHOTIC PATIENTS SINCE THE FIRST DECOMPENSATION BASED ON A NEW PROGNOSTIC SCORE: THE AISF-EPASCO PROSPECTIVE MULTICENTRE STUDY

Author

M. De Luca, Simone Saibeni, Carmen Vandelli, S. Bruno, Massimo Cazzaniga, Maria Cristina Vinci, Martina Felder, S. Boccia, Marcello Persico, Giorgio Bellati, Tommaso Stroffolini, P.L. Almasio, A. Amato, and Guido Colloredo

Subjects
medicine.medical_specialty, Hepatology, business.industry, Internal medicine, Gastroenterology, medicine, Decompensation, business, Prognostic score
Published
2010

19. T.N.31 SUSTAINED VIROLOGIC RESPONSE PREVENTS THE DEVELOPMENT OF ESOPHAGEAL VARICES IN COMPENSATED, CHILD–PUGH CLASS A HCV-INDUCED CIRRHOSIS. A TWELVE-YEAR PROSPECTIVE FOLLOW-UP STUDY

Author

R. De Franchis, Sonia Rossi, Savino Bruno, Luigi Roffi, Patrick Maisonneuve, P.L. Almasio, Andrea Crosignani, C. Facciotto, and Alessandro Redaelli

Subjects
medicine.medical_specialty, Esophageal varices, Cirrhosis, Hepatology, business.industry, Internal medicine, Virologic response, Gastroenterology, medicine, Follow up studies, medicine.disease, business
Published
2010

20. 630 SERUM BLYS/BAFF LEVELS IN ACUTE HEPATITIS C PREDICT CLINICAL OUTCOME

Author

A. Iacò, R. Di Stefano, A. Ciaccio, F. D’Antoni, V. Di Marco, Giuseppe Tarantino, A. Licata, P.L. Almasio, Antonio Craxì, F. Barbaria, and S. Petta

Subjects
Hepatology, business.industry, Immunology, Medicine, Acute hepatitis C, business, B-cell activating factor
Published
2008

23. OC-34 Clinical features and outcome of patients with drug-induced autoimmune hepatitis

Author

Fabio Salvatore Macaluso, A. Licata, P.L. Almasio, G. Butera, Antonio Craxì, and Daniela Cabibi

Subjects
Drug, medicine.medical_specialty, Hepatology, business.industry, media_common.quotation_subject, Internal medicine, Gastroenterology, Medicine, Autoimmune hepatitis, business, medicine.disease, Outcome (game theory), media_common
Published
2012

25. 497 PATTERN OF DRUG-INDUCED LIVER INJURY: THE IMPACT OF AMOXICILLIN-CLAVULANATE ON SEVERITY OF CLINICAL COURSE

Author

Maria Cappello, Claudia Randazzo, P.L. Almasio, A. Calì, G. Butera, A. Licata, Antonio Craxì, and Vincenza Calvaruso

Subjects
Drug, Liver injury, medicine.medical_specialty, AMOXICILLIN/CLAVULANATE, Hepatology, business.industry, media_common.quotation_subject, Clinical course, medicine.disease, Gastroenterology, Internal medicine, medicine, business, media_common
Published
2011

26. P.1.173: FORMATION OF NON-ORGAN SPECIFIC AUTOANTIBODIES (NOSA) IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE (IBD) TREATED WITH ANTI-TUMOR NECROSIS FACTOR-ALPHA AGENTS

Author

Maria Cappello, I. Bravatà, Claudia Randazzo, A. Licata, P.L. Almasio, Antonio Craxì, and F. Barbaria

Subjects
Anti tumor necrosis factor alpha, Hepatology, business.industry, Immunology, Organ specific, Gastroenterology, Autoantibody, Medicine, In patient, business, medicine.disease, Inflammatory bowel disease
Published
2011

28. F-2 Pattern of drug-induced liver injury: The impact of amoxicillin-clavulanate on clinical course

Author

G. Butera, A. Licata, Maria Cappello, Claudia Randazzo, A. Calì, Vincenza Calvaruso, Antonio Craxì, and P.L. Almasio

Subjects
Liver injury, Drug, medicine.medical_specialty, AMOXICILLIN/CLAVULANATE, Hepatology, business.industry, media_common.quotation_subject, Gastroenterology, Clinical course, medicine.disease, Internal medicine, medicine, business, media_common
Published
2011

29. 389 LONG-TERM EVALUATION OF FIBROSIS BY TRANSIENT ELASTOGRAPHY IN PATIENTS CLEARING HCV ON ANTIVIRAL THERAPY

Author

Antonio Craxì, R. Di Stefano, V. Di Marco, Vincenza Calvaruso, Claudia Cottone, A. Calì, Paola Pizzillo, P.L. Almasio, and S. Petta

Subjects
medicine.medical_specialty, Cirrhosis, Hepatology, Bilirubin, business.industry, medicine.disease, Gastroenterology, chemistry.chemical_compound, Esophageal varices, chemistry, Fibrosis, Internal medicine, medicine, Portal hypertension, In patient, Varices, Transient elastography, business
Abstract

was unreliable in 15 obese patients(8.9%). 54 patients (37.5%) had an histological and 90 (62.5%) a clinical diagnosis of cirrhosis. All patients underwent endoscopy. LS and SS were measured under US control. Results: In the subgroup with haemodinamic evaluation, we found a significant correlation between HVPG value and SSM(Linear regression analysis: r = 0.671; p =0.009). 9 of them had the highest SS value(75 kPa). Mean HVPG was significant different between patients with SSM lower or equal 75 kPa(12.5mmHg vs 19.1mmHg, p =0.013) without significant differences for bilirubin, albumin or INR values(p=ns). All 9 patients with SSM=75kPa had large esophageal varices(6 F2, 3 F3). In the whole cohort of patients, 80 (55.6%) had EV and 28 (19.4%) had large EV(F2 or F3). The AUROCs of LS and SS were almost the same(0.76 vs 0.73) for the prediction of EV but SSM was significantly better than LSM to predict large EV(AUROCs:0.84 vs 0.72). The best cut-offs of LS and SS for the diagnosis of cirrhosis with EV were 21kPa(Sens. 71%, Spec. 72%) and 47kPa(Sens. 79%, Spec. 70%) respectively. Twenty-four patients with a LSM

Published
2010

30. F.N.7 ONE-YEAR MORTALITY RATE IN PATIENTS WITH STAGE 3 AND 4 CIRRHOSIS: THE ITALIAN ASSOCIATION FOR THE STUDY OF LIVER (AISF)-EPASCO PROSPECTIVE MULTICENTRE STUDY

Author

M. De Luca, P.L. Almasio, Tommaso Stroffolini, A. Mega, Simone Saibeni, Cleofe Prisco, M. Sonzogni, Anna Ludovica Fracanzani, S. Bruno, R. Bottelli, Giovanna Vitaliani, Carmen Vandelli, Marcello Persico, and L. Simone

Subjects
One year mortality, medicine.medical_specialty, Cirrhosis, Hepatology, business.industry, Internal medicine, Gastroenterology, Medicine, In patient, Stage (cooking), business, medicine.disease
Published
2010

31. 602 THE CANDIDATE HCV E1E2MF59 VACCINE IS SAFE IN CHRONIC HEPATITIS C PATIENTS AND ACCELLERATES THE SECOND PHASE VIRAL DECLINE UPON PRIMARY RESPONSE TO PEG-INTERFERON-2A/RIBAVIRIN THERAPY

Author

M. Sarracino, Piero Colombatto, Sergio Abrignani, Michael Houghton, S. Madonia, Vincenzo Barnaba, Rino Rappuoli, A.M. Maina, P.L. Almasio, Mario U. Mondelli, F.B. Bianchi, María Isabel Colombo, Antonio Craxì, S. Montigiani, Veronica Romagnoli, Ferruccio Bonino, G. Pinzello, M.G. Rumi, Alba Muzzi, Silvia Fargion, Domenico Rosa, Maurizia Rossana Brunetto, and Antonio Ascione

Subjects
chemistry.chemical_compound, Peg interferon, Hepatology, chemistry, Chronic hepatitis, business.industry, Ribavirin, Primary response, Medicine, business, Virology
Published
2009

32. Retrospective, observational, multicentre study on the Italian population affected by chronic hepatitis C who failed to clear HCV-RNA after the combination therapy (PEG-IFN and ribavirin): Nadir study

Author

Tommaso Stroffolini, Massimo Zuin, Filomena Morisco, D. Caterina Amoruso, Maria Stanzione, Erica Villa, E. Medda, B. Paris, Nicola Caporaso, and P.L. Almasio

Subjects
medicine.medical_specialty, Hepatology, Combination therapy, business.industry, Ribavirin, Gastroenterology, Italian population, Surgery, chemistry.chemical_compound, Chronic hepatitis, chemistry, Internal medicine, medicine, Observational study, business, Nadir (topography)
Published
2009

33. The candidate HCV E1E2MF59 vaccine enhances 2nd phase viral decline in responders to PEG-IFN/ribavirin

Author

Maurizia Rossana Brunetto, A.M. Maina, Veronica Romagnoli, Domenico Rosa, F.B. Bianchi, Ferruccio Bonino, P.L. Almasio, Antonio Ascione, Silvia Fargion, Piero Colombatto, Vincenzo Barnaba, A. Muzzi, Salvatore Madonia, Sergio Abrignani, S. Montigiani, Mario U. Mondelli, Giovanbattista Pinzello, M. Colombo, Michael Houghton, Antonio Craxì, Rino Rappuoli, M. Sarracino, and Maria Grazia Rumi

Subjects
chemistry.chemical_compound, Hepatology, chemistry, business.industry, Ribavirin, Gastroenterology, Medicine, business, Virology
Published
2009

34. Non-invasive assessment of the liver fibrosis by transient elastography (TE) in patients with transfusion-dependent thalassemia

Author

P.L. Almasio, Aurelio Maggio, Zelia Borsellino, Antonio Craxì, Fabrizio Bronte, Francesco Gagliardotto, Giuseppe Alaimo, Vincenza Calvaruso, V. Di Marco, Donatella Ferraro, F. Barbaria, Marcello Capra, and Daniela Cabibi

Subjects
medicine.medical_specialty, Hepatology, business.industry, Internal medicine, Liver fibrosis, Non invasive, Gastroenterology, medicine, Transfusion dependent thalassemia, In patient, business, Transient elastography
Published
2008

35. Demographic, etiological and clinical features of liver cirrhosis at the onset of the first episode of clinical decompensation: Preliminary results of the 'A.I.S.F.-EPASCO' Study

Author

Francesco Salerno, Tommaso Stroffolini, Savino Bruno, Antonio Ascione, Carmela Loguercio, G.B. Gaeta, P.L. Almasio, M. Tommasini, Caterina Furlan, Angelo Andriulli, Pietro Andreone, Simone Saibeni, Martina Felder, Carmen Vandelli, and Marcello Persico

Subjects
First episode, medicine.medical_specialty, Cirrhosis, Hepatology, business.industry, medicine.medical_treatment, Gastroenterology, Stent, medicine.disease, Portal vein thrombosis, Hepatocellular carcinoma, Internal medicine, medicine, Etiology, Portal hypertension, Decompensation, business
Abstract

p, TIPS dysfunction was observed in two patients: in one, ith recurrent features of intestinal ischaemia, the shunt was orrected with an additional stent. In the other one, with recurent variceal bleeding, a spleno-renal shunt was performed. ne patient developed two episodes of hepatic encephalopahy few days after the procedure. One patient died after nine onths for hepatocellular carcinoma. onclusions. TIPS is technically feasible in the majority of atients with chronic portal vein thrombosis and portal caveroma and may be considered among the therapeutic options f this infrequent cause of portal hypertension.

Published
2008

36. [681] STAGING OF FIBROSIS BY LIVER STIFFNESS MEASUREMENT IN THALASSEMICS WITH IRON OVERLOAD

Author

S. Ciminnisi, Marcello Capra, P.L. Almasio, Aurelio Maggio, Daniela Cabibi, F. Barbaria, Antonio Craxì, V. Di Marco, Fabrizio Bronte, Giuseppe Alaimo, and Zelia Borsellino

Subjects
medicine.medical_specialty, Hepatology, business.industry, Liver stiffness, Fibrosis, Internal medicine, medicine, business, medicine.disease, Gastroenterology
Published
2007

37. [224] THE IMPACT OF SUSTAINED VIROLOGICAL RESPONSE ON CLINICAL OUTCOMES IN COMPENSATED HCV CIRRHOSIS: A PROSPECTIVE COHORT STUDY

Author

P.L. Almasio, N. Alessi, Antonio Craxì, S. Peralta, R. Di Stefano, S. De Lisi, V. Di Marco, Giuseppe Alaimo, Donatella Ferraro, Vincenza Calvaruso, and P. Parisi

Subjects
Virological response, medicine.medical_specialty, Cirrhosis, Hepatology, business.industry, Internal medicine, medicine, medicine.disease, Prospective cohort study, business
Published
2007

38. 614 Kinetic analysis of insulin resistance and serum adipocytokines levels during peginterferon alpha-2A plus ribavirin therapy in non-diabetic HCV patients

Author

A. Mattina, S. De Lisi, Antonio Craxì, Maria Pia Amato, V. Di Marco, O. Lo Iacono, A. Licata, G. Venezia, Donatella Ferraro, P.L. Almasio, C. Minco, and S. Petta

Subjects
medicine.medical_specialty, Hepatology, business.industry, Ribavirin, Kinetic analysis, Adipokine, Peginterferon alpha-2a, medicine.disease, Gastroenterology, chemistry.chemical_compound, Insulin resistance, chemistry, Internal medicine, medicine, business, Non diabetic
Published
2006

39. 478 Treating chronic hepatitis C in daily practice with PEG-IFN alfa2B and ribavirin. An Italian multicentre study

Author

G. Stornaiuolo, Felice Piccinino, N. Carannante, A. Amato, Maria Stanzione, G. B. Gaeta, Df Precone, Nicola Caporaso, Marcello Persico, and P.L. Almasio

Subjects
chemistry.chemical_compound, medicine.medical_specialty, Hepatology, chemistry, Chronic hepatitis, business.industry, Ribavirin, Internal medicine, Daily practice, medicine, business, Gastroenterology
Published
2004

43. Hepatitis C virus replication in chronic liver disease

Author

Maria Vitale, Aurelio Maggio, Carmelo Fabiano, Luigi Pagliaro, S. Magrin, Giuseppe Provenzano, Antonio Craxì, O. Lo Iacono, G. Fiorentino, V. Di Marco, L Marino, P.L. Almasio, R. Bruno, U. Palazzo, and G. Pinzello

Subjects
Male, Hepatology, business.industry, Hepatitis C virus, Transfusion Reaction, Hepacivirus, Middle Aged, Virus Replication, medicine.disease_cause, Chronic liver disease, medicine.disease, Hepatitis C, Virology, Replication (statistics), medicine, Humans, RNA, Viral, Female, business
Published
1991

44. Prediction of response to alfa-interferon in chronic hepatitis C

Author

Fabio Tinè, G. Pinzello, S. Magrin, O. Lo Iacono, Raffaele Bruno, L. Pagliaro, U. Palazzo, A. Craxl, P.L. Almasio, V. Di Marco, Felice Fiorello, and C. Cammà

Subjects
Hepatology, Chronic hepatitis, business.industry, Interferon, Immunology, Medicine, business, medicine.drug
Published
1991

45. HCV replication and respone to treatment in chronic hepatitis

Author

S. Magrin, Carmelo Fabiano, Raffaele Bruno, Antonio Craxì, O. Lo Iacono, L Marino, Maria Vitale, L. Pagliaro, P.L. Almasio, G. Pinzello, Aurelio Maggio, U. Palazzo, Giuseppe Provenzano, V. Di Marco, and C. Ficrentino

Subjects
Hepatology, Chronic hepatitis, business.industry, Replication (statistics), Medicine, business, Virology
Published
1991

46. HCV deffection in 'autonimine' chronic active hepatitis

Author

Carmelo Fabiano, L. Pagliaro, G. Fiorentino, G. Provenzeno, G. Pinzello, S. Magrin, Antonio Craxì, U. Palazzo, Jang Han, P.L. Almasio, and Michael Houghton

Subjects
Hepatitis, Hepatology, Chronic Active, business.industry, Immunology, medicine, medicine.disease, business
Published
1990

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